4,7-10 Based on this research, we know that early cochlear implantation within this sensitive period (best by age 1) leads to more normal brain development and yields more optimal listening and spoken language outcomes compared to late cochlear implantation. (hearingreview.com)
Measure of cochlear2
This so-called cochlear microphonic is still used today as a measure of cochlear function. (wikipedia.org)
End points measured were electrophysiological, namely, compound action potential (CAP) an cochlear microphonic (CM). CAP is a measure of cochlear output generated at the inner hair cell-type I spiral ganglion synapse, and , CM is generated largely by the outer hair cell. (cdc.gov)
Compound action potential3
Interactions with noise on cochlear potentials, namely compound action potential (CAP) and cochlear microphonic (CM) were studied. (cdc.gov)
Sound-evoked (compound action potential, summating potential, cochlear microphonic) and spontaneous cochlear responses were recorded before and after perfusion. (edu.au)
ECochG generally involves measurement of the stimulus-related cochlear potentials (as opposed to the resting potentials), and often includes measurement of the whole nerve or compound action potential (AP) of the auditory nerve. (audiologyonline.com)
Responses11
While the function of the lateral efferent system in the cochlea is still unknown, previous studies have identified both excitatory and inhibitory changes in sound-evoked and spontaneous cochlear responses attributable to the lateral efferent system. (edu.au)
The first experiments in this thesis were designed to determine if activation or blockade of different dopamine receptor subtypes in the cochlea could lead to both excitatory and inhibitory changes in sound-evoked and spontaneous cochlear responses. (edu.au)
Therefore, we attempted to investigate the effects of putative dopamine depletion of the cochlea and found that application of the dopaminergic neurotoxin MPTP causes changes in both neural and hair cell responses which have not been reported before. (edu.au)
The role of the medial olivocochlear (MOC) reflex has been investigated by assessing changes of cochlear responses (CR) in humans. (missouristate.edu)
Audiological evaluation revealed mixed hearing loss and signs of auditory neuropathy spectrum disorder (ANSD) despite absence of otoacoustic emissions and an absent click-evoked auditory brainstem response (ABR) without recording of cochlear microphonics (CM). ANSD was characterized by abnormal speech discrimination, bilateral robust CM to 2,000 Hz tone-burst (TB) ABR, and abnormal left thalamocortical and cortical pathways diagnosed based on auditory middle latency and cortical N1-P2 responses. (ejao.org)
Although individual responses to cochlear implants are highly variable and depend on a number of physical and psychosocial factors, the trend toward improved performance with increasingly sophisticated electrodes and programming strategies has dramatically expanded indications for cochlear implantation. (medscape.com)
In addition to ASSRs, envelope-following response (EFR) recordings designed to distinguish peripheral (cochlear nerve) from central (brainstem) were recorded to document the effect of brainstem dysfunction on the two types of phase-locked responses. (bvsalud.org)
CONCLUSIONS: The present study, performed on 3 sleeping children with severe brainstem dysfunction but normal cochlear responses (cochlear microphonic potential, summating potential, and ABR wave I), revealed the differential sensitivity of three auditory electrophysiological techniques. (bvsalud.org)
EFR recordings (cases posterior fossa tumor and UD) showed preserved central responses with abnormal latencies and low phase-locking values, whereas the peripheral EFR attributed to the cochlear nerve was normal. (bvsalud.org)
Adding separate R and C responses (middle tracing) enhances the cochlear Summating Potential (SP) and auditory nerve Action Potential (AP). (audiologyonline.com)
Subtracting R and C responses (bottom tracing), enhances the Cochlear Microphonic (CM) (from ASHA, 1988, pg. (audiologyonline.com)
Implantation2
Because preoperative expectations affect the patient's postoperative satisfaction and use of the implant, all patients and families require attention and counseling from an implant team before they embark on the life-changing journey of cochlear implantation. (medscape.com)
The HINT measures word-recognition abilities to evaluate the patient's candidacy for cochlear implantation, in conjunction with conventional pure-tone and speech audiometry. (medscape.com)
Cortical4
The findings in this study support the use of TB ABR and auditory cortical potentials in the ANSD test protocol and in patients with craniofacial anomalies. (ejao.org)
With a better understanding of cortical brain changes associated with hearing loss, the potential to develop objective brain-based tools (ie, biomarkers) increases. (hearingreview.com)
That is, we can examine the function of higher auditory centers of the brain (eg, auditory cortex) using cortical auditory evoked potentials (CAEPs). (hearingreview.com)
The cortical auditory evoked potential (CAEP) response is comprised of three parts: the P1, N1, and P2. (hearingreview.com)
Implants2
[ 6 ] However, many candidates for cochlear implants do not have access to this procedure, due to failure to recognize appropriate candidates or because of inadequate healthcare resources. (medscape.com)
In this review, we will discuss how CAEPs can be used to assess development of the auditory cortex and monitor the maturation of the auditory cortex and central auditory pathways before and after intervention with hearing aids and cochlear implants. (hearingreview.com)
Brainstem3
RESULTS: The brainstem dysfunctions of the 3 children were revealed as abnormal (weak, absent, or delayed) ABRs central waves with a normal wave I. In addition, they all presented a summating and cochlear microphonic potential in their ABRs, coupled with a normal wave I, which implies normal cochlear and cochlear nerve function. (bvsalud.org)
Although available to the hearing scientist/clinician for over 50 years, ECochG's emergence as a clinical tool (as well as all other auditory evoked potentials) was rekindled in part by the discovery, application and popularity of the auditory brainstem response (ABR). (audiologyonline.com)
We investigated 20 students from a Center for Diagnosis and Rehabilitation, with no hearing impairment, all female aged 15-30 years old, who were screened for brainstem auditory evoked potential, which presented stimuli in different polarities ranges, including condensation and rarefaction in different presentation rates of 21.7, 27.7 and 47.7 stimuli per second. (bvsalud.org)
Cochlea2
As the term implies, 'Electrocochleography' (ECochG) is a method for recording the electrical potentials of the cochlea. (audiologyonline.com)
For example, how do the 3000 rows of active outer hair cells interact with each other and with other cochlear structures to amplify the waves in the cochlea that allow us to hear? (southampton.ac.uk)
Neural2
The CR consists of pre-neural and neural potentials originating from the inner ear, and at high signal levels is dominated by cochlear microphonic (CM). The CM originates from the outer hair cells, where the MOC fibers synapse, and there is little research about using it to investigate the MOC reflex in humans. (missouristate.edu)
An abnormal left thalamocortical auditory pathway may be attributable to the combined effect of lack of neural synchrony secondary to ANSD mainly on the left and/or brain injury. (ejao.org)
Pathways1
These seven waves, and the cochlear nucleus and between these the top five most interest and, among them, the pathways exists a series of parallel pathways7. (bvsalud.org)
Stimulus1
These findings indicate the MOC effect is measurable when using a low frequency stimulus, but not high frequency. (missouristate.edu)
Outer2
The suppression of the cochlear microphonic suggests that dopamine receptor influence is not confined to the primary afferent dendrite may also include the active process of the outer hair cells. (edu.au)
Previously, the phase effect mechanism was proposed to be dominantly contributed by peripheral auditory function,mainly by outer hair cells. (iium.edu.my)
Action potential1
Although Wever and Bray misinterpreted the signal as the action potential of the auditory nerve, the effect was real. (wikipedia.org)
Clinical3
The technical capability of recording cochlear and auditory nerve potentials in humansled to a variety of clinical applications for ECochG. (audiologyonline.com)
The long term research goal is to understand human cochlear physiology in both normal and pathological conditions with a view to aiding the development of improved clinical diagnostic techniques and treatments. (southampton.ac.uk)
The ways in which these models may be useful clinically are: to aid the development of treatments, or prostheses for hearing impairment, to improve our ability to interpret clinical results (such as measurements of otoacoustic emissions or electrophysiology), to aid the development of new clinical tests of cochlear function. (southampton.ac.uk)
Peripheral1
gem homozygous receptor mutant HCs display normal cell viability, afferent synaptogenesis, and peripheral innervation, yet exhibit strongly reduced extracellular potentials (∼50% of wild-type potentials). (jneurosci.org)
ECochG3
Pearson and Spearman analysis were performed to find correlation between phase effect and individual ECochG components' amplitude. (iium.edu.my)
Results: Result showed no significant correlation between phase effect and all ECochG components' amplitude at all tested frequencies with exception at 2 kHz. (iium.edu.my)
As indicated in the preceding section, the potentials most often recorded via ECochG include the CM, SP and AP. (audiologyonline.com)
Waves1
Waves I and II are addition, in the computer some characteristics that generated in the cochlear nerve and subsequent define certain acquisition parameters record the 1 Speech-Language Therapist. (bvsalud.org)
Contralateral2
Human Medial Olivocochlear Reflex: Contralateral Activation Effect on " by Abdullah M. Jamos, Wafaa A. Kaf et al. (missouristate.edu)
The current study aimed to investigate the effect of contralateral activation of the MOC reflex on the CR in humans. (missouristate.edu)
Function4
This study aims to investigate the possible involvement of central auditory function (i.e. auditory nerve) in the phase effect mechanism. (iium.edu.my)
Conclusions: This finding suggests that central auditory function (i.e. auditory nerve) is possibly involved in the phase effect mechanism. (iium.edu.my)
The reader is urged to review this literature to gain a better understanding and appreciation of the specific features of these potentials and their relevance to hearing function. (audiologyonline.com)
As a profession, we're just beginning to unearth the widespread central effects of hearing loss, including its effect on cognitive function, listening effort, and social-emotional changes. (hearingreview.com)
Hearing aids1
For patients with hearing loss that is not mitigated by hearing aids, a cochlear implant may provide an opportunity for hearing. (medscape.com)
Normal2
The EFR-Hs onset latencies, response durations, and phase-locking values did not differ from their respective age-matched control values, indicating normal cochlear nerve EFRs. (bvsalud.org)
The entirely normal EFR-H recordings observed in two cases further strengthen the hypothesis of its cochlear nerve origin in sleeping children. (bvsalud.org)
Humans2
Moreover, the CR could be used as a potential tool to study the MOC reflex in humans. (missouristate.edu)
The reader is referred to Ferraro (2000) for a more thorough review of the history of these potentials as recorded in humans. (audiologyonline.com)
Children1
As hearing care professionals-whether our jobs involve activating a cochlear implant, fitting a hearing aid, or providing rehabilitation to adults or children to help them reach their optimum performance after intervention-neuroplasticity is at the heart of what we do. (hearingreview.com)
Central1
One of the neurotransmitters in the lateral efferents is the catecholamine dopamine, which in the central nervous system is known to exert inhibitory and excitatory effects by activating different receptor subtypes. (edu.au)
Electrical3
The cochlear implant is a surgically placed device that converts sound to an electrical signal. (medscape.com)
This electrical signal is transmitted via electrodes to the spiral ganglion cells in the cochlear modiolus. (medscape.com)
These should capture the essential hydrodynamics, structural dynamics, and electrical processes involved in cochlear physiology. (southampton.ac.uk)
Response1
These potentials were recorded in response to pure tomes between 2 and 40 kHz NIHL was found to comply with the principle of equal energy. (cdc.gov)
Noise2
Effects of exposure duration on potentiation of noise induced hearing loss by carbon monoxide. (cdc.gov)
In determining cochlear implant candidacy, the HINT is performed without background noise, despite its name. (medscape.com)
Study1
In this study, adult male Long Evans hooded rats were used to examine the effects of potassium cyanide (KCN). (cdc.gov)
Test1
Schroeder-phase masking test was conducted at 500 Hz, 1 kHz, and 2 kHz (75 dB A), and phase effect was recorded. (iium.edu.my)
Patients2
About 736,900 registered cochlear implant devices had, as of December 2019, been placed in patients worldwide. (medscape.com)
Aran and LeBert, 1968) performed their measurements on patients undergoing middle ear surgery and/or used a non-surgical approach that involved passing a needle electrode through the tympanic membrane (TM) to rest on the cochlear promontory. (audiologyonline.com)