• Cold atmospheric plasma (CAP) has been reported to have strong anticancer effects in vitro and in vivo . (hindawi.com)
  • It is well-known that the hormone melatonin has oncostatic effects both in vivo and in vitro conditions in various types of cancers, including breast. (explorationpub.com)
  • The antiâ malarial drug artemisinin has shown anticancer activity in vitro and animal experiments, but experience in human cancer is scarce. (amhsr.org)
  • Green tea seems to exert a specific protective effect against colorectal and pancreatic cancer-two notoriously difficult cancers to treat. (doctorshealthpress.com)
  • Fangchinoline exerts anticancer effects on colorectal cancer by inducing autophagy via regulation AMPK/mTOR/ULK1 pathway. (stembook.org)
  • Collectively, our findings indicate the dual roles of aspirin on autophagy, and demonstrate a new mechanism by which Beclin 1 acetylation impairs the anticancer effect of aspirin in colorectal cancer cells. (oncotarget.com)
  • Using Ganoderma lucidum fruiting bodies (provided by Fujian Xianzhilou Biological Science and Technology Co., Ltd.) as the experimental material, the team first extracted the total triterpenes of Ganoderma lucidum from the fruiting bodies of Ganoderma lucidum with ethanol, and then further separated the neutral triterpenes and acidic triterpenes to explore their inhibitory effect on colorectal cancer. (ganoherb.com)
  • The researchers further evaluated the anti-tumor effects of Ganoderma lucidum neutral triterpenes in vivo through animal experiments: First, the human colorectal cancer cell line SW620 with lymphatic metastasis ability was implanted under the skin of nude mice (immune-deficient mice). (ganoherb.com)
  • According to the researcher's analysis, the above-mentioned neutral triterpenes of Ganoderma lucidum , which has an inhibitory effect on colorectal cancer, contain at least nine kinds of triterpenes (Figure 6). (ganoherb.com)
  • 1990. The effect of mild stress on DMH-induced colorectal cancer. (cdc.gov)
  • AIM: To explore the effect of human plasma alpha-1 antitrypsin (AAT) protein in the chemically induced mouse model of colorectal cancer. (lu.se)
  • Results of a new study by neuroscientists at the University of Massachusetts Amherst suggest that a new treatment approach is needed - and how this may be possible - to address adverse effects of aromatase inhibitors, drugs commonly prescribed to both men and women to prevent recurrence of estrogen-positive breast cancer. (umass.edu)
  • The authors state, "These findings suggest adverse effects of aromatase inhibitors on the primate brain and call for new therapies that effectively prevent breast cancer recurrence while minimizing side effects that further compromise quality of life. (umass.edu)
  • A randomized, controlled, double-blind, three-month study (n=53) reported significant improvement in urinary flow, urination time, residual urine, and urinary frequency without any adverse effects. (nutrimedical.com)
  • A review of the literature suggests that beta-sitosterol may cause GI adverse effects as well as impotence. (drugs.com)
  • In addition, some of the agents used for the treatment of breast cancer have adverse effects on bone (chemotherapy and aromatase inhibitors). (medscape.com)
  • Find out how oncology nurses can contribute to the safety of newly approved anticancer medications by reporting adverse effects. (medscape.com)
  • The goals of pharmacotherapy for deep venous thrombosis (DVT) are to reduce morbidity, to prevent the postthrombotic syndrome (PTS), and to prevent pulmonary embolism (PE), all with minimal adverse effects and cost. (medscape.com)
  • The study also adds to evidence that time-restricted feeding may promote longevity and have cancer-fighting effects. (medicalnewstoday.com)
  • Cannabinoids such as the main active component of marijuana have anticancer effects on human brain cancer cells, according to new research. (sciencedaily.com)
  • Guillermo Velasco and colleagues, at Complutense University, Spain, have provided evidence that suggests that cannabinoids such as the main active component of marijuana (THC) have anticancer effects on human brain cancer cells. (sciencedaily.com)
  • Teaming broccoli with broccoli sprouts may make the vegetables anti-cancer effect almost twice as powerful. (disabled-world.com)
  • A new University of Illinois study provides convincing evidence that the way you prepare and consume your broccoli matters, and also suggests that teaming broccoli with broccoli sprouts may make the vegetable's anti-cancer effect almost twice as powerful. (disabled-world.com)
  • Broccoli, prepared correctly, is an extremely potent cancer-fighting agent three to five servings a week are enough to have an effect. (disabled-world.com)
  • These data show that di-GA exhibits three distinct anticancer activities: induction of apoptosis, cell-cycle arrest and disruption of cancer cell-induced lymphendothelial disintegration. (nature.com)
  • She adds, "This drug is given to prevent recurrent breast cancer in humans and it does save lives, but a lot of times, patients are not compliant because of unpleasant side effects that affect quality of life. (umass.edu)
  • The patients have had cancer, so it's hard to disentangle the stress of their disease and treatment from the drug effects. (umass.edu)
  • Anticancer effects of the HDAC inhibitor, 3β,6β‑dihydroxyurs‑12‑en‑27‑oic acid, in MCF‑7 breast cancer cells via the inhibition of Akt/mTOR pathways. (iasp-pain.org)
  • The purpose of the present study was to investigate the histone deacetylase (HDAC) inhibitory and anticancer activities of ACT‑3 compared with suberoylanilide hydroxamic acid (SAHA) in MCF‑7 human breast cancer cells. (iasp-pain.org)
  • A team of scientists from the Institute of Molecular Genetics of the Czech Academy of Sciences has discovered which places in the DNA molecule inside cancer cells are the basis of the effect of anticancer drugs. (cas.cz)
  • Such compounds are attractive to researchers developing novel anti-cancer drugs, as conventional treatments - such as chemotherapy - are burdened by the therapy's cytotoxic effects on healthy cells. (technologynetworks.com)
  • In previous research, Kaempferia galanga L. extract - or KGE - demonstrated anti-cancer effects against Ehrlich ascites tumor cells (EATCs) in mice. (technologynetworks.com)
  • How this anti-cancer effect occurred, however, was not well understood. (technologynetworks.com)
  • 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay was executed for determination of effects of piperine on breast cancer cell viability. (ijpsonline.com)
  • Clonogenic assay was implemented for checking the effect of piperine on clonogenic potency of breast cancer cells. (ijpsonline.com)
  • In conclusion, the current investigation regarding anticancer effects of piperine against breast cancer revealed remarkable suppression of cancer cells. (ijpsonline.com)
  • In this study, we investigated the effect of aspirin on Beclin 1 acetylation and autophagy in CRC cells, providing new insight into aspirin for cancer therapy. (oncotarget.com)
  • The cytotoxic effects of the sonochemically synthesized G, AuNPs and G-Au nanocomposite were conducted on mammalian cell lines revealed the selective cytotoxic effects towards cancer cells and biocompatible nature towards normal cells. (nottingham.ac.uk)
  • The antibacterial effects, sensing potential and selective toxicity towards cancer and normal cells make this RGO-Ag nanocomposite a promising candidate for future health care industry. (nottingham.ac.uk)
  • Additionally, maintenance of the light-dark cycle and oral supplementation of melatonin may have a beneficial effect on women who are facing the risk of breast cancer [ 12 ]. (explorationpub.com)
  • This review will touch the oncostatic effects of melatonin in breast cancer and its possibilities in cancer treatment. (explorationpub.com)
  • The major cause of death from cancer is driven by the spread of tumor cells, which requires migration of cells," said study coauthor Timothy Fan , a professor of veterinary clinical medicine and veterinary oncology and member of the IGB's Anticancer Discovery From Pets to People research theme. (illinois.edu)
  • They also plan to study the effects of EDP-EAs derived from omega-3 fatty acids in other cancer types. (illinois.edu)
  • A PubMed search of about 127 papers on antiâ cancer effects of antimalarials has revealed that this class of drug, including other antimalarials, have several biological characteristics that include anticancer properties. (amhsr.org)
  • When overexpressed ectopically, anticancer genes preferentially kill cancer cells while sparing the normal healthy cells. (wikipedia.org)
  • In the late 1990s, research on cancer cells led to the identification of anticancer genes. (wikipedia.org)
  • Molecular Hydrogen Has Promising Anti-Cancer Effects! (h2hubb.com)
  • Let's examine the research and bring to light the possible therapeutic effects and advantages molecular hydrogen or hydrogen water has demonstrated in scientific studies to have against cancer. (h2hubb.com)
  • Anticancer Effect of Green Synthesized Gold Nanoparticles Using Orchid Extract and their Characterizations on Breast Cancer AMJ-13 Cell Line. (sysrevpharm.org)
  • On the whole, Ganoderma lucidum neutral triterpenes had significantly better inhibitory effects on cancer cell growth (proliferation) than Ganoderma lucidum acidic triterpenes (Figure 1). (ganoherb.com)
  • This means that ganodermanondiol can distinguish cancer cells from normal cells and give different "treatments", which is completely different from the "all killing" effect of chemotherapeutic drugs on good and bad cells. (ganoherb.com)
  • Consequently, ROS-modulation has emerged as an anticancer strategy with synthesis of various ROS-inducing or responsive agents that target cancer cells. (degruyter.com)
  • With an effective cancer therapy still lacking, these three compounds are good candidates for new anticancer research. (unab.cl)
  • The anticancer activity of these compounds was evaluated in colon cancer, HCT-116, and noncancerous, HEK-293, cell lines using the MTT antiproliferative assays. (mendeley.com)
  • Anti-cancer effect of doxorubicin is mediated by downregulation of HMG-Co A reductase via inhibition of EGFR/Src pathway. (bvsalud.org)
  • When it comes to helping cancer patients manage chemotherapy-related side effects, consistent informational support is key. (medscape.com)
  • The objective of this study was to investigate the association between persistent use of statins and the risk of overall and site-specific cancer in adults, to assess dose-response relationship, and to examine the effects of varying types of statins. (cdc.gov)
  • Furthermore, PAM had a significant cytotoxic effect on A549 cells but had little effect on normal cell viability. (hindawi.com)
  • The cytotoxic effect of anticancer drugs may promote a direct action that results in flaking, ulceration, xerostomia, and neurotoxicity, and an indirect action that causes the appearance of bleeding and opportunistic infections due to immunosuppression caused by the drug. (bvsalud.org)
  • After 13 days of experiments, it was found that the intervention of Ganoderma lucidum neutral triterpenes can make tumors grow slower and smaller, and its inhibitory effect is comparable to that of the chemotherapy drug 5-Fu (20 mg/kg intraperitoneal injection per day), but it doesn't cause serious weight loss like 5-Fu (Figure 2-5). (ganoherb.com)
  • As curcumin is safe and lacks systemic toxic effects in humans, it may be considered as a potential candidate to enhance the therapeutic effects of radiation and potentiate the efficacy of chemotherapy in the context of combination regimens. (current-pharmaceutical-design.com)
  • Their study found that aromatase inhibitors do indeed suppress estrogen synthesis in body tissues, but their unexpected findings in the brain could explain some of the negative effects and provide insight into more effective, less disruptive future therapies. (umass.edu)
  • According to our results, the mechanism for an adverse effect on memory may be due to an increase of estrogen synthesis in the hippocampus. (umass.edu)
  • Perhaps, future treatments could find a way to block this increased synthesis, and maybe prevent some of the negative side effects. (umass.edu)
  • In this review, we summarize the state-of-art research related to oxoisoaporphine, sampangine, and boldine, with emphasis on their structural characteristics and the relationship between structure, activity, methods of extraction or synthesis, and anticancer mechanism. (unab.cl)
  • Inhibition of HMG-CoA reductase by statin in effect prevents the synthesis of mevalonic acid, a precursor of nonsteroidal isoprenoids, lipid attachment molecules for small G proteins, such as Ras, Rho, and Rac. (cdc.gov)
  • Anticancer Effect in Human Glioblastoma and Antioxidant Activity ofL. (greenmedinfo.com)
  • The aim of the present study was to evaluate the phytochemical composition, antioxidant and anticancer activity ofaqueous and methanol extracts against Human glioblastoma cells U87MG. (greenmedinfo.com)
  • Digalloyl-resveratrol (di-GA) is a synthetic compound aimed to combine the biological effects of the plant polyhydroxy phenols gallic acid and resveratrol, which are both radical scavengers and cyclooxygenase inhibitors exhibiting anticancer activity. (nature.com)
  • The anticancer activity of 3β,6β‑dihydroxyurs‑12‑en‑27‑oic acid (ACT‑3), a major component isolated from , has not yet been investigated in detail. (iasp-pain.org)
  • The effects of ACT‑3 on HDAC enzyme activity were measured using assay kits. (iasp-pain.org)
  • While aspirin's ability to acetylate and inhibit COXs enzyme activity is well known [ 14 ], multiple cellular proteins can be acetylated by aspirin, suggesting that aspirin may exert its anticancer effect by acetylating multiple cellular targets [ 15 , 16 ]. (oncotarget.com)
  • Both ikarugamycin and astemizole improved the anticancer activity of the immunogenic chemotherapeutic agent oxaliplatin in a T cell-dependent fashion. (bmj.com)
  • exerted the survival or growth inhibitory effect on HL-60 human leukemia cells as well as antimutagenic activity, and the dichloromethane fr. (jcpjournal.org)
  • Since its discovery, many have searched for effective treatment, assessing different molecules for their anticancer activity. (unab.cl)
  • The effects of preharvest methyl jasmonate (MJ) application on fruit quality, antioxidant activity and flavonoid content in blackberries (Rubus sp. (cdc.gov)
  • Anticancer activity against human lung A549 cells and HL-60 leukemia cells was also evaluated. (cdc.gov)
  • SOR), hydrogen peroxide, and 2, 2-Diphenyl-2-picrylhydrazyl (DPPH) radical activity by a model (most biological y active) of the anticancer plant was also evaluated. (who.int)
  • The anticancer model's overal antioxidant activity (34.72 µg/mL) was slightly lower than quercetin (30.44 µg/mL) but higher than ascorbic acid (41.68 µg/mL). (who.int)
  • and anticancer properties (on samples of the human prostate cell line PC3), and its drug toxicity (on a sample of the human kidney cell line HEK293). (nih.gov)
  • Final Considerations: Clinical studies based on scientific evidence are required for the adaptation of protocols directed to the prevention and control of oral lesions arising from the toxicity of anticancer drugs. (bvsalud.org)
  • They also exhibit synergism with other anticancer drugs with no increased toxicity toward normal cells. (amhsr.org)
  • However, its use is limited by its dose -dependent side effects, such as cardiac toxicity . (bvsalud.org)
  • The current drug therapy is linked to such complaints as hot flashes, memory lapses, anxiety and depression, side effects so bothersome that some patients discontinue the life-saving treatment, the researchers point out. (umass.edu)
  • Anticancer therapy using cold atmospheric plasma (CAP) is a rapidly developing field through collaboration with physics, biology, chemistry, and medicine [ 1 - 6 ]. (hindawi.com)
  • One of the most studied sources for anticancer therapy is natural compounds and their derivates, like alkaloids, which are organic molecules containing nitrogen atoms in their structure. (unab.cl)
  • Anticancer therapy that consisted of radiation to the stomach and daily capecitabine and weekly paclitaxel was begun 5 days after discharge. (cdc.gov)
  • After 6 weeks of anticancer therapy (7 weeks after tularemia), the patient's carcinoembryonic antigen decreased substantially. (cdc.gov)
  • Effects of this therapy were evaluated histologically, and by immunohistochemical and gene expression assays. (lu.se)
  • Medicinal plants used by traditional medical practitioners (TMP) to treat cancers are considered safe when used alone or combined with conventional therapy to ensure their effectiveness and eliminate the toxic effects of orthodox medicines. (who.int)
  • Moreover, the MST1/2 inhibitor XMU-MP-1 not only partially rescued the inhibitory effect chaetocin-induced proliferation, but also rescued the chaetocin-induced apoptosis in ESCC cells. (aging-us.com)
  • Furthermore, in vivo results confirmed the antitumor effect of chaetocin and its relationship with Hippo pathway. (aging-us.com)
  • Li L , Jiang H , Li Y , Xiang X , Chu Y , Tang J , Liu K , Huo D , Zhang X , . Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway. (aging-us.com)
  • An international team of scientists led by Hana Hanzlíková from the Institute of Molecular Genetics of the Czech Academy of Sciences and Keith Caldecott from the University of Sussex in the United Kingdom discovered which sites in the DNA molecule inside tumour cells represent the basis of the effect of anticancer drugs (so-called PARP inhibitors). (cas.cz)
  • Therefore, the current investigation was designed to unveil the anticancer effects of piperine molecule against human breast carcinoma. (ijpsonline.com)
  • Boldine has also been tested as an anticancer molecule. (unab.cl)
  • showed the strongest inhibitory effect (more than 90%) among them. (jcpjournal.org)
  • Aug. 28, 2023 Scientists have verified the anticancer effects of Kencur, a tropical plant of the ginger family, mainly grown in Southeast Asia, in cell and animal experiments. (sciencedaily.com)
  • Although there are many scientific evidences for the anti-tumor effects of Ganoderma lucidum total triterpenes and acidic triterpenes, there are few studies on the role of Ganoderma lucidum neutral triterpenes in this regard. (ganoherb.com)
  • The excellent stability at physiological pH promotes its utilization of RGO dispersion as a carrier of Paclitaxel (Ptx) - an anticancer drug. (nottingham.ac.uk)
  • However, the use of paclitaxel is limited by undesirable side effects as well as the development of drug resistance. (lu.se)
  • These data indicated that ACT‑3 can be used as a promising anticancer agent to overcome the limitations and reduce the side effects of conventional anticancer drugs. (iasp-pain.org)
  • Conclusions These findings underscore the potential utility of this screening system for the identification of immunostimulatory drugs with anticancer effects. (bmj.com)
  • According to the pharmacokinetics of anticancer drugs and aspects such as frequency and duration of treatment, several oral side effects may be observed. (bvsalud.org)
  • Objective: To report the potential oral repercussions derived from the use of anticancer drugs. (bvsalud.org)
  • But we have a lot of work to do to understand the precise mechanism underlying these effects. (umass.edu)
  • Although evidence of aspirin's anticancer effect is compelling, the underlying molecular mechanism remains enigmatic. (oncotarget.com)
  • The exact mechanism of activation and molecular basis of these anticancer effects are not fully elucidated. (amhsr.org)
  • These compounds and their derivatives have unique structural properties that potentially have an anticancer mechanism. (unab.cl)
  • Among them, oxoisoaporphine and sampangine compounds are receiving increased attention due to their potential anticancer effects. (unab.cl)
  • The methylated flavonoids, compounds 1-3 and 5, were evaluated for their anticancer activities in comparison to the non-methylated parent flavonoids taxifolin (4) and quercetin (6). (mendeley.com)
  • Animal tumor models and apoptin-transgenic mice have shown apoptin to be a safe and effective anticancer agent which causes a significant tumor regression. (wikipedia.org)
  • H2 has been shown to reduce tumor invasion and tumor growth and because of this effect, H2 has been shown to have anti-tumor effects. (h2hubb.com)
  • Below is a non-comprehensive list of common anticancer genes. (wikipedia.org)
  • Chaetocin, a small molecular compound isolated from the marine fungus, exhibits potent anticancer effects. (aging-us.com)
  • Based on scientific research, molecular hydrogen appears to have promising anticancer effects. (h2hubb.com)
  • Molecular hydrogen in numerous studies has demonstrated an anti-apoptotic effect in health or injured cells. (h2hubb.com)
  • Studies have explored the anticancer properties of different fruits, both in terms of their extracts and bioactive ingredients. (nature.com)
  • L. egeregia was regarded as the prototype of the anticancer species due to its profound flavonoid concentration (85.40 µg/mL) and cytotoxicity (9.46 µg/mL) compared to other extracts. (who.int)
  • The antiviral, antibacterial, and anticancer properties of its chemo-skeleton have motivated this study to explore its efficacy in pharmaceutics. (nih.gov)
  • The molecules, called endocannabinoids, are made naturally by the body and have similar properties to cannabinoids found in marijuana - but without the psychotropic effects. (illinois.edu)
  • Presently, research is in progress for search of novel phytochemicals having anti cancerous properties with minimum or zero side effects. (researchsquare.com)
  • Taken together, our study demonstrates that chaetocin exhibits anticancer effects in ESCC via activation of Hippo pathway. (aging-us.com)
  • However, the anticancer effects of chaetocin on ESCC and its potential relationship to Hippo pathway remain unclear. (aging-us.com)
  • A potential cardioprotective effect was also suggested. (drugs.com)
  • However, little is known about the anticancer potential of Sapota fruits. (nature.com)
  • Samples of commonly utilized anticancer plants obtained from the chosen areas using physical and virtual oral seminars were studied for physiochemical composition and a possible antioxidant and cytotoxic potential to validate the basis for the use of the selected anticancer plants. (who.int)
  • Although it causes less cell death than direct treatment, it has minimal effects on normal cells, is easy to process and store plasma-generated RONS, and can be treated on large areas. (hindawi.com)
  • In the present study, the effects of ACT‑3 on anticancer effects of MCF‑7 cells were determined by measuring the level of apoptotic cell death and cell cycle regulator using flow cytometry analysis and western blot analysis, respectively. (iasp-pain.org)
  • The NSCLC-eradicating effect of astemizole plus oxaliplatin was lost on depletion of either CD4 + or CD8 + T cells, as well as on neutralization of IFN-γ. (bmj.com)
  • This concentration has no lethality on normal cells (mouse embryonic fibroblast cell line NIH3T3), and the concentration must be increased to more than 80 μg/mL to have a significant effect (inhibit the survival of half of mouse embryonic cell lines). (ganoherb.com)
  • Recent studies have shown that curcumin has therapeutic and radiosensitizing effects on NPC cells. (current-pharmaceutical-design.com)
  • Three hours after feeding, a definite synergistic effect was noted between the powder and the sprouts. (disabled-world.com)
  • Such data chal enge the "ca- and in experimental animals, with The four anticancer agents dis- nonical" site-specificity of carcino- reference to the possible underlying cussed here were first used in clin- ical practice in the 1960s, but since genesis. (who.int)
  • Thank you for your interest in spreading the word on Anticancer Research. (iiarjournals.org)
  • Message Body (Your Name) thought you would like to see the Anticancer Research web site. (iiarjournals.org)
  • Phytochemicals are viewed as appropriate possibility for anticancer medication advancements due to their pleiotropic activities on track occasions with numerous habits. (researchsquare.com)
  • After statins were introduced into clinical practice, they were shown to have effects other than lipid lowering, referred to as pleiotropic effects (7). (cdc.gov)
  • Dietary consumption of omega-3 fatty acids can lead to the formation of these substances in the body and may have some beneficial effects. (illinois.edu)
  • This study was conducted to evaluate the effects of protein isolation on dietary fibre and whey proteins of lupin flour. (edu.au)
  • A 1-year study in healthy patients consuming 1.6 g/day of plant sterols contained in a dietary spread demonstrated cholesterol-lowering effects as well as general tolerability with long-term consumption. (drugs.com)
  • Literature review: Among the oral effects observed in the body because of treatment, the most common changes occur in the oral mucosa, affecting the patient's quality of life, the length of hospital stay, and hospital costs. (bvsalud.org)
  • Online academic literature searches were done on the cited plants to identify the already-exploited anticancer plants. (who.int)
  • The scientists believe that it's the carotenoids in the tomatoes that are responsible for this protective effect against damage from UV light in the male mice. (naturalnews.com)
  • In the setting of metastatic disease, bisphosphonates have little or no effect on survival. (medscape.com)
  • Effects of 72 h treatment with Vitamin D-binding Protein-derived Macrophage-activating Factor (DBP-MAF) on MCF-7 cell proliferation. (iiarjournals.org)
  • Effects of 72 h treatment with Vitamin D-binding Protein-derived Macrophage-activating Factor (DBP-MAF) on MCF-7 cell morphology under phase-contrast light microscopy. (iiarjournals.org)
  • Numerous phytochemicals and their determined analogs have been recognized as possible contender for anticancer treatment and the present review article sheds light on few of these phytocompounds. (researchsquare.com)
  • In premenopausal women, however, bisphosphonate treatment had no apparent effect on any outcome. (medscape.com)
  • These data indicate that EGFR/Src/HMG-CR is a new pathway mediating doxorubicin -induced cell death and that cholesterol control could be combined with doxorubicin treatment to enhance efficacy and thus reduce side effects. (bvsalud.org)
  • In addition, another recent study in mice found that the eating pattern may even have anticancer effects. (medicalnewstoday.com)
  • 3H-dialkylhydrazines in the neuroendocrine system and their antigonadotropic effect in rats. (cdc.gov)
  • Beta-blockers marketed under the names Inderal, Lopressor, Corgard, Blocadren, and Tenormin have fewer side effects, but many people who take them still complain of sexual dysfunction. (healthyplace.com)
  • However, intravenously administered bisphosphonates do appear to provide a continuous effect on bone for the duration of their use. (medscape.com)