Drugs induced autoimmune hepatitis. Medical search. Frequent questions

Note that ASMAs occur in low titers in healthy children and patients with viral hepatitis and other diseases that do not affect the liver. (medscape.com)
You cannot get viral hepatitis from being near someone with the virus, or from touching them or something they have touched. (britishlivertrust.org.uk)
The most common form of viral hepatitis in the UK is hepatitis C. This can be spread via needles. (britishlivertrust.org.uk)
And some people have viral hepatitis as a result of medical procedures such as blood transfusions that took place before safety measures were introduced in 1991. (britishlivertrust.org.uk)
Viral hepatitis. (nih.gov)
Such symptoms are clinically indistinguishable in the individual patient from other types of acute viral hepatitis. (logicalimages.com)
Viral hepatitis is an infection that is caused by viruses, which mainly affect the hepatocytes, also known as the liver cells. (com.ng)
Since we are focused only on viral hepatitis I will stop here for now. (com.ng)
Among viral hepatitis, the most common viruses are the A, B, and C viruses. (com.ng)
Before I answer this question, it is good we know that most people with viral hepatitis at an early stage don't show any symptoms, which is known as the asymptomatic stage. (com.ng)
For epidemiology, at least 1 person dies from viral hepatitis every 30secons which is even greater than that of HIV. (com.ng)
Viral hepatitis is rarely transmitted by kissing, holding hands, sharing eating utensils, or even mosquito bites. (com.ng)
It is therefore important to rule out other causes of liver disease like viral hepatitis, alcoholic hepatitis and drug-induced hepatitis while making the diagnosis of autoimmune hepatitis. (hepatitisprohelp.com)
Viral hepatitis was the most common causefound in 22 (36.7%) cases. (edu.pk)
Conclusion: Viral hepatitis is the leading cause of chronic liverdisease in children, with the highest incidence of chronic Hepatitis C followed by metabolic disorders(glycogen storage disease and Wilson disease) and biliary atresia. (edu.pk)
Chronic viral hepatitis was mostprevalent between 11 months to 12 years of age. (edu.pk)
Serology Acute viral hepatitis is diffuse liver inflammation caused by specific hepatotropic viruses that have diverse modes of transmission and epidemiologies. (msdmanuals.com)
In such a setting, laboratory tests for drug-induced hepatitis, metabolic disease, viral hepatitis, and various autoimmune diseases may also be obtained to assist in establishing the diagnosis. (medscape.com)

Autoimmune hepatitis may present as acute or chronic hepatitis or as well-established cirrhosis. (medscape.com)
Prolongation of the international normalized ratio (INR) and hypoalbuminemia: These markers of severe hepatic synthetic dysfunction may be observed in patients with acute severe autoimmune hepatitis or decompensated cirrhosis. (medscape.com)
Liver transplantation can save the lives of patients dying from decompensated cirrhosis caused by autoimmune hepatitis. (medscape.com)
Hepatitis is an inflammatory condition of the liver that can be self-limiting or progress to fibrosis, cirrhosis or cancer. (usp.br)
Individuals with mild to moderate chronic hepatitis C infection are generally asymptomatic, while decompensated cirrhosis may be associated with fatigue, jaundice, loss of muscle mass (weight loss), ascites, edema, bruising (coagulopathy), gastrointestinal bleeding, and hepatic encephalopathy. (logicalimages.com)
High levels of AST in the blood may be a sign of hepatitis, cirrhosis, mononucleosis, or other liver diseases. (elispot.biz)
formerly known as primary biliary cirrhosis) is an autoimmune liver disorder characterized by the progressive destruction of intrahepatic bile ducts, leading. (msdmanuals.com)
Primary biliary cirrhosis (PBC) is a progressive inflammatory liver disease characterized by autoimmune-mediated destruction of intrahepatic bile ducts. (medscape.com)
The term "chronic liver disease" encompasses a large number of conditions having different etiologies and existing on a continuum between hepatitis infection and cirrhosis. (aafp.org)
2 From 75 to 80 percent of persons with hepatitis C virus infection develop chronic hepatitis (diagnosed by the presence of persistently elevated liver injury test results for more than six months), and more than 25 percent develop cirrhosis within 30 to 40 years. (aafp.org)
Worldwide, hepatitis B is another major cause of cirrhosis and hepatocellular carcinoma. (aafp.org)
Other recognized categories of chronic liver disease include conditions induced by toxins or drugs (e.g., alcohol) and autoimmune chronic liver diseases such as primary sclerosing cholangitis, primary biliary cirrhosis and autoimmune hepatitis. (aafp.org)
8 Although each form of liver disease has a distinct natural history, most forms progress slowly from hepatitis to cirrhosis, often over 20 to 40 years. (aafp.org)
Hence, it is imperative to prevent further exacerbation of the disease and to optimize the length of time between hepatitis and the development of cirrhosis. (aafp.org)
Alcohol consumption has been associated with alcoholic hepatitis, fatty infiltration of the liver, accelerated progression of liver disease, a higher frequency of cirrhosis, a higher incidence of hepatocellular carcinoma, and death. (aafp.org)
Investigators in one study 12 found that the effect of alcohol in patients with hepatitis C virus infection is not merely additive but synergistic, and that even moderate use of alcohol can hasten the development of cirrhosis. (aafp.org)

Drug-induced liver injury should be considered in any acute liver injury or jaundice without evidence of biliary obstruction. (bsg.org.uk)
Methods We systematically compared liver irAEs with AILD, namely autoimmune hepatitis (AIH) and primary biliary cholangitis, regarding their clinical, laboratory, and histological features. (bmj.com)
Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases. (cdc.gov)

Symptoms and physical examination findings may stem from extrahepatic diseases associated with autoimmune hepatitis. (medscape.com)
The disease often is associated with other autoimmune diseases, but autoimmune hepatitis cannot be explained on the basis of chronic viral infection, alcohol consumption, or exposure to hepatotoxic medications or chemicals. (medscape.com)
PBC is seen primarily in middle-aged women, and in those afflicted with other autoimmune diseases. (wikipedia.org)
The 2019 American Association for the Study of Liver Diseases (AASLD) practice guideline states: "The diagnosis of autoimmune hepatitis cannot be made without liver biopsy and compatible histologic findings. (medscape.com)
Ye is a Professor of Autoimmune liver diseases and Translational Hepatology at the Institute of Immunology and Immunotherapy, University of Birmingham and Consultant Hepatologist at the Queen Elizabeth Hospital where he specialises in the management of autoimmune liver diseases, immune mediated liver injury and liver transplantation. (birmingham.ac.uk)
His team spearhead the bench to bedside regulatory T cells immunotherapy in autoimmune liver diseases. (birmingham.ac.uk)
His group basic science research aims to dissect the pathogenesis mechanism of autoimmune liver diseases, immune mediated and drug induced/check point inhibitors liver injury with TransOMICS approach, deep immune profiling and develop personalised and stratified therapies. (birmingham.ac.uk)
His team develop and deliver translational GMP Regulatory T clinical trials in autoimmune liver diseases. (birmingham.ac.uk)
During his PhD he dissected the recruitment mechanism of regulatory T cells and developed isolation of GMP-grade regulatory T cells to apply as new therapy in autoimmune liver diseases and liver transplantation. (birmingham.ac.uk)
His research group focus on basic discovery science in autoimmune liver diseases, develop translational cellular therapy and practice precision medicine. (birmingham.ac.uk)
Ye and his team explore the underlying immune balance in the early and late stage of autoimmune liver diseases. (birmingham.ac.uk)
Furthermore, Th22 cells are associated with inflammatory conditions and numerous autoimmune diseases, such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) [ 12 , 13 ]. (hindawi.com)
Regulatory T cells (Tregs) are important regulators of immune tolerance to self-antigens [ 14 , 15 ], and their impairment has been associated with the development of autoimmune diseases [ 16 , 17 ]. (hindawi.com)
Hepatobiliary tract diseases: infantile cholestasis, autoimmune and drug induced hepatitis, others. (case.edu)
Many rheumatic diseases and autoimmune disorders have common symptoms. (flebo.in)
It is difficult to suspect autoimmune hepatitis only based on the symptoms since several liver diseases cause similar symptoms. (hepatitisprohelp.com)
Your childs health care provider will do several tests to look for autoimmune hepatitis and other related diseases. (hepatitisprohelp.com)
Make informed treatment decisions with the latest clinical trial results for portal hypertension, autoimmune liver diseases, acute liver failure, and hepatic infections. (booksmedicos.org)
Their immune-boosting quality has one major drawback, their proclivity to induce a broad array of immune-related adverse events (irAEs) affecting, among others, the liver and sharing some similarities with classic autoimmune liver diseases (AILD).We aimed to compare clinical, laboratory and histological features of patients with liver-related irAEs and AILD. (bmj.com)
However, few studies exist extensively characterizing these injuries and even fewer comparing them to classic autoimmune liver diseases (AILD). (bmj.com)
Support of precision medicine through risk-stratification in autoimmune liver diseases - histology, scoring systems, and non-invasive markers. (cdc.gov)
Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. (bvsalud.org)
who are latently infected with an on- Certain pharmaceutical drugs, Immunosuppression as a medi- cogenic virus are at greatly increased ionizing and ultraviolet radiation, cal therapy is used to treat autoim- risk for developing virus-related or infection with certain viruses mune diseases such as lupus ery- cancers when they become immu- and parasites can cause immu- thematosus or rheumatoid arthritis. (who.int)

We screened 1,200 living heart, lung, liver, and kidney transplant recipients for hepatitis E virus infection by reverse transcription PCR. (cdc.gov)
This immunocompromised population is at risk for hepatitis E virus infection. (cdc.gov)
Hepatitis E virus (HEV) can cause acute or chronic infection in humans. (cdc.gov)
Interpretation of perinatal clinical pathology tests: amniotic fluid chemistry, Kleihauer-Betke test, maternal-fetal antibody testing, serology of infection and autoimmune disorders, blood gas interpretation. (case.edu)
ABSTRACT There is strong epidemiological evidence linking hepatitis C virus (HCV) infection and diabetes. (who.int)
Terms and Abbreviations Used in This Publication Acute hepatitis C Newly acquired symptomatic hepatitis C virus (HCV) infection. (cdc.gov)
Hepatitis C is an infection of the liver with the hepatitis C virus (HCV), an RNA virus related to the flaviviruses. (logicalimages.com)
Following exposure to HCV, the incubation time for acute hepatitis C is 2-24 weeks (average 4-12 weeks), thus intermediate between incubation times for hepatitis A and B . In 70%-80% of cases, acute HCV infection is asymptomatic or leads to mild disease. (logicalimages.com)
Approximately 15%-25% of patients clear HCV infection following acute hepatitis. (logicalimages.com)
Fulminant hepatitis caused by acute HCV infection is very uncommon, but its risk is higher in HIV-infected men who have sex with men (MSM). (logicalimages.com)
These extrahepatic manifestations are considered secondary to immune-mediated mechanisms, either lymphoproliferative or autoimmune in nature, although direct infection of extrahepatic tissue cells by HCV has been documented. (logicalimages.com)
Hepatitis C virus infection is the most frequent cause of chronic liver disease and the most common indication for liver transplantation. (aafp.org)
therefore, patients with hepatitis C infection should abstain from alcohol use. (aafp.org)
Hepatitis C is a common parenterally acquired infection that affects an estimated 4 million persons in the United States. (aafp.org)
2 Hepatitis C virus infection is the leading cause of chronic liver disease and the reason for 30 to 35 percent of liver transplantations. (aafp.org)
3 - 5 Thus far, treatments for hepatitis C virus infection have been somewhat disappointing, with the best response rates to interferon and ribavirin therapy reported at 40 percent. (aafp.org)
Many patients with hepatitis B virus infection fail standard therapy. (aafp.org)
Alcohol abuse and hepatitis C virus infection frequently coexist in patients with chronic liver disease. (aafp.org)

Liver biopsy and HLA genotyping can help clinical management by differentiating DILI from AIH and excluding DILI secondary to certain drugs. (bsg.org.uk)
There is no high-quality evidence that supports empirical use of steroids to treat DILI unless in scenarios when auto-immune hepatitis cannot be excluded. (bsg.org.uk)
Idiosyncratic drug-induced liver injury (DILI) is an unpredictable type of liver injury following exposure to medication within the recommended dose which is distinctive from liver injury caused by drug overdosage, commonly caused by paracetamol overdose (POD). (bsg.org.uk)
The study revealed that the mindless consumption of giloy was contributing to liver toxicity, specifically drug-induced liver injury (DILI). (thewire.in)
Pharmacogenomics of drug-induced liver injury (DILI): Molecular biology to clinical applications. (cdc.gov)

HCV can cause acute or chronic hepatitis and very uncommonly fulminant hepatitis. (logicalimages.com)
Three days after admission, he entered hepatic coma (grade III) and prothrombin activity decreased (23.2%) , compatible with fulminant hepatitis. (bvsalud.org)
A variety of clinical presentations can be observed ranging from mild, almost subclinical disease to fulminant hepatitis [ 1 ]. (e-cmh.org)

Autoimmune hepatitis (AIH) is a type of autoimmune inflammatory liver disease characterized by hypergammaglobulinaemia, circulating autoantibodies, and the liver injury with elevated levels of serum liver enzymes [ 1 ]. (hindawi.com)
Autoimmune Hepatitis: Serum Autoantibodies in Clinical Practice. (nih.gov)
Autoimmune hepatitis is an organ specific autoimmune disease that manifests as a chronic inflammatory disease of the liver, typically characterized by periportal inflammation, elevated autoantibodies and hypergammaglobulinemia. (e-cmh.org)

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. (nih.gov)
He also leads the UK drug induced liver injury immunology work stream with his team and AIH Immunology work. (birmingham.ac.uk)
Drug Induced Liver Injury is a rare side effect that some people get after taking medicine prescribed by their doctor. (britishlivertrust.org.uk)
Thus, to evaluate the therapeutic potential of A. aegypti mosquito saliva in acute liver failure, we employed a well-established model for the study of autoimmune hepatitis, acute experimental hepatitis induced by concanavalin A (Con A), and a model of hepatotoxicity induced by acetaminophen (APAP) commonly employed to study drug-induced liver injury. (usp.br)
Acute cases may appear histologically indistinct to drug induced liver injury [ 9 ]. (e-cmh.org)
Known causes of acute liver failure include autoimmune hepatitis, drug-induced liver injury, hepatitis A and B, and acetaminophen poisoning. (rejuvenation-science.com)
The role of the early growth response-1 (EGr-1) transcription factor is thought to be essential for ethanol-induced fatty liver injury in mice. (medscape.com)
An aggressive form of chronic hepatitis involving extensive liver damage and cell injury beyond the portal tract. (bvsalud.org)

Autoimmune hepatitis is a chronic disease of unknown cause. (medscape.com)
Autoimmune hepatitis is a chronic disease of unknown cause, characterized by continuing hepatocellular inflammation and necrosis. (medscape.com)

Approximately one third of patients present with symptoms of acute hepatitis marked by fever, hepatic tenderness, and jaundice. (medscape.com)
Clinicians must consider the diagnosis of autoimmune hepatitis in any patient who presents with abnormal liver chemistries, acute hepatitis, or acute liver failure (defined by the new onset of coagulopathy and hepatic encephalopathy). (medscape.com)
The classical histological hallmark of AIH is interface hepatitis characterised by inflammation and erosion at the junction of the hepatic parenchyma with the portal tracts. (e-cmh.org)
[ 11 ] In addition, a minority of patients with fulminant hepatic failure from various causes, such as drug-induced liver damage and hepatitis A and B, are reported to have transiently detectable levels of serum antimitochondrial antibody that disappear within one year. (medscape.com)
The mechanism for the synergistic effect of alcohol and hepatitis C virus is not fully understood, but it has been attributed to the effects of alcohol on viral replication and the immune system, hepatic iron content and hepatic regeneration. (aafp.org)

It's known that in about 10 to 15 percent of people with autoimmune hepatitis, the condition is triggered by drugs or supplements, the report said. (livescience.com)
But no government agency has warned that people with autoimmune disorders should avoid giloy - a reckless position exacerbated by uncritical media coverage. (thewire.in)

While serologic tests may help the clinician make a correct a diagnosis of autoimmune hepatitis, it should be recalled that liver biopsy plays a pivotal role in the evaluation. (medscape.com)
Autoimmune hepatitis is an unlikely diagnosis in patients who have acute hepatitis without hypergammaglobulinemia. (medscape.com)

Further tests revealed the woman had a condition called autoimmune hepatitis , in which the body's immune system attacks the liver, causing inflammation and liver damage, according to the NIH . (livescience.com)
Hopefully, this article has given you hope and several major action steps to reduce inflammation and heal autoimmune disease. (hepatitisprohelp.com)

For more than four decades, corticosteroids, either alone or in combination with azathioprine, have been the mainstays of drug therapy for patients with autoimmune hepatitis. (medscape.com)
[ 2 ] Budesonide (in combination with azathioprine) is now considered to be first-line therapy for autoimmune hepatitis. (medscape.com)
However, the risk of primary cancer clinically as an immunosuppressant maceutical drugs ciclosporin and in the transplant recipient increases to treat certain autoimmune diseas- azathioprine. (who.int)

While some are inherited, sometimes mutations due to medication or excessive substance abuse can lead to the development of autoimmune disorders. (flebo.in)

Hellenic Association for the Study of the Liver Clinical Practice Guidelines: Autoimmune hepatitis. (cdc.gov)

M5 - systemic lupus erythematosus and undifferentiated collagenosis, autoimmune haemolytic anaemia. (wikipedia.org)

Autoimmune disorders are genetic in nature. (flebo.in)
1 People with type 2 can also have any of the above autoimmune disorders. (hepatitisprohelp.com)
According to doctors, giloy is forbidden for people who suffer from autoimmune disorders, and can lead to death if it is consumed in sufficiently large quantities. (thewire.in)
However, the same mechanism can cause significant liver toxicity, and we recommend that caution be exercised in the use of this herb, especially in those predisposed to autoimmune disorders. (thewire.in)

Make optimal use of genetic testing to assess your patients' risk of metabolic liver disease and to personalize treatment regimens for chronic hepatitis C. (booksmedicos.org)

and · antiviral therapy during pregnancy for the prevention of perinatal hepatitis B virus (HBV) transmission. (cdc.gov)

The aetiology of autoimmune hepatitis (AIH) is uncertain but the disease can be triggered in susceptible patients by external factors such as viruses or drugs. (wjgnet.com)
I too have autoimmune hep and smooth muscle anitbodies are a marker in determining the disease. (healingwell.com)
The work during his MRC funded clinician scientist led to the first in autoimmune liver disease early phase trial on GMP Regulatory T cells homing to the human liver. (birmingham.ac.uk)
In 2019, Ye received Sir Jules Thorn Programme Grant Award to develop and deliver Regulatory T cells therapy in autoimmune liver disease. (birmingham.ac.uk)
Moreover, a murine model of experimental autoimmune hepatitis (EAH) was also established and used to investigate the function of Treg-Th1-Th17-Th22 cells in disease progression. (hindawi.com)
People who have a direct relative suffering from autoimmune disease are also requested to get the ANA test done if any of the above-mentioned symptoms are noticed. (flebo.in)
In the case of autoimmune disease, the immune system considers the healthy cells of the body to be harmful antigens and thus, produces specific antibodies to counter these cells. (flebo.in)
In these criteria, patients without histological findings of hepatitis are included in the disease entity of "acute liver failure", as in Europe and the USA. (elsevierpure.com)
Out of these 22 patients with viral aetiology 19 (31.66%) patients hadHepatitis C and 3 (5%) had Hepatitis B. Glycogen storage disease was seen in 8.3% cases, and biliaryatresia and Wilson disease in 6.7% each. (edu.pk)
Tinospora cordifolia (giloy) consumption seems to induce an autoimmune-like hepatitis or unmask an underlying autoimmune chronic liver disease, which may support its immune stimulant mechanism. (thewire.in)
Autoimmune hepatitis (AIH) is an uncommon though serious and potentially life-threatening disease which requires prompt recognition and treatment by experienced hepatologists. (e-cmh.org)
A further third present with acute icteric hepatitis, though the majority of patients have subacute disease [ 6 ]. (e-cmh.org)

antigen-negative hepatitis after treatment of malignancy. (edu.pk)

Background and Aim: We investigated the efficacy and effectiveness of entecavir in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients. (aurorakinaseb.com)

It is associated with biochemical and/or histological features that are indistinguishable from AIH, including the presence of anti-nuclear antibodies, hyper-gammaglobulinemia and interface hepatitis with plasma cells on histology. (bsg.org.uk)

20 g/day of alcohol consumption, viral, autoimmune, and drug-induced hepatitis, or history of use of methotrexate or cyclosporine were excluded from the study. (medpagetoday.com)
It is widely believed that alcohol and the hepatitis C virus act together to promote the development and progression of liver damage. (aafp.org)

Isolated cases of an autoimmune hepatitis-like syndrome associated with simvastatin therapy have been reported, some of which did not reverse completely with discontinuation, resulting in a chronic hepatitis requiring long term immunosuppressive therapy. (nih.gov)

Genetic risk factors for autoimmune hepatitis: implications for phenotypic heterogeneity and biomarkers for drug response. (cdc.gov)
Leveraging Social Networking Sites for an Autoimmune Hepatitis Genetic Repository: Pilot Study to Evaluate Feasibility. (cdc.gov)

It's unclear how drugs or supplements trigger drug-induced autoimmune hepatitis, but it's thought that in some cases, the breakdown of drugs may lead to the formation of molecules that trigger an immune reaction, according to the NIH . (livescience.com)
Autoimmune hepatitis is caused by your own immune system getting confused and attacking your liver. (britishlivertrust.org.uk)

HBV Hepatitis B virus. (cdc.gov)
HCV Hepatitis C virus. (cdc.gov)
HCV RNA Hepatitis C virus ribonucleic acid. (cdc.gov)
Passionate about reducing the risk of the hepatitis virus, the initiative has organized outreach and held several seminars to enlight people about hepatitis, its cause, and preventive measures, plus carried out free screening for both hepatitis B and C, gave the free first dose of hepatitis B vaccine amidst other activities. (com.ng)
Can you explain the hepatitis virus? (com.ng)
What are the causes of the hepatitis virus? (com.ng)
What are the various symptoms of the hepatitis virus? (com.ng)
What are the latest research findings on the hepatitis virus? (com.ng)
Hepatitis virus does not spread through breast milk, especially hepatitis c. (com.ng)
transmission of hepatitis B virus in three generations of a lowprevalence population. (edu.pk)
Because superinfection with hepatitis A or B virus can lead to liver failure, vaccination is recommended. (aafp.org)
Hepatitis B virus (HBV) is transmitted via blood or sexual contact. (cdc.gov)
la hepatitis crónica puede estar causada por virus, fármacos, enfermedades autoinmunitarias y otros factores desconocidos. (bvsalud.org)

Liver biopsy remains an important part of the diagnostic workup of patients with suspected autoimmune hepatitis. (medscape.com)

The anti-nuclear antibody test or the ANA test is prescribed as part of a screening test to check if a person is suffering from an autoimmune disorder or not. (flebo.in)

In 10%-20% of cases, autoimmune hepatitis may present with symptoms like an acute hepatitis. (hepatitisprohelp.com)

Other less commonly found cases were autoimmune hepatitis,TORCH infections, hepatoma and drug induced hepatitis (1.7% each). (edu.pk)

For hepatitis as will just mention like, the schedule for the hepatitis B vaccine is now day 0, 1 month then 6 months, not the former monthly dose. (com.ng)

Many mechanisms of ethanol-induced fatty liver have been proposed. (medscape.com)
This may be related to mitochondrial proteins that regulate apoptosis and necrosis and that are shown to be induced in mouse fatty liver models. (medscape.com)

Anatomy1

Organisms8

Diseases29

Chemicals and Drugs25

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Health Care1

Geographicals1

Viral hepatitis18

Cirrhosis16

Biliary3

Diseases23

Infection18

DILI5

Fulminant hepatitis3

Autoantibodies3

Injury8

Chronic disease2

Hepatic5

People with autoimmune2

Diagnosis2

Inflammation2

Azathioprine3

Development of autoimmune1

Clinical1

Lupus1

Disorders4

Metabolic1

Perinatal hepatitis1

Disease12

Antigen1

Hepatocellular carcinoma1

Histological1

Alcohol2

Immunosuppressive1

Genetic2

Immune2

Virus13

Workup1

Antibody1

Present with symptoms1

Commonly1

Vaccine1

Fatty liver2