Cimetidine treats acid reflux, stomach ulcers, heartburn, and other digestion problems caused by too much stomach acid. (rxwiki.com)
Cimetidine is also used to prevent ulcers in certain circumstances and to treat certain conditions that are associated with over secretion of acid by the stomach (i.e. (medbroadcast.com)
When treating duodenal or gastric ulcers, the dose ranges from 800 mg to 1,200 mg daily, in divided doses. (medbroadcast.com)
The recommended dose of cimetidine to treat ulcers caused by anti-inflammatory medications is 800 mg daily, either as 400 mg taken twice a day or 800 mg taken at bedtime. (medbroadcast.com)
These drugs are used to treat gastric and duodenal ulcers by inhibition of gastric acid secretion stimulated by food, insulin, histamine, caffeine, and pentagastrin. (fsu.edu)
4 Two years later, he published a report on the use of licorice juice in the treatment of duodenal ulcers. (naturalmedicinejournal.com)
Duodenal ulcers are found at the beginning of the small intestine known as the duodenum. (dosingpdf.com)
A person may have both gastric and duodenal ulcers at the same time. (dosingpdf.com)
Thus, amoxicillin cures a strep throat, and cimetidine promotes the healing of duodenal ulcers. (nursingipd.com)
Carafate is a branded medication for duodenal ulcers that may occur due to gastritis. (medicalnewstoday.com)
According to the National Library of Medicine (NLM) , the Food and Drug Administration (FDA) also approves sucralfate for treating duodenal ulcers for up to 8 weeks. (medicalnewstoday.com)
Duodenal ulcers may occur as a result of someone having gastritis. (medicalnewstoday.com)
The term peptic ulcer refers to ulcers that occur in the stomach (gastric ulcer) or the first portion of the small intestine (duodenal ulcer). (iherb.com)
Duodenal ulcers are more common with an estimated frequency rate of 6 to 12% of the adult population in the United States. (iherb.com)
Duodenal ulcers are 4 times more common in men than in women and 4 to 5 times more common than gastric ulcers. (iherb.com)
Even though duodenal and gastric ulcers occur at different locations, they appear to be the result of similar mechanisms. (iherb.com)
In the past, the focus has primarily been on the acidic secretions of the stomach as the primary cause of both gastric and duodenal ulcers. (iherb.com)
As a group, patients with duodenal ulcers have twice as many parietal cells in their stomach compared to people without ulcers. (iherb.com)
For uncomplicated duodenal ulcers, omeprazole 20 mg once a day or lansoprazole 30 mg once a day is given for 4 weeks. (msdmanuals.com)
Omeprazole is used for up to 4 weeks to treat and relieve the symptoms of active duodenal ulcers. (medscape.com)
Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. (nih.gov)
Two double-blind randomized placebo-controlled U.S. multicenter trials have demonstrated that sucralfate (1 g bid) is effective as maintenance therapy following healing of duodenal ulcers. (nih.gov)
Bismuth, metronidazole, and tetracycline is used along with other ulcer medications to treat duodenal ulcers. (medlineplus.gov)
It is used to treat stomach and duodenal (intestinal) ulcers, gastroesophageal reflux disease (GERD), and conditions where too much stomach acid is secreted, such as Zollinger-Ellison syndrome. (medbroadcast.com)
It is also used to prevent duodenal ulcers and prevent GERD symptoms from coming back. (medbroadcast.com)
Duodenal ulcers are almost always benign, but a gastric ulcer may be malignant. (rawfoodexplained.com)
Cimetidine belongs to a group of drugs called Histamine H2 Receptor Antagonists. (rxwiki.com)
Cimetidine is a competitive inhibitor of histamine at the histamine H2 receptors of the parietal cells, and thus is known as a histamine antagonist. (fsu.edu)
Cimetidine inhibits histamine at H2 receptors of the gastric parietal cells, which results in reduced gastric acid secretion, gastric volume, and hydrogen concentrations. (medscape.com)
Acid secretion5
With Sir Godfrey Milton-Thompson, Roy Pounder and George Misiewicz he evaluated the first H2-receptor antagonists to be given to man, refining new techniques to assess acid secretion, and demonstrating efficacy in duodenal ulcer disease, a common cause of significant morbidity in sailors. (wikipedia.org)
This study investigated whether an antireflux agent would remain effective after the decrease in acid secretion produced by a typical clinical dosage regimen of cimetidine (400 mg q.d.s., 7 days). (strath.ac.uk)
Manomet 800 mg orally at bedtime reduces mean hourly H + activity by greater than 85% over an eight-hour period in duodenal ulcer patients, with no effect on daytime acid secretion. (sdrugs.com)
The effect of a 300 mg breakfast dose of Manomet continued for at least four hours and there was partial suppression of the rise in gastric acid secretion following the luncheon meal in duodenal ulcer patients. (sdrugs.com)
Gastric Ulcer Duodenal Ulcer Acid secretion Connection with NSAID use H. pylori as etiology Age incidence MortalitySymptomsRelief measures Complications Advantage Disadvantage Maalox 30 mL after meals and at bedtime Cimetidine 200 mg 4 times a day Sucralfate 1 gram four times a day 30 minutes before meals and at bedtime. (slideshare.net)
Omeprazole2
1999. Use of omeprazole in the management of giant duodenal ulcer: Results of a prospective study. (uc.edu)
A 2020 review suggests doctors may favor proton pump inhibitors (PPIs) , such as omeprazole and cimetidine, for gastritis. (medicalnewstoday.com)
Ulcer patients2
Manomet 1600 mg orally at bedtime produces 100% inhibition of mean hourly H + activity over an eight-hour period in duodenal ulcer patients, but also reduces H + activity by 35% for an additional five hours into the following morning. (sdrugs.com)
Cimetidine pre-treatment slightly, but not significantly, increased the time for half the meal and the Gaviscon to empty from the stomach. (strath.ac.uk)
For more information about the relevant anatomy, see Stomach Anatomy and Duodenal Anatomy. (medscape.com)
Specifically, the development of a duodenal or gastric ulcer is a result of some factor damaging the protective factors which line the stomach and duodenum. (iherb.com)
Виразкова хвороба A peptic ulcer is an erosion in a segment of the gastrointestinal mucosa, typically in the stomach (gastric ulcer) or the first few centimeters of the duodenum (duodenal ulcer), that penetrates. (msdmanuals.com)
Blockers1
In addition, cimetidine and, to a lesser extent, the other H2 blockers may interfere with the body's elimination of certain medications, such as theophylline for asthma, warfarin for excessive blood clotting, and phenytoin for seizures. (merckmanuals.com)
Sucralfate4
AdvantageDisadvantageMaalox 30 mL after meals and at bedtime Cimetidine 200 mg 4 times a day Sucralfate 1 gram four times a day 30 minutes before meals and at bedtime History: A 55 year-old man is hospitalized with GI bleeding. (slideshare.net)
CARAFATE (sucralfate) Oral Suspension is indicated in the short-term (up to 8 weeks) treatment of active duodenal ulcer. (nih.gov)
While short-term treatment with sucralfate can result in complete healing of the ulcer, a successful course of treatment with sucralfate should not be expected to alter the post healing frequency or severity of duodenal ulceration. (nih.gov)
Results from Clinical Trials Healing Rates for Acute Duodenal Ulcer Treatment nWeek Healing RatesWeek Healing RatesWeek Healing RatesSucralfate Oral Suspension 14523 (16%) 66 (46%) 95 (66%) Placebo 14710 (7%)39 (27%)58 (39%)P=0.016 +P=0.001 P=0.0001 Equivalence of Sucralfate Oral Suspension to sucralfate tablets has not been demonstrated. (drugcentral.org)
Patients7
A double-blind, double-dummy trial to compare carbenoxolone (Duogastrone) with cimetidine has been carried out in patients with duodenal ulcer. (ox.ac.uk)
Sixty patients completed the six week trial period, 31 patients were treated with carbenoxolone and 29 with cimetidine. (ox.ac.uk)
Endoscopy after six weeks of therapy showed healing in 61% of patients receiving carbenoxolone and 72% in those receiving cimetidine, a difference which is not significant. (ox.ac.uk)
Cimetidine is also helpful in treating upper gastrointestinal bleeding in critically ill patients. (fsu.edu)
Doxepin hydrochloride was given to 12 patients with duodenal ulcer and one patient with an anastomotic ulcer. (jamanetwork.com)
Eight patients, including the four receiving hemodialysis, had not responded to treatment after eight weeks of cimetidine and/or antacid therapy. (jamanetwork.com)
Someone with gastritis may go on to develop a duodenal ulcer, which is an ulcer on the first part of a person's small intestine. (medicalnewstoday.com)
Carbenoxolone (duogastrone) and cimetidine in the treatment of duodenal ulcer--a therapeutic trial. (ox.ac.uk)
1992. A Multicenter, double-blind, randomized, placebo-controlled, comparison of nocturnal Roxatidine in the treatment of active duodenal ulcer disease. (uc.edu)
The area under the gastric and fundal emptying curves demonstrated that Liquid Gaviscon (sodium alginate compound) had a significantly greater gastric residence than the meal, both during the control period and after cimetidine pre-treatment, and that the majority of the Gaviscon was located in the fundus. (strath.ac.uk)
The distribution of Gaviscon into the fundus was not affected by cimetidine pre-treatment. (strath.ac.uk)
Duodenal ulcer is a chronic, recurrent disease. (nih.gov)
Bedtime1
If the anti-inflammatory is not stopped, the cimetidine may be continued as 400 mg at bedtime. (medbroadcast.com)
Medication2
Cimetidine is both an over-the-counter and a prescription medication. (rxwiki.com)
Do not take this medication if you are allergic to cimetidine or any ingredients of the medication. (medbroadcast.com)
Occur1
A single ulcer is most common, but two and occasionally more (duodenal, gastric, or both) do occur. (rawfoodexplained.com)
Precautions1
See the "Cimetidine Precautions" section. (rxwiki.com)
Symptoms1
Do not give Cimetidine to anyone else, even if they have the same symptoms as you do. (pocketpills.com)
Prescription1
You could get Cimetidine delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. (pocketpills.com)
Weeks1
For a duodenal ulcer, doctors may prescribe 1 gram (g) four times per day for 8 weeks, followed by 1 g twice daily for maintenance therapy. (medicalnewstoday.com)