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  • antibiotics
  • Analysis of pediatric drug utilization trends for the top 12 therapeutic areas in 2010 compared with 2002 showed decreases in systemic antibiotics (-14%), allergies (-61%), pain (-14%), depression (-5%), and cough/cold without expectorant (-42%) prescriptions, whereas asthma (14%), attention-deficit/hyperactivity disorder (46%), and contraceptive (93%) prescriptions increased. (aappublications.org)
  • As bacterial resistance has grown due to inappropriate use of antibiotics we sought to evaluate the current utilization of cephalosporins in inpatient departments, in terms of rational usage towards indication, dosage, dosing regimen, and dosage adjustments in comorbid conditions (renal and hepatic impairments). (alliedacademies.org)
  • Retrospective
  • The second phase is a retrospective DUR and involves ongoing and periodic examinations of claims data to identify patterns of fraud, abuse, underutilization, drug-drug interaction, or medically unnecessary care, implementing corrective actions when needed. (ahdbonline.com)
  • renal
  • This program offers assistance in individual dosing of drugs for patients with impaired renal function. (dosing.de)
  • the Q 0 value (extra-renally excreted fraction in case of normal renal function) of the drug is (dosing.de)
  • Given that, on the one hand, the individual variability of pharmacokinetic parameters are large and, on the other hand, there is an increased risk of adverse drug reactions in patients with renal impairment, close monitoring of therapy is necessary, despite adjustments of the dosing regimen. (dosing.de)
  • Inappropriateness of drug therapy was found in phase I (before intervention) and appropriateness in terms of rational use for indication, dose, dosing interval, renal dosage adjustment was improved in phase II this may be due to the implementation of the DUE guidelines through interventions obtained during phase. (alliedacademies.org)
  • adverse drug reac
  • Through dose adjustment, excessive drug accumulation, and thereby the risk of adverse drug reactions and unnecessary costs, may be reduced. (dosing.de)
  • For proper and impartial monitoring of rational drug use, drug utilization reviews (DUR) are used to identify common problems such as inappropriate product selection, incorrect dosing, avoidable adverse drug reactions, and errors in drug dispensing and administration (see Managing Drug Supply 3: Chapter 30 , PDF). (msh.org)
  • Several of these drugs are classified as potentially inappropriate medication (PIM) for elderly people due to their increased risk for causing adverse drug reactions (ADR). (egms.de)
  • Cohort
  • Dtsch Arztebl Int we aimed to analyze PIM utilisation in two cohorts of elderly outpatients, namely the getABI-cohort [Diehm et al. (egms.de)
  • DDI most often involved selective beta-blockers (8/29), which were the most frequently prescribed drugs in the cohort (6.3% of all prescriptions, 93/1,471), resulting in a relative DDI frequency of 8.6% (8/93). (egms.de)
  • Pharmacy
  • Information on drug use was obtained from the IADB.nl database, which contains pharmacy-dispensing data from community pharmacies in the Netherlands. (springer.com)
  • contraindications
  • The first step of identifying drug-disease interaction risks ('Gegenanzeigen') was performed by an electronic database tool which connects each drug (ATC-code) with contraindications (according the summary of medicinal product characteristics as digested in Rote Liste coded as three-digit ICD-10). (egms.de)
  • unnecessary
  • Appropriate actions include discontinuing unnecessary prescriptions, reducing quantities of prescribed medications, switching to safer drug therapies, or adding a therapy recommended in published (evidence-based) guidelines from an expert panel. (ahdbonline.com)
  • indicators
  • Successful treatment of tuberculosis (TB) is one of the key indicators of a TB Control Program's performance and essential to containing the emergence of anti-TB drug resistance. (msh.org)
  • However, international guidelines and national regulations for the diagnosis and treatment of MDR-TB seldom provide unbiased sources of information on monitoring drug use, side effects, or indicators to assess the quality of prescribing according to the regulations. (msh.org)
  • From the literature, drug use monitoring criteria and indicators were selected for each anti-MDR TB drug, and then data collection forms were developed. (msh.org)
  • seldom
  • Food consumers seldom hear about the drugs oestradiol-17, zeranol, trenbolone acetate and melengestrol acetate and the names are certainly not on meat labels. (connexions.org)
  • Tool
  • All potential drug-disease interactions (DDI) identified by this tool were reviewed by two independent investigators (both pharmacists), and discrepancies were reviewed by rater C (experienced general internist). (egms.de)
  • individuals
  • The geographical variation in the use of anti-inflammatory drugs among individuals with diagnosed asthma may be related to variations in asthma severity, as well as differences in treatment practices between countries. (ersjournals.com)
  • frequently
  • Co-amoxiclav was the drug which most frequently ranked first (28 times). (eurekaselect.com)
  • The number of drugs constituting the DU75% by substance ranged from 7-15 (median 12) and 8- 19 (median 15) by RoA which identified oral amoxicillin most frequently ranking first (17 times). (eurekaselect.com)