AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Retinal DegenerationMacular DegenerationNerve DegenerationWallerian DegenerationIntervertebral Disc DegenerationWet Macular DegenerationFrontotemporal Lobar DegenerationPhotoreceptor Cells, VertebrateIntervertebral DiscRetinaElectroretinographyRetrograde DegenerationChoroidal NeovascularizationRetinitis PigmentosaDisease Models, AnimalSpinocerebellar DegenerationsRetinal Pigment EpitheliumRetinal DrusenAxonsRhodopsinPhotoreceptor CellsEye ProteinsFluorescein AngiographyParaneoplastic Cerebellar DegenerationSubacute Combined DegenerationPigment Epithelium of EyeChoroidVisual AcuityGeographic AtrophyIntervertebral Disc DisplacementNeurodegenerative DiseasesMice, Inbred C57BLRetinal Rod Photoreceptor CellsNeuronsAtrophyMutationRetinal Cone Photoreceptor CellsFundus OculiAmyotrophic Lateral SclerosisMice, TransgenicIntravitreal InjectionsSpinal DiseasesLumbar VertebraeNicotinamide-Nucleotide AdenylyltransferaseBruch MembraneImmunohistochemistryLipofuscinAgingComplement Factor HNerve Tissue ProteinsEye Diseases, HereditaryCell DeathMice, Mutant StrainsBrainMicroscopy, ElectronOptic NervePeripherinsInclusion BodiesMotor Neuron DiseaseMotor NeuronsMacula LuteaCerebellar DiseasesRetinal Ganglion CellsMice, KnockoutLightTomography, Optical CoherenceRetinal DiseasesCartilage, ArticularCyclic Nucleotide Phosphodiesterases, Type 6Magnetic Resonance ImagingCartilage DiseasesSubstantia NigraDark AdaptationIn Situ Nick-End LabelingMice, Neurologic Mutantscis-trans-IsomerasesOsteoarthritis, SpineCell CountAxotomyAnimals, Genetically ModifiedDisease ProgressionOphthalmoscopyApoptosisRadiation Injuries, ExperimentalTime FactorsOptic Disk Drusentau ProteinsSupranuclear Palsy, ProgressiveMicroscopy, Electron, TransmissionParkinson DiseaseChoroid DiseasesFluorescent Antibody Technique, IndirectGliosisPhenotypeRats, Mutant StrainsRats, Sprague-DawleyCerebellar AtaxiaRetinal DetachmentOpsinsSpinal Cord
Retinal degenerationRisk of age-related macuMaculaPeople with macular degenerationNeovascular age-related macuCorticobasal degenerationFrontotemporal degeneration2019Brain cell degenerationBlindnessAtrophyTreatments2022RanibizumabMacular edemaInjectionsDisc degenerationIntervertebral discEyleaTherapeuticEpidemiologyLevodopaOphthalmologyAvastinResearchers analyzedDysfunctionPatientsTreatmentSymptomsOnsetPhotoreceptorsIrreversibleMiceDiseasesLucentisGeneSignificantlyBlood vesselsSyndromePathwayPathologicalStudyDeteriorationParkinson'sVEGFMedlinePlusMetabolismLipid-lowerNeurodegenerativeNervesEfficacySubsequentTherapyWeaknessVisionCommonInjuryFound
Retinal degeneration7
Risk of age-related macu2
Macula7
  • Macular degeneration involves the deterioration of the macula at the retina's center. (medicalnewstoday.com)
  • Macular degeneration (MD) usually affects older adults and results in a loss of vision in the center of the visual field (the macula) because of damage to the retina. (patientslikeme.com)
  • Macular degeneration affects the macula, part of the eye that allows you to see fine detail. (mylocalpharmacies.com)
  • AMD is characterized by progressive degeneration of the macula, the central part of the retina, leading to central vision loss. (delveinsight.com)
  • Macular degeneration occurs when a part of the retina called the macula degrades. (lensshopper.com)
  • Dry, or non-neovascular macular degeneration occurs when aging macular issues begin to thin out, or pigment begins to build up in the macula. (lensshopper.com)
  • Age-related macular degeneration (AMD) causes progressive damage to the macula, the central and most vital area of the retina, resulting in gradual loss of central vision. (msdmanuals.com)
People with macular degeneration2
Neovascular age-related macu4
  • Several companies are in the race to introduce Lucentis biosimilar for monthly treatment of neovascular age-related macular degeneration treatment (nAMD), with plans to bring introduce it into the market during the forecast period, such as Samsung Bioepis, SB11 and bioeq, FYB201. (medgadget.com)
  • Aims To determine the prevalence of polypoidal choroidal vasculopathy (PCV) in patients with presumed neovascular age-related macular degeneration (AMD) who were considered poor responders to ranibizumab. (bmj.com)
  • Antivascular endothelial growth factor (VEGF) agents, including ranibizumab, aflibercept and bevacizumab, are currently the standard option for the treatment of neovascular age-related macular degeneration (AMD). (bmj.com)
  • What do we currently know about the safety of recently approved drugs and devices for the treatment of neovascular age-related macular degeneration? (medscape.com)
Corticobasal degeneration3
  • Corticobasal degeneration (CBD), a sporadic neurodegenerative 4-repeat tauopathy, is a pathologically defined entity associated with several clinical phenotypes. (medscape.com)
  • Typical autopsy findings in corticobasal degeneration (CBD) include asymmetric frontoparietal cortical atrophy. (medscape.com)
  • They include multiple system atrophy (MSA), progressive supranuclear palsy (PSP ), corticobasal degeneration (CBD) and Dementia with Lewy bodies (DLB). (parkinson.ca)
Frontotemporal degeneration2
  • The most characteristic are frontotemporal degeneration spectrum disorders, but Alzheimer disease and rare disorders such as Creutzfeldt-Jakob disease, CNS Whipple disease, and Niemann-Pick disease type C can be associated with corticobasal syndrome. (medscape.com)
  • Amyotrophic lateral sclerosis & frontotemporal degeneration 2023 9 1-10. (cdc.gov)
20193
  • In August 2019, FDA approved the use of pretomanid 200mg in combination with bedaquiline and linezolid (BPaL) in adults with pulmonary extensively drug resistant (XDR), treatment-intolerant, or nonresponsive multidrug-resistant (MDR) tuberculosis (TB) [5 ]. (cdc.gov)
  • On August 14, 2019, the Food and Drug Administration (FDA) approved use of pretomanid with bedaquiline and linezolid (BPaL) as a treatment regimen for pulmonary MDR TB additionally resistant to at least one fluoroquinolone or injectable medication and for pulmonary MDR TB that is treatment-intolerant/nonresponsive (TI/NR MDR TB). (cdc.gov)
  • The age-related macular degeneration market report provides current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted 7MM age-related macular degeneration market size from 2019 to 2032. (delveinsight.com)
Brain cell degeneration1
  • the authors showed this to be protective against brain cell degeneration. (webwire.com)
Blindness6
Atrophy5
Treatments5
20222
Ranibizumab3
  • Genentech, Inc. announced on May 23, 2005 that a Phase III clinical study of the investigational drug Lucentis (ranibizumab) met its primary efficacy endpoint of maintaining vision in patients with wet AMD. (preventblindness.org)
  • Susvimo (ranibizumab injection) is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (wet) Age-related Macular Degeneration (AMD) who have previously responded to at least two intravitreal injections of a VEGF inhibitor. (rxlist.com)
  • Our Susvimo (ranibizumab injection) for Intravitreal Use Via Susvimo Ocular Implant Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
Macular edema3
  • How are anti VEGF drugs used to treat macular edema? (xshotpix.com)
  • What drugs are used to treat diabetic macular edema? (xshotpix.com)
  • To treat diabetic macular edema, doctors may use drugs that are injected into your eyes to help stop leaking and slow the growth of new blood vessels. (xshotpix.com)
Injections4
  • M.D. Magazine covered a UCLA Stein Eye Institute study by Dr. Michael Ip finding that macular degeneration patients who didn't respond well to injections of the drug Avastin experienced improvement in macular thickness and visual acuity when their medication was switched to Eylea or Regeneron. (ucla.edu)
  • Treatment of wet AMD requires monthly or bimonthly eye injections of drugs that slow or stop the growth of these leaky blood vessels and, in most cases, prevent further vision loss. (thehealthcast.com)
  • In the absence of a prospective, randomized study, there is the potential for substantial bias - enough to change the outcome, results and conclusions - in the selection of the drug and also in the decision for treating and extending injections, since we are all biased into thinking that aflibercept should outlast bevacizumab based on other randomized clinical trials," Bhavsar said. (thehealthcast.com)
  • Patients had the dry form of age-related macular degeneration (AMD) or Stargardt disease and received injections of human embryonic stem-cell (hESC)-derived RPE cells. (medscape.com)
Disc degeneration9
Intervertebral disc1
  • This work provides evidence of association of the PARK2 gene and suggests that methylation of the PARK2 promoter may influence degeneration of the intervertebral disc. (bmj.com)
Eylea3
Therapeutic2
  • Nitroxide small molecule agents are in development as preventative or therapeutic pharmaceutical drugs for age-related macular degeneration (AMD) and cardiovascular disease, which are two major diseases of aging. (frontiersin.org)
  • As a result, DiscGenics is adhering to the rigors of a regulated drug pathway that requires not only proof that the product has a therapeutic effect through clinical evaluation, but also that it meets critical safety standards and is produced consistently from lot to lot through adherence to current good manufacturing practice (cGMP) standards for a cell therapy. (drugdiscoverynews.com)
Epidemiology1
  • DelveInsight's 'Age-related Macular Degeneration (AMD)-Market Insights, Epidemiology, and Market Forecast-2032' report deliver an in-depth understanding of the Age-related Macular Degeneration, historical and forecasted epidemiology as well as the Age-related Macular Degeneration market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan. (delveinsight.com)
Levodopa4
  • The results of an open-label pilot study have found that treating patients with an advanced form of age-related macular degeneration (AMD) using the Parkinson's disease drug, levodopa, stabilized their disease and improved vision. (smpltec.com)
  • But this small, early-stage clinical trial suggests an alternative may be on the horizon: the leading drug used to treat Parkinson's disease, called levodopa. (mylocalpharmacies.com)
  • The trial was an outgrowth of a 2016 study that found Parkinson's patients who took levodopa were less likely to develop macular degeneration. (mylocalpharmacies.com)
  • Maturi also expressed concern about potential side effects of levodopa, especially given the age of the population that is affected by macular degeneration. (mylocalpharmacies.com)
Ophthalmology1
Avastin3
  • There are medications called anti-vascular endothelial growth factor (anti-VEGF) drugs, for example, Avastin (bevacizumab). (xshotpix.com)
  • Even with the monthly eye shots of avastin the macular degeneration is now advancing to the point i'm having trouble reading. (city-data.com)
  • Weekly sounds a bit extreme, the shots consist of a drug called Avastin that is injected into the eye to curb the bleeding of the eyes macular lining, not sure i'd call myself lucky to have to undergo this treatment for the rest of my life. (city-data.com)
Researchers analyzed1
Dysfunction3
Patients20
  • Age-related macular degeneration occurred significantly later in patients with an L-DOPA prescription, 79.4 in all cohorts. (nih.gov)
  • Short version: the same drug which seemed to help macular degeneration (MD) patients, also seems to help those with Parkinson's disease. (smpltec.com)
  • The team of researchers also discovered a striking difference between healthy participants taking NO mind-altering drugs and schizophrenia patients taking antipsychotic drugs. (naturalnews.com)
  • In the study, 71 participants taking no mind-altering drugs were used as control subjects against 33 schizophrenia patients on antipsychotic medications, primarily chlorpromazine hydrochloride -- a dopamine antagonist drug with anti-adrenergic, anti-serotonergic, anti-cholinergic and anti-histaminergic properties. (naturalnews.com)
  • This report describes the protective potential of a peptide derived from the αB crystallin protein using a sodium iodate (NaIO 3 ) induced mouse model of GA. Systemic NaIO 3 challenge causes degeneration of the RPE and neighboring photoreceptors, which have similarities to retinas of GA patients. (nih.gov)
  • A drug long used to treat Parkinson's disease may benefit patients with a severe form of age-related macular degeneration (AMD), a small clinical trial suggests. (mylocalpharmacies.com)
  • In particular, the launch of drugs into the AMD market to treat dAMD is anticipated to be a major factor, as currently, no prescription medications are available for these patients. (medgadget.com)
  • A University of Alberta researcher's past work has led to a new drug being approved for use in the United States to treat patients suffering from Duchenne muscular dystrophy (DMD). (ualberta.ca)
  • The drug is specifically designed to treat about 10 per cent of patients with Duchenne muscular dystrophy who have a specific genetic mutation of the DMD gene," said Yokota, who is also a member of the Neuroscience and Mental Health Institute and the Women and Children's Health Research Institute . (ualberta.ca)
  • Yokota hopes in the future to expand the number of patients the drug could help. (ualberta.ca)
  • Even as efficacy of drug regimens has improved, side effects and length of treatment have continued to be challenges in treating patients with drug-resistant TB [ 3 , 4] . (cdc.gov)
  • Here we show, using large animal models of reperfused MI, that intramyocardial hemorrhage - the most damaging form of reperfusion injury (evident in nearly 40% of reperfused ST-elevation MI patients) - drives delayed infarct healing and is centrally responsible for continuous fatty degeneration of the infarcted myocardium contributing to adverse remodeling of the heart. (nature.com)
  • Wet macular degeneration dx at age 61 and my doc told me I was the youngest by 10 years of any of his patients. (city-data.com)
  • It was not that long ago patients with wet macular degeneration were just sent home and they went blind. (city-data.com)
  • Commenting on the trial in a statement, Dr Carmel Toomes, associate professor at the Leeds Institutes of Molecular Medicine, says: "These results give the many patients out there who suffer from AMD and other retinal degenerations real hope that stem cells replacement therapy may be a reality in the near future. (medscape.com)
  • Paraneoplastic neurologic syndromes include many neurologic disorders including paraneoplastic cerebellar degeneration (PCD) caused by an immune-mediated mechanism other than a metastatic complication in patients with an underlying malignancy. (medscape.com)
  • [ 2 ] Posner found that patients with paraneoplastic cerebellar degeneration can be classified according to the presence or absence of an antibody that reacted with an antigen present in both the tumors and in cerebellar Purkinje neurons obtained from these patients. (medscape.com)
  • Not all patients presenting with paraneoplastic cerebellar degeneration and its clinical features have recognizable antineuronal antibodies. (medscape.com)
  • Introduction: Oral rehabilitation with dental implants becomes limited in patients who make use of sodium bisphosphonate (BF), because this drug inhibits osteoclast activity and thus osteoblastic, fundamental steps to implant osseointegration. (bvsalud.org)
  • Conclusion: The installation of dental implants in patients who make use of BPs presents risks, since this drug can cause OJ. (bvsalud.org)
Treatment19
  • There is no current treatment for spongy degeneration, but research utilising gene therapy to treat the disease is underway. (wikipedia.org)
  • There is currently no treatment available for this kind of age-related macular degeneration, although stopping smoking, eating a healthy diet with plenty of antioxidants and vitamins will help to minimise the damage. (eyehelp.co.uk)
  • Pharmaceutical nitroxide drug candidates for treatment and/or prevention of aging-related and smoking-related diseases are in various different stages of development. (frontiersin.org)
  • According to the report, the global macular degeneration treatment market was valued at US$ 6.1 Bn in 2017. (medgadget.com)
  • The report offers detailed segmentation of the global macular degeneration treatment market based on disease indication, drug class, and distribution channel. (medgadget.com)
  • Drugs such as Apellis' APL-2, Ophthotech's Zimura and Novartis' longer-acting anti-VEGF, brolucizumab are estimated to fuel the global macular degeneration treatment market. (medgadget.com)
  • The research is promising and hopefully signals a potential new treatment for they dry form of macular degeneration and may even hold possibilities for other inflammatory diseases where the protein molecule P2X7 is implicated. (visivite.com)
  • A physician with expertise in drug-resistant TB treatment should be involved in the patient's treatment plan. (cdc.gov)
  • Multidrug-resistant tuberculosis (MDR TB) , caused by MTB that is resistant to at least isoniazid (INH) and rifampin (RIF), has traditionally required longer, more intensive treatment than drug-susceptible disease, including 15-21 months of treatment after culture conversion with 4-7 drugs that are less effective, more toxic, and more costly in treating MDR TB than is a standard first-line regimen in treating drug-susceptible TB [ 1 ]. (cdc.gov)
  • Nutrition plays a key role in macular degeneration treatment. (bodyecology.com)
  • Fish oil supplements are a universally agreed upon macular degeneration treatment. (bodyecology.com)
  • As of now, there's no treatment for dry macular degeneration. (xshotpix.com)
  • The Report also covers current age-related macular degeneration treatment practice, market drivers, market barriers, SWOT analysis, reimbursement, market access, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market. (delveinsight.com)
  • Founded in 2004, Ruxton Pharmaceuticals is an emerging pharmaceutical company that has been formed to discover, develop and market drugs for the treatment of neurodegenerative and other neurological diseases. (webwire.com)
  • Another treatment, called photodynamic therapy (PDT), works on wet macular degeneration sufferers by injecting a drug (Visudyne) into the arm. (lensshopper.com)
  • TB389 trade name] is indicated in combination with other tuberculosis medicines for the treatment of drug- resistant tuberculosis caused by Mycobacterium tuberculosis . (who.int)
  • Objective: This study aimed to review the literature on the influence of bisphosphonates on implant and to evaluate the possible complications resulting from prolonged use, providing subsidies to the dentist to prevent and recognize the patient with osteonecrosis of the jaws Literature review: The BPs are a class of drugs used for the treatment of bone diseases such as osteoporosis, because their mechanism of action inhibits the function of osteoclast. (bvsalud.org)
  • The dentist should know when to indicate or contraindicate the implant placement, and it is important to understand the mechanisms of action of these drugs, having knowledge of their adverse effects and paying attention to prevention and treatment strategies 2, 8, 15, 19, 24, 29 . (bvsalud.org)
  • This drug can stay for a long period within the bone matrix, according to the type of treatment and duration. (bvsalud.org)
Symptoms2
  • Lutein, a type of compound known as a carotenoid, may play a role in preventing or reducing the symptoms of macular degeneration. (medicalnewstoday.com)
  • The onset of symptoms of cerebellar degeneration indicates the presence of an occult malignancy. (medscape.com)
Onset1
Photoreceptors1
Irreversible3
Mice1
  • Mice on ceftriaxone also lived significantly longer than those who got no drug. (webwire.com)
Diseases2
  • Two diseases we discussed could be treated in their beginning stages with these drugs. (proprofs.com)
  • In diseases such as ALS, we hope that this approach might eventually deliver drugs that can be used in combination with other approaches, similar to combinations used in HIV and oncology. (webwire.com)
Lucentis2
Gene2
  • The cause of spongy degeneration of the CNS is the mutation in a gene coding for aspartoacylase (AspA), an enzyme that hydrolyzes N-acetyl aspartic acid (NAA). (wikipedia.org)
  • If we learn more about this process, we may be able to pinpoint ways to intervene with gene or drug therapy to treat certain types of vision loss. (sciencedaily.com)
Significantly3
  • Analysis reveals people taking nucleoside reverse transcriptase inhibitors are significantly less likely to develop dry macular degeneration, a leading cause of age-related vision loss. (drugtargetreview.com)
  • The ones who took metformin had a significantly lower chance - about half - of developing age-related macular degeneration. (invisionmag.com)
  • An additional oral systemic drug that they will take for the rest of their life can significantly affect their quality of life. (mylocalpharmacies.com)
Blood vessels4
  • The laser is used with an intravenous light-sensitive drug to slow down and stop the abnormal blood vessels. (eyehelp.co.uk)
  • These drugs work by targeting the proteins which trigger the abnormal blood vessels which cause AMD to develop. (eyehelp.co.uk)
  • This drug and others like it work by attacking the protein (VEGF) that contributes to the development of the abnormal blood vessels. (lensshopper.com)
  • When the drug enters the retinal blood vessels, the doctor shines a laser into the eye, which activates the drug. (lensshopper.com)
Syndrome1
Pathway3
  • Researchers discovered that the NRTIs effectively treated macular degeneration by blocking a signaling pathway that involves the protein molecule known as P2X7, which is linked to several inflammatory conditions. (visivite.com)
  • BPaL was approved in accordance with the Limited Population Pathway for Antibacterial and Antifungal Drugs (LPAD) for development of drugs targeting infections that lack effective therapies. (cdc.gov)
  • Itraconazole is a cytochrome p-450 inhibitor and may therefore increase or prolong plasma concentrations of other drugs metabolized by this pathway. (drugs.com)
Pathological1
  • Radical-induced oxidative stress and inflammation can be modulated by Tempol (TP)-based nitroxide drugs to prevent or treat vascular, ocular, and other pathological conditions and aging associated disease. (frontiersin.org)
Study9
  • In particular, LLDs and diabetes drugs are candidates worthy of further study. (medicalnewstoday.com)
  • all drugs in the study were associated with similar declines in brain volume. (naturalnews.com)
  • You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. (ehealthme.com)
  • Dosage of drugs is not considered in the study. (ehealthme.com)
  • Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet , Mayo Clinic Proceedings , and Nature . (ehealthme.com)
  • Researchers at the University of Kentucky along with researchers from Cardiff University published the results of a study involving the use of NRTIs ( N ucleotide R everse T ranscriptase I nhibitors) in treating macular degeneration in the journal of Science . (visivite.com)
  • To conclude, the present study provides evidence that ABPS can inhibit the expression of lncRNA GAS5 in chondrocytes to regulate the homeostasis of ECM, which in turn may delay the occurrence of cartilage degeneration during OA. (spandidos-publications.com)
  • Purpose: The aim of this study was to examine whether use of regular aspirin and/or other non-steroidal anti-inflammatory drugs (NSAIDs) is associated with the development of age-related macular degeneration (AMD). (cdc.gov)
  • Genetic variation in targets of lipid-lowering drugs and amyotrophic lateral sclerosis risk: a Mendelian randomization study. (cdc.gov)
Deterioration1
Parkinson's1
VEGF4
  • These are laser photocoagulation (heat laser), photo dynamic therapy and anti-vascular endothelial growth factor (VEGF) drugs. (eyehelp.co.uk)
  • Antiangiogenic drugs prevent the VEGF from binding with the receptors on the surface of the endothelial cells. (preventblindness.org)
  • There are medications called anti-VEGF drugs. (xshotpix.com)
  • The anti-VEGF drugs all work in similar ways to block vessel formation and prevent leakage in the retina. (xshotpix.com)
MedlinePlus1
Metabolism4
  • Erowid.org: Erowid Reference 3224 : 5-Hydroxytptamine Metabolism in the Brain Under the Influence of Psychotropic Drugs. (erowid.org)
  • 5-Hydroxytptamine Metabolism in the Brain Under the Influence of Psychotropic Drugs. (erowid.org)
  • The influence of psychotropic drugs on 5-HT metabolism in the brain is reviewed. (erowid.org)
  • With neuroleptic drugs, the most significant changes in 5-HT metabolism in the brain are produced by Rauwolfia serpentine alkaloids and benzoquinoline derivatives. (erowid.org)
Lipid-lower2
  • The findings show that lipid-lowering drugs and anti-diabetic drugs are linked to lower AMD prevalence. (medicalnewstoday.com)
  • Studies have examined how various drugs, such as lipid-lowering drugs (LLD)s like statins, nonsteroidal anti-inflammatory drugs (NSAIDs) , and antidiabetic drugs , affect the development of AMD. (medicalnewstoday.com)
Neurodegenerative1
  • Spongy degeneration of the central nervous system, also known as Canavan's disease, Van Bogaert-Bertrand type or Aspartoacylase (AspA) deficiency, is a rare autosomal recessive neurodegenerative disorder. (wikipedia.org)
Nerves1
  • Subacute combined degeneration (SCD) is a disorder of the spine, brain, and nerves. (medlineplus.gov)
Efficacy1
  • The human data indicates safety and efficacy for these nitroxide drugs. (frontiersin.org)
Subsequent2
  • Subsequent demyelination possibly contributes to vacant spaces in the white matter or spongy degeneration. (wikipedia.org)
  • But back surgeries often have limited success, and may result in subsequent adjacent level degeneration. (drugdiscoverynews.com)
Therapy3
  • But stopping therapy altogether in wet AMD has to be done carefully, since it is a chronic degenerative disease, and as we age, the degeneration continues. (thehealthcast.com)
  • SALT LAKE CITY- DiscGenics, Inc . announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for DiscGenics' IDCT, an investigational cell therapy. (drugdiscoverynews.com)
  • The expected launch of potential therapy may increase market size in the coming years, assisted by an increase in the diagnosed prevalent population of Age-related Macular Degeneration. (delveinsight.com)
Weakness1
  • This leads to muscular degeneration and weakness. (ualberta.ca)
Vision4
Common1
  • The infantile type is the most common type of spongy degeneration of the CNS. (wikipedia.org)
Injury1
  • Ceftriaxone was neuroprotective in vitro when used in paradigms of ischemic injury [stroke] and motor neuron degeneration, both based in part on glutamate toxicity, writes principal author Jeffrey D. Rothstein, M.D., Ph.D., director of the Robert Packard Center for ALS Research at Johns Hopkins and Professor of Neurology and Neuroscience at Johns Hopkins. (webwire.com)
Found5
  • Spongy degeneration is found to be more prevalent among Ashkenazi Jews, with an incidence of 1/6000 amongst this ethnic group. (wikipedia.org)
  • They found that LLDs and antidiabetic drugs are linked to a lower prevalence of AMD. (medicalnewstoday.com)
  • After analyzing the data, they found that LLDs and antidiabetic drugs were linked to 15% and 22% lower AMD prevalence. (medicalnewstoday.com)
  • Research has found that vitamins A, C and E from your food are an effective way to slow down macular degeneration. (bodyecology.com)
  • Doctors found that zinc, combined with antioxidants, further prevents age related macular degeneration and promotes immune system health. (bodyecology.com)