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  • acinar
  • There was no accompanying conventional acinar adenocarcinoma and TTF‐1 was distinctly positive in the nuclei of the malignant cells. (pubmedcentralcanada.ca)
  • When a thorough systemic investigation disclosed no evidence of other primary tumours, a radical prostatectomy was performed which revealed predominant ductal adenocarcinoma with a minor component of acinar adenoarcinoma. (pubmedcentralcanada.ca)
  • Modelling of different genetic events in mice suggests both ductal and acinar cells can give rise to PDAC. (bmj.com)
  • Design We examined the contribution of cellular origin to PDAC development by inducing PDAC-associated mutations, Kras G12D expression and Trp53 loss, specifically in ductal cells ( Sox9CreER;Kras LSL-G12D ;Trp53 flox/flox (' Duct:KP cKO ')) or acinar cells ( Ptf1a CreER ;Kras LSL-G12D ;Trp53 flox/flox (' Acinar:KP cKO ')) in mice. (bmj.com)
  • Acinar-cell-derived tumours also had a higher prevalence of mucinous glandular features reminiscent of early mPanIN lesions. (bmj.com)
  • glands
  • This requires the involvement of periurethral glands: Glandular component morpho- logically benign adenosquamous cell carcinoma grossly conned to the patient is incapable of consenting, agreement of the ipsilateral forearm hyperextend the elbow in a secure perimeter. (meownowfl.org)
  • Adenocarcinomas can arise in many tissues of the body owing to the ubiquitous nature of glands within the body, and, more fundamentally, to the potency of epithelial cells. (wikipedia.org)
  • Lesions
  • Lesions that meet the criteria for adenocarcinoma in situ have formerly been classified as BAC according to the strict definition of the 1999 (2) and 2004 (3) WHO classifications and as type A and B adenocarcinoma according to the 1995 Noguchi classification. (thefreedictionary.com)
  • cells
  • To be classified as adenocarcinoma, the cells do not necessarily need to be part of a gland, as long as they have secretory properties. (wikipedia.org)
  • An example of a normal hyperplastic response would be the growth and multiplication of milk-secreting glandular cells in the breast as a response to pregnancy, thus preparing for future breast feeding. (wikipedia.org)
  • pure
  • For small ([less than or equal to] 3 cm), solitary adenocarcinomas with pure lepidic growth, we recommend the term adenocarcinoma in situ , which defines patients who should have 100% disease-specific survival if the lesion is completely resected (strong recommendation, moderate-quality evidence). (thefreedictionary.com)