ChlorideExposureArsenicMercuryToxicityKidneysPesticidesHigh levels of cadmiumOxideConcentrationsSulfideAmount of cadmium in bloodAcuteCarcinogenicityLarge amounts of cadmiumCarcinogenMetalsLead and cadmiumNickel-cadmium bInorganic compoundUrinarySubstancesStearateAdverse effectsCdClZincExposuresChronicGenotoxicityChemicalOccursChemicalsOxidative stressHumansChromiumMortalityEnters the environmentNauseaStabilizersCopperDoseConcentrationMetalFragile bonesCytotoxicitySoilsHazardousDosesEnvironmental ProtecEarth'sReproductiveBirth defectsChlorine1998Cigarette smoke
Chloride12
- Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride. (cdc.gov)
- Exposure of human cell lines, HCT15, PLC/PR/5, HeLa, and Chang, to cadmium chloride resulted in cytotoxicity and cell death, and this was associated with a significant decrease in eIF4E protein levels. (cdc.gov)
- Taken together, our results demonstrate that the exposure of cells to cadmium chloride resulted in cytotoxicity and cell death due to enhanced ubiquitination and consequent proteolysis of eIF4E protein, which in turn diminished cellular levels of critical genes such as cyclin D1. (cdc.gov)
- Cadmium compounds are used in the metal plating and battery industry, and as stabilizing agents in many polyvinyl chloride (PVC) products. (dcceew.gov.au)
- Cadmium chloride is used in the dyeing and printing of fabrics, in electronics component manufacture and in photography. (dcceew.gov.au)
- Cadmium is most often found combined with other elements, which produces compounds such as Cadmium chloride, Cadmium oxide, and Cadmium sulfite. (dcceew.gov.au)
- In water some of the compounds will be quite soluble (cadmium chloride) and others will be insoluble (cadmium oxide). (dcceew.gov.au)
- It is usually found as a mineral combined with other elements such as oxygen (cadmium oxide), chlorine (cadmium chloride), or sulfur (cadmium sulfate, cadmium sulfide). (cdc.gov)
- When administered orally , the water soluble cadmium chloride caused mortality at relatively low doses, with LD50s in mouse and rat ranging from 29 to 327 mg Cd/kg bw. (europa.eu)
- R25, which is justified given its comparable solubility to cadmium chloride. (europa.eu)
- Cadmium chloride and oxidehave a high acute toxicity by the inhalation route. (europa.eu)
- The aim of the study was - to compare the content of micro and macro elements in the liver and kidneys of experimental animals after exposure to cadmium sulfide NP and cadmium chloride. (ujoh.org)
Exposure48
- In addition, exposure of cells to cadmium resulted in enhanced ubiquitination of eIF4E protein while inhibitors of proteasome activity reversed the cadmium -induced decrease of eIF4E protein. (cdc.gov)
- Exposure of cells to cadmium , as well as the specific silencing of eIF4E gene, also resulted in decreased cellular levels of cyclin D1, a critical cell cycle and growth regulating gene, suggesting that the observed inhibition of cyclin D1 gene expression in the cadmium -treated cells is most likely due to decreased cellular level of eIF4E. (cdc.gov)
- Cadmium Toxicity: What Health Effects Are Associated With Acute High-Dose Cadmium Exposure? (cdc.gov)
- describe the health effects of acute high-dose cadmium exposure. (cdc.gov)
- In contrast, patients who have more intense exposure to cadmium and do not improve after one to two days may progress in eight hours to seven days to acute chemical pneumonitis and pulmonary edema. (cdc.gov)
- Aetna considers laboratory testing medically necessary for heavy metal poisoning (e.g., arsenic, cadmium, copper, gold, iron, mercury) for members with specific signs and symptoms of heavy metal toxicity and/or a history of likely exposure to heavy metals. (aetna.com)
- Workers in the industries that use or produce cadmium and or cadmium compounds are at risk of exposure. (dcceew.gov.au)
- Consumers can be exposed to cadmium and or cadmium compounds by exposure to air from production and processing facilities using cadmium and or cadmium compounds. (dcceew.gov.au)
- The most significant route of exposure to cadmium and or cadmium compounds for most members of the general public is through food, since food materials tend to take up and retain cadmium. (dcceew.gov.au)
- Exposure to low levels of cadmium in air, food, water, and particularly in tobacco smoke over time may build up cadmium in the kidneys and cause kidney disease and fragile bones. (cdc.gov)
- In the Fourth National Report on Human Exposure to Environmental Chemicals (Fourth Report) , CDC scientists measured cadmium in the blood of 8,372 participants aged one year and older and in the urine of 2543 participants aged six years and older who took part in the National Health and Nutrition Examination Survey (NHANES) during 2003-2004. (cdc.gov)
- Biomonitoring data can also help scientists plan and conduct research on exposure and health effects. (cdc.gov)
- The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. (cdc.gov)
- Exposure to cadmium happens mostly in the workplace where cadmium products are made. (cdc.gov)
- Long-term exposure to lower levels of cadmium in air, food, or water leads to a buildup of cadmium in the kidneys and possible kidney disease. (cdc.gov)
- The health effects in children are expected to be similar to the effects seen in adults (kidney, lung, and bone damage depending on the route of exposure). (cdc.gov)
- Animal studies also indicate that the young are more susceptible than adults to a loss of bone and decreased bone strength from exposure to cadmium. (cdc.gov)
- How can families reduce the risk of exposure to cadmium? (cdc.gov)
- The amount of cadmium in your blood shows your recent exposure to cadmium. (cdc.gov)
- The amount of cadmium in your urine shows both your recent and your past exposure. (cdc.gov)
- Nongenotoxic mechanisms upregulating intracellular signalling pathways leading to increased mitogenesis are discussed as major mechanisms for the interpretation of the carcinogenic activity by chronic cadmium exposure. (nih.gov)
- No information was located regarding effects in humans after dermal exposure to cadmium. (europa.eu)
- In the present study, we investigated the effects of Cd exposure on microbiota and serum metabolism in rats by omics analysis. (frontiersin.org)
- A study reported in The Lancet found that the "daily exposure of infants to isoflavones in soy infant-formulas is 6-11 fold higher on a bodyweight basis than the dose that has hormonal effects in adults consuming soy foods. (westonaprice.org)
- Amelioration the toxic effects of cadmium exposure in nileTilapia (Oreochromi. (calgarysundevilsbasketball.ca)
- Important considerations in evaluating the effects of secondhand smoke include the magnitude of exposure to it, 1 how exposure can be measured, and how exposure changes with the implementation of smoking bans. (nationalacademies.org)
- Occupational exposure to cadmium and cadmium compounds occurs mainly in the form of airborne dust and fume. (inchem.org)
- Urinary and blood cadmium concentrations are generally much lower in non-occupationally exposed people, for whom the most important sources of exposure are cigarette smoking and, especially in polluted areas, eating certain foods (e.g. rice). (inchem.org)
- A case-control analysis of lung cancer did not show any association with exposure to cadmium. (inchem.org)
- Excess mortality from lung cancer was reported among workers employed in a US cadmium recovery plant, and a dose-response relationship was demonstrated between estimated cumulative exposure to cadmium and lung cancer risk. (inchem.org)
- In a large cohort of workers from 17 cadmium processing plants in the United Kingdom, decreased mortality from prostatic cancer was observed, while that from lung cancer was increased in the overall cohort and there were suggested trends with duration of employment and with intensity of exposure. (inchem.org)
- The increase in lung cancer risk was stronger in the small proportion of workers with high cadmium exposure. (inchem.org)
- Excess mortality from stomach cancer, which was not related to intensity of cadmium exposure, was also reported among these workers. (inchem.org)
- Constraints that influence the assessment of both lung and prostatic cancer risk are that the number of long-term, highly exposed workers is small, the historical data on exposure to cadmium are limited, particularly for the non-US plants, and the ability to define and examine a gradient of cumulative exposure varies across studies. (inchem.org)
- Cadmium (Cd) exposure is a risk factor for endothelial dysfunction and cardiovascular disease. (bvsalud.org)
- Toxic effects were evaluated after 30 injections (1,5 months), 60 injections (3,0 months) and in the post-exposure period (1,5 months after cessation of the exposure). (ujoh.org)
- In the liver of experimental animals the most intensive accumulation of cadmium was observed after exposure to CdCl 2 , especially in the post-exposure period. (ujoh.org)
- There was a higher content of cadmium after exposure to CdS NP-6 nm, as compare to CdS NP 9-11 nm. (ujoh.org)
- Significant accumulation of cadmium was recorded in the kidneys, especially in the post-exposure period, which can indicate an intensive elimination from the body. (ujoh.org)
- A significant accumulation of cadmium was recorded in the kidneys, especially in the post-exposure period, which can point to an intensive elimination from the body. (ujoh.org)
- The prolonged exposure to cadmium compounds also led to the increase of copper levels and decrease in iron and selenium levels in the kidneys. (ujoh.org)
- Determination of the content of cadmium, macro- and microelements in the inner organs allows assessing cadmium toxicokinetics in the body, predicting the pathogenetic features of its toxic effects, especially in the post-exposure period, as well as studying the peculiarities of the pathogenesis of its organotoxic action. (ujoh.org)
- 1998, "Health effects of cadmium exposure - a review of the literature and a risk estimate", Scandinavian Journal of Work, Environment & Health, v. 1, pp. 1-52. (ujoh.org)
- 2014, "Non-renal effects and the risk assessment of environmental cadmium exposure", Environmental Health Perspectives, v. 122 (5), р. (ujoh.org)
- However, the health assessor will find the information in this report useful in characterizing the significance of exposure pathways and the importance of the physical and chemical properties of the lead compounds that may impact on persons' uptake of lead. (cdc.gov)
- When evaluating whether a dose-dependent relationship was present, seventeen of the eighteen compounds led to greater DNA damage with increasing exposure concentrations. (cdc.gov)
- But do we know the levels at which they become toxic or the specific health effects of exposure? (cdc.gov)
- Health care professionals can search the Toxic Substances Portal for specific information about health effects caused by exposure to toxic substances. (cdc.gov)
Arsenic3
- Among the 17 prominent food contaminants identified by the World Health Organization (WHO), cadmium (Cd) occupies the third position, after aflatoxin and arsenic. (frontiersin.org)
- Alongside the three other heavy metals - arsenic, lead and mercury - cadmium appears in … 1.5 heavy metals toxicity (2).ppt - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online. (calgarysundevilsbasketball.ca)
- Cadmium is an important pollutant in the environment, toxic to most organisms and a potential threat to human health: Crops and other plants take up Cd from the soil or water and may enrich it … document will deal with mercury, lead, cadmium, tin and arsenic only. (calgarysundevilsbasketball.ca)
Mercury9
- A PC's central processing unit (CPU), the module containing the chip and the hard disk, typically contains toxic heavy metals such as mercury (in switches), lead (in solder on circuit boards), and cadmium (in batteries). (ghanabusinessnews.com)
- Lead, mercury, cadmium, and polybrominated flame retardants are all persistent, bio-accumulative toxins (PBTs), that can create environmental and health risks when computers are manufactured, incinerated, landfilled or melted during recycling. (ghanabusinessnews.com)
- The effect of phenobarbital on the biliary excretion of metals in rats was com-pared among methyl mercury, inorganic mercury and cadmium compounds from which phenobarbital prevented animals. (go.jp)
- In rats given an i.v. administration of 1mg/kg Cd or Hg, large amounts of cadmium (15.1% of the dose) were found in the bile within 5 hr after the dose, but small amounts of mercury were excreted with bile (1.4 and 3.3% in inorganic mercury and methyl mercury groups, respectively). (go.jp)
- Phenobarbital significantly increased the biliary excretion of methyl mercury and cadmium (154 and 140% of controls, respectively), but not that of inorganic mercury. (go.jp)
- Concentrations of methyl mercury in the bile also increased in the treated rats, but those of cadmium did not change when compared with controls. (go.jp)
- What about the toxic substances we hear about in the news-mercury in canned tuna, BPA in plastic, cadmium in jewelry? (cdc.gov)
- Similar changes develop in animals injected with heavy metals, such as cadmium, lead, and mercury. (medscape.com)
- Marine turtles of all species, particularly hawksbill turtles ( Figure 1 ), can contain a variety of toxins including heavy metals (e.g. cadmium and mercury), organic compounds (e.g. pesticides such as chlordane and polychlorinated biphenyls) and biotoxins such as those produced by various blue-green algae on which turtles feed (e.g. lyngbyatoxin A from Lyngbya majuscula ). (who.int)
Toxicity10
- Although original studies were not available, data for cadmium oxide and cadmium metal powder suggest that the slightly soluble or insoluble forms ofcadmium (like also cadmium hydroxide and cadmium carbonate) may present lower oral acute toxicity than the soluble cadmium compounds. (europa.eu)
- Cadmium nitrate, also highly water soluble, is at present not classified for acute oral toxicity but a similar classification should be considered. (europa.eu)
- Based on comparable toxicity and/or solubility / bioavailability, all other highly and slightly soluble cadmium forms, i.e. cadmium nitrate, hydroxide and carbonate should carry a comparable classification. (europa.eu)
- Also in view of the risk reduction measures which need to be taken as a result of the carcinogenicity of cadmium metal and some of the cadmium compounds, acute dermal toxicity is not likely to pose an issue for human health. (europa.eu)
- Both the liver and kidneys store cadmium as a metallothionein complex, which serves not only to transport cadmium but also acts as a defense mechanism against the toxicity of the unbound cadmium ion. (calgarysundevilsbasketball.ca)
- Cadmium toxicity in higher plants. (calgarysundevilsbasketball.ca)
- Cadmium toxicity occurs when high levels of the element are accumulated in the body, whether its through the ingestion of food or drink, inhalation o… Looks like you've clipped this slide to already. (calgarysundevilsbasketball.ca)
- Cadmium is a metallic element best known for its high toxicity and carcinogenicity. (calgarysundevilsbasketball.ca)
- 2006, "The toxicity of cadmium and resulting hazards for human health", Journal of Occupational Medicine and Toxicology, v. 1, рp. (ujoh.org)
- Genotoxicity of the compounds was determined using the comet assay, and toxicity determined via the cell viability assay. (cdc.gov)
Kidneys3
- Cadmium compounds are also toxic with a possible risk of irreversible effects on human health and accumulate in the human body, particularly the kidneys. (ghanabusinessnews.com)
- Cadmium damages the kidneys, lungs, and bones. (cdc.gov)
- The buildup of cadmium and its various compounds in human body may affect lungs, kidneys and reproductive organs and also may cause carcinogenic and teratogenic effects [ 3 ]. (jecst.org)
Pesticides3
- We also know they can attract and bind to compounds known to harm human health, such as cadmium, lead, PCBs and pesticides - beyond the toxic compounds used to make them. (signalscv.com)
- Chemical class - metals, pesticides and volatile organic compounds. (cdc.gov)
- The aim of this review was to present the main parameters used for the assessment of neurotoxicity during the initial period of life of rodents until puberty and to carry out a review of the most current literature on the toxic effects of pesticides, medications, licit and illicit drugs, toxins and environmental agents in rodent offspring. (bvsalud.org)
High levels of cadmium4
- Breathing high levels of cadmium damages people's lungs and can cause death. (cdc.gov)
- Breathing high levels of cadmium can severely damage the lungs. (cdc.gov)
- The babies of animals exposed to high levels of cadmium during pregnancy had changes in behavior and learning ability. (cdc.gov)
- From January to July this year, the CPSC issued recall orders targeting more than 200,000 "made-in-China" children's jewelry due to their high levels of cadmium, warning that "cadmium is toxic if ingested by young children and can cause adverse health effects. (motherearthphil.org)
Oxide5
- Cadmium iodide is prepared by the addition of cadmium metal, or its oxide, hydroxide or carbonate to hydroiodic acid. (wikipedia.org)
- Cadmium oxide is used in electroplating, in semiconductors, and in glass and ceramic glazes. (dcceew.gov.au)
- As fine powder cadmium metal will burn, releasing toxic fumes of cadmium oxide. (dcceew.gov.au)
- Inhalation of smoke from burning cadmium or from cadmium oxide is toxic to the respiratory system. (dcceew.gov.au)
- Among the important compounds of cadmium are cadmium oxide (used in batteries, as an intermediate and catalyst and in electroplating), cadmium sulfide (used as a pigment), cadmium sulfate (used as an intermediate and in electroplating) and cadmium stearate (used as a plastics stabilizer). (inchem.org)
Concentrations9
- People exposed to toxic air pollutants at sufficient concentrations and durations may have an increased chance of developing cancer or experiencing other serious health effects. (ny.gov)
- About 1 microM cadmium stimulates DNA synthesis and cell proliferation in various cell lines, whereas more elevated concentrations are inhibitory. (nih.gov)
- Cadmium enhances the expression of several classes of genes at concentrations of a few microM. (nih.gov)
- DBT and TBT revealed the most toxic effects even at low concentrations. (ontarioyoga.net)
- The effect on microbial parameters showed that the activity of certain soil microbial parameters can be inhibited or stimulated by the presence of LN at highest concentrations, probably by changing the pH of soil or by the intrinsic properties of LN. (up.pt)
- Predicted no-effect concentrations (PNEC) or hazard concentrations for 5% of the species (HC5) were also estimated based on the compilation of data available in the literature. (up.pt)
- Cadmium is found at low concentrations in the Earth's crust, mainly as the sulfide in zinc-containing mineral deposits. (inchem.org)
- Acidification of cadmium-containing soils and sediments may increase the concentrations of cadmium in surface waters and crops. (inchem.org)
- Safety and Health (OSHA) Act of 1970, 29 U.S.C. 669(a)(6) which authorizes the Secretary of Health and Human Services, following a written request from any employer or authorized representative of employees, to determine whether any substance normally found in the place of employment has potentially toxic effects in such concentrations as used or found. (cdc.gov)
Sulfide2
- Cadmium sulfide is used in the electronics industry for photocells and light emitting diodes. (dcceew.gov.au)
- 2014, "Genotoxicity and Cytotoxicity of Cadmium Sulfide Nanomaterials to Mice: Comparison Between Nanorods and Nanodots", Environmental Engineering Science, v. 31 (7), pp. 373- 380. (ujoh.org)
Amount of cadmium in blood1
Acute7
- The symptoms of acute cadmium inhalation can initially resemble classic metal fume fever, a self-limited condition associated with fever, chills and possible decreases in forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1). (cdc.gov)
- The most common way that acute poisoning via cadmium ingestion occurs is consumption of acidic food or beverages improperly stored in containers with a cadmium glaze (Lewis 1997). (cdc.gov)
- Recovery can occur from an acute episode of poisoning with no side effects. (cdc.gov)
- Acute inhalation of cadmium may cause symptoms similar to those of metal fume fever. (cdc.gov)
- When it accumulates in the environment, it has high acute and chronic effects on plants, animals and micro-organisms. (ghanabusinessnews.com)
- Acute cadmium poisoning is rare but gastrointestinal symptoms have been described after consuming food or drinks contaminated by cadmium from cooking utensils, solders in water pipes. (calgarysundevilsbasketball.ca)
- Urate oxidase (rasburicase), which catalyzes urate to a much more soluble compound, is usually given in acute urate nephropathy. (msdmanuals.com)
Carcinogenicity2
- establish mechanisms of action by studying the effects of the same chemicals in experimental animals and on human cells in vitro, allowing for a better prediction of human carcinogenicity and assessment of carcinogenic mechanisms. (who.int)
- A thorough investigation of its potential immunomodulatory effects may clarify its carcinogenicity potential. (who.int)
Large amounts of cadmium1
Carcinogen3
- Whether translation initiation factor 4E (eIF4E), the mRNA cap binding and rate-limiting factor required for translation, is a target for cytotoxicity and cell death induced by cadmium , a human carcinogen, was investigated. (cdc.gov)
- Chronic effects: Carcinogen, teratogen, and mutagen. (flinnsci.com)
- A GROUP campaigning for children's safety from harmful chemicals has called attention to the latest toxic scare sweeping across the U.S. today: cadmium, a known carcinogen, in children's jewelry. (motherearthphil.org)
Metals5
- Heavy metals, flame retardants, and plasticizers are among the prohibited compounds. (arenasolutions.com)
- These different effects of phenobarbital may reflect individual feature of in metabolism of three metals in the liver and those affinity to tissues. (go.jp)
- Most cadmium used in the United States is extracted during the production of other metals like zinc, lead, and copper. (cdc.gov)
- The two metals are persistent and some of their compounds accumulate in certain organisms. (faircompanies.com)
- The pollution caused by heavy metals and their impact on the environment has been increasing, with their effects extending to different environmental compartments such as water, soil, and atmosphere ( 1 , 2 ). (frontiersin.org)
Lead and cadmium2
- The European Commission recognizes that the majority of the lead and cadmium compounds, including those utilized in PVC, are toxic, harmful, dangerous to the environment and present a risk of accumulated effects. (faircompanies.com)
- When the lead and cadmium stabilizers in PVC remain contained in the use phase. (faircompanies.com)
Nickel-cadmium b2
- In the home, store substances that contain cadmium safely, and keep nickel-cadmium batteries out of reach of young children. (cdc.gov)
- Most of the cadmium produced today is obtained from zinc byproducts and recovered from spent nickel-cadmium batteries. (calgarysundevilsbasketball.ca)
Inorganic compound2
- Cadmium iodide is the inorganic compound with the formula CdI2. (wikipedia.org)
- Cadmium selenide (CdSe) is an inorganic compound that commonly crystallizes in either the hexagonal wurtzite or cubic zincblende structure. (refractiveindex.info)
Urinary2
Substances7
- This fact sheet is one in a series of summaries about hazardous substances and their health effects. (cdc.gov)
- Lead in the environment and its effects on the health of people is a matter of great concern to the Agency for Toxic Substances and Disease Registry (ATSDR). (cdc.gov)
- The Agency was established by the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA, also known as Superfund) to assess the public health impact of hazardous wastes in the general environment, to identify human populations at risk, and to effect actions to prevent adverse health effects from human contact with hazardous substances. (cdc.gov)
- 1, 2, 3, 4] The introduction of foreign substances into the skin can result in a number of adverse effects, including toxic or immunologic reactions to the tattoo pigments, transmission of infectious diseases, and the localization of skin disease within the tattoo. (medscape.com)
- So, in the fall of 2010, the Toxic Substances Portal was launched to provide an easy, user-friendly "one-stop shop" for anyone seeking information on the health effects of toxic substances. (cdc.gov)
- The Toxic Substances Portal features clean lines, text matched to graphics, and three featured sections with easy click access to a large amount of health effects information. (cdc.gov)
- Healthcare providers who can use free evidence-based medical education courses addressing the clinical health effects of hazardous substances. (cdc.gov)
Stearate1
- It has synergistic effect when used with metal soaps such as cadmium stearate, barium stearate or epoxy compounds. (unilongindustry.com)
Adverse effects6
- When not delivered properly, acupuncture can cause serious adverse effects, including infections, punctured organs, collapsed lungs, and injury to the central nervous system. (pulsus.com)
- The Food and Drug Administration (FDA) has reported an increasing number of adverse effects in EC users like chest pain, cough, shortness of breath, headache, nausea, dizziness. (theseoultimes.com)
- Severe Adverse Effects include hospitalization for illnesses like pneumonia, congestive heart failure, and seizure, second degree burns to the face (product exploded in user s mouth), and loss of vision requiring surgery. (theseoultimes.com)
- SAICM) that seeks to "prevent the adverse effects of chemicals on the health of children and other vulnerable groups and susceptible environments. (motherearthphil.org)
- Given the sensitivity of -omic analyses, low- dose adverse effects could also be observed and distinguished from high dose phenomena, and if exposures were accurately assessed, dose-response data could be incorporated into risk assessments. (who.int)
- Patients should be carefully monitored for adverse effects, including anaphylaxis and hemolysis. (msdmanuals.com)
CdCl2
- The study was conducted on mature male Wistar rats 160-180 g, intraperitoneally injected with CdS NP of 4-6 nm of 9-11 nm size as well as CdCl 2 in 0,08 mg/kg/day dose adjusted to cadmium. (ujoh.org)
- Along with the increase in the cadmium content in the liver, the growth of the content of copper, iron (more intensively with CdCl 2 ), iron, and lower selenium levels were recorded (especially for CdS NP 4-6 nm). (ujoh.org)
Zinc3
- The mechanisms underlying the modulation of gene activity by cadmium are discussed in terms of interference with cellular signalling at the levels of cell surface receptors, cellular calcium and zinc homeostases, protein phosphorylation, and modification of transcription factors. (nih.gov)
- Occupations in which the highest potential exposures occur include cadmium production and refining, nickel-cadmium battery manufacture, cadmium pigment manufacture and formulation, cadmium alloy production, mechanical plating, zinc smelting, soldering and polyvinylchloride compounding. (inchem.org)
- Cadmium is a precious and rare metal that coexists with the zinc ore in the nature and comes into being as a by-product in the manufacturing of zinc. (jecst.org)
Exposures1
Chronic2
- Chronic cadmium poisoning from the consumption of food occurred in the 1950s in cadmium-polluted areas in Japan. (calgarysundevilsbasketball.ca)
- The amount of interstitial connective tis- experimental data on chronic health effects been observed in hamsters that chronically sue in the lung also differs, with rats having of inhaled particles come from rats. (cdc.gov)
Genotoxicity2
- However, cadmium at noncytotoxic doses interferes with DNA repair processes and enhances the genotoxicity of directly acting mutagens. (nih.gov)
- In considering the available evidence, the carcinogenic properties of cadmium are interpreted using a multifactorial approach involving indirect genotoxicity (interference with DNA repair) and the upregulation of mitogenic signalling pathways. (nih.gov)
Chemical6
- bromides and chlorides of strongly polarising cations Hydroxides of dications, i.e. compounds with the general formula M(OH)2 Sulfides, selenides and tellurides (chalcogenides) of tetracations, i.e. compounds with the general formula MX2, where X = S, Se, Te NIOSH Pocket Guide to Chemical Hazards. (wikipedia.org)
- Learn more about chemical use in Toronto businesses, health effects, below. (toronto.ca)
- 1) The chemical symbol for cadmium is Cd and the atomic weight is 112.41 g/mol. (calgarysundevilsbasketball.ca)
- Resources (DENR) has yet to issue a chemical control order (CCO) that will regulate the use of cadmium and cadmium compounds. (motherearthphil.org)
- The Department of Environment and Natural Resources has issued the Chemical Control Order (CCO) for Chromium VI Compounds. (gov.ph)
- The Department of Environment and Natural Resources has issued the Chemical Control Order (CCO) for Cadmium and Cadmium Compounds. (gov.ph)
Occurs2
- Cadmium occurs in certain components such as SMD chip resistors, infra-red detectors, and semi-conductor chips. (ghanabusinessnews.com)
- Cadmium is a metallic element that occurs naturally in the Earth's crust. (calgarysundevilsbasketball.ca)
Chemicals1
- The EcoWaste Coalition, which recently asked the Aquino government to test toys for toxic chemicals as the Christmas season looms, revealed that the U.S. Consumer Product Safety Commission (CPSC) has so far issued five recall orders for cadmium-tainted children's jewelry from China, prompting policymakers to seek stringent standards. (motherearthphil.org)
Oxidative stress1
- They were particularly interested in measuring the change in Sirtuin1, an enzymatic protein (deacetylase), which is important for the survival of cells when they are exposed to oxidative stress, because Sirtuin1 increases the effect of certain antioxidants. (vitalraadet.dk)
Humans7
- Lead, which negative effects were recognized and therefore banned from gasoline in the 1970s causes damage to the central and peripheral nervous systems, blood systems, kidney and the reproductive system in humans. (ghanabusinessnews.com)
- In humans, the no observed effect level ( NOEL ) of a single oral dose is estimated to be equivalent to 3 mg Cd/person (i.e. 0.05 mg/kg bw for a 60 kg person) and the lethal dose is estimated to range from 350 to 8,900 mg Cd/person (i.e. 5.8 to 148 mg/kg bw for a 60 kg person). (europa.eu)
- Cadmium (Cd) is a toxic element that can negatively affect both humans and animals. (frontiersin.org)
- In addition, bioaccumulation of Cd in animals and humans has been reported, along the food chain, resulting in detrimental health effects ( 2 ) and perpetuating a persistent cycle of pollution. (frontiersin.org)
- Mild bronchiolar- monkeys and humans have more complex, non-neoplastic health effects of inhaled par- alveolar hyperplasia, which was much less larger acini than rats. (cdc.gov)
- 2007, "Cadmium-induced Cancers in Animals and in Humans", International Journal of Occupational and Environmental Health, v. 13 (2), pp. 202-212. (ujoh.org)
- The importance of these latter modes of action needs to be kept in mind when evaluating compounds that appear to increase risk of cancer in humans but that are not classic genotoxins. (who.int)
Chromium1
- Please note that all issuances of PCL or PCL exemption for Chromium VI Compounds are also covered under this, and the companies affected will need to apply for CCO Registration. (gov.ph)
Mortality1
- They have also sought to dig into the actual cause of this positive effect, which was a halving of cardiovascular mortality after 4 years of supplementation. (vitalraadet.dk)
Enters the environment2
Nausea1
- Poisoning may result from the ingestion of an acid food or drink prepared in a cadmium-lined vessel (e.g., lemonade served from cadmium-plated cans).Nausea, vomiting, diarrhea, and prostration usually occur within 15 minutes after ingestion and subside within 24 hours. (calgarysundevilsbasketball.ca)
Stabilizers1
- To begin, stabilizers in plastics prevent environmental effects of heat or UV light and mechanical degradation during processing and use. (ontarioyoga.net)
Copper2
- Cadmium metal is alloyed with copper in the production of automobile radiators. (dcceew.gov.au)
- Two small copper-cadmium alloy plants were studied in the United Kingdom. (inchem.org)
Dose2
- Physical activity and breast cancer risk: impact of timing, type and dose of activity and population subgroup effects. (mycanceriq.ca)
- 2,3,7,8-TCDD was particularly potent, inducing DNA damage in virtually all cells at 1 M. In conclusion, most of the toxins evaluated using the comet assay showed potential to induce DNA damage in hematopoietic cells, and the genotoxic effects were dose-dependent. (cdc.gov)
Concentration2
- In this study, effects of operation parameters like initial Cd(II) concentration, HCl concentration in the feed solution of SLM and applied voltage are investigated on separation efficiency, flux and permeability of the both processes. (jecst.org)
- Using the comet assay, 16 compounds at 10 nM concentration, induced a significant amount of DNA damage compared to the control. (cdc.gov)
Metal11
- Although initially indistinguishable from cadmium poisoning, metal fume fever is a separate and relatively benign disorder that generally resolves within 48 hours. (cdc.gov)
- Pure cadmium, the metal, is a soft silver white colour. (dcceew.gov.au)
- In the workplace, people are exposed where cadmium is used or generated, such as in battery manufacturing, metal soldering, or welding. (cdc.gov)
- European Union Risk Assessment Report: cadmium metal. (europa.eu)
- Effects of the carcinogenic metal cadmium on the regulation of mammalian gene expression are reviewed and discussed in the light of observations on interference with cellular signal transduction pathways. (nih.gov)
- Quaternary arsonium salts and their metal co-ordination compounds. (biodiversitylibrary.org)
- a. and its compounds, expressed as the metal c. (toronto.ca)
- 6 Cadmium is a heavy, non-biodegradable metal that is toxic to plants, people, and animals. (calgarysundevilsbasketball.ca)
- Cadmium is a soft silver-white metal that is usually found in combination with other elements. (calgarysundevilsbasketball.ca)
- See more ideas about heavy metal detox, cadmium poisoning, natural news. (calgarysundevilsbasketball.ca)
- While CdSe's properties make it a compelling choice for various applications, the use of cadmium, a toxic heavy metal, raises environmental and safety concerns that must be carefully managed. (refractiveindex.info)
Fragile bones1
- Other long-term effects are lung damage and fragile bones. (cdc.gov)
Cytotoxicity1
Hazardous2
- The REACH standard's main goal is to encourage the gradual replacement of the most hazardous compounds. (arenasolutions.com)
- Toxic air pollutants, also known as hazardous air pollutants, are those pollutants known or suspected to cause cancer or other serious health effects, such as reproductive effects, birth defects, or adverse environmental effects. (ny.gov)
Doses1
- Cadmium ingested in high doses irritates the gastric epithelium. (cdc.gov)
Environmental Protec1
- Cadmium has been found in at least 1,014 of the 1,669 National Priorities List sites identified by the Environmental Protection Agency (EPA). (cdc.gov)
Earth's1
- Cadmium is a natural element in the earth's crust. (cdc.gov)
Reproductive1
- These health effects can include damage to the immune system, as well as neurological, reproductive (e.g., reduced fertility), developmental, respiratory and other health problems. (ny.gov)
Chlorine1
- Second, antimony enhances the flame-retardant effect of chlorine in PVC. (ontarioyoga.net)
19981
- cadmium smelting and refining (Newman-Taylor 1998). (cdc.gov)