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  • BIOLOGY
  • The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans. (osti.gov)
  • larval
  • A method for culturing blastoderm cells of Drosophila in vivo has been developed that allows these cells to differentiate into larval or adult structures. (pnas.org)
  • proteins
  • Translated from the three mammalian homologs of drosophila-per, one of three PER proteins (PER1, PER2, and PER3) dimerizes via its PAS domain with one of two cryptochrome proteins (CRY1 and CRY2) to form a negative element of the clock. (wikipedia.org)
  • induce
  • Thermal fluctuations during development in Drosophila melanogaster lead to detrimental cold and beneficial heat acclimation responses, while thermal fluctuations induce little acclimation response during adult exposure. (biologists.org)
  • experimental
  • Drosophila became one of the first, and for some time the most widely used, model organisms, and Eric Kandel wrote that Morgan's discoveries "helped transform biology into an experimental science. (wikipedia.org)
  • females
  • Apger-McGlaughon J, Wolfner MF (2013) Post-mating change in excretion by mated Drosophila melanogaster females is a long-term response that depends on sex peptide and sperm. (springer.com)
  • Avila FW, Wolfner MF (2009) Acp36DE is required for uterine conformational changes in mated Drosophila females. (springer.com)
  • Avila FW, Ravi Ram K, Bloch Qazi MC, Wolfner MF (2010) Sex peptide is required for the efficient release of stored sperm in mated Drosophila females. (springer.com)
  • Avila FW, Mattei AL, Wolfner MF (2015b) Sex peptide receptor is required for the release of stored sperm by mated Drosophila melanogaster females. (springer.com)
  • behavioral
  • P450s are also involved in behavioral phenotypes in D. melanogaster , with Cyp6a20 associated with aggressive behavior in males ( 25 , 26 ) and Cyp4d21 necessary for efficient male mating ( 27 ). (pnas.org)
  • model
  • Here, we review the metabolism of TAG in the Drosophila model system. (genetics.org)
  • Synphilin-1 alters metabolic homeostasis in a novel Drosophila obesity model. (nih.gov)
  • Reduced muscle power output and progressive myofibrillar defects in a Drosophila model of inclusion body myopathy 3 arise from the decreased rate of weak to strong actin-binding transition of myosin. (biologists.org)
  • D. melanogaster remains one of the most widely used eukaryotic model organisms. (wikipedia.org)
  • males
  • Species-specific cuticular hydrocarbons displayed on female Drosophila as they mature are sensed by males and act as pheromones to stimulate mating by conspecific males and inhibit heterospecific mating. (springer.com)