• The chemotherapeutic analogue (combining chemotherapy with embolization) is called chemoembolization, of which transcatheter arterial chemoembolization (TACE) is the usual form. (wikipedia.org)
  • This area should be included in the treatment, constituting some "safety margin" at the periphery of the target tumour, such as in surgery, radiofrequency ablation (RFA) and TACE. (springer.com)
  • Methods: Patients were assigned to treatment with transcatheter arterial chemoembolization (TACE) combined with 131I-metuximab or TACE alone. (bvsalud.org)
  • Combined SBRT and immunotherapy resulted in significantly superior survival and less toxicity compared with transcatheter arterial chemoembolization (TACE) [ 14 ]. (biomedcentral.com)
  • This review summarizes the different IR treatment options in HCC, including various ablative therapies, Transarterial Chemoembolization (TACE), Transarterial Radioembolization (TARE), Portal Vein embolization, emphasizing patient selection, procedural considerations and response evaluation. (thieme-connect.de)
  • The aim is to evaluate effects and safety of the combination of transcather arterial chemoembolization (TACE) and percutaneous ethanol-lipiodol injection (PELI) for the treatment of unresectable hepatocellular carcinoma (HCC). (volksonpress.com)
  • Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Does TACE Have a Future? (benthambooks.com)
  • Background To determine the safety and efficacy of transarterial chemoembolization (TACE) combined with radiofrequency ablation (hereafter, TACE-RFA) in treating Barcelona Clinic Liver Cancer (BCLC) Stage A or B (hereafter, BCLC A/B) hepatocellular carcinoma (HCC) patients, and to explore the range of tumor sizes suitable for combination therapy. (researchsquare.com)
  • In recent years, transarterial chemoembolization (TACE) as a palliative therapy has been recognized as the standard method for patients with unresectable HCC [11,12]. (researchsquare.com)
  • TACE can improve survival by combining targeted chemotherapy with ischemic necrosis caused by arterial embolization [12,13]. (researchsquare.com)
  • To clarify the hemodynamic changes under balloon occlusion of the hepatic artery and to identify predictors of the short-term therapeutic effect (TE) after balloon-occluded transcatheter arterial chemoembolization using miriplatin (B-TACE) for hepatocellular carcinoma (HCC). (springeropen.com)
  • Therefore, other therapeutic modalities to improve the survival of such patients are being tried, including surgical resection, transarterial chemoembolization (TACE), chemotherapy, and three-dimensional conformal radiotherapy, but the clinical outcomes remain unsatisfactory. (biomedcentral.com)
  • We retrospectively evaluated the long-term effects of partial splenic embolization (PSE) with transarterial chemoembolization (TACE) in patients with HCC patients accompanied by thrombocytopenia. (hindawi.com)
  • Since cirrhotic patients with severe thrombocytopenia are at greater risk for bleeding, treatments against HCC such as liver transplantation, resection, local ablation therapy, and transarterial chemoembolization (TACE) can be performed following a platelet transfusion in those patients. (hindawi.com)
  • The aim of this study was to assess the safety and effectiveness of PSE with TACE for patients with HCC and severe thrombocytopenia. (hindawi.com)
  • Primary aim of our analysis was to evaluate the role of transarterial chemoembolization, either with lipiodol (traditional TACE) or drug-eluting microspheres (precision TACE, pTACE), in terms of response rate (RR), time to progression (TTP) and overall survival (OS), in patients with advanced HCC. (biomedcentral.com)
  • Intra-arterial transcatheter embolotherapies are recommended for non-surgical patients in the intermediate HCC stage, while sorafenib is the standard systemic herapy for patients with advanced HCC and well-preserved liver function and those with intermediate-stage HCC who progress following trans-arterial chemoembolization (TACE). (biomedcentral.com)
  • Patients with more advanced disease are currently offered palliative treatment, including localized transarterial chemoembolization (TACE) or systemic chemotherapy. (biomedcentral.com)
  • Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis. (genderi.org)
  • Can DKI-MRI predict recurrence and invasion of peritumoral zone of hepatocellular carcinoma after transcatheter arterial chemoembolization? (wjgnet.com)
  • This prospective nonrandomized, multicenter clinical trial was performed to investigate the efficacy and safety of 131I-labeled metuximab in adjuvant treatment of unresectable hepatocellular carcinoma. (bvsalud.org)
  • Aim: We investigated the efficacy and safety of hepatic artery infusion chemotherapy (HAIC) combined with anti-PD-1 immunotherapy and tyrosine kinase inhibitors (TKIs) for advanced hepatocellular carcinoma (HCC). (bvsalud.org)
  • Trans-arterial radioembolization (TARE) is a recognized, although not explicitly recommended, experimental therapy for unresectable hepatocellular carcinoma (HCC). (oncotarget.com)
  • Lipiodol trans-arterial chemoembolization of hepatocellular carcinoma with idarubicin: first experience. (im2p.fr)
  • Novel imaging biomarkers of response to transcatheter arterial chemoembolization in hepatocellular carcinoma patients. (im2p.fr)
  • Reply: Which is the Best Chemotherapeutic Agent for Transarterial Chemoembolization of Hepatocellular Carcinoma? (im2p.fr)
  • The mix of transcatheter arterial chemoembolization and sorafenib is well tolerated and effective in Asian patients with hepatocellular carcinoma: remaining outcomes of the BEGIN trial. (page.tl)
  • We evaluate the safety and efficacy of ultrasound-guided percutaneous brachytherapy with iodine-125 seeds for the treatment of hepatocellular carcinoma with portal vein-branch tumor thrombus (PVBTT). (biomedcentral.com)
  • Trans-arterial radio-embolization (TARE) is an emerging treatment for the management of hepatocellular carcinoma (HCC). (biomedcentral.com)
  • One-shot" arterial chemotherapy for members with liver metastases from colorectal cancer. (aetna.com)
  • Hepatic arterial infusion chemotherapy (HAIC) treatment is widely accepted as one of the alternative therapeutic modalities for HCC owing to its local control effect and low systemic toxicity. (bvsalud.org)
  • These include direct ablation of the tumour using agents such as ethanol or acetic acid, transcatheter arterial chemoembolization, or systemic chemotherapy. (ox.ac.uk)
  • These patients are therefore candidates treatment including transarterial embolization and chemoembolization and systemic treatments including chemotherapy, immunotherapy and hormonal therapy [ 6 ]. (biomedcentral.com)
  • TARE may compete with systemic chemotherapy, sorafenib, in intermediate stage patients with prior chemoembolization failure or advanced patients with tumoral macrovascular invasion with no extra-hepatic spread and good liver function. (biomedcentral.com)
  • The aim of the present study was to determine the status of STZ usage in Japan and to evaluate the effectiveness and safety of STZ chemotherapy in Japanese NET patients. (cancerindex.org)
  • Drug-eluting beads trans-arterial chemoembolization for leiomyosarcoma, liver metastases from colorectal cancer, and for primary and liver-dominant metastatic disease of the liver. (aetna.com)
  • Selective internal radiation therapy (SIRT), also known as transarterial radioembolization (TARE), radioembolization or intra-arterial microbrachytherapy is a form of radiation therapy used in interventional radiology to treat cancer. (wikipedia.org)
  • Considering the aggressive nature of HBV-associated HCC, multimodal and high-intensity strategies like the addition of immunotherapy-based systemic treatment to local therapies, including resection, ablation, and intra-arterial therapies, have been adopted in real-life practices in China. (e-cmh.org)
  • TARE is one type of intra-arterial brachytherapy used to treat HCC. (biomedcentral.com)
  • A: With its active ingredient extracted from seed of "semen coicis", a natural anti-tumor herbal plant, Kanglaite Injection (KLT) is a novel dual-function, broad spectrum and molecular-targeting anti-neoplastic formulation for intravenous and intra-arterial application. (kanglaite.com)
  • Therefore, locoregional therapies such as transarterial chemoembolization or radioembolization, can selectively be administered in the arteries that are supplying the tumors and will preferentially lead to deposition of the particles in the tumor, while sparing the healthy liver tissue from harmful side effects. (wikipedia.org)
  • Transarterial chemoembolization or radioembolization using Yttrium-90 can be used for patients with an incurable disease and have comparatively low adverse effects. (xiahepublishing.com)
  • A systematic literature review was performed to identify published studies on the use of TARE in intermediate and advanced stages HCC exploring the efficacy and safety of this innovative treatment. (oncotarget.com)
  • The safety analysis, focused on the risk of liver decompensation after TARE, revealed a great variability, from 0-1% to more than 36% events, influenced by the number of procedures, patient Child-Pugh stage and treatment duration. (oncotarget.com)
  • Along with systemic therapy, liver-targeted therapies for recurrent HCC including, radiofrequency, microwave ablation, transarterial chemoembolization, and stereotactic body radiation therapy are promising options. (xiahepublishing.com)
  • Safety and toxicity of the combination therapy, and its effects on survival rates, progression-free survival (PFS), and local response were evaluated. (volksonpress.com)
  • Zero toxicity and accomplish safety profiles of this wonder molecule, make it a choice of health conscious individuals as well as cancer fighting subjects without any hesitation. (nutraculture.com)
  • A further study to better determine the efficacy of this combination therapy is warranted. (volksonpress.com)
  • Efforts to improve the diagnostic sensitivity and the therapeutic efficacy of HCC treatment have contributed to a decrease of 20.3% in age-standardized mortality in China from 1990 to 2017 [ 1 ]. (e-cmh.org)
  • Therefore, we have conducted a retrospective study to evaluate the safety and effectiveness of ultrasound-guided percutaneous brachytherapy for the treatment of HCC with PVBTT. (biomedcentral.com)
  • Chemoembolization (CE) for other indications including palliative treatment of liver metastases from other non-neuroendocrine primaries (e.g., breast cancer, cervical cancer, colon cancer, esophageal cancer, melanoma, rhabdomyosarcoma, or unknown primaries) and CE of the pancreas for pancreatic cancer. (aetna.com)
  • In a phase II trial, the combination of RT with camrelizumab (an anti-PD1) for patients with unresectable HCC showed promising efficacy and acceptable safety profile, with 52.4% of patients achieving an objective response [ 13 ]. (biomedcentral.com)
  • Our survey showed the clinical benefit and safety of STZ therapy for Japanese patients with unresectable NET. (cancerindex.org)
  • Background: The purpose was to compare the efficacy and safety of hepatic arterial infusion (HAI) of oxaliplatin plus raltitrexed (TOMOX) to those of oxaliplatin plus 5-fluorouracil (FOLFOX) for unresectable colorectal cancer liver metastases (CRCLM). (bvsalud.org)
  • Following the controlled administration of intravenous contrast media, the arterial and venous phases of perfusion are imaged. (oncolink.org)
  • Subsequently, several large phase III trials have been started to evaluate the efficacy of SIRT when used earlier in the treatment scheme or in combination treatments with systemic therapy. (wikipedia.org)
  • This interim analysis focuses on feasibility of the planned statistical analysis regarding data distribution and completeness, treatment intention, safety and health-related quality of life (HRQOL) of the first 50 patients prospectively enrolled in the CIrse REgistry for LifePearlâ„¢ microspheres (CIREL), an observational multicentre study conducted across Europe. (springer.com)
  • The primary endpoint is the categorisation of treatment intention, and secondary endpoints presented in this interim analysis are safety, treatment considerations and HRQOL. (springer.com)
  • HAI of FOLFOX has similar efficacy to TOMOX, and HAI of TOMOX had shorter arterial infusion time. (bvsalud.org)
  • The evaluation of their efficacy is compromised by the paucity of adequately powered randomised clinical trials. (ox.ac.uk)
  • KLT will also be approved as an anticancer new drug since active substance, molecular structure, anticancer mechanism at molecular level, clinical efficacy and safety have been scientifically defined, extensively studied, carefully evaluated and strictly examined before approval. (kanglaite.com)
  • Featured Abstract(top 5%), In vivo Intravascular MR Imaging: Transvenous Technique for Arterial Wall Imaging. (stanford.edu)
  • During the arterial phase of the study, HCC enhances more intensely than the surrounding liver because the arterial blood in the liver is diluted by venous blood that does not contain contrast, whereas the HCC contains only arterial blood. (oncolink.org)
  • The presence of arterial uptake followed by washout in a single dynamic study is highly specific (95%-100%) for HCC of 1 to 3 cm in diameter and virtually diagnostic of HCC. (oncolink.org)
  • Endovascular stent placement for chronic post-thrombotic symptomatic ilio-femoral venous obstructive lesions: a single-center study of safety, efficacy and quality-of-life improvement. (im2p.fr)
  • The aim of the present study was to reveal the relationship between changes of arterial flow in HCC nodules under balloon occlusion and local TE by means of CTHA. (springeropen.com)
  • Purpose : We evaluated the immunogenicity and safety of eIPV(Imovax PolioⓇ) in a group of healthy Korean infants on a three-dose primary vaccination. (e-cep.org)