• However, under the severe levels of oxidative stress that cause necrosis, the damage causes ATP depletion, preventing controlled apoptotic death and causing the cell to simply fall apart. (wikipedia.org)
  • Basal levels of oxidative stress were assessed by measuring urinary markers of nucleic acid damage and lipid peroxidation. (nau.edu)
  • The lower levels of oxidative stress in the fit individuals were not mediated by known effects of exercise training such as adiposity, HDL concentrations, or small molecular weight antioxidants. (nau.edu)
  • However, the exposure of these cells to excessive levels of oxidative stress by too high levels of ROS or too low levels of antioxidative protection will render these cells dysfunctional thereby failing the fertilization process and causing couples to be infertile. (hindawi.com)
  • MSC co-culture with skin fibroblasts from mitochondrial disease patients rescued aberrant mitochondrial morphology from a fission state to a more fused appearance indicating an effect of MSC co-culture on host cell mitochondrial network formation. (frontiersin.org)
  • Mitochondrial function or the ability to generate energy through OXPHOS (oxidative phosphorylation) is vital for cell homeostasis and its dysfunction has been linked to the pathogenesis of nearly all chronic diseases ( Pieczenik and Neustadt, 2007 ). (frontiersin.org)
  • To analyze the effect of homeopathic Arnica on mitochondrial oxidative stress induced by Ca 2+ plus inorganic phosphate and/or Fe 2+ -citrate-mediated lipid peroxidation through changes in oxygen consumption rates. (thieme-connect.de)
  • In oxidative stress conditions, in the presence of Ca 2+ and inorganic phosphate, animals receiving Arnica 30cH had a significant decrease in mitochondrial O 2 consumption compared to control animals. (thieme-connect.de)
  • Capicor administration increased the endogenous antioxidant defense, weakening the lipid peroxidation and oxidative modification of mitochondrial proteins. (ukrbiochemjournal.org)
  • The effects of caloric restriction (CR) on in vivo muscle mitochondrial function in humans are controversial. (medscape.com)
  • [ 12 ] The activity of key mitochondrial enzymes of the tricarboxylic acid cycle, β-oxidation, and the electron transport system, conversely, were unchanged, [ 12 ] leaving many unanswered questions regarding the effects of CR on muscle-specific mitochondrial function in humans. (medscape.com)
  • To date, there have been no randomized controlled trials that have examined the effects of long-term CR on muscle mitochondrial function in humans. (medscape.com)
  • We conducted an ancillary study to the CALERIE 2 randomized controlled trial to examine the effects of 12 months of 25% CR on in vivo skeletal muscle mitochondrial energetics, mitochondrial content, and markers of oxidative stress. (medscape.com)
  • The effect of the extract was studied on lipid peroxidation and antioxidant parameters in liver and gastrocnemius muscle of rats on attaining the rectal temperature (T(rec)) of 23 degrees C during C-H-R exposure and after recovery (T(rec)37 degrees C) from C-H-R-induced hypothermia. (nih.gov)
  • Results suggested that supplementation with seabuckthorn extract helps to reduce oxidative stress in liver and muscle of rats during C-H-R exposure and post-stress recovery. (nih.gov)
  • The purpose of the current study is to investigate the effect of aquatic Rosa damascena extract against the oxidative damage induced by aluminum chloride intoxication in Alzheimer's model of Wister rats. (scienceopen.com)
  • There are about 24,000 oxidative DNA adducts per cell in young rats and 66,000 adducts per cell in old rats. (wikipedia.org)
  • The present study emphasizes the anticarcinogenic effect of Tridham (TD), a polyherbal traditional medicine, on AFB 1 -induced HCC in male Wistar rats. (hindawi.com)
  • This study highlights the potent antioxidant properties of TD which contribute to its therapeutic effect in AFB 1 -induced HCC in rats. (hindawi.com)
  • The cytoprotective action of the green tea- catechins against ethanol - or restraint plus water -immersion stress-induced acute gastric mucosal injury, and acetic acid-induced chronic gastric ulcers in rats has been reported. (rsc.org)
  • The antioxidant effects of Portulaca oleracea seeds extract (POS) and its fertility-enhancing effects were inspiring to evaluate the protective potential and pinpoint the mechanisms and molecular targets of the UPLC-MS fingerprinted POS extract on ACR-induced testicular toxicity in rats. (biomedcentral.com)
  • Also, purslane exerted anti-fertility effect in female rats by disrupting ovulation and female fertility hormones [ 18 ], while it diminished aging alterations in female reproductive system in aged mice [ 19 ]. (biomedcentral.com)
  • In this study, our aim was to study the effects of PTX on free oxygen radicals and oxidative damage in rats with ACS model. (hakanyanar.com)
  • UNLABELLED The aim of this study was to investigate the effect of lipoic acid (LA) on lipid peroxidation , hydrogen peroxide concentration (H2O2), sulphydryl group (-SH) contents and total capacity protein a few hours after administration lipopolysaccharide (LPS) -induced oxidative stress in rats . (bvsalud.org)
  • We investigated the in vitro antioxidant potential of hydroethanolic extract (HEE) from Bowdichia virgilioides on muscular damage and oxidative stress in rats subjected to high-intensity RT. (biomedcentral.com)
  • In this study, we investigated in adult Long-Evans rats the effect of the alteration of CN production through the ACN metabolism on the promotion of NIHL by ACN. (cdc.gov)
  • This study investigated the effect of the trans-resveratrol supplementation on the cardiac oxidative stress in rats exposed to cigarette smoke. (bvsalud.org)
  • Our findings evidenced the cardioprotective effect of trans- resveratrol in rats exposed to cigarette smoke. (bvsalud.org)
  • Moreover, oxidative stress also activates mechanisms that result in a glia-mediated inflammation that also causes secondary neuronal damage. (unboundmedicine.com)
  • A clearer appreciation of the potential therapeutic utility of antioxidants would emerge only when the complexity of their effects on mechanisms that interact to determine the extent of oxidative damage in vivo are more fully defined and understood. (unboundmedicine.com)
  • Excitotoxicity, a critical process in neurodegeneration, induces oxidative stress and neuronal death through mechanisms largely unknown. (nature.com)
  • Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling. (wikipedia.org)
  • Both hepatitis B virus (HBV) and hepatitis C virus (HCV) appear to be particularly more potent in inducing oxidative stress, suggesting unique mechanisms that are activated by these viral infections. (hindawi.com)
  • Of course, cells have a number of mechanisms in place to remove oxidative species, restoring the chemical balance of the cell. (virallfeed.xyz)
  • Biochemical and genetic mechanisms of oxidative stress (OS) developing in rat heart mitochondria were studied in a rotenone model of Parkinson's disease (PD), and the effect of Capicor (combination of meldonium dihydrate and gamma-butyrobetain dihydrate) on these mechanisms was evaluated. (ukrbiochemjournal.org)
  • In this review, we studied on the effects and molecular mechanisms of Rhizoma coptidis on NF-κB/MAPK/PI3K-Akt/AMPK/ERS and oxidative stress pathways. (springer.com)
  • As a traditional Chinese medicine, Rhizoma coptidis has excellent therapeutic effects on various diseases, but the underlying systematic molecular mechanisms are still far from being fully elucidated. (springer.com)
  • Mechanisms of oxidative stress in the potentiation of noise -induced hearing loss by acrylonitrile. (cdc.gov)
  • establish mechanisms of action by studying the effects of the same chemicals in experimental animals and on human cells in vitro, allowing for a better prediction of human carcinogenicity and assessment of carcinogenic mechanisms. (who.int)
  • The review comprehensively explores the literature for evidence of the role of oxidative stress in conditions such as abortions, preeclampsia, hydatidiform mole, fetal embryopathies, preterm labour and preeclampsia and gestational diabetes. (nih.gov)
  • Using isoprostanes as biomarkers of oxidative stress: some rarely considered issues. (degruyter.com)
  • It is concluded that weight loss improves the n-3 LCPUFA status of obese patients in association with significant amelioration in the biomarkers of oxidative stress, membrane FA insaturation, and n-3 LCPUFA biosynthesis capacity, thus representing a central therapeutic issue in the improvement of obesity-related metabolic alterations involved in the mechanism of hepatic steatosis. (arasysperfector.com)
  • The patho-physiological characteristic of AD is abnormal deposition of fibrillar amyloid β protein, intracellular neurofibrillary tangles, oxidative damage and neuronal death in the brain. (springer.com)
  • Since oxidative stress activates protein kinase D1 (PKD1) in tumor cells, we investigated the effect of excitotoxicity on neuronal PKD1 activity. (nature.com)
  • The early administration of LA a significant decreased symptoms of oxidative stress - induced LPS, that shows decrease in lipid peroxidation process, H2O2 concentration and increase in -SH groups and protein contents in rat 's lung homogenates. (bvsalud.org)
  • The focus of these studies was to measure the oxidation and nitration status of this important proapoptotic protein, consistent with the hypothesis that oxidative modification of p53 could be involved in the neuronal loss observed in neurodegenerative conditions. (uky.edu)
  • To followup these promising preliminary findings, we tested the efficacy of two doses of supplemental calcium (1.0 or 2.0 g/day) relative to placebo on modulating circulating biomarkers of inflammation [C-reactive protein (CRP) and 10 cytokines] and oxidative stress (F2-isoprostanes) over a 4-month treatment period among 193 patients with previous sporadic, colorectal adenoma in a randomized, double-blinded, placebo-controlled clinical trial. (umn.edu)
  • As OS biomarkers, lipid peroxidation, protein oxidative modification, H 2 O 2 production, the activity of MnSOD, GPx and glutathione pool indexes were measured. (ukrbiochemjournal.org)
  • Rotenone intoxication increased the intensity of lipid peroxidation, protein oxidative modification, and H 2 O 2 production. (ukrbiochemjournal.org)
  • The effect of Capicor on the protein markers of oxidative stress development in rat brain mitochondria under modeling of Parkinson's disease. (ukrbiochemjournal.org)
  • Additionally, continual oxidative stress from CCl 3 causes DNA damage, protein malfunction, and disrupted calcium homeostasis. (cdc.gov)
  • Western blotting was performed to examine the protein expression levels of endoplasmic reticulum stress (ERS)‑associated factors. (spandidos-publications.com)
  • Oxidative stress is an imbalance between free radicals and antioxidants in your body. (h-h-c.com)
  • Mango (Mangifera indica L.) is one of the world's most consumed fruit, and it is also a rich source of antioxidants that may prevent oxidative stress. (udea.edu.co)
  • Then, the brain is often exposed to excessive oxidative stress from neurotransmitter metabolism, and the question for the researchers was whether levels of antioxidants in the nucleus accumbens could affect motivation. (virallfeed.xyz)
  • This study tested the hypothesis that physically fit older adults would have less oxidative stress than unfit age-matched controls, due to greater circulating concentrations of non-enzymatic antioxidants and greater capacity to upregulate antioxidant enzymes. (nau.edu)
  • Ovulation-induced oxidative base damage and damage to DNA of the ovarian epithelium can be prevented by antioxidants. (nih.gov)
  • Natural antioxidants can reduce oxidative damage caused by high-intensity resistance training (RT). (biomedcentral.com)
  • However, other studies suggest that chronic exercise may cause depletion of antioxidants, which may increase exercise-induced oxidative stress and tissue damage if combined with diminished ingestion of antioxidants [ 22 ]. (biomedcentral.com)
  • Oxidative stress associated with NAFLD in obese patients represents a nutritional type of phenomenon, resulting from prolonged excess oxidative load (carbohydrates, lipids) and inadequate nutrient supply (dietary antioxidants) favoring pro-oxidant reactions (Sies et al. (arasysperfector.com)
  • Significant exposure to Aflatoxin B 1 (AFB 1 ), a potent hepatotoxic and hepatocarcinogenic mycotoxin, plays a major role in liver carcinogenesis through oxidative tissue damage and p53 mutation. (hindawi.com)
  • Inflammation and oxidative stress play important roles in colorectal carcinogenesis. (umn.edu)
  • Our results illustrate that administration of R. damascene extract has a protective effect against the oxidative damage induced by AlCl 3 intoxication in Alzheimer's model. (scienceopen.com)
  • Many studies reported that oxidative and nitrosative stress might be important for the pathogenesis of Alzheimer's disease (AD) beginning with arguably the earliest stage of AD, i.e., as mild cognitive impairment (MCI). (uky.edu)
  • Increased free radical activity ( oxidative stress ) appears to fuel Alzheimer's pathology - acting simultaneously as a mediator, product, and trigger for this "clogging" process and its related neural damage. (diagnose-me.com)
  • and advancements in science in developed countries have made it possible for people affected by this syndrome to live longer, but an extended life span has brought with it Alzheimer's disease (AD), which exacerbates the cognitive decline in these individuals. (bvsalud.org)
  • 2002). The aetiology and pathogenesis of neurodegenerative disorders is not fully understood, but it is known that inflammation and oxidative damage are a key component. (unimib.it)
  • Neopterin, Inflammation, and Oxidative Stress: What Could We Be Missing? (mdpi.com)
  • Both Zn deficiency and Zn overload may affect cellular Zn distribution and be linked to neurodegeneration in AD. (springer.com)
  • ROS and RNS can also indirectly contribute to tissue damage by activating a number of cellular pathways resulting in the expression of stress-sensitive genes and proteins to cause oxidative injury. (unboundmedicine.com)
  • Oxidative stress is an important activator of PKD1 in cellular models, but its capacity to activate this kinase in vivo is largely unknown. (nature.com)
  • Of note, DAPK can activate PKD in HeLa cells under oxidative stress conditions 11 , thus suggesting that PKD activation may contribute to cellular death. (nature.com)
  • Further, some reactive oxidative species act as cellular messengers in redox signaling. (wikipedia.org)
  • Activation of this receptor leads to increased oxidative stress that may result in cellular damage. (diagnose-me.com)
  • Oxidative stress from oxidative metabolism causes base damage, as well as strand breaks in DNA. (wikipedia.org)
  • The idea behind the study was that the brain itself - like all tissues in our body - is subjected to constant oxidative stress, as a result of the metabolism process. (virallfeed.xyz)
  • Arsenic metabolism efficiency did not have a clear effect on the concentrations of either of these biomarkers. (lu.se)
  • For this purpose, two different drugs were used: (1) Sodium thiosulfate (STS), a CN antidote commonly used in humans in case of CN poisoning and (2) 4-methylpyrazole (4MP) which blocks ACN metabolism through the oxidative pathway, preventing CN formation. (cdc.gov)
  • Protective effects of Mangifera indica L extract (Vimang), and its major component mangiferin, on iron-induced oxidative damage to rat serum and liver. (udea.edu.co)
  • The supplementation with POS extract may provide a potential protective effect for ACR-induced testicular dysfunction which is mediated by its antioxidant, antiapoptotic and steroidogenic modulatory effects. (biomedcentral.com)
  • Their paper, titled Protective Effect of Lemon Peel Extract on Oxidative Stress in H9c2 Rat Heart Cell Injury , was published in the academic journal Drug Design, Development and Therapy. (limoneira.com)
  • The in vitro test exposed the lemon peel extract to a specific type of rat heart cell with oxidative damage. (limoneira.com)
  • Natural News) Chinese researchers investigated the effects of Moringa oleifera stem extract (MOSE) on cataract formation induced by oxidative stress in cultured mouse lenses. (naturalnews.com)
  • Melatonin inhibits cholesterol secretion from the gallbladder, helps convert cholesterol to bile, and as an antioxidant can reduce oxidative stress on the gallbladder. (diagnose-me.com)
  • Although previous studies have found that intermediate spring and summer rainfall and warmer temperatures favor cub survival, counterintuitively these conditions were associated with more severe oxidative damage. (ox.ac.uk)
  • Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. (wikipedia.org)
  • ‌Because free radicals deplete your cell tissue, oxidative stress may have enduring repercussions. (h-h-c.com)
  • This review focuses on the differential responses of cell types to ATZ toxicity, testicular effects of ATZ in both in vitro and in vivo models and chemopreventive strategies, so as to highlight the current state of the art on the toxicological outcomes of ATZ exposure in several experimental model systems. (frontiersin.org)
  • There is strong evidence that calcium reduces risk for colorectal neoplasms, possibly through its ability to bind bile acids and prevent their colonic toxicity (which occurs via an oxidative mechanism and results in an inflammatory response). (umn.edu)
  • Very little is known about the general toxicity of these compounds, especially about their possible neurotoxic effects at the cell level. (imi.hr)
  • The question as to what causes the destruction of the dopamine-producing cells has puzzled researchers for years but a consensus is now emerging that Parkinson's disease is caused by oxidative stress and metal toxicity. (diagnose-me.com)
  • Carbon Tetrachloride Toxicity: What Are the Toxicological Effects of Carbon Tetrachloride Exposure? (cdc.gov)
  • Suwimol S, Pimpanit L, Aporn M, Pichita S, Ratiyaporn S, Wiroj J. Impact of Fruit and Vegetables on Oxidative Status and Lipid Profiles in Healthy Individuals. (udea.edu.co)
  • 15 Castilho R.F., Meinicke A.R., Alemida A.M., Hermes-Lima M., Vercesi A.E. Oxidative damage of mitochondria induced by Fe(II)citrate is potentiated by Ca 2+ and includes lipid peroxidation and alterations in membrane proteins. (thieme-connect.de)
  • Oxidative stress pathways are caused by the imbalance of oxidation and antioxidation in body. (springer.com)
  • ABSTRACT Currently no reports are available from Egypt regarding occupational exposure to nickel and its effects on the liver. (who.int)
  • Inhibition of miR‑132 activated PGC‑1α/Nrf2 signalling and inhibited oxidative stress and the expression of the pyroptosis‑related proteins NLRP3, caspase‑1 and IL‑1β, which were all reversed by inhibiting SIRT1 with EX527. (spandidos-publications.com)
  • The findings of the present study indicated that inhibition of miR‑132 may ameliorate myocardial I/R injury by inhibiting oxidative stress and pyroptosis through activation of PGC‑1α/Nrf2 signalling by targeting SIRT1. (spandidos-publications.com)
  • LPE has the potential to be developed into natural medicine or health food for the inhibition of cell oxidative damage. (limoneira.com)
  • The mechanism by which ACN renders the cochlea more vulnerable to noise damage is still unknown, but we hypothesize that the decrease of GSH and/or the inhibition of SOD reduce the cochlear intrinsic anti-oxidant defenses and ultimately create oxidative stress. (cdc.gov)
  • The aim of the study was to evaluate the anti-cancer effect and mechanism of action of SiNPs in breast cancer cell lines. (mdpi.com)
  • The present study aimed to explore the functional effects and regulatory mechanism of FOXA2 in pneumonia. (spandidos-publications.com)
  • Inflammation in the body is also caused by several lifestyle factors such as excessive drinking, chronic stress, excessive smoking etc. (h-h-c.com)
  • Overall, our results provide no evidence that calcium supplementation favorably modulates concentrations of circulating biomarkers of inflammation or oxidative stress over 4 months among patients with a previous colorectal adenoma. (umn.edu)
  • The supplementation of Trans-resveratrol attenuated the cardiac oxidative stress and increased the activity of catalase. (bvsalud.org)
  • Co-exposure to carbon black and Fe2O3 particles causes a synergistic oxidative effect that is significantly greater than the additive effects of exposures to either particle type alone. (rti.org)
  • The aim of this study was to address these gaps by assessing the toxic effects of 24-hour exposure to LSD and PCP in the concentration range of 0.39-100 µmol/L in the human neuroblastoma SH-SY5Y cell line. (imi.hr)
  • Describe the toxicological effects associated with carbon tetrachloride (CCl 4 ) exposure. (cdc.gov)
  • The immediate effect of acute CCl 4 exposure by all routes is CNS depression [Laine and Riihimaki 1986]. (cdc.gov)
  • The intensity of the effects is proportional to exposure dose. (cdc.gov)
  • The CNS effects of chronic exposure are open to question. (cdc.gov)
  • Sensorimotor neuropathy and abnormalities of vision have been reported, but epidemiological data are insufficient to support an association between CCl 4 exposure and these effects [O'Donoghue 2000]. (cdc.gov)
  • Acute hepatic injury usually manifests after CNS effects have subsided, typically 1 to 4 days after acute exposure. (cdc.gov)
  • In contrast, expression of an active dephosphorylation-resistant PKD1 mutant potentiates the IKK/NF-κB/SOD2 oxidative stress detoxification pathway and confers neuroprotection from in vitro and in vivo excitotoxicity. (nature.com)
  • Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo. (ukrbiochemjournal.org)
  • Neurons are most susceptible to direct oxidative injury by ROS and RNS. (unboundmedicine.com)
  • We found age class effects: cubs were more susceptible to oxidative stress and oxidative damage than adults, especially very young cubs in the spring, when they also exhibited lower antioxidant biomarkers than adults. (ox.ac.uk)
  • To evaluate the neuroprotective and neurite outgrowth effects of maltol, a natural aroma compound, on retinal ganglion cells (RGCs) under oxidative stress in vitro. (molvis.org)
  • With this in mind, the present study investigates whether maltol attenuates oxidative stress injury in primary RGCs in vitro. (molvis.org)
  • The administration of LA after to LPS -induced oxidative stress caused a significant decrease in TBARS and H2O2 concentrations (appropriate 3.65 +/- 0.2 microM and 0.014 +/- 0.008 microM) compared with the group treated with LPS (appropriate 6.030 +/- 0.16 microM and 0.189 +/- 0.03 microM). (bvsalud.org)
  • After cell viability was established, cells treated with concentrations that reduced their viability up to 30 % were further subjected to the alkaline comet assay and biochemical assays that enable estimation of oxidative stress-related effects. (imi.hr)
  • This study was conducted to evaluate the effects of a diesel particulate filter (DPF) regeneration process on the concentrations and size distributions of aerosols in an underground mine. (cdc.gov)
  • However, oxidative stress has emerged as a key player in the development and the progression of liver cirrhosis [ 4 ] which is known to be a precursor of HCC. (hindawi.com)
  • Our aim was to study the influence of weight loss on the fatty acid (FA) composition of liver and erythrocyte phospholipids and oxidative stress status in obese, non-alcoholic, fatty liver disease (NAFLD) patients. (arasysperfector.com)
  • The primary effects of CCl 4 in humans are on the central nervous system (CNS), liver, and kidneys. (cdc.gov)
  • The levels of peroxisome proliferator‑activated receptor gamma coactivator (PGC)‑1α/nuclear factor erythroid‑2‑related factor 2 (Nrf2) signalling, oxidative stress and pyroptosis‑related proteins were detected by western blotting. (spandidos-publications.com)
  • The intracellular redox reaction between carbon black and Fe3+ is likely responsible for the synergistic oxidative effect. (rti.org)
  • Oxidative stress pathways regulate redox balance by Nrf2 and other ways. (springer.com)
  • Recent studies showed that pentoxifylline (PTX) has effects on increasing tissue oxygenation, healing capillary refill and reducing superoxides and hydroxyl radicals by inhibiting xanthine oxidase. (hakanyanar.com)
  • Evidence presented in this review implicated that Rhizoma coptidis exerted beneficial effects on various diseases by regulation of NF-κB/MAPK/PI3K-Akt/AMPK/ERS and oxidative stress pathways, which support the clinical application of Rhizoma coptidis and offer references for future researches. (springer.com)
  • In this review, we sorted out the relationship of Rhizoma coptidis among components, diseases and NF-κB/MAPK/PI3K/Akt/AMPK/ERS/oxidative stress pathways, systematically studying on how Rhizoma coptidis exerts beneficial effects to various diseases, which supported the clinical application of Rhizoma coptidis and provided references for the future researches. (springer.com)
  • Targeted transcriptional profiling showed no effects on pathways involved inmitochondrial biogenesis, function, or oxidative stress. (medscape.com)
  • The purpose of this review is to summarize the current evidence in support of this critical role played by oxidative stress of neuronal and glial origin in neurodegenerative diseases. (unboundmedicine.com)
  • Oxidative stress and its significant roles in neurodegenerative diseases and cancer. (udea.edu.co)
  • This oxidative stress significantly increased the number of TUNEL-positive RGCs, but the maltol drastically reduced the proportion of those apoptotic cells. (molvis.org)
  • However, after it was discovered that oxidative stress injury to retinal ganglion cells (RGCs) is a leading pathophysiology of glaucoma [ 2 ], researchers' attention has turned to how to directly rescue the damaged RGCs from fatal oxidative stress. (molvis.org)
  • The body, in turn, attempts to detoxify the cells that have been affected. (limoneira.com)
  • Our findings suggest that LSD has a greater DNA damaging potential and stronger oxidative activity than PCP in SH-SY5Y cells. (imi.hr)
  • Biological effects of single-base damage by radiation or oxidation, such as 8-oxoguanine and thymine glycol, have been extensively studied. (wikipedia.org)
  • DNA damage induced by ionizing radiation is similar to oxidative stress, and these lesions have been implicated in aging and cancer. (wikipedia.org)
  • In addition, we found that isolated islets from Chop -/- mice displayed increased expression of UPR and oxidative stress response genes and reduced levels of oxidative damage. (jci.org)
  • there is no definitive study which has shown that maltol effectively protects them from the devastating effects of oxidative stress. (molvis.org)
  • 2 Conforti A., Bellavite P., Bertani S., Chiaroti F., Menniti-Ippolito F., Raschetti R. Rat models of acute inflammation: a randomized controlled study on the effects of homeopathic remedies. (thieme-connect.de)
  • Effect of homeopathy on analgesic intake following knee ligament reconstruction: a phase III monocentre randomized placebo controlled study. (thieme-connect.de)
  • The effect of the homeopathic remedies Arnica montana and Bellis perennis on mild postpartum bleeding - a randomized, double-blind, placebo-controlled study - preliminary results. (thieme-connect.de)
  • With a recent Italian study hypothesizing a significant correlation between T4-only levothyroxine use and lung cancer because of " oxidative stress " (possibly due to the serum peak of T4), or the same oxidative stress simply from the hypothyroidism itself, it spurs curiosity as to what oxidative stress is about and what we, as thyroid patients, can learn from this biological phenomena! (stopthethyroidmadness.com)
  • Our 3-yr field study investigated the effects of seasonal weather conditions on biomarkers for oxidative stress, oxidative damage, and antioxidant defense in the European badger (Meles meles). (ox.ac.uk)
  • A 2021 study by Chinese researchers added to the weight of evidence that lemon peel, rich in many bioactive compounds, can inhibit oxidative stress at the level of the cell. (limoneira.com)
  • Therefore, this study was conducted to investigate the effects of LJP on exercise endurance and oxidative stress in a forced swimming mouse model. (biomedcentral.com)
  • The purpose of this study was to assess the effects of hyperbaric oxygen (HBO) and near-infrared light therapy on wound healing. (researchgate.net)
  • A study to compare the effects of particles generated by engine fueled with neat biodiesel and neat petroleum-based diesel. (cdc.gov)
  • Furthermore, pro-oxidant activity can induce either beneficial or harmful effects in biologic systems. (diagnose-me.com)
  • Effects of Weather Conditions on Oxidative Stress, Oxidative Damage, and Antioxidant Capacity in a Wild-Living Mammal, the European Badger (Meles meles). (ox.ac.uk)
  • Winter carryover effects were partially evident, with drier and milder conditions associated with greater oxidative damage in the following spring but also with higher antioxidant capacity. (ox.ac.uk)
  • Modeling biomarkers against projected climate change scenarios predicted greater future risks of oxidative damage, although not necessarily exceeding antioxidant capacity. (ox.ac.uk)
  • Maltol has potential as a new neuroprotective therapeutic agent for oxidative stress-related ocular diseases, including glaucoma. (molvis.org)