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  • genes
  • HLA genes, islet autoantibodies and residual C-peptide were studied to determine the independent association of each exposure with diabetic retinopathy (DR), 15 years after the clinical onset of type 1 diabetes in 15-34 year old individuals. (pubmedcentralcanada.ca)
  • DRB4
  • In fact, if one looks carefully, there are both data and hints on a possible DR53/DRB4 association in childhood leukaemia and other leukaemias in previously published papers. (dorak.info)
  • Together with the results of our studies in chronic myeloid leukaemia (CML) 14 and CLL 15 , it can be concluded that whichever leukaemia has been investigated with the consideration of DR53/DRB4 as a possible risk factor, either an association or a hint of an association have been found depending on the way the data are analysed. (dorak.info)
  • The HLA-DRB4 promoter polymorphism is associated with differential expression of this locus 4 and this occurs at the level of mRNA production 3 . (dorak.info)
  • In HLA-DRB4, allelic differences occur and are not limited to exon 2 ( b 1 domain) but involve exon 3 ( b 2 domain) too. (dorak.info)
  • For the alignment of DRB4 allelic sequences, see the IMGT/HLA Sequence Database alignment page . (dorak.info)
  • peptides
  • Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ. (nih.gov)
  • WT1 peptides 328-349 and 423-441 are able to stimulate a peptide-specific CD4 + response that can recognize WT1 + tumor cells in multiple HLA-DRB1 settings as determined by IFN-γ enzyme-linked immunospot assays. (aacrjournals.org)
  • Cross-priming experiments showed that antigen-presenting cells pulsed with either mesothelioma or leukemia tumor lysates can process and present each of the CD4 + peptides identified. (aacrjournals.org)
  • gene
  • HLA-DR53 is not expressed on the HLA-B57DR7Dw11DQ9 (DQA1*02:01, DQB1*03:03) haplotype (as in the cell line DBB (IHW 9052) representing the conserved extended haplotype (CEH) 57.1) due to a base substitution at the 3' end of the first intron of the gene 9;10 . (dorak.info)
  • Alaturi de genele clasice, in regiunea MHC I mai sunt incluse gene cu un polimorfism redus desemnate ca HLA-E, HLA-F si HLA-G 2;8 . (synevo.ro)
  • risk
  • Pretransplant C3d-Fixing Donor-Specific Anti-HLA Antibodies Are Not Associated with Increased Risk for Kidney Graft Failure. (nih.gov)