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  • distal
  • Current is passed through the metal end effector and through an insulated conduit to the distal tip of the ceramic end effector. (google.co.uk)
  • A connection at the distal tip of the ceramic end effector allows the. (google.co.uk)
  • 6. The bipolar instrument of claim 5 wherein said first and second end effectors each have an intermediate aperture and the clevis section has a distal end with two opposed wings and a pin interconnecting said opposed wings and passing through the intermediate apertures of the first and second end effectors. (google.co.uk)
  • 9. The bipolar instrument of claim 8 wherein said cam socket is received within a clevis section and said first and second end effectors each have an intermediate aperture and the clevis section has a distal end with two opposed wings and a pin interconnecting said opposed wings and passing through the intermediate apertures of the first and second end effectors. (google.co.uk)
  • In some embodiments these tools include a proximally-located actuator for the operation of a distal end effector, as well as proximally-located. (google.ca)
  • wherein
  • 2. The bipolar instrument of claim 1 wherein said second end effector has a cutting edge on its interfacing side. (google.co.uk)
  • 3. The bipolar instrument of claim 2 wherein the exposed electrode is recessed from the cutting edge by a distance sufficient to create a fulgurating gap when the first electrically conductive end effector is adjacent to the cutting edge. (google.co.uk)
  • 5. The bipolar instrument of claim 1 wherein said first and second end effectors are pivotably mounted in a clevis section. (google.co.uk)
  • 10. The bipolar instrument of claim 9 wherein the clevis section has a first electrical connector in contact with the electrically conductive end effector and a second electrical connector in contact with the conductor of the non-conductive blank. (google.co.uk)
  • 3 . The tool of claim 1 wherein the force limiter comprises a stop element engagable with the end effector actuator to stop its motion. (google.ca)
  • 4 . The tool of claim 1 wherein the force limiter is adapted to deform in response to actuation force delivered by the end effector actuator. (google.ca)
  • 7 . The tool of claim 6 wherein the spring is formed from a superelastic shape memory material treated so as to bend when the upper limit of the actuation force is applied to the end effector by the end effector actuator. (google.ca)
  • 10 . The tool of claim 1 wherein the end effector is operably connected to the end effector actuator at least in part through the force limiter. (google.ca)
  • 11 . The tool of claim 10 wherein the force limiter is disposed between the end effector actuator and the linkage. (google.ca)
  • 12 . The tool of claim 10 wherein the end effector actuator is operably connected to the linkage such that movement of the end effector actuator moves the linkage and such that movement of the end effector actuator with respect to the linkage varies when the upper limit of the actuation force is reached. (google.ca)
  • an articulation lock system interfacing with said articulation control system and said closure member, said articulation lock system configured to move from an unlocked position wherein said articulation control system applies said articulation motions to said end effector and a locked position wherein said articulation lock system prevents said articulation control system from applying said articulation motions to said end effector upon application of said closure motion by said closure member. (google.co.uk)
  • 4. The surgical instrument of claim 3 wherein said articulation lock system comprises a first locking member movably interfacing with said closure member and said first elongated articulation member such that, upon application of said closure motion to said end effector by said closure member, said first locking member is moved into locking engagement with said first elongated articulation member. (google.co.uk)
  • 5. The surgical instrument of claim 4 wherein said end effector is articulatable to various articulated positions and wherein said first elongated articulation member comprises a plurality of first locking positions corresponding to said various articulated positions. (google.co.uk)
  • catalytic
  • Therefore, the type I PAKs are considered classical RHO GTPase effector kinases because they display increased catalytic activity upon RHO binding, but the type II PAKs represent a more complicated example of GTPase control of kinase signaling. (pnas.org)
  • Here we report a new class of sequence-specific nucleases created by fusing transcription activator-like effectors (TALEs) to the catalytic domain of the Fok I endonuclease. (genetics.org)
  • Inspection
  • A probe attachment, connected to the end of the arm opposite the tube, provides motion in at least one axis relative to the arm for an inspection probe attached to the end effector. (google.com.au)
  • Cut-off switches can be used to alert a control system to a separation of the end effector from the bridge and proximity of the bridge to a structure under inspection. (google.com.au)
  • thereby
  • decreasing the protrusion of the at least one extension of the magnetic coupling offset release clamp between the end effector and the component, thereby decreasing the separation between the end effector and the component to permit the end effector and component to magnetically couple. (google.com.au)
  • mechanism
  • A force limiter mechanism protects the end effector and manipulated objects from the harm of potentially excessive force applied by the operator. (google.ca)
  • least
  • In both models, redox modulation reduced the expression of these effector components by at least fivefold. (nih.gov)
  • An end effector also includes a telescoping arm at least partially disposed inside a tube. (google.com.au)
  • cell
  • Description: This training workshop is designed to educate participants on two key perspectives: building quality into their immune effector cell programs and performing peer-based inspections. (factwebsite.org)
  • Physicians wishing to train to become an inspector for the FACT Immune Effector Cell Accreditation Program must meet prerequisite education and experience requirements, submit a satisfactory inspector application, attend an in-person training workshop, view online videos, and complete a test on the requirements. (factwebsite.org)
  • Effector said it seeks to develop small-molecule drugs for targets that continue to drive a cell toward cancer, even after a key oncogene has been silenced. (xconomy.com)
  • Research
  • Steve Worland, the former CEO of Anadys Pharmaceuticals, founded Effector with UCSF scientists Kevan Shokat and Davide Ruggero, whose research has focused on translation control and cancer. (xconomy.com)
  • response
  • The last treatment where leaves are inoculated with both effectors does not give the standard response for a gene-for-gene interaction. (apsnet.org)
  • In a gene-for-gene interaction, you would expect the RB gene product to recognize the IPI-O1 effector, which would result in a hypersensitive response. (apsnet.org)
  • multiple
  • There are multiple RHO-dependent effector kinases, and of these, the p21-activated kinases (PAK), are an important family. (pnas.org)
  • lock
  • An articulation lock allows the fixing and releasing of both neutral and articulated configurations of the tool and of consequent placement of the end effector. (google.ca)
  • A rotation lock provides for enablement and disablement of rotatability of the end effector. (google.ca)
  • An articulation locking system is provided to lock the end effector in a desired articulated position. (google.co.uk)
  • motion
  • The locking system interfaces with the closure member and is activated upon application of a closure motion to the end effector. (google.co.uk)
  • directly
  • We show that the RVDs of TAL effectors correspond directly to the nucleotides in their target sites, one RVD to one nucleotide, with some degeneracy and no apparent context dependence. (sciencemag.org)