Drugs etoposide. Medical search. Frequent questions

The oncologist there started me on a chemotherapy regimen called R-CHOP, which includes the drugs rituximab, cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone. (mdanderson.org)
I. To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/ carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the event-free survival (EFS) of patients with newly diagnosed stage 4 diffuse anaplastic Wilms tumor (DAWT) as compared to historical controls. (clinicaltrials.gov)
To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the EFS of patients with standard-risk relapsed favorable histology Wilms tumor (SRrFHWT) as compared to historical controls. (clinicaltrials.gov)
I. To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the overall survival (OS) of patients with newly diagnosed stage 4 DAWT as compared to historical controls. (clinicaltrials.gov)
To establish EFS and OS for high-risk (HRrFHWT) and very high risk (VHRrFHWT) relapsed favorable histology Wilms tumor treated with ifosfamide/carboplatin/etoposide alternating with cyclophosphamide/ topotecan. (clinicaltrials.gov)
Some examples of oral chemo drugs for breast cancer include: cyclophosphamide. (knowbreastcancer.org)

Adjuvant or palliative treatment for adrenocortical carcinoma (AC) has been studied by using mitotane, cisplatin, etoposide, and doxorubicin. (medscape.com)
studies have focused on the regimen etoposide and cisplatin and on etoposide, doxorubicin, and cisplatin. (medscape.com)
Previous studies had suggested a synergism between cisplatin and etoposide, and some authors had reported interesting response rates with either of the two combinations: etoposide/cisplatin (EP)[4] or etoposide/doxorubicin (Adriamycin)/cisplatin (EAP). (cancernetwork.com)

Etoposide, sold under the brand name Vepesid among others, is a chemotherapy medication used for the treatments of a number of types of cancer including testicular cancer, lung cancer, lymphoma, leukemia, neuroblastoma, and ovarian cancer. (wikipedia.org)

First-line therapy in ES-SCLC currently consists of chemotherapy, combining a platinum drug with either etoposide or irinotecan as a possible alternative. (ersjournals.com)

This combination contains the targeted therapy drug rituximab and the chemotherapy drugs ifosfamide, carboplatin, and etoposide phosphate. (cancer.gov)
I. To describe renal toxicity of ifosfamide/carboplatin/etoposide in HRrFHWT and VHRrFHWT patients using conventional and novel biomarkers of renal toxicity (urine NGAL, cystatin C and Kim1) in the context of the chemotherapy regimens used on this study. (clinicaltrials.gov)

This is a case report of a 77-year-old Spanish male patient with localized SCC of the colon, who presented a pathological complete response in the surgical specimen after neoadjuvant chemotherapy with cisplatin and etoposide. (mdpi.com)

It is often given in combination with other drugs (such as bleomycin in treating testicular cancer). (wikipedia.org)
Standard management in the UK for high-risk stage 1 nonseminoma germ cell tumours of the testis (NSGCTT) is two cycles of adjuvant bleomycin, etoposide (360 mg/m 2 ), and cisplatin (BE 360 P) chemotherapy, or surveillance. (nih.gov)
One cycle comprising bleomycin 30000 IU on days 1, 8, and 15, etoposide 165 mg/m 2 on days 1-3, and cisplatin 50 mg/m 2 on days 1-2, plus antibacterial and granulocyte colony stimulating factor prophylaxis. (nih.gov)
The combination used most often is PEB (or BEP), and includes the chemo drugs cisplatin, etoposide, and bleomycin. (cancer.org)

Here we'll look at the drugs frequently used against diffuse large B-cell lymphoma , follicular lymphoma and Hodgkin's lymphoma . (lymphomainfo.net)
Impact on survival of addition of etoposide to primary chemotherapy in diffuse large B-cell lymphoma: a Swedish Lymphoma Registry study. (lu.se)

What are some of the most common chemo drugs? (medicalnewstoday.com)
Has anyone had any of these chemo drugs in their teatment? (cancer.org)
As you have said most of us are not on your particular chemo drugs. (cancer.org)
I hope you have minimal side effects from your chemo drugs. (cancer.org)

Dysgerminomas are usually very sensitive to chemo, and can sometimes be treated with the less toxic combination of carboplatin and etoposide. (cancer.org)
Phase I Study of Entinostat, Atezolizumab, Carboplatin, and Etoposide in Previously Untreated Extensive-Stage Small Cell Lung Cancer, ETCTN 10399. (cdc.gov)

2023. https://emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/109244/11.0/etoposide. (unboundmedicine.com)
Medically reviewed by Drugs.com on Jun 21, 2023. (drugs.com)
Invest New Drugs;2023 Oct 14. (bvsalud.org)

Etoposide is a glycosidic derivative of podophyllotoxin that exerts a cytotoxic effect by stabilizing the normally transient covalent intermediates formed between the DNA substrate and topoisomerase II. (medscape.com)
Etoposide is in the topoisomerase inhibitor family of medication. (wikipedia.org)
Etoposide forms a ternary complex with DNA and the topoisomerase II enzyme, which is an enzyme that aids in relaxing negative or positive supercoils in DNA. (wikipedia.org)
We are using this deletion set to identify all yeast genes that confer sensitivity to drugs targeting DNA topoisomerase II. (aacrjournals.org)
Unfortunately, most drugs that target DNA topoisomerase II do not accumulate in wild type yeast cells to high enough. (aacrjournals.org)
Our results may also provide important clues to the differences in cellular responses to drugs targeting such as camptothecin, that target topoisomerase I and drugs such as etoposide that target topoisomerase II. (aacrjournals.org)
Etoposide inhibits topoisomerase II and causes DNA strand breakage, causing cell proliferation to arrest in the late S or early G2 portion of the cell cycle. (medscape.com)

It is used in form of its salt etoposide phosphate. (wikipedia.org)

Combinations usually work better than single drugs because different drugs kill cancer cells in different ways. (cancer.gov)
Other drug combinations may be used to treat cancer that has recurred (come back) or hasn't responded to treatment. (cancer.org)
If stomach cancer does not respond to drugs used in earlier treatments or if it comes back, different drugs or combinations may be used. (cancer.ca)

A few years ago, we performed a phase II trial with the FLEP regimen, in which fluorouracil (5-FU) and leucovorin are combined with etoposide and cisplatin (Platinol). (cancernetwork.com)
In 1989, Preusser et al[3] reported a 57% response rate with the FLEP regimen-5-FU, leucovorin, etoposide, and cisplatin (Platinol). (cancernetwork.com)
The FLEP regimen we used consisted of leucovorin 300 mg/m 2 /day, followed by etoposide 100 mg/m 2 /day, 5-FU 500 mg/m 2 /day, and cisplatin 30 mg/m 2 /day, all given on days 1 through 3 and repeated every 28 days. (cancernetwork.com)
If your relapse occurs within 6 months of your treatment, it's generally recommended to try a different regimen with a single chemotherapy drug. (healthline.com)
You can read more about each of the drugs by clicking on the name of the regimen. (lymphomainfo.net)
This trial may help doctors find out what effects, good and/or bad, regimen UH-3 has on patients with newly diagnosed DAWT and standard risk relapsed FHWT (those treated with only 2 drugs for the initial WT) and regimen ICE/Cyclo/Topo has on patients with high and very high risk relapsed FHWT (those treated with 3 or more drugs for the initial WT). (clinicaltrials.gov)

Most people receive chemotherapy drugs through an injection or infusion. (medicalnewstoday.com)

A combination of chemotherapy drugs is often administered together with radiation therapy in people with limited stage SCLC to try to cure the cancer. (healthline.com)
Doctors usually treat SCLC with a combination of chemotherapy drugs. (healthline.com)
The first-line treatment of ES-SCLC currently consists of chemotherapy with a platinum derivative and etoposide, a combination that was first reported to be effective in the treatment of SCLC in 1985 8 , 9 . (ersjournals.com)
This clinical study examined the effectiveness of anlotinib plus etoposide for maintenance therapy in ES-SCLC. (bvsalud.org)
Maintenance anlotinib plus etoposide achieves promising PFS and OS in clinical ES-SCLC. (bvsalud.org)

Etoposide (Lastet (50 mg)) is an anti-cancer agent, prescribed for lung cancer and testicular cancer. (medindia.net)
Etoposide is used as a form of chemotherapy for cancers such as Kaposi's sarcoma, Ewing's sarcoma, lung cancer, testicular cancer, lymphoma, nonlymphocytic leukemia, and glioblastoma multiforme. (wikipedia.org)
Chemotherapy uses drugs to kill testicular cancer cells. (epnet.com)
Drugs approved for testicular cancer. (epnet.com)
Available at: https://www.cancer.gov/about-cancer/treatment/drugs/testicular. (epnet.com)

Etoposide comes as a capsule to take by mouth. (medlineplus.gov)

Etoposide capsules are a cold-chain medication used for small cell lung cancer that must be stored under refrigeration between 2°C and 8°C (36°F-46°F). A specialty pharmacy reported an error that resulted in a carton of etoposide 50 mg capsules being left out at room temperature overnight for about 12 hours. (pharmacist.com)
Etoposide may also be used for purposes not listed in this medication guide. (exportersindia.com)
Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. (medbroadcast.com)

It is chemically similar to the anti-cancer drug teniposide, being distinguished only by a methyl group where teniposide has a thienyl. (wikipedia.org)

tell your doctor and pharmacist if you are allergic to etoposide, any other medications, or any of the ingredients in etoposide capsules. (medlineplus.gov)

The purpose of this study is to assess a new combination of chemotherapy drugs as the first treatment for children newly diagnosed with neuroblastoma that has a high risk of returning after therapy. (mskcc.org)
It may be a combination of chemotherapy drugs or chemotherapy plus immunotherapy. (healthline.com)

Etoposide is a semisynthetic derivative of podophyllotoxin from the rhizome of the wild mandrake (Podophyllum peltatum). (wikipedia.org)

CDC and others recommend oral acyclovir, oral famciclovir, or oral valacyclovir as drugs of choice for treatment of initial episodes of genital herpes and for episodic treatment or chronic suppressive therapy of recurrent genital herpes. (drugs.com)
There are two chemotherapy regimens and drugs involved in frontline therapy. (lymphomainfo.net)
The US Food and Drug Administration (FDA) has granted a third so-called Breakthrough Therapy Designation for the investigational oral. (lymphomainfo.net)
The U.S. Food and Drug Administration has announced that it has granted "Breakthrough Therapy Designation" for the investigational agent. (lymphomainfo.net)
A number of ferroptosis inducers have been proposed as potential drugs for cancer therapy. (nature.com)
Chemotherapy (chemo), hormone treatment, targeted therapy, and immunotherapy drugs can reach cancer cells almost anywhere in the body. (knowbreastcancer.org)
The chemotherapy drugs help make the cancer cells more sensitive to radiation therapy. (cancer.ca)
How often and how long chemotherapy is given depends on the type of drug or drug combination used and if radiation therapy is used at the same time. (cancer.ca)
Side effects of chemotherapy will depend mainly on the type of drug or combination, the dose, how it's given, if radiation therapy is given at the same time and your overall health. (cancer.ca)
The effectiveness or lack of a major therapeutic effect of sphingolipid modulation by some drugs as a cancer therapy and other aspects related to their mechanism of action are discussed in this review. (frontiersin.org)
After successful primary etoposide -based therapy , anlotinib was administered at 12 mg/day on days 1 to 14 of 21-day cycles until disease progression or consent withdrawal. (bvsalud.org)

Etoposide is in a class of medications known as podophyllotoxin derivatives. (medlineplus.gov)
Many other medications may also interact with etoposide, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. (medlineplus.gov)
Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in lower exposure to these medications. (medscape.com)
Avoid or substitute another drug for these medications when possible. (medscape.com)
A drug-induced reaction should be considered in any patient who is taking medications and who suddenly develops a symmetric cutaneous eruption. (medscape.com)
In 1980, 1981, and 1985, and continuously from 1989, the NAMCS encounter form included a question which asked for a listing of all drugs/medications ordered, administered or provided during the visit. (cdc.gov)

Etoposide is used to treat small cell lung cancer. (exportersindia.com)
Therapeutic effectiveness of anlotinib combined with etoposide in extensive-stage small-cell lung cancer: a single-arm, phase II trial. (bvsalud.org)

What Drugs Are Used in Chemotherapy for Lymphoma? (lymphomainfo.net)
Several different chemotherapy drugs are used in the treatment of different subtypes of lymphoma , sometimes alone and other times in combination chemotherapy regimens. (lymphomainfo.net)

Doctors take into account the person's overall health when deciding the number and dosage of chemotherapy drugs to recommend. (medicalnewstoday.com)
Side effects of chemotherapy vary based on the particular drugs, dosage, and how often you get it. (healthline.com)

Etoposide may harm the fetus. (medlineplus.gov)
Drugs are made to kill cancer, but they also harm healthy cells. (epnet.com)

The immunotherapy drug atezolizumab (Tecentriq) can be given along with combination chemotherapy. (healthline.com)

In summary, UFT/leucovorin/etoposide is effective and moderately toxic in patients with advanced gastric cancer. (cancernetwork.com)

The nickname VP-16 likely comes from a compounding of the last name of one of the chemists who performed early work on the drug (von Wartburg) and podophyllotoxin. (wikipedia.org)

Combination chemotherapy regimens are referred to by acronyms, with each letter representing a chemotherapeutic drug. (lymphomainfo.net)

All three mutants described above conferred hypersensitivity to mAMSA and etoposide. (aacrjournals.org)

If coadministration is unavoidable, monitor patients for loss of therapeutic effect of these drugs. (medscape.com)

The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have. (medlineplus.gov)
Etoposide is also sometimes used to treat certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed). (medlineplus.gov)
Cancer chemotherapy is based on an understanding of tumor cell growth and how drugs affect it. (medscape.com)
There are several main types of chemotherapy drugs that doctors use to target different types of cancer. (medicalnewstoday.com)
For example, doctors consider the type of cancer a person has and its stage before estimating which drugs will have the best response rates. (medicalnewstoday.com)
They will ultimately choose a drug with the highest response rate and longest duration for that type and stage of cancer. (medicalnewstoday.com)
Chemotherapy drugs target cells that replicate quickly, such as cancer cells. (healthline.com)
These drugs damage the DNA of cancer cells to destroy them or slow their growth. (healthline.com)
etoposide is a cancer medicine that interferes with the growth and spread of cancer cells in the body. (exportersindia.com)
When confronted with screening large panels of potential cancer drugs, HTS is definitely the way to go. (genengnews.com)
Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer. (cancer.gov)
This combination may also be used with other drugs or treatments or to treat other types of cancer. (cancer.gov)
The number of different drugs in N9 may make it less likely that the cancer will become resistant to chemotherapy. (mskcc.org)
The choice and blend of drugs will be based on your cancer type and how you react to the drugs. (epnet.com)
What are the most common drugs used for breast cancer? (knowbreastcancer.org)
What is the new breast cancer drug? (knowbreastcancer.org)
Patients with HER2-low breast cancer may have a new treatment option, the drug trastuzumab deruxtecan (T-DXd) , according to a study led by Memorial Sloan Kettering Cancer Center (MSK) breast medical oncologist Shanu Modi, who presented the findings at this year's American Society of Clinical Oncology (ASCO) meeting. (knowbreastcancer.org)
What is the most common cancer drug? (knowbreastcancer.org)
Chemotherapy uses anticancer (cytotoxic) drugs to destroy cancer cells. (cancer.ca)
This means that the drugs travel through the blood to reach and destroy cancer cells all over the body, including those that may have broken away from the primary tumour in the stomach. (cancer.ca)
These powerful drugs can stop cancer cells from growing and reproducing. (healthline.com)
The objective of this review was to analyze the results from preclinical and clinical trials of these drugs for the treatment of cancer. (frontiersin.org)
Our aim was to develop an analytical method for simultaneous detection and quantification of widely used cancer drugs to rule out accidental acute chemotherapy exposures in health care workers. (cdc.gov)

Medically reviewed by Drugs.com. (drugs.com)

The database is based on Region Stockholm's work in Sweden and may mean, for example, that information about the Wise list, the drug formulary of recommended essential medicines for the entire Stockholm healthcare region, has been included. (janusinfo.se)

Your healthcare team will consider your personal needs to plan the drugs, doses and schedules of chemotherapy. (cancer.ca)

Characteristics of the drugs themselves (e.g., generic ingredients, composition status, etc.) are obtained from the Drug Product Information File, maintained and marketed by the American Druggist Blue Book Data Center, and from the National Drug Code Directory, produced by the National Center for Drugs and Biologics of the U.S. Public Health Service. (cdc.gov)

The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. (cancer.gov)

and etoposide 100 mg/m2 IV on day 1 and then 200 mg/m2/day orally on days 2 and 3. (cancernetwork.com)

Etoposide can cause a severe decrease in the number of blood cells in your bone marrow. (medlineplus.gov)
apalutamide will decrease the level or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
enzalutamide will decrease the level or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
ivosidenib will decrease the level or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)

Antiproliferative drugs may be useful for palliating symptoms in patients with diffuse metastases. (medscape.com)
Drug of choice for serious or disseminated herpes zoster in immunocompromised patients. (drugs.com)
The US Food and Drug Administration today has approved an expanded use of Imbruvica (ibrutinib) in patients with. (lymphomainfo.net)
If concomitant use of ondansetron with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome. (nih.gov)
All patients also received etoposide at 50 mg/day on days 1 to 14 of 21-day cycles for a maximum of six cycles. (bvsalud.org)

Your doctor will help find out how many cycles are needed and which drugs will work best. (epnet.com)

Diseases7

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Phenomena and Processes3

Health Care1

Cyclophosphamide6

Doxorubicin3

Vepesid1

Irinotecan1

Ifosfamide2

Cisplatin and etoposide1

Bleomycin4

Diffuse large B-2

Chemo drugs4

Carboplatin and etoposide2

20233

Topoisomerase7

Phosphate1

Combinations3

Regimen6

Injection1

SCLC5

Testicular5

Capsule1

Medication3

Teniposide1

Capsules1

Combination of chemotherapy2

Derivative1

Therapy11

Medications6

Small cell l2

Lymphoma2

Dosage2

Harm2

Atezolizumab1

Leucovorin1

Podophyllotoxin1

Chemotherapy regimens1

Hypersensitivity1

Therapeutic effect1

Cancer23

Medically1

Medicines1

Doses1

Generic1

Interactions1

Orally1

Decrease4

Patients5

Cycles1