Down-RegulationApoptosisDown SyndromeCell Line, TumorRNA, MessengerCell LineCells, CulturedProto-Oncogene Proteins c-bcl-2CaspasesSignal TransductionCaspase 3Gene Expression RegulationGene Expression Regulation, NeoplasticCell ProliferationReverse Transcriptase Polymerase Chain ReactionBlotting, WesternTumor Cells, CulturedMolecular Sequence DataFlow CytometryDNA FragmentationCell SurvivalRNA, Small InterferingDose-Response Relationship, DrugPhorbol EstersRNA InterferenceIn Situ Nick-End LabelingTime FactorsGene Expression ProfilingAntigens, CD46Phorbol 12,13-DibutyrateKineticsEnzyme ActivationTumor Suppressor Protein p53Cell DivisionPhosphorylationTransfectionbcl-2-Associated X ProteinGene ExpressionCell DifferentiationBase SequencePlant ExtractsTranscription, GeneticCell CycleImmunohistochemistryReceptors, Cell SurfaceCitric AcidProtein Kinase CMice, Inbred C57BLAntigens, CD95Receptor, InsulinDNAPhagocytosisAmino Acid SequencePhorbolsAntineoplastic AgentsCaspase InhibitorsTetradecanoylphorbol AcetateMacrophagesEnzyme InhibitorsMutationCaspase 9Apoptotic Protease-Activating Factor 1Membrane ProteinsMitochondriaOligonucleotide Array Sequence AnalysisAnnexin A5Tumor Necrosis Factor-alphaFibroblastsPromoter Regions, GeneticDisease Models, AnimalUp-RegulationCarrier ProteinsNeoplasm ProteinsTranscription FactorsNecrosisPregnancyHeLa CellsJurkat CellsRats, WistarApoptosis Regulatory ProteinsProto-Oncogene Proteins c-aktBinding SitesCell NucleusCell MembraneTropaeolaceaeMeasles virusCytochromes cCaspase 8Antigens, CDPhosphatidylserinesMice, Inbred BALB CDNA-Binding ProteinsGene SilencingEpithelial CellsLiverT-LymphocytesCell MovementRats, Sprague-DawleyCell DeathRecombinant Proteins