- Poly(lactic-co-glycolic acid) drug loaded nanoparticles are applied successfully to increase the distribution and bioavailability of hydrophobic drug molecules, although the generally low drug content implies a limitation. (elsevier.com)
- The treatment of nanoencapsulation however, as a partitioning process involving poly(lactic-co-glycolic acid) and aqueous phase led to a relationship between the drug content of the nanoparticles and the characteristic properties of the drug molecule. (elsevier.com)
- The above approach opens the way for more reasonable design of nanoparticle drug carrier in addition to the possible explanation for the drug content achievable for a given compound. (elsevier.com)
- According to that both the high hydrophobicity and high aqueous solubility of the drug favour the efficacy of its encapsulation. (elsevier.com)
- Poly(lactic-co-glycolic acid) nanoparticles were prepared by nanoprecipitation to encapsulate model drugs, a series of alkyl-hydroxy-benzoate (parabens) from methyl-to octyl with increasing hydrophobicity to address the influence of drug property on the encapsulation. (elsevier.com)
- Tóth, T & Kiss, E 2019, ' A method for the prediction of drug content of poly(lactic-co-glycolic)acid drug carrier nanoparticles obtained by nanoprecipitation ', Journal of Drug Delivery Science and Technology , vol. 50, pp. 42-47. (elsevier.com)
- The drug content and encapsulation efficiency were found to be substantially different for the various parabens. (elsevier.com)
- Lipid-polymer hybrid nanoparticles of Norfloxacin showed the %cumulative drug release of 89.72% in 24 h. (pharma-excipients.ch)
- These results illustrated high potential of lipid-polymer hybrid nanoparticles Norfloxacin for usage as a topical antibiotic drug carriers. (pharma-excipients.ch)
