• Calcinosis cutis is condition in which there are irregular nodular deposits of calcium salts in skin and subcutaneous tissue. (wikipedia.org)
  • Calcinosis is dystrophic calcification of the soft tissue which can lead to painful and debilitating disease. (stanfordhealthcare.org)
  • Using laboratory test results (serum calcium and phosphate levels) and clinical history, calcinosis circumscripta can be further categorized into four subtypes: dystrophic, iatrogenic, metastatic, and idiopathic calcification. (tmu.edu.tw)
  • In secondary scrotal calcinosis, the causes are identified as calcification of epidermal cysts, calcific degeneration of the dartos muscle, and dystrophic calcification of subcutaneous soft tissue secondary to chronic inflammation or infection. (patientcareonline.com)
  • They examined 14 cases and concluded that scrotal calcinosis results from calcification of hair follicles and epidermal cysts. (patientcareonline.com)
  • Shah V, Shet T. Scrotal calcinosis results from calcification of cysts derived from hair follicles: a series of 20 cases evaluating the spectrum of changes resulting in scrotal calcinosis. (patientcareonline.com)
  • Tumoural calcinosis (TC) is a rare disorder characterized by nonneoplastic amorphous calcium deposition that tends to occur in soft tissues around the large joint. (biomedcentral.com)
  • Dystrophic calcification can occur even if the amount of calcium in the blood is not elevated, in contrast to metastatic calcification, which is a consequence of a systemic mineral imbalance, including hypercalcemia and/or hyperphosphatemia, that leads to calcium deposition in healthy tissues. (wikipedia.org)
  • citation needed] These calcifications are an indication of previous microscopic cell injury, occurring in areas of cell necrosis when activated phosphatases bind calcium ions to phospholipids in the membrane. (wikipedia.org)
  • Caseous necrosis in T.B. is most common site of dystrophic calcification. (wikipedia.org)
  • There is cell-mediated injury targeted at striated muscle with resultant atrophy, edema, coagulation necrosis, fibrosis and calcification. (pacs.de)
  • When lymphoma is suspected, tissue should be set aside for flow cytometry, but necrosis and fibrosis often limit the evaluation. (basicmedicalkey.com)
  • Pulpal complications of caries, extensive wear or other external irritation may result in symptomatic or asymptomatic inflammation, followed by partial or progressive pulp tissue degradation and necrosis. (tannlegetidende.no)
  • The latter is a chronic eosinophilic inflammatory disorder involving subcutaneous tissues, lymph nodes of head and neck or parotid gland and it is characterized by lymphadenopathy, peripheral eosinophilia and elevated IgE. (ispub.com)
  • Dystrophic calcification suggestive of chronic congenital ischemic change due to venous malformation was also noted. (pediatricneurosciences.com)
  • Yellow nail syndrome is a rare disorder causing chronic exudative pleural effusions, lymphedema, and dystrophic yellow nails-all thought to be the result of impaired lymphatic drainage. (msdmanuals.com)
  • Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. (wikipedia.org)
  • Osseous metaplasia is usually caused by osteoblasts differentiating from fibroblasts secondary to inflammation, tissue damage, exposure to substances such as bone morphogenetic proteins released from neoplastic cells, or dystrophic calcification in necrotic tissue. (jkaoms.org)
  • Delayed image from a technetium-99m (99mTc) methylene diphosphonate bone scan (performed at the time of the first radiograph) demonstrates marked soft-tissue uptake of tracer. (medscape.com)
  • A 54-year-old woman was referred to the University Hospitals Leuven with the preliminary diagnosis of a soft tissue tumor in the right upper leg identified as a mass of 43 mm × 62 mm on plain radiograph and echography. (sicot-j.org)
  • To examine the role of OPN in vascular calcification, OPN mutant mice were crossed with matrix Gla protein (MGP) mutant mice. (silverchair.com)
  • Importantly, mice deficient in both MGP and OPN had twice as much arterial calcification as MGP −/− OPN +/+ at 2 wk, and over 3 times as much at 4 wk, suggesting an inhibitory effect of OPN in vascular calcification. (silverchair.com)
  • Cysts can show calcification. (wikipedia.org)
  • Examination of a biopsy specimen stained with hematoxylin and eosin (H & E) revealed several dilated epidermal cysts ( B ). These cysts exhibited calcification of their keratin contents, with little evidence of active inflammation. (patientcareonline.com)
  • Conventionally lipomas are composed of mature adipose tissue, but sometimes they can contain other mesenchymal elements such as fibrous tissue, blood vessels, and, less frequently, cartilage or bone. (sicot-j.org)
  • There is no normal brain tissue between abnormal blood vessels in the compact or glomerular type. (springeropen.com)
  • 16 Although the majority of osteochondromas are incidental, uncommon complications include fracture, malignant transformation, and compression of adjacent soft tissue structures such as blood vessels and nerves (Figure 4). (appliedradiology.com)
  • Connective tissue provides strength and flexibility to structures such as bones, ligaments, muscles, and blood vessels. (nih.gov)
  • Axial T2 MRI through the hips (above) shows small patchy areas of increased T2 signal bilaterally and symmetrically in the gluteus muscles and in the subcutaneous tissues of the lateral and posterior thighs which show mild enhancement on axial T1 MRI with contrast (below).The diagnosis was mild dermatomyositis. (pacs.de)
  • Rarely, biopsy is required to establish preoperative tissue diagnosis. (medscape.com)
  • Since the direct diagnosis of AVM in non-contrast brain-computed tomography (CT) is difficult, the detection of calcification in these regions requires the presence of AVM in the differential diagnosis. (springeropen.com)
  • This longitudinal Doppler image shows perfused testicular tissue exuding through disrupted tunica albuginea, eliminating any doubt regarding the diagnosis of testicular rupture. (medscape.com)
  • The tumor cells were focally embedded in a myxochondroid and osteoid-like matrix (Figures 8 and 9 ) with scattered areas of dystrophic calcification (Figure 8 ). (upmc.edu)
  • The tumor is a well-delineated but unencapsulated mass of densely collagenized, hypocellular fibrous tissue with a storiform pattern and prominent clefts between collagen bundles. (medscape.com)
  • This tumor-like disease is increasingly found throughout the tropics and is commonly associated with high human population density, yet little is known about the etiology, pathology, or calcification behavior of the disease. (nist.gov)
  • The term odontoma was first coined by Broca in 1866, who defined it as a tumor formed by overgrowth of complete dental tissue 2 . (bvsalud.org)
  • eroded, and the tumor grows with broad pushing fronts into the surrounding soft tissue. (pdfslide.net)
  • Lighter flecks of calcification or necrotic tumor usually are evident grossly in the tumor. (entokey.com)
  • Odontomas have also been classified as central odontoma (which occur inside the bone), peripheral odontoma (which occur in the soft tissue covering the tooth-bearing portions of the jaws which has the tendency to exfoliate), and erupted odontoma 4 . (bvsalud.org)
  • Contrast enhanced computed tomography (CECT) of the abdomen revealed 13 X 13 X 11 cm lobulated mixed (predominantly solid) markedly enhancing soft tissue mass is noted in the right adnexal region with enhancing intralesional and perilesional vessels with peripheral irregular dense calcification suggestive of yolk sac tumour (Figure 1a). (ommegaonline.org)
  • CECT abdomen showing mixed, markedly enhancing soft tissue mass arising in the right adnexal region with enhancing intralesional and perilesional vessels with peripheral irregular dense calcification suggestive of yolk sac tumour. (ommegaonline.org)
  • The inherited disorder pseudoxanthoma elasticum may lead to angioid streaks with calcification of Bruch's membrane, the elastic tissue below the retinal ring. (wikipedia.org)
  • however, the term has fallen into disfavor because primary muscle inflammation is not a necessary precursor for such ossification and the ossification does not always occur in muscle tissue (frequently showing a predilection instead for fascia, tendons, and other mesenchymal soft tissues). (medscape.com)
  • Intracranial calcifications may occur physiologically or pathologically for many reasons. (springeropen.com)
  • Although it is generally regarded as being very safe, potentially severe complications can occur when it comes into contact with soft tissue. (restorativedentistry.org)
  • Dense scars may undergo hyaline degeneration and calcification. (wikipedia.org)
  • One can distinguish superficial (subcutaneous) and deep lipomas (muscular tissue) depending on their localization. (sicot-j.org)
  • An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcification, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease. (lookformedical.com)
  • T2 sequences revealed diffuse dystrophic calcification deep in the mass ( Figure 2 ). (sicot-j.org)
  • Proliferative or diffuse type is rare and is characterized by the interspersed of normal brain tissue between abnormal vessels. (springeropen.com)
  • Diffuse calcifications were also observed in bilateral basal ganglia and both hemispheres, more on the left. (springeropen.com)
  • Computed tomography (CT) scans demonstrate a hyperdense soft-tissue mass in the joint or tendon sheath. (medscape.com)
  • On computed tomography, there was a round hard-tissue mass approximately 2 cm in diameter on the right palate area. (jkaoms.org)
  • On the whole, MRI is superior to computed tomography (CT scan) excluding the fact that dystrophic calcification cannot be visualized on MRI( 6 ). (ispub.com)
  • The gross specimen consisted of multiple fragments of soft tissue and attached bone. (upmc.edu)
  • Heterotopic ossification (HO) is the abnormal formation of true bone within extraskeletal soft tissues. (medscape.com)
  • Osseous metaplasia is defined as the formation of lamellar bone inside soft tissue structures where bone normally does not exist. (jkaoms.org)
  • It results from the transformation of non-osseous connective tissue into mature bone. (jkaoms.org)
  • At the time of referral, plain radiographs of the hip and pelvis showed crumbly calcification within a soft tissue mass posterior to the trochanteric region without a sign of bone erosion. (sicot-j.org)
  • Adjoining soft tissues very poorly absorb the X-ray beam and make an natural backdrop for bone structure. (doclecture.net)
  • 6. To learn a volume and structure of soft tissues around of bone. (doclecture.net)
  • 8. The soft tissues which surround a bone (joint). (doclecture.net)
  • Osteoporosis (see fig 11.7) is a dystrophic process in a bone on account of disturbance: nervous regulation, blood circulation, decrease of osteoblastic activity and other. (doclecture.net)
  • A bone loses mineral and organic components, bone tissue is replaced by extended vessels, marrow, osteoid tissue, that is by tissue, characteristic to the normal bone. (doclecture.net)
  • Calcification or bone was noted in one third (seven of 20) of the adrenal tumours. (bmj.com)
  • When the adaptive potential of the cells is exceeded or inexistent, cells and tissues will be damaged, producing cell injury and in the end, cell death . (pathologyatlas.ro)
  • Therefore, we propose that damage to and subsequent release of mtDNA elicits a protective signalling response that enhances nDNA repair in cells and tissues, suggesting that mtDNA is a genotoxic stress sentinel. (regenerativemedicine.net)
  • Fibrous growths of the oral soft tissues are fairly common and include a diverse group of reactive and neoplastic conditions. (medscape.com)
  • Later came to be used to describe all forms of lymphoid neoplastic proliferations that arise as discrete tissue masses. (fdocuments.net)
  • Histologically, a fibroma is an unencapsulated, solid, nodular mass of dense and sometimes hyalinized fibrous connective tissue that is often arranged in haphazard fascicles. (medscape.com)
  • See the image below depicting fibrous tumorlike growth of the oral soft tissues. (medscape.com)
  • This noninflamed cyst shows a thin, nonkeratinized epithelial lining and a loosely arranged fibrous connective tissue wall. (easynotecards.com)
  • Rarely, foci of dystrophic calcification may be seen in an area of PVNS. (medscape.com)
  • Differentiating calcifications from hemosiderin-laden foci in the setting of PVNS may be difficult, and plain films should be used in this setting to confirm or deny the presence of calcifications. (medscape.com)
  • Sturge-Weber syndrome is a mesodermal phakomatosis characterized by port-wine naevus covering face and cranium supplied by first division of trigeminal nerve along with atrophy and calcification of cerebral hemisphere homolateral to the skin lesion. (pediatricneurosciences.com)
  • In arteriovenous malformations (AVMs), calcification is not uncommon and is usually detected in the lesion vessel walls and surrounding parenchyma. (springeropen.com)
  • However, rarely calcifications can also be seen in bilateral basal ganglia and especially in watershed areas, which are far from the lesion. (springeropen.com)
  • Bilateral basal ganglion calcification and subcortical calcifications far from the lesion have rarely been reported. (springeropen.com)
  • On T1-weighted images, increased signals in the subcortical areas at the lesion side and in bilateral putamen and thalamus were evaluated in favor of calcification. (springeropen.com)
  • The term lesion defines the totality of the morphological and functional changes that appear in cells, tissues and organs as a response to an aggression (excessive physiological stress and pathological stimuli). (pathologyatlas.ro)
  • They are composed of enamel, dentin, cementum and occasionally pulp tissue 10 . (bvsalud.org)
  • Whereas dentin forms the main body of the tooth, providing support to enamel, resilience under occlusal loads, and physical protection of the pulp against microbes and other noxious substances, the pulp tissue readily reacts to the external irritation, initiating and orchestrating the defensive reactions that aim to keep the tooth functional and protect it from microbial invasion. (tannlegetidende.no)
  • Tertiary dentin increases the mineralized barrier thickness between external irritation and pulp tissue, aiming to retain the pulp tissue vital and non-infected. (tannlegetidende.no)
  • Reactionary dentin is tubular and relatively similar to secondary dentin in structure, while reparative dentin (also called fibrodentin or even "calcified scar tissue" [ 4 ] is believed to be relatively impermeable, forming a barrier between tubular dentin and pulp tissue. (tannlegetidende.no)
  • abstract = "Soft-tissue calcification refers to a broad category of lesions. (tmu.edu.tw)
  • A comprehensive suite of trace elements and boron isotopes (δ11B) were measured in skeletal GAs to assess calcification behavior and uptake of essential and toxic metals. (nist.gov)
  • Tumours with adipose tissue as the sole or one of the major components were selected for review. (bmj.com)
  • In dystrophic calcification, basophilic calcium salt deposits aggregate, first in the mitochondria, then progressively throughout the cell. (wikipedia.org)
  • In aggregate, our findings show that dystrophic calcification processes could explain structural differences seen in GA vs unaffected skeletons and highlight the use of approaches herein to shed light on disease pathophysiology in corals. (nist.gov)
  • 9,10,12 Although signs of periosteal osteosarcoma may appear subtle on knee radiographs, magnetic resonance imaging (MRI) typically reveals a large, extraosseous soft-tissue mass with intramedullary invasion in some cases. (appliedradiology.com)
  • Plain radiographic findings of the knee apparently are normal except for the curvilinear calcification seen peripherally to the medial femoral condyle. (medscape.com)
  • PATIENTS: Nineteen children with cutaneous findings in the first 4 weeks of life and subsequently diagnosed with LCH based on compatible tissue histologic analysis, confirmed by electron microscopy and/or immunohistochemical analysis. (thedoctorsdoctor.com)
  • The image of bones, joints and soft tissues in an axial projection is the feature of computer tomograms. (doclecture.net)
  • Dystrophic calcification is seen most commonly in which of the following oral tissues? (dentaldevotee.com)
  • Notre technologie de pointe modulaire s'appuie sur l'expérience de milliers de mises en place d'Aperio Digital Pathology à travers le monde. (leicabiosystems.com)
  • Plain radiographs demonstrate signs similar to joint effusion or soft-tissue swelling. (medscape.com)
  • plain radiographs and ecchography of the right hip revealing a soft tissue mass with scattered calcifications. (sicot-j.org)
  • This pictorial essay presents a systematic approach to the imaging features of soft-tissue calcifications and related diseases. (tmu.edu.tw)
  • G71.2) The congenital myopathies do not show evidence for either a progressive dystrophic process (i.e., muscle death) or inflammation, but instead characteristic microscopic changes are seen in association with reduced contractile ability of the muscles. (wikidoc.org)
  • Senile degenerative changes may be accompanied by calcification. (wikipedia.org)
  • Other characteristic features include widely spaced eyes (hypertelorism), eyes that do not point in the same direction (strabismus), a split in the soft flap of tissue that hangs from the back of the mouth (bifid uvula), and an opening in the roof of the mouth (cleft palate). (nih.gov)
  • Even though dentin is mineralized and the pulp a loose connective tissue, they form a developmentally interdependent and functionally integrated continuum, often referred to as the dentin‐pulp complex, where physiologic and pathologic reactions in one will also affect the other. (tannlegetidende.no)
  • Dentin is mineralized collagenous tissue, a nanocrystalline-reinforced collagen biocomposite, with 70 w-% (55 vol-%) biological hydroxyapatite (Ca10(PO4)6(OH)2) and 20 w-% (30 vol-%) organic components [ 1 ]. (tannlegetidende.no)
  • medullary cavity, growing through the cortex, and forming a relatively well-circumscribed soft tissue mass. (pdfslide.net)
  • In this article, we present a 47-year-old case of hemispheric AVM accompanied by bilateral basal ganglia calcification. (springeropen.com)
  • Atheroma in aorta and coronaries frequently undergo calcification. (wikipedia.org)
  • Calcifications are frequently identified by radiologists in daily practice. (tmu.edu.tw)