• One species of Drosophila in particular, D. melanogaster, has been heavily used in research in genetics and is a common model organism in developmental biology. (wikipedia.org)
  • The terms "fruit fly" and "Drosophila" are often used synonymously with D. melanogaster in modern biological literature. (wikipedia.org)
  • citation needed] Several Drosophila species, including Drosophila melanogaster, D. immigrans, and D. simulans, are closely associated with humans, and are often referred to as domestic species. (wikipedia.org)
  • Drosophila simulans is a species of fly closely related to D. melanogaster, belonging to the same melanogaster species subgroup. (wikipedia.org)
  • We present measurements of genetic variation in preadult viability in a laboratory-adapted population of Drosophila melanogaster, made at four different densities. (bioone.org)
  • Using whole-genome quantitative gene expression as a model, here we study how the genetic architecture of regulatory variation in gene expression changed in a population of fully sequenced inbred Drosophila melanogaster strains when flies developed in different environments (25 °C and 18 °C). We find a substantial fraction of the transcriptome exhibited genotype by environment interaction, implicating environmentally plastic genetic architecture of gene expression. (nature.com)
  • In 1990, Dr. Hoffmann's lab replaced the grasshopper with the fruit fly, Drosophila melanogaster , and moved on to a genetic dissection of antimicrobial defense. (newswise.com)
  • Here we used electrophysiology and arousal-testing paradigms to show that the fruit fly, Drosophila melanogaster , transitions between deeper and lighter sleep within extended bouts of inactivity, with deeper sleep intensities after ∼15 and ∼30 min of inactivity. (jneurosci.org)
  • Until its appearance, no central, synthesized source of biological data on Drosophila melanogaster was available, despite the fly's importance to science for three decades. (cshlpress.com)
  • To compare appetitive and aversive visual memories of the fruit fly Drosophila melanogaster , we developed a new paradigm for classical conditioning. (frontiersin.org)
  • The wild type Drosophila melanogaster strain Canton S was employed throughout the study. (frontiersin.org)
  • This study used Drosophila melanogaster wing vein and scutellar bristle development to screen Rab proteins predicted to be substrates for ICMT ( Ste14 in flies). (sdbonline.org)
  • Screening more than 200,000 fragments covering the coding sequences of all transcription-related proteins in Drosophila melanogaster, this study identified 195 RDs in known repressors and in proteins not previously associated with repression. (sdbonline.org)
  • This activity combines the popularity of the March Madness basketball pool with a review of the genetics of Drosophila melanogaster , including dominant vs. recessive mutations, chromosome number, sex-linked traits and gene size. (flinnsci.com)
  • Drosophila melanogaster is a powerful model organism for exploring the molecular basis of longevity regulation. (jove.com)
  • The crystal structure of calmodulin (Mr 16,700, 148 residues) from Drosophila melanogaster as expressed in a bacterial system has been determined and refined at 2.2-A resolution. (rcsb.org)
  • Yolk catabolism initiates at cellularization in Drosophila melanogaster embryos. (harvard.edu)
  • What is the characteristics of Drosophila melanogaster? (greatgreenwedding.com)
  • Why are Drosophila melanogaster used in genetics? (greatgreenwedding.com)
  • Drosophila melanogaster, known colloquially as the fruit fly, remains one of the most commonly used model organisms for biomedical science. (greatgreenwedding.com)
  • How many chromosomes does Drosophila melanogaster have? (greatgreenwedding.com)
  • What are the sex differences in Drosophila melanogaster? (greatgreenwedding.com)
  • Lateral view of Drosophila melanogaster showing gender differences. (greatgreenwedding.com)
  • Drosophila melanogaster is an established model for neuroscience research with relevance in biology and medicine. (caltech.edu)
  • Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. (genscript.com)
  • Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. (genscript.com)
  • Sequence finishing and mapping of Drosophila melanogaster heterochromatin. (genscript.com)
  • The Release 5.1 annotation of Drosophila melanogaster heterochromatin. (genscript.com)
  • however, it has not yet been reported in adult Drosophila melanogaster. (lu.se)
  • Drosophila melanogaster is an apt model organism to decipher these behavioural paradigms. (who.int)
  • Although arthropods represent the largest and most diverse animal group, most other Fox genes have not been investigated in detail, not even in the arthropod model species Drosophila melanogaster. (lu.se)
  • He described his scientific journey in the keynote lecture on April 3, 2013, the opening night of the Genetics Society of America's 54th Annual Drosophila Research Conference in Washington, D.C., April 3-7, 2013. (newswise.com)
  • In Dallas, Datta gave a platform talk at the Genetics Society of America's 60th Annual Drosophila Research Conference. (hamilton.edu)
  • The book's appendices include key aspects of Drosophila biology, essential solutions, buffers, and recipes. (cshlpress.com)
  • Biology of Drosophila was first published by John Wiley and Sons in 1950. (cshlpress.com)
  • At OSU, Kernasa will study the biology of the pteromalid wasp and do some foreign exploration of -natural enemies of spotted wing drosophila. (goodfruit.com)
  • Drosophila (/drəˈsɒfɪlə, drɒ-, droʊ-/) is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently)[citation needed] pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. (wikipedia.org)
  • Drosophila species are small flies, typically pale yellow to reddish brown to black, with red eyes. (wikipedia.org)
  • Drosophila species are found all around the world, with more species in the tropical regions. (wikipedia.org)
  • Drosophila made their way to the Hawaiian Islands and radiated into over 800 species. (wikipedia.org)
  • Drosophila species that are fruit-breeding are attracted to various products of fermentation, especially ethanol and methanol. (wikipedia.org)
  • Fruits exploited by Drosophila species include those with a high pectin concentration, which is an indicator of how much alcohol will be produced during fermentation. (wikipedia.org)
  • Males of this genus are known to have the longest sperm cells of any studied organism on Earth, including one species, Drosophila bifurca, that has sperm cells that are 58 mm (2.3 in) long. (wikipedia.org)
  • Wolbachia infections give insight into how certain species of Drosophila are related. (wikipedia.org)
  • Drosophila sechellia has significantly distinct mitochondrial DNA, further emphasizing the evolutionary differences between the three species. (wikipedia.org)
  • Most species are within three major groups, the virilis-repleta radiation, the immigrans-tripunctata radiation and the Hawaiian Drosophila . (wn.com)
  • Studies in Hawaiian Drosophila, Miscellaneous New Species, no. (hawaii.edu)
  • 1975. Studies in Hawaiian Drosophila, miscellaneous new species, no. (hawaii.edu)
  • Drosophila simulans was found later to be closely related to two island endemics, D. sechellia and D. mauritiana. (wikipedia.org)
  • Infections of Wolbachia, a commonly infectious strain of bacteria observed in many insects such as Trichogramma and Muscidifurax uniraptor wasps, are transmitted between generations of Drosophila simulans. (wikipedia.org)
  • Drosophila simulans has also played an important role in sequencing the genomes for certain Wolbachia strains. (wikipedia.org)
  • Among Drosophila simulans inbred males, two fitness characteristics, fertility and attractiveness to females, are especially susceptible to inbreeding depression. (wikipedia.org)
  • Cyclin B Export to the Cytoplasm via the Nup62 Subcomplex and Subsequent Rapid Nuclear Import Are Required for the Initiation of Drosophila Male Meiosis. (nih.gov)
  • The other members of the genus Drosophila also make relatively few giant sperm cells, with that of D. bifurca being the longest. (wikipedia.org)
  • The paraphyletic subgenus Drosophila of the genus Drosophila was first described by Alfred Sturtevant in 1939. (wn.com)
  • Given the versatility of Drosophila as a model organism for genetic screening and analysis, our results suggest that high-throughput behavioral screenings of adult flies can become a valuable tool for investigating the mechanisms behind PPI. (lu.se)
  • Adult flies are trained en masse to differentially associate one of two visual conditioned stimuli (CS) (blue and green light as CS) with an appetitive or aversive chemical substance (unconditioned stimulus or US). (frontiersin.org)
  • In order to understand and compare the mechanisms underlying visual appetitive and aversive memories in Drosophila , we sought to establish a new behavioral paradigm for visual associative learning in adult flies. (frontiersin.org)
  • Furthermore, we found that disruption of the sole Clic Drosophila orthologue significantly blunted sensitivity to alcohol in flies, that mutations in two C. elegans Clic orthologues, exc-4 and exl-1, altered behavioral responses to acute ethanol in worms and that viral-mediated overexpression of Clic4 in mouse brain decreased the sedating properties of ethanol. (nih.gov)
  • The spotted wing drosophila ( Drosophila suzukii ) was first found in California in 2008 and began showing up in Pacific Northwest orchards a couple of seasons ago. (goodfruit.com)
  • Drosophila CIAPIN1 homologue is required for follicle cell proliferation and survival. (nih.gov)
  • Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12). (medlineplus.gov)
  • The courtship song of the Drosophila male serves as a genetically tractable model for the investigation of the neural mechanisms of decision-making, action selection, and motor pattern generation. (nih.gov)
  • I didn't mean to work on courtship behaviour and Drosophila, it was not planned in any way. (webofstories.com)
  • And then I had a long, not debate, it was never printed, it was sort of long arguments in pubs and so on, really, particularly with Margaret Bastock, who was also working on courtship in Drosophila, and she was a student of Tinbergen's at the time. (webofstories.com)
  • for example, some strains can protect against DCV (Drosophila C virus) while other strains cannot. (wikipedia.org)
  • Together, our studies demonstrate key roles for Clic genes in behavioral responses to acute alcohol in Drosophila, C. elegans and mice. (nih.gov)
  • Zhe Han, Ph.D. , Center for Cancer and Immunology Research , and his team of researchers studied nephrotic syndrome (NS) associated genes in the Drosophila model, which included seven genes that had never been analyzed in a pre-clinical model. (childrensnational.org)
  • We report here the functional characterization of Drosophila larval {PCs} with important insights into their cellular uptake pathways. (amrita.edu)
  • The female wasp pierces the drosophila pupa with her long ovipositor and lays one egg per pupa. (goodfruit.com)
  • Title: A genetic screen for maternal-effect suppressors of decapentaplegic identifies the eukaryotic translation initiation factor 4A in Drosophila. (genscript.com)
  • This question has become increasingly relevant since Drosophila became a model of choice for investigating molecular processes associated with sleep in health and disease ( van Alphen and van Swinderen, 2013 ). (jneurosci.org)
  • Using an integrated approach that combined the power of the Drosophila, Caenorhabditis elegans and mouse model systems with bioinformatics analyses, we established a novel, conserved role for chloride intracellular channels (CLICs) in alcohol-related behavior. (nih.gov)
  • Although the amino acid sequences of mammalian and Drosophila calmodulins differ by only three conservative amino acid changes, the refined model reveals a number of significant differences between the two structures. (rcsb.org)
  • The goal of this studentship proposal is to develop a novel Drosophila model to accelerate the translation of genetic findings to a new mechanistic understanding of CHD and to speed up the initial screening of variants for further study. (findaphd.com)
  • The supervisors are experts in Drosophila, chick, mouse and human heart development and the student will gain experience and exposure to be able to connect their work to these other model systems. (findaphd.com)
  • An evolution of Michael Ashburner's 1989 classic Drosophila: A Laboratory Manual, this book is an essential addition to the personal library of Drosophila investigators and an incomparable resource for other research groups with goals likely to require fly-based technical approaches. (cshlpress.com)
  • Drosophila brain structure and function develop and age significantly from larval to adult stage. (wikipedia.org)
  • Analysis of Bub3 and Nup75 in the Drosophila male germline lineage. (bvsalud.org)
  • 2014) produced an authoritative nomenclature for the adult insect brain, using Drosophila as the reference. (caltech.edu)
  • Here, we extend this nomenclature to the adult thoracic and abdominal neuromeres, the ventral nerve cord (VNC), to provide an anatomical description of this major component of the Drosophila nervous system. (caltech.edu)
  • A pteromalid wasp attacks the pupal stage of the spotted wing drosophila. (goodfruit.com)
  • The wasp has been found in cherries, cotoneaster, and snowberry and has been reared on spotted wing drosophila in the laboratory. (goodfruit.com)
  • In most cases, just the spotted wing drosophila emerged from the fruit, but both the spotted wing drosophila and the wasp emerged from the cherries. (goodfruit.com)
  • Although the spotted wing drosophila has natural enemies in Asia, where it originated, Shearer thinks it likely that the wasp is endemic to the United States. (goodfruit.com)
  • It's not known yet if it also attacks the common vinegar fly, nor is it known how much help the wasp might be in controlling drosophila. (goodfruit.com)
  • Oregon State University has hired a doctoral student from Thailand to research -natural enemies of the spotted wing drosophila, including the pteromalid wasp. (goodfruit.com)
  • Until recently, research on the Drosophila brain was hindered by the lack of a complete and uniform nomenclature. (caltech.edu)
  • Abstract The Drosophila genome is subject to a high degree of selection, especially unusually widespread negative selection compared to other taxa. (wikipedia.org)
  • Our results show that sleep is not homogenous in insects, and suggest that waking behavior and the associated synaptic plasticity mechanisms determine the timing and intensity of deep sleep stages in Drosophila . (jneurosci.org)
  • It might be a parasitoid that goes after other insects and targeted drosophila when the fly arrived. (goodfruit.com)
  • The aim is to create a nomenclature, definitions, and spatial boundaries for the Drosophila VNC that are consistent with other insects. (caltech.edu)
  • These results provide a basis for future investigations into the cellular and molecular mechanisms underlying visual memory and perception in Drosophila . (frontiersin.org)
  • the invaluable handbook and guide for generations of Drosophila workers. (cshlpress.com)
  • She is a specialist in biological control and has worked with the spotted wing drosophila in -Thailand. (goodfruit.com)
  • The research team concluded that the Drosophila nephrocyte can be used to illuminate the clinically relevant molecular mechanisms underlying the pathogenesis of most monogenic forms of NS. (childrensnational.org)
  • Title: Identification of the Drosophila eIF4A gene as a target of the DREF transcription factor. (genscript.com)
  • The wasp's life cycle takes about three times as long as that of the drosophila, but Shearer said parasitic wasps normally have a longer developmental time than their hosts. (goodfruit.com)
  • She presented her work on temporal gene regulation during development in a talk titled "The contributions of optimal and suboptimal Bcd and Otd DNA binding sites to enhancer activity in the Drosophila embryo. (hamilton.edu)
  • Datta's research group focuses on Drosophila embryo and eye development. (hamilton.edu)
  • What I was working on, which was really a project that I'd chosen myself, was the effects of inbreeding in general, but particularly, I mean, using Drosophila as an experimental animal, and I was looking at the effects of inbreeding on fertility and rate of development and size and longevity and so on. (webofstories.com)
  • eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary. (genscript.com)
  • To improve our understanding of these processes, we analysed the function of the mitotic checkpoint complex (MCC) component Bub3 and the nucleoporin Nup75, a component of the nuclear pore complex realizing the transport of signalling effector molecules to the nucleus, in the Drosophila testis . (bvsalud.org)
  • It was first thought that the spotted wing drosophila might not be able to survive the cold winters of the Pacific Northwest, but Shearer said that even as late as last November, they found cherries still hanging on the trees that were infested with the pest. (goodfruit.com)
  • We installed New Drosophila specific gene-finding HMM based program FGENESH for multiple gene prediction in genomic DNA It is available at http://genomic.sanger.ac.uk/ of our Computational Genomic Group WEB server ( http://genomic.sanger.ac.uk/gf/gf.html ) For analysis of Drosophila DNA FGENES or FGENESH versions for human DNA can be used, however Drosophila specific version has better exact exon prediction accuracy. (bio.net)