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  • tissues
  • The sequence of experiments is designed to first explore the influence of iron load on the response and demonstrate that HFE knockout mice are more sensitive than the wild type to radiation-induced cancer in one or more of three target tissues (liver, colon and breast). (unt.edu)
  • Gamma Rays
  • The goal of this research is to establish a more mechanistic approach to estimating risk and to answer questions, including whether HZE effects can be scaled from those of gamma rays, whether risk is linear with low dose-rate, and how individual radiation sensitivity impacts the risks for astronauts, a population that is selected for many factors related to excellence in health. (wikipedia.org)
  • At doses above a few Gy, detrimental CNS changes occur in humans who are treated with radiation (e.g., gamma rays and protons) for cancer. (wikipedia.org)
  • dosage
  • Wing has quarreled with an assumption regarding the dosage of radiation the populate sustained. (albionmonitor.com)
  • The former means dosage or amount of dose administered to a person, whereas the latter means the time-dependent concentration (often in the circulatory blood or plasma) or concentration-derived parameters such as AUC (area under the concentration curve) and Cmax (peak level of the concentration curve) of the drug after its administration. (wikipedia.org)
  • In biological warfare infective dosage is the number of infective doses per minute for a cubic meter (e.g. (wikipedia.org)
  • toxicology
  • In toxicology, hormesis is a dose response phenomenon characterized by a low dose stimulation, high dose inhibition, resulting in either a J-shaped or an inverted U-shaped dose response. (wikipedia.org)
  • In 2010, a paper published in the journal Environmental Toxicology & Chemistry showed that low doses of methylmercury, a potent neurotoxic pollutant, improved the hatching rate of mallard eggs. (wikipedia.org)
  • chemotherapy
  • Recent interim analysis of the HD11 trial of the GHSG: intensification of chemotherapy and reduction of radiation dose in early unfavorable stage Hodgkin's lymphoma. (springer.com)
  • Ten-year results of a German Hodgkin Study Group randomized trial of standard and increased dose BEACOPP chemotherapy for advanced Hodgkin lymphoma (HD9). (springer.com)
  • Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease. (springer.com)
  • Dose escalation of BEACOPP chemotherapy for advanced Hodgkin's disease in the HD9 trial of the German Hodgkin's Lymphoma Study Group (GHSG). (springer.com)
  • toxins
  • It is conjectured that low doses of toxins or other stressors might activate the repair mechanisms of the body. (wikipedia.org)
  • mortality
  • The modulation of the cell defense mechanisms according to the dose, dose rate, the type and number of lesions, the physiological condition of the cell, and the number of affected cells explains the large variations in radiosensitivity (variations in cell mortality or the probability of mutations per unit dose) depending on the dose and the dose rate that have been observed. (blogspot.com)
  • Mortality and Radiation Dose, 1950-1966" ( TR-11-70 ). (ratical.org)
  • Mortality and Radiation Dose, 1950-1974" (RERF TR-1-77 ). (ratical.org)
  • The response may be a physiological or biochemical response, or even death (mortality), and thus can be counts (or proportion, e.g., mortality rate), ordered descriptive categories (e.g., severity of a lesion), or continuous measurements (e.g., blood pressure). (wikipedia.org)
  • IONIZING-RADIATION
  • progress in radiobiology has shown that a cell is not passively affected by the accumulation of lesions induced by ionizing radiation. (blogspot.com)
  • 3. Ionizing radiation--Health aspects. (ratical.org)
  • The thyroid gland of children is especially vulnerable to the carcinogenic action of ionizing radiation. (semanticscholar.org)
  • This work is based on knowledge about dose-response relationships and ionizing radiation exposure of the general population. (irsn.fr)
  • These radioactive particles are by-products generated as a result of activities related to nuclear energy and constitute a pollution and a radiotoxicity problem (with serious health and ecological consequences) due to its unstable nature of ionizing radiation emissions. (wikipedia.org)
  • Cataracts have been associated with ionizing radiation such as X-rays. (wikipedia.org)
  • Radiation hormesis is the hypothesis that low doses of ionizing radiation (within the region of and just above natural background levels) are beneficial, stimulating the activation of repair mechanisms that protect against disease, that are not activated in absence of ionizing radiation. (wikipedia.org)
  • The sievert (symbol: Sv) is a derived unit of ionizing radiation dose in the International System of Units (SI) and is a measure of the health effect of low levels of ionizing radiation on the human body. (wikipedia.org)
  • He is best known for his work in the field of ionizing radiation response on Bipolar junction transistor (BJT) and Enhanced Low Dose Rate Sensitivity in BJT. (wikipedia.org)
  • Response of advanced bipolar processes to ionizing radiation EW Enlow, RL Pease, W Combs, RD Schrimpf, RN Nowlin Nuclear Science, IEEE Transactions on 38 (6), 1342-1351. (wikipedia.org)
  • Infections caused by ionizing radiation can be endogenous, originating from the oral and gastrointestinal bacterial flora, and exogenous, originating from breached skin following trauma. (wikipedia.org)
  • Up to 10% of invasive cancers are related to radiation exposure, including both ionizing radiation and non-ionizing radiation. (wikipedia.org)
  • Ultraviolet's position on the electromagnetic spectrum is on the boundary between ionizing and non-ionizing radiation. (wikipedia.org)
  • mutations
  • the probable mechanism is radiation-induction of mutations in the coronary arteries, resulting in dysfunctional clones (mini-tumors) of smooth muscle cells. (ratical.org)
  • Radiography
  • In March-August 1962, a radiation incident in Mexico City occurred when a ten-year-old boy took home an unprotected industrial radiography source. (wikipedia.org)
  • Four people died from overexposure to radiation from a 5-Ci cobalt-60 capsule, an industrial radiography orphaned source that was not contained in its proper shielding. (wikipedia.org)
  • cells
  • Peripheral blood mononuclear cells (PBMCs) were used to identify sensitive and robust gene-based biomarkers of α-particle radiation exposure. (nih.gov)
  • Cells were isolated from healthy individuals and were irradiated at doses ranging from 0-1.5 Gy. (nih.gov)
  • Dataset is obtained from qPCR results in isolated white blood cells exposed to α-particle and X-ray radiation. (nih.gov)
  • It depicts the relationship between the fraction of cells retaining their reproductive integrity and the absorbed dose of radiation. (wikipedia.org)
  • Such phytochemicals trigger hormetic responses in brain cells which can improve brain function and may increase the resistance of neurons to injury and age-related neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. (wikipedia.org)
  • However, the heavy ion component of space radiation presents distinct biophysical challenges to cells and tissues as compared to the physical challenges that are presented by terrestrial forms of radiation. (wikipedia.org)