FirefliesLuciferasesGenes, ReporterFrameshifting, RibosomalPromoter Regions, GeneticMicroRNAsBase SequenceCell LineTransfectionCell Line, TumorRNA, MessengerReverse Transcriptase Polymerase Chain ReactionLuciferases, FireflyFirefly LuciferinLuminescent MeasurementsBeetlesLuciferases, RenillaLuminescenceRenillaLuciferases, BacterialMolecular Sequence DataTranscription, GeneticLuminescent AgentsGene Expression Regulation3' Untranslated RegionsTranscription FactorsResponse ElementsPlasmidsGene ExpressionBinding SitesPhotobacteriumGenetic VectorsCells, CulturedDNA-Binding ProteinsRecombinant Fusion ProteinsElectrophoretic Mobility Shift AssayProtein BindingVibrioCopepodaSignal Transduction5' Flanking RegionGene Expression Regulation, EnzymologicSp1 Transcription FactorGene Transfer TechniquesTumor Cells, CulturedCloning, Molecular5' Untranslated RegionsNF-kappa BBlotting, WesternHeLa CellsHEK293 CellsMutationAmino Acid SequenceDNA PrimersTransgenesNuclear ProteinsDNADown-RegulationGene Expression Regulation, NeoplasticRNA, Small Interfering