Antibiotic2023AmpicillinAntibioticsMedicationInteractionsBacteriaCeftriaxoneKanamycinResistanceMedicationsVancomycinInjectionFormularyInhibitorsDropsMoleculePrescribeDiseasesInfectionsResistantCYP3A4DoseBindsStrainsDecreaseCompoundsPrecautionsPreventsAllergicVeterinarianSeverityFormulationCoumadinInteractMechanismsRecommendsPotentIncreasesCommonlyShortagesSideAcidFactorsDogsMetabolismTopicalPharmacist
Antibiotic7
- Chloramphenicol injection should not be used when another antibiotic can treat your infection. (medlineplus.gov)
- Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. (wikipedia.org)
- Chloramphenicol is a broad-spectrum antibiotic that typically stops bacterial growth by stopping the production of proteins. (wikipedia.org)
- In the context of preventing endophthalmitis, a complication of cataract surgery, a 2017 systematic review found moderate evidence that using chloramphenicol eye drops in addition to an antibiotic injection (cefuroxime or penicillin) will likely lower the risk of endophthalmitis, compared to eye drops or antibiotic injections alone. (wikipedia.org)
- We have demonstrated that drug-resistance frequently declines within 480 generations during exposure to an antibiotic-free environment. (elifesciences.org)
- Chloramphenicol is an antibiotic that works by preventing the growth of bacteria. (alliedmarketresearch.com)
- For example, newborns cannot metabolize and eliminate the antibiotic chloramphenicol. (merckmanuals.com)
20231
- 2023. https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/51145/all/chloramphenicol. (unboundmedicine.com)
Ampicillin3
- One example is the ACCoT plasmid (A=ampicillin, C=chloramphenicol, Co=co-trimoxazole, T=tetracycline), which mediates multiple drug resistance in typhoid (also called R factors). (wikipedia.org)
- There are at least 13 antibiotics on the CDC list of drugs the outbreak strains are resistant to, including ampicillin, ciprofloxacin, streptomycin and tetracycline. (foodsafetynews.com)
- 13.0% (18/138) with the most common resistance profile being resistance to ampicillin-chloramphenicol-ciprofloxacin from Salmonella Enteritidis isolates ( n = 5). (who.int)
Antibiotics6
- Chloramphenicol injection is used to treat certain types of serious infections caused by bacteria when other antibiotics cannot be used. (medlineplus.gov)
- Chloramphenicol injection is in a class of medications called antibiotics. (medlineplus.gov)
- Antibiotics such as chloramphenicol injection will not work for colds, flu, or other viral infections. (medlineplus.gov)
- If you stop using chloramphenicol injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. (medlineplus.gov)
- Their products are antibiotics erythromycin salts chloramphenicol and other chemicals. (business-standard.com)
- Ceftazidime belongs to a group of drugs called cephalosporin antibiotics, which work to stop the growth of bacteria in the body. (rxwiki.com)
Medication8
- Overdose of topical medication is not likely to cause a problem except with the corticosteroid as noted in the drug interactions. (wedgewoodpharmacy.com)
- Antiepileptic drugs should be used carefully, with consideration of medication interactions and potential side effects. (medscape.com)
- Our Stalevo (carbidopa, levodopa and entacapone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
- The medication is also available as the brand-name drugs Glucotrol and Glucotrol XL. (medicalnewstoday.com)
- A generic drug is an exact copy of the active drug in a brand-name medication. (medicalnewstoday.com)
- Overview of Adverse Drug Reactions Adverse drug reactions (adverse effects) are any unwanted effects of a drug or medication. (merckmanuals.com)
- any unwanted effects of a drug or medication). (merckmanuals.com)
- Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. (medbroadcast.com)
Interactions5
- This is not a complete list of ceftazidime drug interactions. (rxwiki.com)
- Drug interactions may change how your medications work or increase your risk for serious side effects. (kaiserpermanente.org)
- This document does not contain all possible drug interactions. (kaiserpermanente.org)
- Drug-Disease Interactions The effect a drug has on a person may be different than expected because that drug interacts with Another drug the person is taking (drug-drug interaction) Food, beverages, or supplements the. (merckmanuals.com)
- How mind-body interactions, such as mental attitude, outlook, belief in self, and confidence in health care practitioners, influence adverse drug reactions remains largely unexplored. (merckmanuals.com)
Bacteria5
- Chloramphenicol has a broad spectrum of activity and has been effective in treating ocular infections such as conjunctivitis, blepharitis etc. caused by a number of bacteria including Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli. (wikipedia.org)
- It is easy to select for reduced membrane permeability to chloramphenicol in vitro by serial passage of bacteria, and this is the most common mechanism of low-level chloramphenicol resistance. (wikipedia.org)
- Used for community acquired pneumonia caused by various bacteria including multi-drug resistant pneumococci. (mindmeister.com)
- Chloramphenicol eye drops are used to treat eye infections caused by bacteria (called bacterial conjunctivitis). (alliedmarketresearch.com)
- which drug is very useful for resistant bacteria? (brainscape.com)
Ceftriaxone1
- Currently, a third-generation cephalosporin (ceftriaxone or cefotaxime) is the drug of choice for the treatment of meningococcal meningitis and septicemia. (medscape.com)
Kanamycin1
- chloramphenicol and kanamycin. (bvsalud.org)
Resistance6
- Some strains of E. coli, for example, show spontaneous emergence of chloramphenicol resistance. (wikipedia.org)
- Three mechanisms of resistance to chloramphenicol are known: reduced membrane permeability, mutation of the 50S ribosomal subunit, and elaboration of chloramphenicol acetyltransferase. (wikipedia.org)
- medical citation needed] Chloramphenicol resistance may be carried on a plasmid that also codes for resistance to other drugs. (wikipedia.org)
- and Staphylococcus capitis strains have also developed resistance to chloramphenicol to varying degrees. (wikipedia.org)
- Antimicrobial drug resistance of 344 Shigella spp. (cdc.gov)
- The report also includes a summary on the status of drug resistance for TB, HIV and malaria. (who.int)
Medications6
- tell your doctor and pharmacist if you are allergic to chloramphenicol injection or any other medications. (medlineplus.gov)
- Other medications may also interact with chloramphenicol injection, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. (medlineplus.gov)
- A drug class is a group of medications that work in a similar way. (medicalnewstoday.com)
- Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in lower exposure to these medications. (medscape.com)
- Avoid or substitute another drug for these medications when possible. (medscape.com)
- Hereditary factors make some people more susceptible to the toxic effects of certain drugs (including medications). (merckmanuals.com)
Vancomycin1
- During the last decade chloramphenicol has been re-evaluated as an old agent with potential against systemic infections due to multidrug-resistant gram positive microorganisms (including vancomycin resistant enterococci). (wikipedia.org)
Injection8
- Chloramphenicol injection may cause a decrease in the number of certain types of blood cells in the body. (medlineplus.gov)
- It is best that you receive chloramphenicol injection in the hospital so that you can be closely monitored by your doctor. (medlineplus.gov)
- Talk to your doctor about the risks of receiving chloramphenicol injection. (medlineplus.gov)
- Chloramphenicol injection comes as a liquid to be injected into a vein by a doctor or nurse in a hospital. (medlineplus.gov)
- You should begin to feel better during the first few days of treatment with chloramphenicol injection. (medlineplus.gov)
- Use chloramphenicol injection for as long as your doctor tells you, even if you feel better. (medlineplus.gov)
- In the event of biological warfare, chloramphenicol injection may be used to treat and prevent dangerous illnesses that are deliberately spread such as plague, tularemia, and anthrax of the skin or mouth. (medlineplus.gov)
- Recurrent wound botulism among injection drug users in California. (medscape.com)
Formulary2
- The Optometrists' Formulary data sheets provide prescribing information on all drugs currently available to optometrists, helping you to deal efficiently with patients' eye conditions. (college-optometrists.org)
- Log in to browse, order and prescribe from our compounded drugs formulary. (wedgewoodpharmacy.com)
Inhibitors2
- The main groups include sodium channel blockers, calcium current inhibitors, gamma-aminobutyric acid (GABA) enhancers, glutamate blockers, carbonic anhydrase inhibitors, hormones, and drugs with unknown mechanisms of action (see the image below). (medscape.com)
- The drug-like properties of compounds were evaluated first and then molecular docking using DS v20.1.0.19295 software showed that the compounds behaved as non-nucleoside reverse transcriptase inhibitors (NNRTIs) while interacting at the allosteric site of target HIV-RT protein (PDB:3MEC). (bvsalud.org)
Drops6
- Chloramphenicol drops and ointments are extensively used for treating eye infections. (mindmeister.com)
- This, in turn, is expected to have a significant impact on the global chloramphenicol eye drops market. (alliedmarketresearch.com)
- Increase in prevalence of ophthalmic disorders and increase in geriatric population who are more prone to suffer from these eye disorders are expected to drive the growth of the chloramphenicol eye drops market. (alliedmarketresearch.com)
- Furthermore, easy availability and accessibility of lubricating eye drops and drug discovery & development in eye care products fuel the market growth. (alliedmarketresearch.com)
- In addition, surge in prevalence of dry eye syndrome across the world is expected to propel the market growth of chloramphenicol eye drops market. (alliedmarketresearch.com)
- However, side effects associated with ophthalmic eye drops are expected to hamper the chloramphenicol eye drops market growth. (alliedmarketresearch.com)
Molecule2
- this gene codes for an enzyme called chloramphenicol acetyltransferase, which inactivates chloramphenicol by covalently linking one or two acetyl groups, derived from acetyl-S-coenzyme A, to the hydroxyl groups on the chloramphenicol molecule. (wikipedia.org)
- Prodrugs have better delivery properties that surpass the parent drug molecule [ 1 ]. (ijpsonline.com)
Prescribe1
- If you're pregnant, your doctor may prescribe chloramphenicol instead. (healthline.com)
Diseases1
- OTC drugs enable people to relieve many annoying symptoms and to cure some diseases simply and without the cost of seeing. (merckmanuals.com)
Infections3
- However, these decreases have not been observed among HIV-infected injecting-drug users, suggesting that more emphasis should be placed on providing currently recommended chemoprophylactic agents to all persons who have HIV infection and who meet appropriate criteria for prophylaxis for opportunistic infections. (cdc.gov)
- The surveillance data also indicate that the incidence of some opportunistic infections is not decreasing among either men who have sex with men or injecting-drug users, indicating that preventive strategies need to be developed and applied to a wider spectrum of opportunistic infections. (cdc.gov)
- Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
Resistant3
- The original indication of chloramphenicol was in the treatment of typhoid, but the presence of multiple drug-resistant Salmonella typhi has meant it is seldom used for this indication except when the organism is known to be sensitive. (wikipedia.org)
- medical citation needed] As of 2014 some Enterococcus faecium and Pseudomonas aeruginosa strains are resistant to chloramphenicol. (wikipedia.org)
- B. cerus, B. subtilis, S. aureus, E. coli and P. aeruginosa and drug resistant strain (DRS) of E. coli. (bvsalud.org)
CYP3A45
- chloramphenicol will increase the level or effect of alfuzosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- chloramphenicol will increase the level or effect of eletriptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- chloramphenicol will increase the level or effect of eplerenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- chloramphenicol increases levels of lurasidone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- chloramphenicol will increase the level or effect of doxorubicin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
Dose1
- If use is unavoidable, closely monitor for adverse reactions and consider dose reduction of BCRP substrate drug (refer BCRP substrate prescribing information). (medscape.com)
Binds1
- which drug binds to divalent cations, and prevent absorption of nutrients? (brainscape.com)
Strains1
- The results clearly indicated the possibility of these compounds as active ingredients of drug regimen used against MDR strains. (bvsalud.org)
Decrease2
- You may experience this decrease in blood cells whether you are being treated with chloramphenicol for a long time or a short time. (medlineplus.gov)
- The removal percentage of CHZ drug increase from 55.45 to 89.8%, and adsorption capacity decrease from 65.5 to 110 mg g -1 on to hydrogel nanocomposite. (ac.ir)
Compounds3
- Wedgewood Pharmacy compounds Chloramphenicol/Prednisolone/ Tetracaine/Squalane 4.2mg/1.7mg/4.5mg/0.21ml/ml Ointment in response to the discontinuation of Liquachlor by the manufacturer. (wedgewoodpharmacy.com)
- TOPKAT (Toxicity Prediction by Komputer Assisted Technology) results confirmed that the compounds were found to be less toxic than the reference drugs. (bvsalud.org)
- Thus, the results positively endorsed the compounds as potent antibacterial and antifungal agents which could be developed as possible drug regimens. (bvsalud.org)
Precautions1
- See the "Drug Precautions" section. (rxwiki.com)
Prevents2
- The acetylation prevents chloramphenicol from binding to the ribosome. (wikipedia.org)
- A drug that prevents sensations such as pain. (petplace.com)
Allergic2
- Chloramphenicol/Prednisolone/Tetracaine/Squalane 4.2mg/1.7mg/4.5mg/0.21ml/ml Ointment is used in the treatment of bacterial or allergic otitis. (wedgewoodpharmacy.com)
- A very serious allergic reaction to this drug is rare. (kaiserpermanente.org)
Veterinarian3
- We can let your veterinarian know that you are interested in our compounded Chloramphenicol / Prednisolone / Tetracaine / Squalane. (wedgewoodpharmacy.com)
- Ketamine is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. (petplace.com)
- Consult with your veterinarian to determine if other drugs your pet is receiving could interact with ketamine. (petplace.com)
Severity1
- The number and severity of adverse drug reactions increase disproportionately as the number of drugs taken increases. (merckmanuals.com)
Formulation1
- The prodrug approach using various carriers has evolved as a significant tool in surmounting different obstacles in relation to drug formulation and targeting. (ijpsonline.com)
Coumadin1
- Be sure to mention any of the following: chloramphenicol, and warfarin (Coumadin, Jantoven). (epnet.com)
Interact1
- What Drugs, Substances, or Supplements Interact with Stalevo? (rxlist.com)
Mechanisms1
- It is important to understand the mechanisms of action and the pharmacokinetics of antiepileptic drugs (AEDs) so that these agents can be used effectively in clinical practice, especially in multidrug regimens (see the image below). (medscape.com)
Recommends1
- medical citation needed] In low-income countries, the WHO no longer recommends only chloramphenicol as first-line to treat meningitis, but recognises it may be used with caution if there are no available alternatives. (wikipedia.org)
Potent2
- Chloramphenicol (CAP) is a potent and effective mechanism-based inactivator of the major phenobarbital (PB)-inducible isozyme of dog liver cytochrome P-450 (PBD-2) in vitro. (aspetjournals.org)
- Prophylactic regimens against opportunistic pathogens and more potent antiretroviral drugs appear to be important factors influencing this decline in incidence. (cdc.gov)
Increases1
- The use of alcohol, which is also a drug, also increases the risk. (merckmanuals.com)
Commonly2
- Moreover, commonly used drugs such as hydroxychloroquine have witnessed a dramatic surge in demand for the management of COVID-19. (alliedmarketresearch.com)
- It contains two drugs commonly used to lower blood sugar, glipizide (Glucotrol) and metformin (Glucophage). (family-health-information.com)
Shortages2
- Find out the latest information on drug shortages and discontinuations across the UK. (college-optometrists.org)
- A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. (fda.gov)
Side5
- The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. (medicalnewstoday.com)
- This side effect was reported after the drug was released on the market. (medicalnewstoday.com)
- See below for more detail on certain side effects this drug may cause. (medicalnewstoday.com)
- Did you experience many side effects while taking this drug? (rxwiki.com)
- Doing so can release all of the drug at once, increasing the risk of side effects. (kaiserpermanente.org)
Acid2
- Preparation two hydrogel (SA-g-P(Ac-co-AM) hydrogel and the second hydrogel after loading CNT/ZnO onto hydrogel and these new hydrogel surfaces were prepared from two monomers (acryl acid, acrylamide) to remove Chloramphenicol CHZ drug .The physical characterizations of new super adsorbent hydrogel nanocomposite were performed using XRD, FTIR, TGA, EDX and TEM. (ac.ir)
- Stalevo, a combination drug consisting of levodopa (aromatic amino acid), carbidopa (aromatic amino acid decarboxylation inhibitor), and entacapone (catechol-O-methyltransferase (COMT) inhibitor) is indicated for the treatment of Parkinson's disease. (nih.gov)
Factors1
- The value of this ratio is limited by other factors that can affect BUN independently, such as various drugs. (medscape.com)
Dogs1
- In dogs, ketamine is often combined with other drugs. (petplace.com)
Metabolism3
- Thank you for sharing this Drug Metabolism & Disposition article. (aspetjournals.org)
- Message Body (Your Name) thought you would be interested in this article in Drug Metabolism & Disposition. (aspetjournals.org)
- For example, differences in certain genes can affect metabolism of drugs in the liver, allowing drug levels to rise and increase the chances of an adverse drug reaction. (merckmanuals.com)
Topical1
- what drug is a topical that usually is a combo with Bacitracin? (brainscape.com)
Pharmacist1
- Asking a doctor or pharmacist to periodically review all the drugs a person is taking and to make appropriate adjustments can reduce the risk of an adverse drug reaction. (merckmanuals.com)