• Demoxytocin (INN) (brand names Sandopart, Odeax, Sandopral), also known as desaminooxytocin or deaminooxytocin, as well as 1-(3-mercaptopropanoic acid)oxytocin ([Mpa1]OT), is an oxytocic peptide drug that is used to induce labor, promote lactation, and to prevent and treat puerperal (postpartum) mastitis (breast inflammation). (wikipedia.org)
  • Labour was induced or stimulated after random allocation of the mothers to one of three oxytocics (prostaglandin E2 orally, oxytocin intravenously, or demoxytocin buccally).Using as models, the neurohypophyseal nonapeptide hormone oxytocin and its analogue deaminooxytocin, several directed routes to formation of sulfur-sulfur bridges have been developed and evaluated. (wikipedia.org)
  • Apart from prostaglandin, the other drugs which stimulate uterine contractions are oxytocin and ergometrine. (biologydiscussion.com)
  • Estrogens sensitise the uterus to the action of oxytocin and release of prostaglandin may be a contributing factor to its oxytocic action. (biologydiscussion.com)
  • Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (lookformedical.com)
  • Oxytocin and carbetocin ameliorating effects on restraint stress-induced short- and long-term behavioral changes in rats. (nel.edu)
  • Klenerova V, Krejci I, Sida P, Hlinak Z, Hynie S. Oxytocin and carbetocin ameliorating effects on restraint stress-induced short- and long-term behavioral changes in rats. (nel.edu)
  • while other drugs, such as oxytocin (PitocinĀ®) accelerate the labor. (vaccinationinformationnetwork.com)
  • Has the government picked up the funding of lifesaving drugs such as oxytocin and commodities such as balloon tamponades or anti-shock garments to prevent and or treat postpartum hemorrhage and eclampsia? (ghspjournal.org)
  • Conclusions: Ergometrine plus oxytocin, carbetocin and misoprostol plus oxytocin are more effective uterotonic drug strategies for preventing PPH than the current standard, oxytocin. (searchandrestore.com)
  • Oxytocin is the most widely used uterotonic drug. (searchandrestore.com)
  • Using our NMR facilities, researchers have successfully characterised a number of novel peptides and venoms, including an oxytocic plant peptide that modulates the human oxytocin/vasopressin receptor, and venoms from cone snails, snakes and scorpions. (edu.au)
  • Carboprost tromethamine injection sterile solution (carboprost tromethamine), like other potent oxytocic agents, should be used only with strict adherence to recommended dosages.Carboprost tromethamine injection should be used by medically trained personnel in hospital which can provide immediate intensive care and acute surgical facilities. (drugcentral.org)
  • Carboprost tromethamine should be used only with strict adherence to recommended dosages like other potent oxytocic agents. (rxwiki.com)
  • concomitant use of intravenous oxytocic agents is contraindicated ( 4 , 7.1 ). (drugs.com)
  • In this article we will discuss about the drugs that stimulate uterine contractions. (biologydiscussion.com)
  • Carboprost tromethamine administered intramuscularly stimulates in the gravid uterus myometrial contractions similar to labor contractions at the end of full term pregnancy. (drugcentral.org)
  • The drugs used can cause very strong contractions, necessitating strong pain relief such as epidurals (which has risks for mother and baby). (vaccinationinformationnetwork.com)
  • OXYTOCIC: Capable of producing uterine contractions --------------------------------------------------------------------- PECTORAL: Relieves affections of the chest and lungs. (works.org)
  • In fact, this supplement is used as a medicine to induce labor contractions due to its oxytocic activity. (botanical-online.com)
  • Uterine stimulants (uterotonics or oxytocics) are medications given to cause a woman's uterus to contract, or to increase the frequency and intensity of the contractions. (searchandrestore.com)
  • Prostaglandins, including CERVIDIL, may augment the activity of oxytocic agents and their concomitant use is not recommended. (cervidil.com)
  • The most frequent adverse reactions observed are related to its contractile effect on smooth muscle.In patients studied, approximately two-thirds experienced vomiting and diarrhea, approximately one-third had nausea, one-eighth had temperature increase greater than F, and one-fourteenth experienced flushing.The pretreatment or concurrent administration of antiemetic and antidiarrheal drugs decreases considerably the very high incidence of gastrointestinal effects common with all prostaglandins used for abortion. (drugcentral.org)
  • It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. (curehunter.com)
  • Carboprost belongs to a group of drugs called prostaglandins. (rxwiki.com)
  • The three uterotonic drugs used most frequently are the oxytocins, prostaglandins, and ergot alkaloids. (searchandrestore.com)
  • 1 Prostaglandins and oxytocics. (fistofawesome.com)
  • An induced birth will involve more drugs and procedures and a higher chance of cesarean, especially for first-time mothers. (vaccinationinformationnetwork.com)
  • Have signal functions-such as newborn resuscitation, administration of anticonvulsants and oxytocics, cesarean section, and manual removal of placenta for EmONC and CEmONC-been institutionalized? (ghspjournal.org)
  • Due to system maintenance, the drug interactions feature you are attempting to access is temporarily unavailable. (medscape.com)
  • Psychopharmacology, as the term is used here, refers to the study of the interactions of drugs with the central nervous system (CNS), including physical, behavioral, and subjective effects. (druglibrary.net)
  • CERVIDIL is a prostaglandin analog indicated for the initiation and/or continuation of cervical ripening in pregnant women at or near term in whom there is a medical or obstetrical indication for the induction of labor. (drugs.com)
  • The average peak concentrations of drug were slightly higher following each successive injection of the prostaglandin, but always decreased to levels less than the preceding peak values by two hours after each injection.Five women who had delivery spontaneously at term were treated immediately postpartum with single injection of 250 micrograms of carboprost tromethamine. (drugcentral.org)
  • A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. (lookformedical.com)
  • Although these effects occur most commonly with long term therapy at relatively high doses, they have also been reported with short term or normal doses. (nih.gov)
  • It may be impossible to give a drug in sufficient doses to raise the blood levels enough to have a beneficial effect on the brain. (patentpc.com)
  • They stimulate uterine and bronchial smooth muscle and are often used as oxytocics. (lookformedical.com)
  • The drug is sometimes used off-label (an unapproved use) for acute obstetric uses, including treating preterm labor and treating uterine hyperstimulation. (fistofawesome.com)
  • Drug Therapy During Pregnancy. (wikipedia.org)
  • Sansert is contradicted in pregnancy since it leads to oxytocic actions. (northdrugstore.com)
  • The purpose of this article is to provide an up to date source of information about medication use in pregnancy, to review the US Food and Drug Administration (FDA) pregnancy and lactation categories, and to further describe the recent FDA changes in drug labeling from December 2014. (medscape.com)
  • these drugs do not seem to be associated with clinically significant risks in pregnancy. (medscape.com)
  • The Organization of Teratology Information Specialists is a network of risk-assessment counselors in the United States and Canada who specialize in researching and communicating the risks associated with drug exposures in pregnancy. (medscape.com)
  • All of these are useful resources to learn about drug use in pregnancy. (medscape.com)
  • They are frequently updated and should be referenced frequently, particularly when one is prescribing unfamiliar drugs in pregnancy. (medscape.com)
  • Maternal substance use may consist of any combination of drug, chemical, alcohol, and tobacco use during the pregnancy. (fistofawesome.com)
  • They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. (lookformedical.com)
  • Remove vaginal insert at least 30 minutes before administering an oxytocic agent. (drugs.com)
  • oxytocics and other injections, oral or vaginal herbal preparations, blunt abdominal trauma, and mixtures of battery water (which may contain some sulphuric acid), detergents or household bleach. (safeabortionwomensright.org)
  • Spontaneous prelabour rupture of the membranes (PROM) at term provokes a lively discussion about the risk of vaginal examination (Schutte et al 1983), induction of labour and prophylactic antibiotics. (nzdl.org)
  • Patients with headaches may become nauseated and drug induced distress may be difficult to evaluate. (nih.gov)
  • In some patients, carboprost tromethamine may cause transient bronchoconstriction.Drug plasma concentrations were determined by radioimmunoassay in peripheral blood samples collected by different investigators from 10 patients undergoing abortion. (drugcentral.org)
  • Patients on long-term Sansert therapy may develop retroperitoneal fibrosis, pleuropulmonary fibrosis, and fibrotic thickening of the cardiac valves. (northdrugstore.com)
  • It should not be used in patients anesthetized with agents such as cyclopropane or halothane as these may sensitize the heart to the arrhythmic action of sympathomimetic drugs. (drugs-library.com)
  • Patients suffering from strokes may benefit from an increase in blood flow and increased delivery of anti-stroke or neuroprotective drugs. (patentpc.com)
  • The chapters describe what measurements of drug activity are available in healthy human subjects and in patients, how to make the measurements, their value and their limitations. (taylorfrancis.com)
  • In such patients, care must to be taken to select the safest drug from the necessary class of medication. (medscape.com)
  • In rare cases, promotility agents can be prescribed, though the risks and benefits must carefully be discussed with the patients before the drugs are started. (medscape.com)
  • Epinephrine is used to relieve respiratory distress due to bronchospasm, to provide rapid relief of hypersensitivity reactions to drugs and other allergens, and to prolong the action of anesthetics. (drugs-library.com)
  • Under this condition, ergotamine also has oxytocic and spasmolytic properties. (nih.gov)
  • The active component of Ergot-containing drugs is ergotamine and not lysergic acid diethylamide (LSD). (qualitycoursework.com)
  • Often fluids and drugs are administered intravenously through an IV to help prevent dehydration and control the progression of labor. (vaccinationinformationnetwork.com)
  • A physician caring for a pregnant patient who requires medication should take care in choosing dosages and types of drugs that maximize effectiveness while minimizing fetal risk. (medscape.com)
  • It is essential to understand the effect of medications and to know the point in fetal development when drugs are most toxic and which fetal organs are most susceptible. (medscape.com)
  • Index Nominum 2000: International Drug Directory. (wikipedia.org)
  • According to Dr. Sarah Buckley, writing in the book by Shivam Rachana, (Greenwood Press, Yarra Glen, 2000), "Choosing to forego preventative oxytocics, to clamp late (if at all), and to deliver the placenta by our own effort all require forethought, commitment, and that we choose birth attendants that are comfortable and experienced with these choices. (vaccinationinformationnetwork.com)
  • Traditionally, ergot alkaloids have been used in the management of migraines and applied for oxytocic purposes during childbirth. (qualitycoursework.com)
  • Use of oral oxytocics for stimulation of labor in cases of premature rupture of the membranes at term. (wikipedia.org)
  • Long-term carcinogenicity and fertility studies have not been conducted with CERVIDIL. (cervidil.com)
  • As will become obvious, there are many areas in which basic knowledge about the mechanisms of action of psychoactive drugs does not exist. (druglibrary.net)
  • How has SMGL influenced changes in government policies and guidelines that are critical to long-term improvements in maternal and newborn survival? (ghspjournal.org)
  • Each major therapeutic area is considered by class of activity of drug. (taylorfrancis.com)
  • a synthetic drug used to disperse fluids, e.g. urine, retained in the body. (absp.org.uk)
  • GLOSSARY ********** This is provided as handy means of finding out what specific herbal terms mean. (works.org)
  • These symptoms are very basic and common ones, so their prevalence is quite high, owing to the increase in the demand for the antihistamine drugs. (forextv.com)
  • Due to the convenience and effectiveness of oral antihistamine drugs, this segment dominated the market with a 48.2 % market share. (forextv.com)
  • an antihistamine drug used in sleeping tablets. (absp.org.uk)
  • an antihistamine drug used to relieve travel and postoperative sickness. (absp.org.uk)
  • Over the years, the labor stage has been drastically reduced from as much as 36 hours in the 1950s, to 24 hours in the 1960s, to less than 12 hours through use of drugs in the 1970s when AML was introduced. (vaccinationinformationnetwork.com)
  • Obstetric services are a priority area where the private sector can make an important contribution in terms of skilled providers. (bvsalud.org)
  • Drug Benefits and Risks: International Textbook of Clinical Pharmacology - Revised 2nd Edition. (wikipedia.org)
  • It is also the prototype for neuroprotective drugs that increase resistance to ischemic injuries. (patentpc.com)
  • Implementation of these areas remains as long- term objectives for the present policy. (who.int)
  • It is a long-term condition affecting both children and adults. (forextv.com)
  • Collaborative analysis of long-term anti-coagulant administration after acute myocardial infarction. (jameslindlibrary.org)
  • General guidelines for choosing dosages and types of drugs within a class are lacking. (medscape.com)
  • Increased NO production may facilitate administration of drugs not easily absorbed to the brain and/or reduce serum concentrations necessary for desired physiological effects. (patentpc.com)
  • The FDA (Food and Drugs Administration in the U.S.) sees the plant as safe and well stated in the GRAS list (Generally Recognized as Safe). (botanical-online.com)
  • Life-Saving Drugs (LSDs) are the drugs that save someone's life, require immediate administration in most of the cases, as they. (fistofawesome.com)
  • Obtain patient history, including drug history and any known allergies. (medicscientist.com)
  • This beneficial role can be detrimental if the drug cannot cross the blood-brain border. (patentpc.com)