Effect on bone bone development. Medical search. Frequent questions

The treatment did not affect total IGF-I levels, IGFBPs, or serum markers of bone formation and resorption. (nih.gov)
Some implantologists 6 - 8 see evidence that implant placement may be protective against alveolar bone resorption by stimulating continuous bone remodeling, and thus may actually be protective against typical oral bone loss due to the aging process. (allenpress.com)
The objective of this research was to establish whether individuals with clinical low bone mineral density (osteoporosis or osteopenia) would successfully retain dental implants, and whether dental implants, like natural teeth, are protective against alveolar bone resorption through stress-bearing and occlusal load factors, which stimulate continuous bony remodeling. (allenpress.com)
Continuous treatment with calcitonin (CT) to inhibit osteoclastic bone resorption results in acquired resistance. (edu.au)
What determines the switch from bone formation to resorption has been unclear. (sciencedaily.com)
Nevertheless, the molecular and cellular mechanisms terminating osteoblastic bone formation and promoting osteoclastic bone resorption remain elusive," explains senior author Masaru Ishii. (sciencedaily.com)
In this study, we established an advanced high-resolution microscopy system to visualize extracellular vesicles secreted and captured by mature osteoblasts in vivo and identified a subset of osteoblast-derived vesicles limiting bone formation and stimulating osteoclast differentiation, thus regulating the switch from bone formation to bone resorption through a microRNA (miRNA)-mediated mechanism," says Ishii. (sciencedaily.com)
Oct. 26, 2023 Research finds an overlap in the mechanism of hair color determination and bone resorption, which is associated with bone related diseases like osteoporosis. (sciencedaily.com)
Furthermore, RES was shown to be able to suppress the expression of osteoclastogenic factors and inhibit osteoclast formation, suggesting its potential in preventing osteoclast formation and, thus, bone resorption following MTX chemotherapy. (nutraingredients.com)
The study also revealed stimulation of both bone formation and resorption activity. (naturalproductsinsider.com)

In this paper we report the results of the first mechanical tests to quantify the effect of hypothyroidism, during post-natal development, on the skeletal properties of a precocial bird, the barnacle goose, as determined by microhardness testing. (reading.ac.uk)
Osteoporosis is a common bone-resorptive, host-dependent, multifactorial, and systemic skeletal disease generally affecting older females, marked by reduced bone strength, decreased bone mineral density and microarchitectural deterioration of bone tissue, resulting in increased bone fragility and risk of bone fracture. (allenpress.com)
It is clinically necessary to understand the effects of skeletal low bone mineral density and treatment for osteoporosis with oral bisphosphonates on dental implant success. (allenpress.com)
However, this relationship may not be valid for individual alcohol consumers, as small quantities of alcohol can have detrimental skeletal effects and not all studies report clinically relevant bone loss with long-duration alcohol abuse. (springer.com)
We propose that the interplay between intrinsic factors (e.g., age, sex, skeletal site) and extrinsic factors (e.g., age of onset of drinking, duration of drinking, comorbidities) influence the precise impact of alcohol consumption on bone health. (springer.com)
Skeletal turnover, bone mineral density, and fractures in male chronic abusers of alcohol. (springer.com)
Current approaches of regenerative therapies constitute strategies for bone tissue reparation and engineering, especially in the context of genetical diseases with skeletal defects. (hindawi.com)
However, their effects on bones and skeletal muscles are controversial, as some studies have reported positive effects while others have reported adverse effects. (stopumts.nl)
In this study, the effects of radiofrequency radiation (RFR) on bone biomechanics and skeletal muscle tissues were investigated in diabetic and healthy rats. (stopumts.nl)
In addition to enhancing skeletal growth and muscle development, several compounds in eggs, such as lutein, zeaxanthin and choline, may also improve memory and cognitive function. (scienceblog.com)
So, I think the two aspects of the study, the skeletal growth development and the cognition, will really make a nice contribution to pediatric literature. (scienceblog.com)
In the simulation study, to evaluate the effect on BSI accuracy, bone scans of a virtual phantom with predefined skeletal tumor burden (phantom-BSI) were simulated against the range of image counts (0.2, 0.5, 1.0, and 1.5 million) and separately against the resolution settings of the γ-cameras. (snmjournals.org)

Twenty healthy females ages 50-80 with confirmed osteoporosis or osteopenia, and 10 age- and gender-matched subjects with normal bone density (controls) received dental implants. (allenpress.com)
Some theorized that it is important to replace missing teeth with implants to ensure function by duplicating loading and ensuring bone density. (allenpress.com)
Other studies report association between low bone mineral density and tooth loss in men 14 , 15 and postmenopausal women. (allenpress.com)
For edentulous individuals, residual ridge height correlates with both total body calcium and mandibular bone mineral density. (allenpress.com)
Alcohol consumption and bone mineral density in elderly women. (springer.com)
CT allows both the acquisition of bone morphology and measurement of bone density in a living individual. (hindawi.com)
Sclerosing bone disorder (SBD) is a heterogeneous group of monogenic diseases characterized by increased bone density. (nature.com)
High intake of vitamin D is recommended during nutritional treatment for anorexia nervosa, and it is crucial to monitor bone density both early on and in the long term. (gu.se)
Modified Atkins diet can be considered a safe treatment for childhood cases regarding growth and bone density. (gu.se)
We also studied how bone density and growth are affected in children and adolescents receiving MAD as a treatment for severe epilepsy. (gu.se)
However, anorexia nervosa patients had lower bone density compared to a control group of healthy young women. (gu.se)
The results also emphasize the importance of early bone health evaluation in young women with anorexia nervosa and the need for a structured long-term follow-up of bone density," says Anna Svedlund. (gu.se)
We also observed no negative impacts on their growth or bone density during 24 months of MAD treatment. (gu.se)
In a newly published study, Forteo significantly reduced the incidence of spinal and non-spinal fractures and increased bone mineral density in post-menopausal women with osteoporosis. (imaginis.com)
Additionally, women who received Forteo experienced increases in bone mineral density as early as three months after beginning treatment. (imaginis.com)
The study, 'Effects of Parathyroid Hormone (1-34) on Fractures and Bone Mineral Density in Post-Menopausal Women,' is published in the May 10, 2001 issue of the New England Journal of Medicine . (imaginis.com)
Physical training performed at a moderate or high intensity (aerobic or anaerobic) can reduce fatigue, improve quality of life, improve sleep quality, and increase bone mineral density in women survivors of breast cancer. (frontiersin.org)
Through blood tests and a variety of imaging tests conducted on equipment in the BBCL, including a dual energy X-ray absorptiometry scanner and peripheral quantitative computed tomography, UGA researchers will measure participants' bone mineral density and body composition. (scienceblog.com)
Stable bone density in adolescents with severe growth hormone deficiency after six months off rhGH. (galileo-training.com)
Hormone replacement therapy is required to achieve peak bone density in patients whose underlying pathology cannot be reversed to restore normal endocrine function. (medscape.com)
In conditions leading to estrogen deficiency, hormone replacement therapy is required to maintain bone density, and it may have other possible health benefits in patients whose underlying pathology cannot be reversed to restore normal endocrine function. (medscape.com)
One study investigated the therapeutic effect of supplementing vitamin D3 alone, vitamin K2 alone, and both combined on bone mineral density in postmenopausal women. (naturalproductsinsider.com)
5 The two-year study of 172 subjects found that the combined therapy significantly increased bone mineral density compared to either vitamin alone. (naturalproductsinsider.com)

Several injuries and health conditions can impact your cranial bones, including fractures and congenital conditions. (healthline.com)
People with this condition are more prone to fractures because the affected bone is usually weaker. (healthline.com)
Insufficient mineralization of the skeleton during growth leads to reduced peak bone mass and an increased risk of osteoporosis and fractures later in life. (gu.se)
And because the abnormal bone is weaker and more brittle than normal, it is prone to fractures. (mydr.com.au)
Evidence is mounting that loss of menstrual regularity, especially if related to hypogonadotropic hypogonadism, is a risk factor for later development of osteoporosis and hip fractures. (medscape.com)

Osteochondrodysplasia is a general term for a disorder of the development of bone and cartilage. (wikipedia.org)
16. Miller DM, Tarpley J. An automated double staining procedure for bone and cartilage. (trdizin.gov.tr)
Several therapeutic applications are developed in the field of bone and cartilage defect treatments, based on the osteoinductive and osteoconductive properties of these materials but also on the intrinsic physiological regenerative properties of bone [ 3 ]. (hindawi.com)
Sore joints or arthritis due to damage to the cartilage which lines the ends of bones. (mydr.com.au)

The aim of this case-control study (n = 30) was to evaluate the effects of osteoporosis/osteopenia on the success of dental implants. (allenpress.com)
Although 3 subjects with osteoporosis had treatment with oral bisphosphonates, no side effects were noted and no bone necrosis of the jaw was observed. (allenpress.com)
A new drug called Forteo (generic name, teriparatide) may soon be the first FDA approved drug that actually helps form new bone in patients with osteoporosis , a degenerative bone disease. (imaginis.com)
If parathyroid hormone treatment [Forteo] receives approval for osteoporosis from the Food and Drug Administration (FDA), it would be the first treatment option to build substantial amounts of bone by increasing bone formation,' said Dr. Johnston. (imaginis.com)
Osteoporosis is a degenerative bone disease that affects primarily post-menopausal women. (imaginis.com)
It helps reduce the risk of osteoporosis and bone fracture. (vbox7.com)
Childhood cancer survivors (CCS) are at risk of reduced bone health and premature osteoporosis. (galileo-training.com)
In other cases, correcting the underlying pathology should restore normal ovarian endocrine function and prevent the development of osteoporosis. (medscape.com)
Effects of Vitamin K2 on the Development of Osteopenia in Rats as the Models of Osteoporosis. (naturalproductsinsider.com)

Journal of Bone and Mineral Metabolism. (wikipedia.org)
Based on the finding that alcohol alters the circulating levels of dozens of peptides shown to influence bone metabolism, we arrive at the conclusion that no single unifying mechanism adequately explains the diversity of reports or successfully predicts individuals most likely to be impacted favorably or unfavorably by alcohol consumption. (springer.com)
Hematopoietic Stem Cell and Leukaemic Stem Cell environmental stress responses (In vitro biomimicry of hypoxia, normoxia, hypothermia, hyperthermia, hypoglycemia and hyperglycemia): Effect on cellular growth, cell cycle distribution, apoptosis and cellular metabolism. (imperial.ac.uk)
Functional coupling between these two cell types is critical for the maintenance of proper bone metabolism, and the mechanisms controlling the transition from bone-resorbing to bone-forming phases have been investigated. (sciencedaily.com)
EMFs are known to affect bone metabolism and muscle tissue. (stopumts.nl)

Results indicated a significant reduction in ovulation and implantation efficiency from exposure to higher concentrations and slightly retarded fetal development at both concentrations. (cdc.gov)
Fetal exposure to lead can adversely affect neurodevelopment, decrease fetal growth, and increase the risk for premature birth and miscarriage ( 1 ). (cdc.gov)

With the objective of investigating the effects on longitudinal bone growth rate (LGR), body weight (BW), and GH release, ipamorelin in different doses (0, 18, 90 and 450 microg/day) was injected s.c. three times daily for 15 days to adult female rats. (nih.gov)
9. Mizrak S, Turan V, Caglayan O, Ercan G. The effect of long term pre/postnatal low/high dose nicotine exposure on tissue oxidant/antioxidant status and DNA damage in rats. (trdizin.gov.tr)
Development of Forteo was suspended in 1998 after rats who were given lifelong doses of Forteo developed bone cancer. (imaginis.com)
In conclusion, 3.5 GHz RFR may have potential to alter bone quality and structural integrity including muscle oxidative stress parameters in rats. (stopumts.nl)
In this study, published in the journal Nutrients , researchers investigated the effects of polyphenol resveratrol (RES) in preventing bone defects in rats caused by methotrexate (MTX), a commonly used antimetabolite in childhood oncology. (nutraingredients.com)
The Roles of Chemokine CXCL13 in the Development of Bone Cancer Pain and the Regulation of Morphine Analgesia in Rats. (bvsalud.org)
The aim of this study was to investigate whether chemokine (C-X-C motif) ligand 13 (CXCL13) and its receptor ( C-X-C chemokine receptor type 5, CXCR5) involve in the development of bone cancer pain (BCP) and the regulation of morphine analgesia in rats . (bvsalud.org)

A fracture refers to any type of break in a bone. (healthline.com)
A linear fracture in a cranial bone means there's a break in the bone, but the bone itself hasn't moved. (healthline.com)

Maurel DB, Boisseau N, Benhamou CL, Jaffre C. Alcohol and bone: review of dose effects and mechanisms. (springer.com)
Bone formation represents a heritable trait regulated by many signals and complex mechanisms. (nature.com)
Exploration of genes that cause SBD has significantly improved our understanding of the mechanisms that regulate bone formation. (nature.com)
In this study, we explore different signaling pathways and associated molecular mechanisms of underlying primary breast cancer development, along with the formation of metastases in the bone. (degruyter.com)
RES, a naturally-occurring molecule, has been identified to have moderate protective effects in optimising bone health including age-related bone loss despite the unclear mechanisms. (nutraingredients.com)
Vitamin D and bone health: potential mechanisms. (naturalproductsinsider.com)
Within the field of genetics, Charité's main areas of research focus include the identification and analysis of disease mechanisms, biocomputational analysis, the analysis and linking of clinical symptoms (phenotype) with genetic variants, as well as the development of genetic testing sys-tems and their implementation in clinical practice. (charite.de)

A three-dimensional finite element model of the lower first premolar, with the three layers of enamel, dentin, and pulp, and the mandible, with the two layers of cortical and cancellous bones, was directly constructed from noninvasively acquired CT images. (hindawi.com)

Pathway-based biomarkers identification may help elucidate the cellular signature of breast cancer metastasis in bone, further characterizing the etiology and promoting new therapeutic approaches. (degruyter.com)
These differences affect the progression of cancer and how it responds to therapeutic agents and their ultimate efficacy. (degruyter.com)
Monitor for decreased therapeutic effects of penicillins if concomitantly used with a tetracycline. (medscape.com)
In therapeutic clinical trials, bone scan is the standard imaging modality to assess eligibility and progression for patients with metastatic prostate cancer. (snmjournals.org)
Currently, therapeutic approaches to successfully prevent or control bone loss caused by MTX chemotherapy are still lacking. (nutraingredients.com)

The results showed that RFR exposure had adverse effects on bone biomechanics, including decreased elasticity coefficient and Young's modulus, increased maximum displacement and decreased maximum force. (stopumts.nl)
Does caffeine have any adverse effects? (medicalnewstoday.com)

Immature B cells from normal mouse bone marrow were not responsive to the suppressive effect of androgens unless they were cocultured with marrow stromal cells or with supernatants from androgen-treated stromal cells, suggesting that the androgen effects are exerted through marrow stromal elements by production of a diffusible mediator. (jci.org)
The aim of this study was to examine the effects of continuous treatment with CT on the generation of osteoclasts and calcitonin receptor (CTR) expression in mouse bone marrow cultures. (edu.au)
This was done by daily CT treatment of mouse bone marrow cultures from day 0, when only undifferentiated mononuclear precursors of osteoclast-like cells were present, or commencing from day 6, when differentiated osteoclast-like cells were abundant. (edu.au)

Several diseases can result in disorders of bone mineralization, which can be defined as the process by which osteoid becomes calcified. (medscape.com)
The protein and bioactive compounds in eggs, such as lutein and zeaxanthin, are thought to be advantageous to bone mineralization in children during growth," said Richard Lewis , UGA Foundation Professor in the department of foods and nutrition and principal investigator of the study. (scienceblog.com)

Since implants are standard sizes, periapical bone loss was measured from the first implant thread to the level of alveolar bone at baseline, 12 months, and 24 months via 1 periapical radiograph. (allenpress.com)
Tezal 13 suggests systemic bone loss is related to alveolar bone loss, and to a lesser extent, clinical attachment loss in postmenopausal Caucasian women. (allenpress.com)

Histological analyses revealed a neoformed bone with regular trabecular structure, areas of mineralized bone inside the membrane, and an improved neovascularization in the treated lesion with bifunctionalized membrane. (hindawi.com)
However, the current study demonstrated a significantly reduced growth plate thickness, shorter primary spongiosa height, reduced trabecular bone volume, as well as increased marrow adiposity following acute MTX treatment. (nutraingredients.com)

A total of 61 DEGs, included 27 down-regulated and 34 up-regulated, were found to be significant in breast cancer bone metastasis. (degruyter.com)
DEGs Bcl3, ADGRG7, FABP4, IRF4, their regulating miRNAs and TFs have strong impact on proliferation and metastasis of breast cancer in bone tissues. (degruyter.com)
In conclusion, present study revealed that DEGs are directly involved in of breast tumor metastasis in bone tissues. (degruyter.com)
Metastasis to bone typically results in a poor prognosis, reducing life expectancy to 2-3 years post-diagnosis. (degruyter.com)
In clinical routine, bone scan is the most common imaging modality to monitor bone metastasis. (snmjournals.org)
Background: Osteodex (ODX) is a cytotoxic bone-targeting polybisphosphonate, intended for treatment of bone metastasis from castration-resistant prostate cancer (CRPC). (lu.se)
Patients and Methods: Twenty-eight patients with castration-resistant prostate cancer and confirmed bone metastasis were assigned to seven infusions of ODX every third week, divided in seven ascending dose cohorts. (lu.se)

Based on these data, we suggest that the 'escape' phenomenon may result from a prolonged CT-induced loss of CT responsiveness due, at least in part, both to reduced synthesis of CTR, and to the appearance in bone of CTR-deficient osteoclasts. (edu.au)
New bone tissue is rapidly made due to unusual behavior of osteoclasts, which are a type of bone cell. (healthline.com)
During this "remodeling" process, osteoclasts remove mineralized bones, whereas osteoblasts form new bones. (sciencedaily.com)
Using this method, they explored the interplay between bone-destroying osteoclasts and bone-forming osteoblasts. (sciencedaily.com)
Osteoclasts , which break down and remove old bone. (mydr.com.au)
The osteoclasts become over-active, which means they break down more bone than normal. (mydr.com.au)

Its abnormalities manifest themselves in various diseases, including sclerosing bone disorder (SBD). (nature.com)
Future research planned includes characterizing the interplay between lymphatic flow and transport diseases that affect the lymphatic system. (umass.edu)
The osteoblast communication via extracellular vesicles controls the dynamic transition from bone-forming to bone-resorbing phases in vivo and could be a target for new treatments for bone diseases. (sciencedaily.com)
The clinical purpose of these methods is the reparation or guided regeneration of damaged tissue, in our case, jaw bone affected by genetical diseases. (hindawi.com)

Pathogenic variants in the patients impair the TMEM53-mediated blocking effect, thus leading to overactivated BMP signaling that promotes bone formation and contributes to the SBD phenotype. (nature.com)
Wild-Type (WT) and Tabby (Ta) mice were used to compare effects on a normal phenotype and on a mutant model of ectodermal dysplasia (ED). After 21 days, no effect on bone neoformation was observed in Ta treated lesion (4% neoformation compared to 13% in the control lesion). (hindawi.com)
In conclusion, PCL functionalized biomembrane promoted bone neoformation, this effect being modulated by the Ta bone phenotype responsible for an alteration of bone response. (hindawi.com)

Paget's disease is a treatable condition that affects the bones, mainly in older people. (mydr.com.au)
Any bone in the body can develop Paget's disease, but it particularly affects the skull, spine, pelvis, legs and arms. (mydr.com.au)
To understand Paget's disease, it's useful to learn more about the processes going on in your bones that help them stay healthy. (mydr.com.au)
But sometimes - like in Paget's disease - the balance of bone remodelling is upset. (mydr.com.au)
Bones affected by Paget's disease can also be painful. (mydr.com.au)
Paget's disease mainly affects older people. (mydr.com.au)
The symptoms of Paget's disease depend on where in the body the abnormal new bone is being produced. (mydr.com.au)
Less commonly, Paget's disease can affect the heart, because the abnormal new bone needs its own blood supply. (mydr.com.au)
A very rare complication in less than 1% of people with Paget's disease is the development of bone cancer in the abnormal bone. (mydr.com.au)
If you have unexplained pain in your bones, or if you have noticed changes in any of the bones in your body (including a change in the shape of your head), ask your doctor about Paget's disease. (mydr.com.au)

Honey is a natural product known for its varied biological or pharmacological activities-ranging from anti-inflammatory, antioxidant, antibacterial, antihypertensive to hypoglycemic effects. (mdpi.com)
anti obesity and hypoglycemic effects. (researchgate.net)

The stromal cell requirement for androgen-mediated effects was confirmed in vivo by experiments using chimeric animals created by bone marrow transplantation in which androgen receptor expression was restricted to either the stromal or lymphoid cells of the bone marrow. (jci.org)
In a study from the United States, long-term survivors of pediatric bone marrow transplantation followed in the Bone Marrow Transplant Survivors Study were compared with survivors of childhood cancer treated without bone marrow transplant from the Childhood Cancer Survivor Study. (medscape.com)
[ 2 , 8 ] Survivors of bone marrow transplantation were more likely to have a severe or life threatening condition (relative risk [RR] = 3.9), more than one chronic condition (RR = 2.6), functional impairment (RR=3.5), and activity limitations (RR = 5.8) than conventionally treated patients. (medscape.com)
These data reinforce the need for marked vigilance in ensuring proper screening and management of long-term survivors of bone marrow transplantation. (medscape.com)

Bone mass is aquired during childhood and adolescence, with peak bone mass reached between the ages of 20 and 30. (gu.se)

Several factors regulate bone formation, with nutrition being a crucial one," says Anna Svedlund, pediatrician at Queen Silvia Children's Hospital. (gu.se)
Bone cells respond to mechanical forces that regulate pathways involved in new bone deposition. (umass.edu)
Androgens regulate the development of the embryo, determining whether it is a male or a female (male in the presence of androgens and female in the absence of androgens). (encyclopedia.com)

Our in vivo and in vitro studies are elucidating biomolecular pathways involved in new bone deposition. (umass.edu)
Body hair, fat deposition, bone and muscle growth, and some brain functions are also influenced. (encyclopedia.com)
1 The calcium paradox involves the displacement of calcium in blood vessel walls with a simultaneous reduction of the deposition of calcium in the bones. (naturalproductsinsider.com)

As a result of new abnormal bone being produced, affected bones become enlarged and misshapen. (mydr.com.au)
Pain, numbness, weakness or paralysis in different parts of the body, due to the abnormal bone pressing on or pinching nerves in the spinal cord. (mydr.com.au)

Forteo is identical to a portion of the human parathyroid protein, a hormone responsible for bone formation. (imaginis.com)
Osteocalcin and matrix Gla protein (MGP) are two proteins that may negate these undesirable effects. (naturalproductsinsider.com)

bone from the femora of birds is not significantly affected by induced hypothyroidism, however, there is a strong positive relationship between the levels of circulating thyroid hormones and the mechanical properties of bone from humeri. (reading.ac.uk)
CONCLUSION: Based on the above-mentioned measurements, it may be concluded that masticatory hypofunction induced by a powdered diet affected mandibular morphology and was associated with significantly reduced bone content. (bvsalud.org)

Our results establish a previously unreported SBD entity (craniotubular dysplasia, Ikegawa type) and contribute to a better understanding of the regulation of BMP signaling and bone formation. (nature.com)
Its function remains unclear, particularly in bone formation. (nature.com)
Our findings establish a previously unreported SBD entity and demonstrate a regulatory mechanism in the BMP signaling pathway that impacts bone formation and development. (nature.com)
Now, researchers at Osaka University established an advanced high-resolution microscopy system to visualize extracellular vesicles secreted and captured by mature osteoblasts in vivo and identified a subset of osteoblast-derived vesicles limiting bone formation and stimulating bone-resorbing osteoclast differentiation through a microRNA (miRNA)-mediated mechanism. (sciencedaily.com)
2 Osteocalcin is secreted by osteoblasts-the cells responsible for bone formation-and promotes the formation of the essential components of the bone to ensure rigidity and strength. (naturalproductsinsider.com)

Antioxidant role of melatonin against nicotine's teratogenic effects on embryonic bone development. (trdizin.gov.tr)
2006. The effects of diazinon on lipid peroxidation and antioxidant enzymes in rat heart and ameliorating role of vitamin E and vitamin C. Cell Biol Toxicol 22(6):455-461. (cdc.gov)
Zinc - Helps boost the ANTIOXIDANT effects of coffee, giving FERN Coffee drinkers better protection from stress. (vbox7.com)

KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)" (PDF). (wikipedia.org)
However, all but 2 percent of fetuses affected by the disorder are miscarried. (encyclopedia.com)
Impact of a multimodal exercise program on tibial bone health in adolescents with Development Coordination Disorder: an examination of feasibility and potential efficacy. (galileo-training.com)
OBJECTIVES: Developmental coordination disorder (DCD) compromises bone health purportedly due to lower levels of physical activity. (galileo-training.com)
For the adolescent girl, a reproductive disorder impacts her developing sense of self, body-image, and sexuality, which, in turn, can affect her self-esteem and relationships with others. (medscape.com)

Breast cancer metastases are most commonly found in bone, an indication of poor prognosis. (degruyter.com)
Bone cancer metastases usually occur in the axial skeleton, in areas with active hematopoiesis and high red marrow content. (degruyter.com)

Your cranial bones are held together by unique joints called sutures, which are made of thick connective tissue. (healthline.com)
This causes the development of scarlike tissue instead of bone tissue due to a mutation in bone-producing cells. (healthline.com)
Bone regeneration using electrospun nanofibers' implant has the following objectives: bone neoformation induction with rapid healing, reduced postoperative complications, and improvement of bone tissue quality. (hindawi.com)
Thus, the strategy of functionalization of nanofibers by nanoreservoirs of BMP-2 or BMP-7 showed a great efficiency for bone regeneration and increased the differentiation of MSCs (mesenchymal stem cells), accelerating the tissue regeneration in vivo [ 9 , 10 , 13 , 14 ]. (hindawi.com)
The second group was monitored for toxic effects and incidence, size, and location of tissue masses. (cdc.gov)

Detrimental effects of alcohol on bone growth. (springer.com)
Inadequate nutrition can negatively impact bone mass and growth. (gu.se)
Early puberty can also cause problems with bone growth. (webmd.com)

Hormones can be inadequate during or after each stage of development - embryonic and adolescent. (encyclopedia.com)

Bone remodeling occurs in different parts of the body throughout life to maintain bone architecture balance and systemic mineral homeostasis. (sciencedaily.com)
Estrogen and testosterone help to maintain bone mass and strength and may protect the cardiovascular system . (encyclopedia.com)

We have demonstrated that fluid flow serves as a physical stimulus inducing expression of genes required for lymphatic valve development and identified a novel role for GATA2, an upstream transcriptional regulator of FOXC2. (umass.edu)
They also showed that vitamin D had a significant effect on the activity of 229 genes including IRF8, previously associated with MS, and PTPN2, associated with Crohn's disease and type 1 diabetes. (sciencedaily.com)
New techniques have been developed that allow researchers to recreate genetic changes affecting human genes within the mouse genome. (charite.de)

16 , 17 Postmenopausal women 18 are at greater risk for mandibular bone mineral content loss than older men. (allenpress.com)
AIM: This experimental study investigated the association between masticatory hypofunction and mandibular morphological dimensions and internal bone characteristics. (bvsalud.org)

A bone disease is also called an "osteopathy", but because the term osteopathy is often used to refer to an alternative health-care philosophy, use of the term can cause some confusion. (wikipedia.org)
Effect of tobacco control policies on perinatal and child health: A systematic review and meta-analysis. (trdizin.gov.tr)
Alcohol consumption is often reported to influence bone health in a dose-dependent manner where moderate alcohol intake is deemed beneficial and heavy drinking detrimental. (springer.com)
Vitamin D supplements during pregnancy and the early years could have a beneficial effect on a child's health in later life. (sciencedaily.com)
in pregnant mothers, poor bone health can be fatal to both mother and child at birth, hence there are selective pressures in favour of people who are able to produce adequate vitamin D. (sciencedaily.com)
It works with Calcium for optimum BONE HEALTH. (vbox7.com)
It is one in a series of Public Health Statements about hazardous substances and their health effects. (cdc.gov)
This public health statement tells you about chloroethane and the effects of exposure. (cdc.gov)
By using software developed by the National Institutes of Health, the UGA researchers can assess whether egg consumption has an effect on children's brain health. (scienceblog.com)
While bone and brain function are rarely studied together, obesity-a global epidemic-has been shown to diminish both bone and brain health due to chronic inflammation. (scienceblog.com)
High Impact Physical Activity and Bone Health of Lower Extremities in Childhood Cancer Survivors: A Cross-sectional Study of SURfit. (galileo-training.com)
Primary amenorrhea and the potential for impaired fertility affect the emotional health of the adolescent and her family. (medscape.com)
However, one of the major health threats associated with these effective chemotherapy regimens is the irreversible detrimental effects on bone. (nutraingredients.com)
The intake of calcium, whether through diet or supplementation, has historically been linked to bone health. (naturalproductsinsider.com)
Vitamin D3, a nutrient well-known for its role in bone health, 3 increases the production of inactive osteocalcin and MGP. (naturalproductsinsider.com)
To read this article in its entirety-along with other coverage of the category-check out "The role of vitamins K2 + D3 in bone health" in the " Joint and bone health to maximize movement " digital magazine. (naturalproductsinsider.com)
Beneficial effects of UV radiation include the production of vitamin D, a vitamin essential to human health. (cdc.gov)
several medications also contained mercury or arsenic, which also can have adverse health effects. (cdc.gov)
Taufiq Mashal, Director General of Preventive Medicine and Primary Health Care and Dr. Zarmina Safi, Head of Public Nutrition Department of MoPH for their continued support and guidance throughout the strategy development process. (who.int)
One in three of the world's people suffer from hidden hunger (vitamin and mineral deficiencies), needed for survival, development, health and a productive life. (who.int)
Cindy Hinton is a health scientist in the disability and health branch in the division of human development and disability at the Centers for Disease Control and Prevention. (cdc.gov)
Because of the complications associated with chronic haemoglobin disorders and the consequent years of disability, haemoglobinopathies are becoming a growing health-care problem in all affected regions but in particular the developing world. (who.int)

In addition to complications seen from exposure to chemotherapy and radiation, patients undergoing allogeneic transplantation can experience unique late effects secondary to graft versus host disease (GVHD) and autoimmunity. (medscape.com)
To stimulate and facilitate further research, the NCI and NHLBI held the First International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation on April 28 and 29, 2011. (medscape.com)

Resveratrol is a potential candidate to help prevent bone-related complications in children during and after chemotherapy, a study carried out by Australian and Chinese academics claims. (nutraingredients.com)
RES is suggested to be a potential candidate for the development of preventative strategies to prevent the bone-related complications during and/or after MTX chemotherapy. (nutraingredients.com)

Conclusion: Nicotine use negatively affects the morphological development of the embryo. (trdizin.gov.tr)
Conclusion: ODX was well tolerated, with few and mild side-effects and with apparent treatment efficacy in the highest dose cohort. (lu.se)

The tumor cell mass exerts mechanical pressure that can contribute to bone pain. (degruyter.com)
The microenvironment is fundamental in attracting tumor cells to the bone as well as promoting tumor progression. (degruyter.com)
The composition of the tumor microenvironment changes during tumor development, evolving to meet the demands of the growing neoplasm [ 6 ]. (degruyter.com)

We employed in vitro cultures and two in vivo models to investigate whether androgens exert these effects directly on marrow lymphoid precursors or whether actions on marrow stromal elements are required. (jci.org)
To understand the spatiotemporal dynamics of bone remodeling in vivo , the researchers have established an intravital imaging technique to visualize the intact bone tissues of living mice. (sciencedaily.com)
In vivo implantation of polycaprolactone (PCL) biomembrane functionalized with BMP-2/Ibuprofen in mouse maxillary defects was followed by bone neoformation kinetics evaluation using microcomputed tomography. (hindawi.com)

Pre-natal and early post-natal development were uneventful, but all five showed proportional or short-limbed short stature with variable severity, which was not identifiable at birth (Table 1 ). (nature.com)

Fucosidosis is a condition that affects many areas of the body, especially the brain. (medlineplus.gov)

Kallman's syndrome (KS) is the most frequent cause of hypogonadotropic hypogonadism and affects approximately one in 10,000 males and one in 50,000 females. (encyclopedia.com)

The bones and lungs may be affected less frequently ( 1 ). (cdc.gov)

Dec. 20, 2022 In our bones, specialized cells called osteoblasts are responsible for building up bone substance. (sciencedaily.com)

Researchers show that intercellular communication via extracellular vesicles from bone-making osteoblasts is a key factor for this switch through a microRNA-mediated mechanism. (sciencedaily.com)
Researchers at the University of Georgia want to know if eating eggs can improve bone strength and cognitive function in obese and normal weight children between the ages of 9 and 13 years old. (scienceblog.com)

Body movements drive interstitial fluid flow potentially stimulating bone cells. (umass.edu)
The part of the body where they get the shot or implant may hurt a bit, or their skin might get irritated around that spot, but there don't seem to be any long-term side effects. (webmd.com)
Learn more about caffeine and its effects on the body here. (medicalnewstoday.com)
We should have a pretty good model to answer the question about how egg intake influences bone and cognition," said Lewis, who also serves as director of UGA's Bone and Body Composition Lab . (scienceblog.com)
Vitamin D helps the body absorb calcium and phosphorus from food and assists bone development. (cdc.gov)

This data suggests that combination usage of MTX with RES at 10 mg/kg dose further aggravate the MTX bone damage effect. (nutraingredients.com)
At the lower dose, however, RES supplementation demonstrated protective effects against MTX-induced bone damage. (nutraingredients.com)
However, RES supplementation demonstrated protective effects against MTX-induced bone damage in this rat model study. (nutraingredients.com)
Damage to bone marrow and spermatogonial cells occurred at both exposure concentrations. (cdc.gov)
In addition to renal disease, cardiovascular effects, and reproductive toxicity, lead may cause irreversible neurologic damage. (cdc.gov)
The increased occurrence of microcephaly associated with cerebral damage characteristically seen in congenital infections in Zika virus-affected areas is suggestive of a possible relationship. (cdc.gov)

Vitamin B1 is essential for the nervous and cardiovascular system development ✅Vitamin D3 - Helps in enhancing the IMMUNE SYSTEM. (vbox7.com)
These events may have clinical consequences, affecting areas such as the cardiovascular and musculoskeletal systems. (naturalproductsinsider.com)

Objectives: The aim of this experimental rat study was to investigate the effectiveness of vitamin B12 (Vit-B12) against the teratogenic effects of nicotine use during pregnancy in the fetus. (trdizin.gov.tr)
4 However, equally important is vitamin K2, which is required to activate the proteins, and in doing so, plays a pivotal role in moving calcium to the bones and removing it from blood vessels. (naturalproductsinsider.com)

In mammals, pythiosis is characterized by the development of cutaneous and subcutaneous abscesses and intestinal necrotic lesions. (cdc.gov)
Between the 21st and the 30th days, the use of biomembrane functionalized with BMP-2/Ibuprofen in maxillary bone lesions allowed a significant increase in bone neoformation peaks (resp. (hindawi.com)

In severe cases, symptoms typically appear in infancy, and affected individuals usually live into late childhood. (medlineplus.gov)
We investigated the effect of nutritional treatment on bone development in young women with severe anorexia nervosa. (gu.se)

Since the first large cohort of patients was cured in the 1970s, much has been learned about the long-term effects of exposure to chemotherapy, radiation, and surgery in childhood. (medscape.com)
[ 4 , 5 ] The late effects of exposure to chemotherapy, radiation and surgery make the care of survivors highly complex and mandate structured, coordinated long-term follow-up. (medscape.com)
The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. (cdc.gov)
Sunburn is a sign of short-term overexposure, while premature aging and skin cancer are side effects of prolonged UV exposure. (cdc.gov)

X-rays help find out if your child's bones are maturing too early. (webmd.com)

Androgens only affected B cell development in chimeric mice with androgen-sensitive stromal cells. (jci.org)
These experiments suggest that effects of androgens on developing B cells are mediated through androgen receptors in bone marrow stromal cells. (jci.org)
Androgens also exert effects on B cell development in bone marrow. (jci.org)

During each stage, inadequate hormone stimulation will prevent normal development. (encyclopedia.com)

He's been with the newspaper since 2018 and enjoys diving into complex stories that affect people's lives. (ajc.com)

Affected bones become enlarged, misshapen and weaker than normal. (mydr.com.au)

Anatomy59

Organisms7

Diseases36

Chemicals and Drugs77

Analytical, Diagnostic and Therapeutic Techniques and Equipment33

Phenomena and Processes40

Disciplines and Occupations1

Technology, Industry, Agriculture4

Information Science2

Health Care9

Geographicals1

Resorption10

Skeletal12

Density23

Fractures5

Cartilage4

Osteoporosis9

Metabolism5

Fetal2

Rats7

Fracture2

Mechanisms7

Cortical1

Therapeutic5

Adverse effects2

Mouse bone marrow3

Mineralization2

Alveolar bone2

Trabecular2

Metastasis7

Osteoclasts6

Diseases4

Phenotype3

Paget's10

Hypoglycemic effects2

Marrow transplantation4

Childhood and adolescence1

Regulate3

Deposition3

Abnormal bone2

Protein2

Significantly2

Formation5

Antioxidant3

Disorder5

Metastases2

Tissue5

Growth3

Embryonic1

Maintain bone2

Genes3

Mandibular2

Health22

Transplantation2

Complications2

Conclusion2

Tumor3

Vivo3

Post-natal development1

Condition that affects1

Hypogonadotropic hypogonadism1

Lungs1

20221

Researchers2

Body5

Damage6

Cardiovascular2

Vitamin2

Lesions2

Severe2

Exposure4

Child's1

Androgens3

Hormone1

20181

Weaker1