• The biological activity of propolis is associated mainly with phenolic compounds such as flavonoids and derivatives of hydroxycinnamic acids. (scirp.org)
  • The aim of the literature review was to summarize recent studies from the PubMed database evaluating the antiviral activity of propolis extracts in terms of prevention and the therapy of respiratory tract diseases (in vitro, in vivo, clinical trials). (propolisscience.org)
  • Differences in the chemical composition lead to diversity in biological activity of propolis samples. (blogspot.com)
  • The differences between in vitro and in vivo trypanocidal activity of propolis and future perspectives are discussed. (propolisscience.org)
  • Microencapsulation experiments were carried out by investigating the effect of sample/solvent ratio (10-100 mg mL −1 ), poly(ε-caprolactone) (PCL) concentrations (200-1,000 mg mL −1 ), poly(vinyl alcohol) (PVA) concentrations (0.5-2.5 g mL −1 ), and stirring speed (200-1,000 r.p.m.) on the microencapsulation efficiency of total phenolic content (TPC%) and antioxidant activity of propolis. (akjournals.com)
  • The objectives of the present study were to evaluate the effect of standardized Brazilian propolis extract (P1) on response to histamine cumulative-concentration contraction on guinea pig isolated trachea in vitro, on the oedema induced by histamine in mice, and to evaluate the effect of P1 on ulceration in mice's stomach treated with sodium diclofenac. (scirp.org)
  • The composition, colour, and properties of propolis vary from region to region, depending on the type of plants, flowers, and trees used to make propolis. (bellyfatlossguru.com)
  • The properties of propolis may be important in the prevention and treatment of respiratory tract diseases caused by viruses such as severe acute respiratory syndrome coronavirus 2, influenza viruses, the parainfluenza virus and rhinoviruses. (propolisscience.org)
  • Occupational contact dermatitis may also be caused by airborne propolis emitted from nearby hives. (medscape.com)
  • Patch-test reactions to propolis, allergen LB-1, and balsam of Peru were all positive, suggesting that the patient was reacting to an "odorous cloud" that was emitted from the hives, and his symptoms resolved upon avoidance. (medscape.com)
  • Caffeic acid phenethyl ester (CAPE), an active ingredient in propolis obtained from honeybee hives, is known to have antitumor, immunomodulatory, anti-inflammatory, and antioxidant properties. (beeandyou.com)
  • Dr. Ohhira's Propolis PLUS® is AVA Vegetarian certified and combines a unique and consistently potent Brazilian green propolis with Flax Oil, Omega-3, antioxidant support from Vitamin E and Astaxanthin, and Dr. Ohhira's world-renowned probiotic extract. (naturalmedicinejournal.com)
  • The composition of a Brazilian green propolis ethanolic extract (Et-Bra) and its effect on Trypanosoma cruzi trypomastigotes and other pathogenic microorganisms have already been reported. (fiocruz.br)
  • They fed some 'old' mice different doses of green propolis for 4 weeks. (bee-pollen-buzz.com)
  • To evaluate the effect of 4 different levels of propolis supplementation on the hematological and immunological parameters of laying hens, a trial was conducted with 60 White Leghorn layer hens. (erciyes.edu.tr)
  • In addition, the level of 3 g/kg of propolis supplementation significantly increased (P (erciyes.edu.tr)
  • On the other hand, hemoglobin and hematocrit values and total leucocyte (white blood cells) and differential leucocytes counts were not influenced by propolis supplementation. (erciyes.edu.tr)
  • Afsharpoura F, Hashemipourc S, Koushand Y, Khadem haghighiana H. Propolis supplementation improves glycemic and antioxidant status in patients with type 2 diabetes: A randomized, double-blind, placebocontrolled study. (ac.ir)
  • Effects of synbiotic supplementation on gut microbiome, serum level. (yasni.de)
  • Effect of curcumin-pipeine supplementation on clinical status, mortality rate, oxidative stress, and inflammatory markers in critically ill ICU patients with COVID-19: a structured summary of a study protocol for a randomized controlled trial. (cdc.gov)
  • The effect of propolis supplementation on clinical symptoms in patients with coronavirus (COVID-19): A structured summary of a study protocol for a randomised controlled trial. (cdc.gov)
  • Propolis seems to help fight against bacteria, viruses, and fungi. (medlineplus.gov)
  • Propolis also shows anti-microbial properties against bacteria, fungi, and protozoans. (bellyfatlossguru.com)
  • Propolis always thrives in protecting the mucuous linings of the body from bacteria, viruses, fungi, inflammation and even tumor cell growth. (blogspot.com)
  • the antibiotic resistant bacteria that is affecting many hospitals. (infiniteunknown.net)
  • Additionally, levels of MDA, lactic acid, TVB-N, count of psychrophilic, and mesophilic bacteria in cypermethrin+propolis treated groups were significantly reduce in comparison to exposed groups with cypermethrin (P (ac.ir)
  • Consequently, this propolis underwent fractionation by chromatographic methods monitored through Agar-diffusion assays with these bacteria, which resulted in the isolation and identification of 3,5-diprenyl-4-hydroxycinnamic acid (artepillin C), which showed MIC of 62.5 and 250 µg/mL against B. subtilis and S. aureus, respectively. (scielo.br)
  • Propolis extract, on the other hand, helps prevent infection by killing bacteria and other microorganisms on the skin's surface. (love.com)
  • Propolis extract acts as a natural antiseptic, preventing bacteria and other microorganisms from causing infections on sunburned skin. (love.com)
  • Propolis seems to work against disease-causing bacteria in at least two ways: preventing reproduction and breaking down bacterial membranes. (betternutrition.com)
  • The anti-viral effect is observed not only with extracts but also with the single biologically active compounds found in propolis (e.g., apigenin, caffeic acid, chrysin, kaempferol, quercetin). (propolisscience.org)
  • Although its chemical composition varies, propolis constituents generally include about 10% essential oils, 5% pollen, and 15% various organic polyphenolic compounds including flavonoids and phenolic acids. (hindawi.com)
  • In another study, scientists exposed the well known H1N1 virus to Propolis compounds in a lab setting and found strong evidence that propolis has an anti-influenza effect. (bee-pollen-buzz.com)
  • According to the researchers, the compounds within propolis that demonstrate the anti-flu properties are called caffeoylquinic acids. (bee-pollen-buzz.com)
  • Besides traditional synthetic compounds, many natural products were found to exert anticancer effects. (hindawi.com)
  • The aim of this work was to microencapsulate propolis phenolic compounds using polycaprolactone as wall material by double emulsion solvent evaporation (w 1 /o/w 2) . (akjournals.com)
  • Natural agents including compounds as resveratrol, puerarin, curcumin, hesperidin and silymarin, and extracts of propolis, Lycopus lucidus , and Momordica charantia have been shown to combat diabetes via modulation of TGF-β signaling pathway. (frontiersin.org)
  • Some 300 different compounds have been identified in propolis, including resveratrol. (betternutrition.com)
  • Results suggested also, at least in part, the antiulcerogenic effect of formulation containing standardized extract of propolis can be due to the antagonistic action on the histaminergic system. (scirp.org)
  • Mycobacterium tuberculosis (H37Rv)-infected guinea-pig model was used to investigate the effect of water extract of propolis (WEP). (anadolu.edu.tr)
  • The study found that while the propolis extract samples from China did not have a significant effect, Anatolian propolis extract from Turkey showed a higher phenolic component content and had the potential to suppress breast cancer cells more effectively than other propolis samples. (beeandyou.com)
  • To evaluate in vitro the effect of a red propolis ethanolic extract (RPE) in the prevention of growth of a cariogenic biofilm and its cytotoxic potential. (bvsalud.org)
  • Recently, an increasing number of studies are focusing on the activity of various propolis preparations against SARS-CoV-2 as an adjuvant treatment for this infection. (propolisscience.org)
  • A Scientific study says that: According to scientific research conducted at Istanbul University in 2019, which examined the phenolic contents of various propolis extract samples and their effects on breast cancer cells, the suppressive effects of propolis on breast cancer cells varied depending on the amount and types of phenolic components of each sample. (beeandyou.com)
  • The antiviral effect of propolis extracts and selected constituents, e.g. caffeic acid (1), p-coumaric acid (2), benzoic acid (3), galangin (4), pinocembrin (5) and chrysin (6) against herpes simplex virus type 1 (HSV-1) was analysed in cell culture. (nih.gov)
  • In addition, the flavonoid chrysin in propolis helps reduce renal injuries in the kidney and protects the structures of the kidney from harm. (bellyfatlossguru.com)
  • Aqueous and ethanol extracts of propolis were analysed phytochemically and examined for their antiviral activity in vitro. (nih.gov)
  • The 50% inhibitory concentration (IC(50)) of aqueous and ethanol propolis extracts for HSV-1 plaque formation was determined at 0.0004% and 0.000035%, respectively. (nih.gov)
  • Different doses of propolis ethanol extract were p.o. administered three times per day for three days, after four weeks' alcohol administration. (tmu.edu.tw)
  • It was found that 10 mg/kg of propolis ethanol extract significantly decreased the elevations of serum GOT, GPT, TG and HTG. (tmu.edu.tw)
  • In histopathological examination, 30 mg/kg of propolis ethanol extract also remarkably decreased the hepatocellular fatty degeneration, apparent as vacuolization, induced by chronic alcohol abuse. (tmu.edu.tw)
  • Applying an ointment or cream containing 0.5% to 3% propolis five times daily might help cold sores to heal faster and reduce pain. (medlineplus.gov)
  • You can take propolis as a supplement, mouthwash, or topical ointment on the skin. (bellyfatlossguru.com)
  • [ 73 ] Propolis-induced contact dermatitis can also mimic pemphigus vulgaris, which was the case in a patient who applied propolis-containing ointment and lip balm, resulting in blistering dermatitis of the lips and adjacent oral mucosa, leading to an initial misdiagnosis of pemphigus. (medscape.com)
  • An investigation of effectiveness of topical treatment of nonhealing chronic venous leg ulcers with propolis ointment was conducted. (hindawi.com)
  • In group 1, there were 28 patients (ulceration area: 6.9-9.78 cm 2 ) treated by means of topical propolis ointment application and short stretch bandage compression. (hindawi.com)
  • We found that an adjunctive propolis ointment treatment increases the efficacy of the short stretch bandage compression stocking, and this combined treatment is more effective than Unna's boot compression alone. (hindawi.com)
  • The main objective of this study is to investigate the use of propolis ointment in the treatment of chronic nonhealing venous leg ulcers. (hindawi.com)
  • Propolis is a resinous substance collected from trees by the bee Apis mellifera , which uses it as a building and insulating material in the hive. (hindawi.com)
  • Propolis is a natural resin used around the world to treatment of several diseases. (scirp.org)
  • Propolis is a natural resin. (bellyfatlossguru.com)
  • Propolis is a resin obtained from the buds of some trees and flowers. (healthy.net)
  • Propolis contains tree resin, essential oils, waxes and bioflavonoids. (uk.com)
  • The aim of this clinical trial was to test the efficacy of propolis as a mouthwash in the reduction of chemotherapy induced oral mucositis (OM) in a single center. (nih.gov)
  • Propolis was the second most studied intervention for mucositis (4 reviews) and dental plaque (3 reviews) outcomes. (bvsalud.org)
  • In this study, we report for the first time the antioxidant, cytotoxic, and antinociceptive activities of propolis from Bangladesh (BDP). (blogspot.com)
  • The antibacterial effects of six solutions on oral pathogen microorganisms were tested and their cytotoxic effects on human gingival fibroblasts were evaluated by MTT assay. (deu.edu.tr)
  • The effective dilutions of the six propolis samples on periodontopathogen microorganisms were found to be cytotoxic to gingival fibroblasts. (deu.edu.tr)
  • Propolis could have a promising role in the future medicine, if appropriate solutions can be prepared being strongly antibacterial and non-cytotoxic as well. (deu.edu.tr)
  • Propolis based preparations have a wide range of applications in various specialties of dentistry. (nih.gov)
  • Propolis which is a natural resinous product from the honeybees, is becoming increasingly popular for its diverse therapeutic and industrial applications. (blogspot.com)
  • Propolis is a waxy or resinous mixture made by honeybees. (bellyfatlossguru.com)
  • Propolis is a resinous hive product collected by honeybees from various plant sources. (blogspot.com)
  • Propolis, a natural resinous product, is collected from various plant sources by honeybees, which use it to seal holes in their honeycombs. (hindawi.com)
  • NaturalNews) Bee propolis is a remarkable natural substance collected and produced by honeybees. (infiniteunknown.net)
  • Propolis designates a mixture of gums, resins and balms, of viscous consistency, which are gathered on certain parts (buds and bark, mainly) of vegetables (especially coniferous trees) by honeybees. (tmu.edu.tw)
  • Propolis has anti-inflammatory properties that can help reduce inflammation in the body. (biolyphar.com)
  • The anti-inflammatory properties of aloe vera and propolis extract help reduce redness and swelling associated with sunburns. (love.com)
  • Use propolis with caution if you are allergic to bee byproducts. (medlineplus.gov)
  • The first report of a case of allergic contact dermatitis from propolis was published in 1915 and described a beekeeper with contact dermatitis on his fingers and wrist. (medscape.com)
  • It may have a calming effect on the immune system and reduce allergic responses. (biolyphar.com)
  • Furthermore, while many people find it beneficial, some individuals may be allergic to propolis or experience side effects. (biolyphar.com)
  • While propolis is generally considered safe for most people, there can be adverse effects or allergic reactions in some individuals. (biolyphar.com)
  • Some people may be allergic to propolis. (biolyphar.com)
  • Our findings shouldlencourage health practitioners to apply propolis mouth rinse for the oral care of patients under chemotherapy. (nih.gov)
  • Taking propolis by mouth or rinsing the mouth with a propolis mouth rinse helps heal sores caused by cancer drugs. (medlineplus.gov)
  • Both propolis extracts exhibited high anti-HSV-1 activity when the viruses were pretreated with these drugs prior to infection. (nih.gov)
  • Previous work showed that propolis extracts exhibited in vitro activity against Trypanosoma cruzi (Higashi and de Castro, 1994). (propolisscience.org)
  • Propolis is known for its strong antimicrobial properties. (biolyphar.com)
  • The aim of this study is to investigate the antimicrobial properties of six propolis solutions and evaluate their cytotoxicity on gingival fibroblasts at different dilutions. (deu.edu.tr)
  • Propolis extracts might be suitable for topical application against herpes infection. (nih.gov)
  • In group 2, there were 29 patients (ulceration area: 7.2-9.4 cm 2 ) treated by means of Unna boot leg compression without topical propolis treatment. (hindawi.com)
  • Topical application of propolis may cause skin irritation, including redness, itching, or a rash. (biolyphar.com)
  • As a topical treatment, coconut oil is a safe option without many, if any, adverse effects. (medicalnewstoday.com)
  • Propolis is a natural, resinous, hive product with various bioactive properties. (tubitak.gov.tr)
  • Since propolis contains many bioactive substances, its phenolic and flavonoid content was also quantified. (beeandyou.eu)
  • This innovative whole-health formula delivers powerful effects for immune system response, digestive support, and antioxidant systems. (naturalmedicinejournal.com)
  • Propolis may help support the immune system and improve overall health. (biolyphar.com)
  • The antioxidant effects of bioflavonoids may help to maintain a healthy immune system. (uk.com)
  • In order to determine the mode of antiviral action of propolis, the extracts were added at different times during the viral infection cycle. (nih.gov)
  • Additional exclusion criteria were chronic or critical leg ischemia, contraindications to compression therapy, immobilization in orthesis or plastic cast, paresis related to stroke or paraplegia, chronic cardiac failure with peripheral swelling, systemic infection, and previous propolis implementation. (hindawi.com)
  • Here, we further investigated Et-Bra targets in T. cruzi and its effect on experimental infection of mice. (fiocruz.br)
  • These findings suggest that Turkish WEP may have a limited effect on the development of tuberculosis infection in this guinea-pig model. (anadolu.edu.tr)
  • Aloe vera is well-known for its soothing and moisturizing properties, while propolis extract is a natural antiseptic that helps protect the skin from infection. (love.com)
  • Propolis keeps the hive germ-free due to its antibiotic effect. (niche-beauty.com)
  • The long-term effectiveness of most antibiotic treatments is restricted by both pathogen drug resistance and non-target effects on the host's commensal microbial community. (nature.com)
  • Propolis is thought to contain a natural antibiotic, called galangin, and is used in a variety of remedies to treat or prevent low-grade infections, especially in people who do not want to take antibiotics. (healthy.net)
  • In this study, we examined the antitumor effects of GS-002 in human hepatoma Hep3B and HepG2 cells in vitro . (hindawi.com)
  • These results suggest that the induction of apoptosis by the propolis derivative, GS-002, is partially mediated through ER stress and ATF-3-dependent pathways, and GS-002 has the potential for development as an antitumor drug. (hindawi.com)
  • Exercise, propolis consumption and exercise led to a significant reduction in fasting blood glucose, insulin, insulin resistance and glycosylated hemoglobin simultaneously with propolis consumption (P≥0.05). (ac.ir)
  • In addition, exercise with propolis consumption compared to exercise and propolis had a more significant effect on lowering fasting blood glucose, insulin, IR, and glycosylated hemoglobin (P≥0.05). (ac.ir)
  • We evaluated the effect of Brazilian propolis (P1) in guinea pig isolated trachea in vitro contracted with hista-mine, in paw oedema induced by histamine in mice and anti-ulcerogenic effect of propolis formulation in mice. (scirp.org)
  • In the guinea pig trachea Brazilian propolis extract (10 μg/mL) produced a non-significant inhibition in the cumulative response curve for histamine. (scirp.org)
  • Brazilian propolis has recently been tested in the guinea pig isolated trachea, in vitro, and shows a potent relaxant effect. (scirp.org)
  • Although propolis sensitization was originally thought to be most commonly related to occupational exposure, most cases today result from use of propolis-containing products either applied topically (as with cosmetics) or ingested orally. (medscape.com)
  • However, the extracts containing many different components exhibited significantly higher antiherpetic effects as well as higher selectivity indices than single isolated constituents. (nih.gov)
  • As with any natural remedy, it's advisable to consult with a healthcare professional before using propolis for medicinal purposes, especially if you have allergies or are taking medications. (biolyphar.com)
  • Propolis has been a popular remedy in places like Brazil for many years, but has not been widely adopted by people in the US yet. (bee-pollen-buzz.com)
  • As a natural remedy it will be incredibly useful for at least it's anti-viral effects. (infiniteunknown.net)
  • Bee propolis was evaluated as a potential remedy to reduce the number of mouth ulcer outbreaks. (infiniteunknown.net)
  • Recent studies have shown that there may be a place for trying propolis on skin cancer but these were test tube studies and not done on humans so trying this as a remedy for skin cancer should be done with the co-operation of your preferred health practitioner. (infiniteunknown.net)
  • A growing body of evidence indicates that bee products like propolis can significantly reduce the duration of a cold and relieve symptoms. (bee-pollen-buzz.com)
  • If not treated in time, it will significantly affect the physical and psychological health of patients. (bvsalud.org)
  • Propolis, a bee product, can be regarded as one of the potential natural sources in folk medicine, displaying strong antimicrobial activity. (propolisscience.org)
  • Additionally, propolis may ease COVID-19 symptoms and help heal the lungs. (bellyfatlossguru.com)
  • Some people use propolis to alleviate the symptoms of the common cold and respiratory infections. (biolyphar.com)
  • In individuals with asthma, propolis exposure may trigger or exacerbate asthma symptoms. (biolyphar.com)
  • A recent study focused on whether propolis could help cut cold symptoms and duration across the board. (bee-pollen-buzz.com)
  • In a study involving 40 children between he ages of two and 12, participants with cold symptoms were given a propolis nasal spray . (bee-pollen-buzz.com)
  • In the study, those who took propolis had a dramatic improvement in symptoms by day four and were completely symptom-free by the end of the week. (bee-pollen-buzz.com)
  • By incorporating propolis into your routine when cold symptoms start to get to you, you can potentially cut the severity of your symptoms and make them go away faster. (bee-pollen-buzz.com)
  • By adding propolis to your routine early on, you can cut out symptoms sooner and get back to full energy and health. (bee-pollen-buzz.com)
  • There were significant differences in OM, wound and erythema in propolis group compared to placebo, but no significant difference in eating and drink ability. (nih.gov)
  • There were two groups of patients, one group who took a placebo capsule and the other group who took a propolis capsule. (infiniteunknown.net)
  • This applied research was conducted on 60 women with type 2 diabetes, who were selected from Shiraz Medical Center and divided into four groups of 15, including 1) placebo, 2) exercise with placebo, 3) exercise with propolis, and 4) propolis. (ac.ir)
  • All of these claims must be helpful in potentizing the placebo effect, but more research needs to be done before propolis is readily adopted by the scientific community. (healthy.net)
  • In this randomised, controlled study patients undergoing chemotherapy were included consecutively and randomised to an experimental group receiving propolis mouthwash (n = 20) and a control group receiving diluted water (n=20). (nih.gov)
  • This study found that oral care with propolis as mouthwash for patients undergoing chemotherapy is an effective intervention to improve oral health. (nih.gov)