Drug interactions meperidine. Medical search. Frequent questions

SAMe is contra-indicated with anti-depressant medication, dextromethorphan, and meperidine (Demerol). (pureprescriptions.com)
The synthetic opioid meperidine hydrochloride (meperidine HCL), also known as pethidine or the brand name product line Demerol , is prescribed to treat moderate to severe pain and, less commonly, chronic pain. (recoveryohio.org)
Finally, concomitant use of Demerol with drugs that increase serotonin levels, such as methylene blue, certain antidepressants, MDMA, and St. John's Wort, should be handled with caution as this can cause a potentially serious condition known as serotonin syndrome. (recoveryohio.org)
DescriptionPethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class. (chemicalspharmstore.com)
Demerol (meperidine) is an opioid pain medication. (chemicalspharmstore.com)
You should not use Demerol if you are allergic to meperidine, or if you have severe asthma or breathing problems. (chemicalspharmstore.com)
Of note is the avoidance of meperidine (Demerol) in patients with CKD or end-stage renal disease (ESRD) because the active metabolite (normeperidine) can accumulate and cause seizures. (medscape.com)

Types of medications that you might be given for a colonoscopy include diazepam, midazolam, fentanyl, propofol, meperidine and diphenhydramine. (horizononcologycenter.com)
Meperidine is a relatively weak opioid analgesic when compared to morphine (which is 7-10 times more potent than meperidine by weight) or even stronger opioids like fentanyl. (recoveryohio.org)

Morphine is an opioid analgesic similar to meperidine but is considered safe and does not induce serotonin syndrome in patients taking MAOIs. (thepassmachine.com)

Severe adverse interaction between pethidine and selegiline. (webmd.com)
CYP2B6 has been demonstrated to play a role in the metabolism of 2%-10% of clinically used drugs including widely used antineoplastic agents cyclophosphamide and ifosfamide, anesthetics propofol and ketamine, synthetic opioids pethidine and methadone, and the antiretrovirals nevirapine and efavirenz, among others. (drugbank.com)

Meperidine is a synthetic opioid agonist belonging to the phenylpiperidine class. (ispub.com)

17.Sovner R, Wolfe J. Interaction between dextromethorphan and monoamine oxidase inhibitor therapy with isocarboxazid. (webmd.com)

The precise mechanism of action (i.e., exactly how these drugs work) is not known fully but it is believed that they act by increasing the activity of the neurotransmitter serotonin in the brain. (marvistavet.com)
In a patient who is taking MAOIs, meperidine should be avoided as it can result in serotonin syndrome which occurs due to an over-activation of peripheral and central serotonin receptors. (thepassmachine.com)
Meperidine acts by inhibiting serotonin uptake, increasing serotonin release and activating serotonin receptors, and MAOIs act by decreasing serotonin metabolism, all of these actions will eventually lead to an increase in the serotonin levels and result in serotonin syndrome. (thepassmachine.com)
Other opioids are also serotonergic and can be associated with serotonin syndrome due to drug interactions with MAOIs, SSRIs, SNRIs or triptans. (thepassmachine.com)
Some medicines can interact with meperidine and cause a serious condition called serotonin syndrome. (chemicalspharmstore.com)

In meperidine group most of the patients had a VAS score higher than seven in the second hour after the operation and had extra analgesics. (ispub.com)
J Am Dent Assoc 1999 Mar;130(3):397-407 - Adverse drug interactions in dental practice: interactions associated with analgesics, Part III in a series. (personalhealthzone.com)

Potentially life-threatening drug-drug interactions (see Contraindications). (oncologynurseadvisor.com)

Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. (medscape.com)
Over 100 concomitant medications were used, with no documented drug-drug interactions. (cdc.gov)

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. (medbroadcast.com)
They can help determine if the medication is right for you and advise on potential interactions or side effects. (healthpluscity.com)
Examples of drugs and supplements to stop taking are fiber supplements, anti-diarrheal medication, iron supplements and medications with iron. (horizononcologycenter.com)
Our Vantrela ER (hydrocodone bitartrate) Extended-Release Tablets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
Never share this medicine with another person, especially someone with a history of drug abuse or addiction.MISUSE OF NARCOTIC PAIN MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. (chemicalspharmstore.com)
Therefore, the aim of this study was to review the literature and discuss the use of systemic medication in Endodontics, aiming to guide the use of these drugs only when really necessary. (bvsalud.org)

Actually, serious reactions have only been observed between L-Deprenyl (a monoamine oxidase inhibitor) and meperidine (an opiate), but, to be safe, the warning has been extended to all opiate/monoamine oxidase inhibitor combinations. (vin.com)
MAO inhibitor and meperidine are both serotonergic drugs and should not be used concurrently. (thepassmachine.com)
If an MAO Inhibitor or this drug is stopped, wait 2 weeks before starting the other drug. (healthanddiets.com)

Monoamine oxidase inhibitors have very few veterinary uses where this is likely to be an issue but there are two situations where this drug interaction might be relevant. (marvistavet.com)
Opioids should not be combined with alcohol, and meperidine must be avoided in the patient who has taken monoamine oxidase inhibitors in the previous 14 days. (personalhealthzone.com)
People taking certain medications, such as monoamine oxidase inhibitors (MAOIs) or other drugs that affect the central nervous system. (healthpluscity.com)

Using alcohol or tobacco with certain medicines may also cause interactions to occur. (mayoclinic.org)
Also, talk to your doctor if you have or had an addiction to alcohol or any other drug. (healthpluscity.com)
Dangerous side effects or death can occur when alcohol is combined with meperidine. (chemicalspharmstore.com)
Also tell them if you smoke, drink alcohol, or use illegal drugs. (clevelandclinic.org)

Effective analgesia is important after caesarean section but ın the literature there are no studies on the clinical efficiency of paracetamol (perfalgan) compared to meperidine in the postoperative analgesia after caesarean section. (ispub.com)
In this study, we compare the quality of analgesia and side effects of paracetamol versus meperidine for postoperative analgesia after elective caesarean section. (ispub.com)
Our resuts indicate that i.v. paracetamol has better analgesic potency than i.v. meperidine for postoperative analgesia after caesarean section. (ispub.com)
In our instutition it is general practice to administer meperidine for post-caesarean section analgesia. (ispub.com)
The purpose of this randomised, double blinded study was to compare the quality of analgesia and side effects of intravenous paracetamol 1 g versus intravenous meperidine 100 mg for postoperative analgesia after elective caesarean section. (ispub.com)

Despite its inability to produce recreational euphoria, diphenoxylate hydrochloride is actually a member of the opiate class of drugs. (vin.com)
Dangerous potentiation of meperidine hydrochloride by pargyline hydrochloride. (webmd.com)

DIPRIVAN is an intravenous general anesthetic and sedation drug for use in the induction and maintenance of anesthesia or sedation. (guidelinecentral.com)

In patients taking levodopa, with or without other PD drugs (e.g., dopamine agonist, amantadine, anticholinergics), the recommended initial dose of rasagiline tablets are 0.5 mg once daily. (nih.gov)

Naltrexone is used to help narcotic dependents who have stopped taking narcotics to stay drug-free. (mayoclinic.org)

Never administer any drug without your veterinarian's input. (vin.com)

Since 1994 there has been a rapid expansion of information about the specificity of hepatic microsomal enzymes of the cytochrome P450 family for the metabolism of different drugs. (liposuction.com)
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. (drugbank.com)

In earlier times, the benzodiazepine family of drugs (of which Valium ® is a member) were the predominant anxiety medications but their use was complicated by sedative side effects and chemical dependence. (marvistavet.com)
Routinely used medications have many potential interactions with drugs used during surgery, but few situations prohibit concurrent administration. (medscape.com)
Kluger et al showed that 44% of surgical patients took medications prior to surgery, with an average of 2.1 drugs per patient. (medscape.com)
Almost 50% of the drugs were omitted on the day of surgery, while on the first day after the operation, 33% of the medications were withheld. (medscape.com)
Review all medications to assess potential drug-drug interactions and determine whether dose adjustment, interruption, and/or additional monitoring is required. (oncologynurseadvisor.com)
According to one survey of students who abuse stimulant medications, as many as 93.5% of the students reported that they abused these drugs in order to increase their ability to study for prolonged periods of time [ 1 ]. (selfhacked.com)
NHAMCS provide an important tool for therapy, with pain relief drugs accounting for almost 30 percent of the medications tracking ambulatory care utilization. (cdc.gov)

The patients were randomly allocated to receive i.v. meperidine 100 mg (n=25) and i.v. paracetamol 1 g (n=25). (ispub.com)
Pooled analyses of short-term (4 to 16 weeks) placebo-controlled trials of 9 antidepressant drugs (SSRIs and others) in children and adolescents with MDD, obsessive compulsive disorder (OCD), or other psychiatric disorders (a total of 24 trials involving over 4400 patients) have revealed a greater risk of adverse events representing suicidality during the first few months of treatment in those receiving antidepressants. (marplan.com)
Additionally, the drug can cause unsteadiness and impairment that can make it unsafe to get up, operate machinery, or drive, especially in elderly patients. (recoveryohio.org)
Ibuprofen, acetaminophen, and celecoxib are all non-steroidal anti-inflammatory drugs that can be safely prescribed to patients taking MAOIs. (thepassmachine.com)
1] In addition, drugs normally excreted by the kidney can accumulate to toxic levels in patients with chronic kidney disease (CKD). (medscape.com)
Therefore, adjusting dosages or avoiding such drugs, including iodinated contrast in high-risk patients, is a key management principle in patients with CKD. (medscape.com)
The administration of general anesthesia may induce a reduction in renal blood flow in up to 50% of patients, resulting in the impaired excretion of nephrotoxic drugs. (medscape.com)
Elderly patients may be more sensitive to the effects of this drug. (healthanddiets.com)
Significant inter-individual variability in the expression and function of the human CYP2B6 gene exists and can result in altered clinical outcomes in patients receiving treatment with CYP2B6-substrate drugs. (drugbank.com)

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. (mayoclinic.org)
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. (mayoclinic.org)
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. (mayoclinic.org)
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. (clevelandclinic.org)

Verapamil was used as a standard drug that has L-Type calcium channel binding activity. (bvsalud.org)

Meperidine is also known to interact with certain drugs that increase or decrease the rate at which meperidine is removed from the body, including certain antifungals, antibiotics like linezolid, cimetidine, ritonavir, phenytoin and other drugs used to treat seizures, and others. (recoveryohio.org)
What Drugs, Substances, or Supplements Interact with Vantrela ER? (rxlist.com)

When the inhibitory effects of MAOIs are amplified by overdose, drug-drug interactions, or drug-food interactions, the resulting increase of active monoamines is directly responsible for the manifestations of MAOI toxicity. (medscape.com)
Interaction between MAOIs and opioids: pharmacologic and clinical considerations. (webmd.com)

You should not take NSAIDs if you have experienced asthma, hives, or allergic-type reactions after taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). (personalhealthzone.com)
All nonsteroidal anti-inflammatory drugs, including coxibs, can worsen arterial hypertension and heart failure. (personalhealthzone.com)
Mefenamic acid is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). (pharmasynth.in)

Ann Pharmacother 1995 Dec;29(12):1274-83 - Adverse interactions between warfarin and nonsteroidal antiinflammatory drugs: mechanisms, clinical significance, and avoidance. (personalhealthzone.com)

However, meperidine should always be used as prescribed due to its potential for side effects , adverse reactions, hazardous drug interactions, and its high risk of addiction, physical dependence, and drug abuse. (recoveryohio.org)

Did you experience many side effects while taking this drug? (rxwiki.com)
Serious side effects or death can occur if you use drugs on your pet without your veterinarian's advice. (vin.com)
With its potential to provide quick relief, it's essential to understand the right dosage, safety precautions, and side effects of this drug. (healthpluscity.com)

Drugs that decrease renal function could decrease clearance. (cdc.gov)

In other series of experiments, we studied drug interaction(s) among Pitavastatin, Lovastatin, and amlodipine. (bvsalud.org)

11.Jounela AJ, Kivimaki T. Possible sensitivity to meperidine in phenylketonuria. (webmd.com)
however, some cases in which the patient exhibits mild pain sensitivity, these drugs are required. (bvsalud.org)

Various clinical studies show that paracetamol is an effective analgesic drug in the postoperative pain ( 11 ). (ispub.com)
Mefenemic acid is a non-steroidal anti inflammatory drug that provides relief from the pain associated with the spasms. (pharmasynth.in)
A definite association implies a temporal relationship of drug administration to abdominal pain and hyperamylasemia or to a positive response to rechallenge. (pocketdrugguide.com)
In the meperidine (MPD) and metyrosine + meperidine (MMPD) groups, paw pain thresholds were measured before and after the treatment between the first and sixth hours (one hour apart). (bvsalud.org)
Although endodontic treatment should be view from a surgical perspective, because local therapy must be firstly instituted, many clinical situations require the use of systemic drugs to act on problems coming from the treatment sequence, such as: inflammatory reaction, pain, and infection that provide more comfort and safety to patient 5 . (bvsalud.org)

This practice has resulted in death with the misuse of meperidine and similar prescription drugs. (chemicalspharmstore.com)

Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. (webmd.com)

Obtain advice on selecting alternative treatments from clinical or drug information pharmacists. (medscape.com)
In this review, we will provide an overview of the key players in CYP2B6 expression and function and highlight recent advances made in assessing clinical ramifications of important CYP2B6-mediated drug-drug interactions. (drugbank.com)
Depending on the clinical signs and symptoms and on the pharmacological effect desired, the professional can choose among a variety of drugs 24 . (bvsalud.org)

See "Drug Precautions" section. (rxwiki.com)

A dangerous drug interaction could occur. (chemicalspharmstore.com)

Never crush or break a tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. (chemicalspharmstore.com)

MAO Inhibitors (see above) and this drug should not be taken together. (healthanddiets.com)

Easily compare up to 40 drugs with our drug interaction checker. (drugbank.com)

Background and Objectives: The purpose of the study was to investigate the role of adrenaline (ADR), noradrenaline (NDR), and cortisol in the pathogenesis of the analgesic potency, duration, and epilepsy-like toxic effect of meperidine. (bvsalud.org)

Antihistamines and decongestants may be found in many nonprescription drugs for cough and cold. (healthanddiets.com)

Drug accumulates when dosed three times a day, reaching steady-state within 3 to 4 days at plasma concentrations about four-fold higher than after a single dose. (nih.gov)
Switching to an alternative formulation of the same drug may involve a change in dose due to differing bioavailability of the active drug. (medscape.com)
Meperidine can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. (chemicalspharmstore.com)
Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. (healthanddiets.com)

Never share this medicine with another person, especially someone with a history of drug abuse or addiction. (chemicalspharmstore.com)
Both Adderall and Vyvanse are classified as Schedule II drugs by the FDA, meaning they pose a high risk of abuse that may lead to physical and/or psychological dependence. (selfhacked.com)

Meperidine can pass into breast milk and may harm a nursing baby. (chemicalspharmstore.com)
It is not known whether this drug is excreted into breast milk. (healthanddiets.com)

In both the popular press and the scientific literature, linezolid has been called a "reserve antibiotic"-one that should be used sparingly so that it will remain effective as a drug of last resort against potentially intractable infections. (wikipedia.org)

Loperamide is a similar drug and may be preferable for dogs as it is believed to have a faster onset of action and lasts longer. (vin.com)

As will become obvious, there are many areas in which basic knowledge about the mechanisms of action of psychoactive drugs does not exist. (druglibrary.net)
We have written this post for informational purposes only, and our goal is solely to inform people about the science behind these drugs' effects, mechanisms, and current approved medical uses. (selfhacked.com)

Fexmid belongs to a class of drugs called muscle relaxants, which help by preventing muscle spasms without affecting overall muscle control and function. (rxwiki.com)

I entered the list of drugs I've taken over the past few months, and it came up with this list of possible interactions. (yak.net)
However, there were about a dozen possible interactions between just the drugs I've taken. (yak.net)
This list may not describe all possible interactions. (clevelandclinic.org)

Dicyclomine is an anti-cholinergic drug that relieves smooth muscle spasm of the gastrointestinal tract, urinary tract and also of the pelvic region that marks its usefulness in treating IBS, anal spasms and moderate to severe spasmodic dysmenorrheal in women and adolescent teens. (pharmasynth.in)

Some authors have recommended that combinations of cheaper or more cost-effective drugs (such as co-trimoxazole with rifampicin or clindamycin) be tried before linezolid in the treatment of SSTIs when susceptibility of the causative organism allows it. (wikipedia.org)
Drug Saf 1998 Nov;19(5):389-410 - Treatment of inflammatory rheumatic disorders in pregnancy: what are the safest treatment options? (personalhealthzone.com)
For the epilepsy experiment, caffeine, caffeine + meperidine, and caffeine + meperidine + metyrapone groups were created, and the treatment was applied for 1 day or 7 days. (bvsalud.org)
In the caffeine (150 mg/kg) + meperidine group, 1-day treatment did not cause epileptic seizures, while seizures were observed and cortisol levels increased in the group in which treatment continued for 7 days. (bvsalud.org)
According to Leonardo and Leal (1998) 10 , the cornerstone of endodontic treatment auxiliary therapy is the correct diagnosis of the pathology itself, from which and based on pharmacological knowledge, one can use the drugs available to treat the patient. (bvsalud.org)

Anatomy1

Organisms1

Diseases2

Chemicals and Drugs28

Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Phenomena and Processes8

Information Science1

Demerol7

Fentanyl2

Morphine1

Pethidine2

Synthetic opioid1

Dextromethorphan1

Serotonin5

Analgesics2

CONTRAINDICATIONS1

Concomitant2

Medication6

Inhibitor3

Monoamine3

Alcohol4

Analgesia5

Hydrochloride2

Sedation1

Levodopa1

Narcotics1

Administer1

Metabolism2

Medications7

Patients9

Medicines4

Verapamil1

Interact2

MAOIs2

Nonsteroidal anti-3

Avoidance1

Adverse reactions1

Side effects3

Renal1

Amlodipine1

Sensitivity2

Pain5

MISUSE1

Healthcare professional1

Clinical3

Precautions1

Dangerous1

Tablet1

Inhibitors1

Checker1

Potency1

Antihistamines1

Dose4

Abuse2

Breast milk2

Potentially1

Similar1

Mechanisms2

Muscle relaxants1

Possible interactions3

Severe1

Treatment5