• The neuropeptide oxytocin (OT) has been shown to play a modulatory role in nociception. (iasp-pain.org)
  • Overall, our preliminary data may suggest that the striatum is a key structure underlying the pain-modulating effects of OT in patients with chronic pain and adds to the growing evidence linking the neuropeptide to pain modulation in humans. (iasp-pain.org)
  • The neuropeptide oxytocin (OT) is a well-described modulator of socio-emotional traits, such as anxiety, stress, social behavior, and pair-bonding, however, when dysregulated, it is associated with adverse psychiatric traits, like various aspects of autism spectrum disorder (ASD). (preprints.org)
  • The neuropeptide oxytocin (OXT) has recently emerged as playing a key role in human social cognition and behaviour. (nature.com)
  • Oxytocin (Oxt or OT) is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. (wikipedia.org)
  • An accumulating body of evidence suggests that the hypothalamic neuropeptide oxytocin (OT) has a modulatory effect on pain processing. (nih.gov)
  • The neuropeptide oxytocin (OT) is associated with a plethora of social behaviors and is a key topic at the intersection of psychology and biology. (nature.com)
  • In this study, we tested the effects of the neuropeptide oxytocin on ANS reactivity during couple conflict in a standardized laboratory paradigm. (edu.au)
  • Our results imply sex-specific effects of oxytocin on sympathetic activity, to negative couple interaction, with the neuropeptide reducing sAA responses and emotional arousal in women while increasing them in men. (edu.au)
  • We measured the hypothalamic neuropeptide oxytocin in plasma and cerebrospinal fluid (CSF) in a cohort of HD gene expansion carriers (HDGECs), compared the levels to healthy HD family controls and correlated oxytocin levels to disease progression and social cognition. (lu.se)
  • The role of oxytocin in maintaining health and wellness is huge, so this article takes you through various natural therapies for increasing the levels of oxytocin in your body. (naturaltherapypages.com.au)
  • Increased levels of oxytocin may lead to a temporary mild to moderate dilation of pupils. (healthline.com)
  • Research suggests that higher levels of oxytocin may help heighten the response to human faces. (healthline.com)
  • Increasing the body/s production of oxytocin is one avenue, and levels of oxytocin can be raised through sexual stimulation or other stimulation, depending on the individual. (online-literature.com)
  • The levels of oxytocin in CSF and blood were analyzed by radioimmunoassay. (lu.se)
  • By understanding the role of oxytocin in the mind-body connection, individuals can incorporate these natural therapy approaches into their lives to nurture emotional wellbeing and healing. (naturaltherapypages.com.au)
  • This finding, along with the identification of oxytocin receptors in CNS neurons, has spurred interest in the potential role of oxytocin in reversing memory loss tied to cognitive disorders like AD. (neurosciencenews.com)
  • These findings address two major points of the current debate on the etiology and pathogenesis of autism: the role of oxytocin, known to be involved in modeling human behavior, and the possible involvement of epigenetic mechanisms. (biomedcentral.com)
  • 2012. Effect of Administration of Oxytocin During Diestrus on Corpus Luteum Function and Endometrial Oxytocin Receptor Concentration in Cycling Mares. (equine-reproduction.com)
  • Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve β-amyloid peptide (25-35)-induced memory impairment in mice " by Chikamasa Yamashita et al. (neurosciencenews.com)
  • We conclude that long-term 3V administration of oxytocin to rats can both prevent and treat diet-induced obesity. (nih.gov)
  • Conclusions: Our results indicate that mHTT expression can exert cell-autonomous toxic effects on OXT neurons without affecting the non-motor phenotype at early time points in mice. (lu.se)
  • However, oxytocin neurons make other peptides, including corticotropin-releasing hormone (CRH) and dynorphin, for example, that act locally. (wikipedia.org)
  • The magnocellular neurons that make oxytocin are adjacent to magnocellular neurons that make vasopressin, and are similar in many respects. (wikipedia.org)
  • Background: Oxytocin is a nine-amino-acid peptide generated in hypothalamic neurons and transferred down posterior pituitary axons before being secreted into the bloodstream. (researchbib.com)
  • Oxytocin (OT) is a nonapeptide synthesized by the magno-cellular neurons located in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. (genome.jp)
  • Because the production of the two hormones is so close anatomically, disorders that cause vasopressin deficiency could also affect the neurons that produce oxytocin," explains Dr. Cihan Atila, endocrinologist and lead author of a study that has now been published in the journal Lancet Diabetes and Endocrinology . (unibas.ch)
  • Her first original research article is in press titled "Effects of mutant huntingtin in oxytocin neurons on non-motor features of Huntington's disease" in Neuropathology and Applied Neurobiology. (lu.se)
  • Zak, a professor of economics and the founding director of the Center for Neuroeconomics Studies at Claremont Graduate University in Claremont, Calif., is generally happy to talk about his research, which focuses on the effect of the hormone oxytocin on mood and emotion. (go.com)
  • Some view the hormone oxytocin as a panacea for aiding labor and delivery, lactation, maternal bonding, sexual satisfaction, social recognition, and anxiety. (psychcentral.com)
  • The hormone oxytocin is important for social interaction and to control emotions. (unibas.ch)
  • Oxytocin is a hormone of the posterior pituitary that promotes lactation, maternal bonding, and birth. (frontiersin.org)
  • In addition to causing uterine contractions and tension in the lactation glands, oxytocin causes sexual stimulation, and is produced during and after orgasm. (online-literature.com)
  • If that story by Arthur C. Clarke was correct, then producing many more people would be a problem, but there are other ways to stimulate the production of oxytocin that would not result in more humans, but that is not a subject that I need to cover here, and it might turn out that encouraging lactation for longr periods would be adequate. (online-literature.com)
  • Experimentation has shown that oxytocin, a peptide hormone primarily responsible for parturition, bonding, and lactation, also regulates cognitive behavior in the rodent central nervous system (CNS). (neurosciencenews.com)
  • Here using combined blood and cerebrospinal fluid (CSF) sampling in subjects receiving either 24 IU of oxytocin (n = 11) or placebo (n = 4) we have shown that oxytocin levels significantly increased in both plasma and CSF. (nature.com)
  • Researchers at the University of Basel and the University Hospital of Basel, led by Professor Mirjam Christ-Crain, have now shown that oxytocin levels are 8.5 times higher in healthy individuals after a single dose of MDMA, while they remain unchanged in those with vasopressin deficiency. (unibas.ch)
  • By chance, sodium ascorbate by itself was found to stimulate the production of oxytocin from ovarian tissue over a range of concentrations in a dose-dependent manner. (wikipedia.org)
  • Because of the eminent role of receptors for mediating the biological effects of steroid hormones, changes in receptor expression could alter responsiveness of the target cells and determine the physiological circumstances in which gonadal steroids become important regulators of cell function. (jneurosci.org)
  • Oxytocin receptors are thought to have evolved when ancestral women began nursing their children and stimulated oxytocin production in their bodies to ensure healthy breastfeeding after delivery. (naturaltherapypages.com.au)
  • It is now known that oxytocin receptors can occur almost ubiquitously in the organism, that oxytocin is also formed outside of the brain and that oxytocin has functions in a number of organs. (oxytocin.wiki)
  • Oxytocin induces a transient increase in cytosolic free [Ca2+] in renal tubular epithelial cells: evidence for oxytocin receptors on LLC-PK1 cells. (aspetjournals.org)
  • These data indicate that oxytocin-induced calcium transients in LLC-PK1 cells were not mediated by V1 or V2 vasopressin receptors, but by oxytocin receptors. (aspetjournals.org)
  • However, the poor correlation between antagonism at the LLC-PK1 receptors and the rat uterus oxytocin receptors suggests marked differences in antagonist recognition. (aspetjournals.org)
  • The effects on [Ca2+]i probably are not mediated by V1 and V2 vasopressin receptors, but by putative oxytocin receptors. (aspetjournals.org)
  • This is supported by the author's further comment that "Further investigation in this area may reveal potential beneficial effects of oxytocin administration in early pregnancy. (equine-reproduction.com)
  • In the 1920s, oxytocin and vasopressin were isolated from pituitary tissue and given their current names. (wikipedia.org)
  • Oxytocin and vasopressin are the only known hormones released by the human posterior pituitary gland to act at a distance. (wikipedia.org)
  • Amastatin, bestatin (ubenimex), leupeptin, and puromycin have been found to inhibit the enzymatic degradation of oxytocin, though they also inhibit the degradation of various other peptides, such as vasopressin, met-enkephalin, and dynorphin A. In the hypothalamus, oxytocin is made in magnocellular neurosecretory cells of the supraoptic and paraventricular nuclei, and is stored in Herring bodies at the axon terminals in the posterior pituitary. (wikipedia.org)
  • Systemic vasopressin (VP) and oxytocin (OT) are chiefly produced by magnocellular neurosecretory cells (MNCs) in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. (jneurosci.org)
  • The intrinsic binding ability of 7 natural peptides (oxytocin, arg8 -vasopressin, bradykinin, angiotensin-I, substance-P, somatostatin, and neurotensin) with copper in 2 different oxidation states (CuI/II ) derived from different Cu+/2+ precursor sources have been investigated for their charge-dependent binding characteristics. (2sars.com)
  • The hormones oxytocin and vasopressin are produced in the same area of the brain and are also very similar in structure. (unibas.ch)
  • Now, for the first time, researchers from the University of Basel and the University Hospital of Basel have succeeded in demonstrating a deficiency of oxytocin in patients with a deficiency of vasopressin caused by a disease of the pituitary gland. (unibas.ch)
  • Oxytocin deficiency in people with vasopressin deficiency would at least partially explain this finding," says the endocrinologist Atila. (unibas.ch)
  • The same researchers at the Department of Clinical Research are currently planning a large study to investigate whether treatment with oxytocin can improve the psychological symptoms in patients with vasopressin deficiency. (unibas.ch)
  • Oxytocin in response to MDMA provocation test in patients with arginine vasopressin deficiency (central diabetes insipidus): a single-centre, case-control study with nested, randomised, double-blind, placebo-controlled crossover trial. (unibas.ch)
  • BPA Changes Gene Expression in the brain effecting oxytocin/vasopressin, elevating Anxiety: Soy may mitigate it. (clinicalnews.org)
  • Both are required for oxytocin release, thus changes in oxytocin/vasopressin signaling pathways may underpin the behavioral changes. (clinicalnews.org)
  • Lysine vasopressin, the selective V2 agonist dDAVP, and the V1-selective agonist SK&F 105349 were at least 10- to 100-fold less potent than oxytocin and exhibited only partial agonist activity. (aspetjournals.org)
  • Here, we conducted an exploratory, randomized, placebo-controlled, cross-over study to examine effects of intranasal OT in male patients suffering from chronic low back pain (CBP) versus healthy controls (HC). (iasp-pain.org)
  • Half of the participants were given measured doses of oxytocin, while the rest were offered a placebo. (psychcentral.com)
  • They attended two imagery sessions, receiving oxytocin in one and a placebo in the other. (derby.ac.uk)
  • Participants higher in self-criticism, lower in self-reassurance, social safeness, and attachment security had less positive experiences of CFI under oxytocin than placebo, indicating that the effects of oxytocin on affiliation may depend on attachment and self-evaluative styles. (derby.ac.uk)
  • In a double-blind, placebo-controlled design, 47 heterosexual couples (total n = 94) received oxytocin or placebo intranasally prior to instructed couple conflict. (edu.au)
  • To arrive at this conclusion, the researchers administered either an oxytocin nasal spray or a placebo to healthy, straight men. (smithsonianmag.com)
  • And importantly, committed men who were given the placebo did not insist on the same distance as those administered oxytocin, an indication that the hormone discourages partnered - but not single men - from getting too close to a female stranger. (smithsonianmag.com)
  • In either form, oxytocin stimulates uterine contractions to speed up the process of childbirth. (wikipedia.org)
  • For example, when oxytocin is released during a contraction of the uterus at the start of childbirth, this stimulates production and release of more oxytocin and an increase in the intensity and frequency of contractions. (wikipedia.org)
  • Oxytocin causes uterine contractions and will expel the pregnancy, right? (equine-reproduction.com)
  • Production and secretion of oxytocin is controlled by a positive feedback mechanism, where its initial release stimulates production and release of further oxytocin. (wikipedia.org)
  • Estrogen has been found to increase the secretion of oxytocin and to increase the expression of its receptor, the oxytocin receptor, in the brain. (wikipedia.org)
  • Therefore, we evaluated the effect of osmotic regulation of VP and OT release on ER-β expression in SON and PVN to provide insight into the physiological role of gonadal steroids in the regulation of VP and OT secretion. (jneurosci.org)
  • This test stimulates oxytocin secretion, i.e. the release of the hormone in the body. (unibas.ch)
  • The hypothesis for this effect is that the exogenous oxytocin inhibits the natural increase in endometrial oxytocin receptor concentration at the end of diestrus that normally leads to oxytocin-induced PGF2α secretion, which in turn would result in luteolysis [1] . (equine-reproduction.com)
  • The uterine-contracting properties of the principle that would later be named oxytocin were discovered by British pharmacologist Henry Hallett Dale in 1906, and its milk ejection property was described by Ott and Scott in 1910 and by Schafer and Mackenzie in 1911. (wikipedia.org)
  • The aim of the study was to evaluate the clinical efficacy of magnetic resonance-guided High-Intensity Focused Ultrasound (HIFU) in patients with symptomatic uterine fibroids (myomata) after application of oxytocin. (hindawi.com)
  • In women, a single dose of estradiol has been found to be sufficient to increase circulating oxytocin concentrations. (wikipedia.org)
  • This research aims to compare the hemodynamic effects of carbetocin and oxytocin throughout elective cesarean delivery under regional anesthesia in a double-blind, randomized controlled trial. (researchbib.com)
  • This provides strong evidence that their production of oxytocin is also impaired. (unibas.ch)
  • Adequate amounts of Oxytocin make people feel good, and it produces pleasant feelings using brain pathways that are very similar to the ones that opiates use (see the NCBI link below). (online-literature.com)
  • The only possible downside is that sex-workers might try to take advantage, but that is not a major problem, and pair bonding is encouraged by oxytocin, so people would tend to become involved in long term relationships when they get adequate amounts of oxytocin. (online-literature.com)
  • However, whereas oxytocin plasma concentrations peaked at 15 min after intranasal administration and decreased after 75 min, CSF concentrations took up to 75 min to reach a significant level. (nature.com)
  • Oxytocin is released into the bloodstream as a hormone in response to sexual activity and during labour. (wikipedia.org)
  • New research, however, suggests that oxytocin must be used carefully because too much oxytocin (in healthy young adults) can actually result in oversensitivity to the emotions of others. (psychcentral.com)
  • Previous research suggests that oxytocin is an anorectic with selective effects on sweet-tasting food. (kingston.ac.uk)
  • This suggests that oxytocin may help reduce the cognitive decline we see in Alzheimer's disease. (neurosciencenews.com)
  • Based largely on a number of short-term administration studies, growing evidence suggests that central oxytocin is important in the regulation of energy balance. (nih.gov)
  • Moreover, intranasally delivered OXT may cause some of its central effects by stimulating the endogenous OXT system, which secretes OXT into the peripheral circulation but also distributes it within the brain - via targeted synaptic/dendritic release as well as less targeted long-distance diffusion from hypothalamic release sites 2 . (nature.com)
  • Thus, oxytocin signaling likely mediates the effect of hypothalamic leptin on satiety circuits of the caudal brainstem. (jneurosci.org)
  • However, peptides like oxytocin are characterized by weak blood-brain barrier permeability, and so can only by efficiently delivered to the brain via intracerebroventricular (ICV) administration. (neurosciencenews.com)
  • But lately, the phone calls have been less about his research and more about media reports that have elevated the status of the oxytocin nasal spray his team devised to that of a truth serum, a trust drug -- even a love potion. (go.com)
  • And though the science lags behind, Yong writes, hyped coverage of the hormone spurs parents into rushing out to buy oxytocin nasal spray for their children with autism or depression. (smithsonianmag.com)
  • Oxytocin is derived by enzymatic splitting from the peptide precursor encoded by the human OXT gene. (wikipedia.org)
  • The oxytocin peptide is synthesized as an inactive precursor protein from the OXT gene. (wikipedia.org)
  • Oxytocin receptor gene DNA methylation : A biomarker of treatment response in obsessive-compulsive disorder? (edu.au)
  • The paper, " Anxiogenic effects of developmental Bisphenol A exposure 1 are associated with gene expression changes in the juvenile rat amygdala and mitigated by soy ," was published Sept. 5 in the journal PLOS ONE . (clinicalnews.org)
  • Effects of oxytocin pathway gene polymorphisms and adverse childhood experiences on emotion recognition in schizophrenia spectrum disorders]. (bvsalud.org)
  • To study a role of the interaction of oxytocin pathway gene polymorphisms and adverse childhood experiences (ACE) in facial emotion recognition (FER) deficits in schizophrenia . (bvsalud.org)
  • published this month in BMC Medicine , reports on genomic and epigenetic alterations of OXTR , the gene encoding the receptor for oxytocin. (biomedcentral.com)
  • They identified a genomic deletion containing the gene encoding for the oxytocin receptor ( OXTR ) in an autistic male individual and in his mother, who probably experienced obsessive-compulsive disorder (OCD). (biomedcentral.com)
  • Emerging and exciting areas of research and novel methodological approaches, including genome-wide gene expression studies, immune, endocannabinoid, oxytocin, and glutamatergic systems, are explored to help delineate innovative mechanisms that may contribute to resilience. (cdc.gov)
  • However, analgesic effects of OT in chronic pain conditions remain elusive and the neural underpinnings have not yet been investigated in humans. (iasp-pain.org)
  • There has been an unprecedented interest in the modulatory effects of intranasal oxytocin on human social cognition and behaviour, however as yet no study has actually demonstrated that this modality of administration increases concentrations of the peptide in the brain as well as blood in humans. (nature.com)
  • The human literature is therefore scanned thoroughly and different approaches to study the effects of OT on pain perception in humans are discussed. (nih.gov)
  • Although the majority of findings are based on the results of animal experiments, there are already a number of studies that indicate similar effects of oxytocin in humans. (oxytocin.wiki)
  • Oxytocin had already been called the "hormone of mother love" by people studying maternal behavior in animals and humans. (medscape.com)
  • have comparable hemodynamic effects (hypotension and tachycardia), and there was no statistically significant difference between the two drugs with the previous doses regarding MI symptoms, hypotensive effects, blood loss orHB difference levels pre and postoperative, and both drugs have the same good prophylactic effect from PPH. (researchbib.com)
  • A side effect is an unwanted response to a medication when it is taken in normal doses. (medbroadcast.com)
  • A little oxytocin seems to be good, but large doses can disrupt the process-especially the development of the baby. (medscape.com)
  • We conclude that in LLC-PK1 cells, oxytocin stimulates a transient rise in cytosolic free [Ca2+]i and the formation of inositol phosphates, including Ins1,4,5P3. (aspetjournals.org)
  • The possible benefits from pharmacotherapy must be balanced against the likely adverse effects on a case-by-case basis. (medscape.com)
  • NSAIDs such as mefenamic acid have a number of adverse effects (digestive disorders, diarrhoea, haemolytic anaemia and seizures) [7]. (who.int)
  • Adverse effects are minimal and regimens are cost effective. (medscape.com)
  • The Committee reviewed the available evidence on analogue insulins compared to recombinant human insulin and concluded that analogue insulins currently offer no significant clinical advantage over recombinant human insulin and there is still concern about possible long-term adverse effects. (who.int)
  • The oxytocin receptor is found in various tissues in the human body, including in a woman's breast and uterus, and in both male and female testicles. (naturaltherapypages.com.au)
  • Studies on the isolated mouse uterus have demonstrated an antispasmodic effect of fennel on spasms induced by oxytocin and prostaglandin E2 [4]. (who.int)
  • Moreover, because testosterone (T) can be aromatized into estrogen in the hypothalamus ( Lephart, 1996 ) and because the androgen receptor is not expressed in MNCs, it is conceivable that effects of T could also be mediated through ER-β. (jneurosci.org)
  • Produced by the hypothalamus and released by the pituitary gland, oxytocin is associated with social bonding, trust and emotional wellbeing. (naturaltherapypages.com.au)
  • The nine-amino acid peptide oxytocin is synthesised mainly in the hypothalamus and secreted directly into the brain but also released via the posterior pituitary gland to regulate a range of physiologic and metabolic eating processes. (kingston.ac.uk)
  • This oxytocin receptor provides oxytocin's action within these tissues. (naturaltherapypages.com.au)
  • The final experiment provided evidence that oxytocin increases social modelling of food intake, which is consistent with previous research into oxytocin's social effects. (kingston.ac.uk)
  • Researchers' understanding of the complex physiological and social drivers behind oxytocin's regulation and effects on individuals remains minimal. (smithsonianmag.com)
  • An intranasally delivered oxytocin derivative helped improve cognitive function and reduced cognitive impairment in mouse models of Alzheimer's disease. (neurosciencenews.com)
  • It is intriguing to examine whether oxytocin modulates plastic changes in body representation, such as the changes occurring in the RHI. (frontiersin.org)
  • There is evidence that oxytocin modulates attention from food to social stimuli in females with anorexia but, to date, this has not been researched in people without eating disorders. (kingston.ac.uk)
  • To assess how oxytocin modulates attention in healthy adults not reporting disordered eating, a dot-probe test with food and neutral pictures was carried out. (kingston.ac.uk)
  • The main signaling pathway is the Gq/PLC/Ins3 pathway, but the MAPK and the RhoA/Rho kinase pathways are also activated, contributing to increased prostaglandin production and direct contractile effect on myometrial cells. (genome.jp)
  • There continues to be a considerable need for research into oxytocin in order to better understand the physiological and pathophysiological actions and to be able to derive possible therapeutic uses. (oxytocin.wiki)
  • The psychological and physiological effects of MDMA on normal voluntee. (erowid.org)
  • Acute psychological and physiological effects of MDMA ('Ecstasy') afte. (erowid.org)
  • It has been shown previously that treatment of mares with oxytocin at certain levels and points in diestrus can maintain the corpus luteum beyond the stage where it would normally be lysed (functionally destroyed) by the naturally-occurring prostaglandin release towards the end of diestrus. (equine-reproduction.com)
  • Nonperfused volume was statistically significantly larger in oxytocin group than in control group (p=0.0019). (hindawi.com)
  • Oxytocin significantly reduced sAA during couple conflict in women, whereas men showed increases in sAA levels (sex × group interaction: B = −49.36, t = −2.68, P = 0.009). (edu.au)
  • Results: We found the level of oxytocin in CSF to be significantly lower by 33.5% in HDGECs compared to controls (p = 0.016). (lu.se)
  • When dividing the HDGECs into groups with or without cognitive impairment, we found the oxytocin level to be significantly lower by 30.3% in the HDGECs with cognitive symptoms (p = 0.046). (lu.se)
  • We find that HDGECs have a significantly lower level of oxytocin compared to controls, and that the level of oxytocin may represent an objective and comparable measure that could be used as a state biomarker for impairment of social cognition. (lu.se)
  • In the present study, we investigated the relationship between salivary oxytocin concentration and the feeling of rubber hand ownership. (frontiersin.org)
  • Salivary oxytocin was measured before and after the behavioral tasks. (frontiersin.org)
  • We found that participants who had high concentrations of salivary oxytocin tended to feel strong ownership of the rubber hand. (frontiersin.org)
  • 0.0001) from endometrial explants challenged with oxytocin or LPS compared with controls despite which fatty acid was added. (arizona.edu)
  • In the early 1950s, American biochemist Vincent du Vigneaud found that oxytocin is made up of nine amino acids, and he identified its amino acid sequence, the first polypeptide hormone to be sequenced. (wikipedia.org)
  • The oxytocin peptide is composed of nine amino acids and has a molecular weight of 1007 daltons (Da). (naturaltherapypages.com.au)
  • 0.10) between oxytocin plasma and CSF concentrations. (nature.com)
  • Many of the same tissues (e.g. ovaries, testes, eyes, adrenals, placenta, thymus, pancreas) where PAM (and oxytocin by default) is found are also known to store higher concentrations of vitamin C. Oxytocin is known to be metabolized by the oxytocinase, leucyl/cystinyl aminopeptidase. (wikipedia.org)
  • It probably reaches the mother's brain, and in our animal models we know that it has lifelong effects on the baby. (medscape.com)
  • Using peptide analogs, a poor correlation was found between antagonism of oxytocin-induced calcium transients of LLC-PK1 cells and pig kidney V2 and rat liver V1 receptor affinity. (aspetjournals.org)
  • Today at the Endocrine Society Annual Meeting , I talked about the epigenetic effects of oxytocin. (medscape.com)
  • mefloquine increases toxicity of oxytocin by QTc interval. (medscape.com)
  • misoprostol increases effects of oxytocin by pharmacodynamic synergism. (medscape.com)
  • oxytocin increases effects of dexfenfluramine by pharmacodynamic synergism. (medscape.com)
  • oxytocin increases effects of dexmethylphenidate by pharmacodynamic synergism. (medscape.com)
  • oxytocin increases effects of isoproterenol by pharmacodynamic synergism. (medscape.com)
  • Further studies on neuronal OT effects in larger samples of chronic back pain patients are needed to understand probable mechanisms of OT effects in chronic pain. (iasp-pain.org)
  • Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4. (erowid.org)
  • This provides an anatomical substrate for the effect of leptin on meal size, and more generally, a mechanism for how the brain controls short-term food intake as a function of the energetic stores available in the organism to maintain energy homeostasis. (jneurosci.org)
  • The influence of oxytocin on palatable food intake not initiated by deprivation-induced hunger has not yet been investigated. (kingston.ac.uk)
  • In the group experiment, 24 IU of intranasal oxytocin facilitated increased self-reported sociality and social modelling of food intake, but there was no overall anorectic effect of the peptide on eating. (kingston.ac.uk)
  • Similarly, meditation and mindfulness practices have been linked to increased oxytocin, enhancing emotional resilience and improving the mind-body connection. (naturaltherapypages.com.au)
  • Certain scents, like lavender or chamomile, have been found to have a calming effect, elevating mood and supporting emotional healing. (naturaltherapypages.com.au)
  • Understanding the significance of oxytocin in natural therapy can help individuals harness its benefits to foster emotional wellbeing, social connection and overall healing. (naturaltherapypages.com.au)
  • The mind-body connection is a fundamental aspect of natural therapy, and oxytocin plays a key role in nurturing emotional healing. (naturaltherapypages.com.au)
  • In natural therapy, various approaches can help stimulate oxytocin release and support emotional healing. (naturaltherapypages.com.au)
  • Mindfulness practices, such as meditation and yoga, encourage a state of present-moment awareness and can enhance oxytocin levels, thereby improving emotional wellbeing. (naturaltherapypages.com.au)
  • Beyond its role in social bonding and emotional healing, oxytocin has been found to have analgesic properties, making it relevant in pain management through natural therapies. (naturaltherapypages.com.au)
  • As expected, the test subjects who had taken oxytocin saw greater emotional intensity in the faces they were rating. (psychcentral.com)
  • In addition, the results contribute to a deeper understanding of oxytocin as a key hormone for socio-emotional effects. (unibas.ch)
  • Oxytocin primarily causes psychological effects, such as increased emotional attachment and sexual arousal. (healthline.com)
  • In fed females, 24 IU of intranasal oxytocin inhibited only sweet-snack intake but with a similarly large effect of 57%, but had no effect on taste ratings or cortisol, suggesting that reductions in snack eating may not be mediated by cortisol. (kingston.ac.uk)
  • This thesis also shows, for the first time, the anorectic capacity of oxytocin in females, and its independence from cortisol levels. (kingston.ac.uk)
  • These results suggest that the effects of this procedure reach beyond simple multisensory integration in the brain. (frontiersin.org)
  • Here, we review recent advances in animal research on the analgesic effects of OT and discuss possible target sites of OT within descending and ascending pain pathways in the brain. (nih.gov)
  • According to the current state of knowledge, oxytocin appears to be involved in functions in the following organs: male and non-pregnant female reproductive tract, pancreas, cardiovascular system, kidney, brain and breast. (oxytocin.wiki)
  • Opioids have a particular effect on your brain. (psychcentral.com)
  • Oxytocin is also secreted from the brain and a few other tissues, including the testes and ovaries. (researchbib.com)
  • We wanted to see if PAS-CPPs-oxytocin could be delivered more efficiently to the mouse brain for clinical application, and if it improved cognitive functional behavior in mice," states Prof. Oka. (neurosciencenews.com)
  • Finally, the distribution of the IN-administered oxytocin derivative in brain tissue was profiled by imaging of a fluorescent-tagged oxytocin derivative. (neurosciencenews.com)
  • The tagged PAS-CPPs-oxytocin showed distribution throughout the mouse brain following its IN administration. (neurosciencenews.com)
  • Prof. Oka explains the broader implications of their work, "The oxytocin derivative enters the brain more efficiently. (neurosciencenews.com)
  • [ 2 , 3 ] It is used to induce labor and to facilitate other processes, but without taking into account the fact that oxytocin reaches the brain. (medscape.com)
  • Oxytocin (OXT) is involved in the regulation of emotion, social cognition and metabolism, and our previous work showed that the OXT system is affected early in HD. (lu.se)
  • Recent studies have shown that oxytocin may modulate social recognition in both sexes, and thus it may be related to empathy. (frontiersin.org)
  • In addition to reduced stress, other benefits associated with increased oxytocin production include lower blood pressure, higher empathy with others and better social behaviour. (naturaltherapypages.com.au)
  • As a result, some doctors prescribe oxytocin off-label, to treat mild social unease in patients who don't suffer from a diagnosed disorder. (psychcentral.com)
  • The dot probe also assessed the effects of oxytocin on romantic and social images as these domains are also influenced by oxytocin. (kingston.ac.uk)
  • However, oxytocin did not affect reaction times to romantic or social stimuli, suggesting that effects were food specific. (kingston.ac.uk)
  • The dot-probe experiment of this thesis provides important evidence that oxytocin reduces attentional bias to food across a range of body mass indexes but does not alter the attention paid to romantic or social stimuli. (kingston.ac.uk)
  • Oxytocin also influences cardiovascular regulation and various social behaviors. (genome.jp)
  • As expected, the increase in oxytocin in the healthy individuals after a dose of MDMA caused pro-social behavior and an increase in empathy, combined with a reduction in anxiety symptoms. (unibas.ch)
  • Oxytocin is released because of exercise and intimate physical or social interactions with other people. (healthline.com)
  • Oxytocin is a hormone and neurotransmitter that has been linked to social behavior. (clinicalnews.org)
  • The results are consistent with the notion of the A (rs53576) allele 's role in sensitivity to childhood experiences that influence the psychosocial development and can be used in further studies of the oxytocin treatment of social cognition and social adaptation of patients with schizophrenia . (bvsalud.org)
  • stuff and you will a video one documented scientific results regarding oxytocin effects for the social knowledge and conclusion (Methods). (nccu.edu.tw)
  • We suggest treatment trials to evaluate a potential effect of oxytocin on social cognition in HD. (lu.se)
  • Misoprostol may augment the effects oxytocic agents, especially when given less than 4 hours before initiating oxytocin. (medscape.com)
  • While the ICV administration of native oxytocin improved test outcomes in both the Y-maze and MWM tests, the IN administered PAS-CPPs-oxytocin yielded memory improving effects in the Y-maze test. (neurosciencenews.com)