For such unresectable recurrences, conventional radiotherapy with or without chemotherapy can be considered. (frontiersin.org)
However, conventional radiotherapy is limited due to the presence of critical normal structures, such as small bowel, kidneys, and spinal cord, and further radiation can lead to unacceptable toxicity. (frontiersin.org)
Concurrent chemotherapy1
Received weekly cisplatin 40 mg m2 for 5 to 6 cycles as concurrent chemotherapy with radiation therapy. (who.int)
Tumor4
Radiation is directed at the tumor from a source outside the body to kill the cancer cells. (epnet.com)
But in a small study in children with a rare kidney tumor, lower doses may have no effect . (kevinmd.com)
Induction chemotherapy is typically given to patients with stage III-IVB disease in order to shrink a primary tumor to reduce its bulkiness in preparation for future surgery or radiation therapy. (medscape.com)
Because of the change in her hearing, the cisplatin was removed from the remaining two cycles of chemotherapy called for in her protocol. (alexslemonade.org)
The last dose of cisplatin must be administered prior to, or concurrently with, the final dose of radiation. (who.int)
Head and neck1
Survivors who had head and neck tumors treated with higher doses of radiation and/or older radiation techniques (from the 1950s and 1960s) often develop hearing loss. (alexslemonade.org)
Postoperative radiation1
In order to achieve a more effec- were recommended postoperative radiation and adjuvant tive and individualised chemotherapeutic treatment of breast chemotherapy. (lu.se)
Neck1
Selected patients with advanced or metastatic disease may receive additional therapy (radiation or neck dissection) depending on their response to first-line therapy. (medscape.com)
Therapy13
While robotic surgery allows for more precise and optimal preservation of the organs and surrounding tissue, there is still concern with the toxicities from the chemotherapy and consequences of tissue damage from radiation therapy, particularly in a younger population. (nursingcenter.com)
Patients at high risk were assigned to usual high-dose radiation therapy plus chemotherapy. (nursingcenter.com)
Radiation therapy uses a controlled dose of radiation to kill cancer cells or damage them so they cannot grow and multiply. (cancervic.org.au)
Radiation therapy to the pelvic area (for cancer of the rectum, bladder, cervix, uterus or vagina) can stop the ovaries producing hormones. (cancervic.org.au)
Radiation therapy to the pelvic area can also affect the uterus, make sexual intercourse uncomfortable, and increase the risk of miscarriage, premature birth and low birth weight. (cancervic.org.au)
Radiation therapy to the brain may damage the pituitary gland, which releases hormones that tell the ovaries to release an egg each month. (cancervic.org.au)
If you are treated with both chemotherapy and radiation therapy (chemoradiation), the risk of infertility is higher. (cancervic.org.au)
Stem cell transplant - high-dose chemotherapy and, possibly, radiation therapy are given before the transplant to kill the cancer cells in the body. (cancervic.org.au)
The risk of permanent infertility after high-dose chemotherapy or radiation therapy is high. (cancervic.org.au)
Large doses of chemotherapy and/or radiation therapy are then applied to kill the cancer cells. (epnet.com)
In essence, a bone marrow transplant uses very high doses of therapy in attempt to cure the cancer. (ucsfhealth.org)
Recently, stereotactic body radiation therapy (SBRT) has attracted much attention. (frontiersin.org)
Thus, SBRT has gradually become an attractive radiation therapy technology, and been widely used in the treatment of pancreatic cancer ( 14 , 15 ). (frontiersin.org)
Cancers4
Most throat cancers caused by HPV have good outcomes, and the cancer doesn't return or spread to other parts of the body after treatment," said Ferris, who also is Professor in the Departments of Otolaryngology, of Immunology, and of Radiation Oncology at the University of Pittsburgh School of Medicine. (nursingcenter.com)
Radiation is often a key part of cancer treatment for cancers of the esophagus, stomach or pancreas - all near the spleen. (kevinmd.com)
But we don't even know what dose the spleen receives in abdominal cancers, because it hasn't been published. (kevinmd.com)
I tried publishing a small IRB-exempt study measuring spleen dose for abdominal cancers, but peer reviewers at two journals didn't see the relevance. (kevinmd.com)
Following robotic surgery, patients with HPV-associated throat cancer would typically undergo high-dose radiation and chemotherapy. (nursingcenter.com)
For patients at low and intermediate risk, the 2-year, progression-free survival rate was approximately 95 percent, and reducing radiation or chemotherapy intensity did not increase the risk of recurrence. (nursingcenter.com)
Publications on infection from spleen radiation date back at least thirty years, but were limited to lymphoma and postsplenectomy patients. (kevinmd.com)
Vaccination rates have improved when the spleen is surgically removed , but for cancer patients receiving radiation over half may not receive pneumococcal vaccination . (kevinmd.com)
In the U.S., thousands of abdominal cancer patients may receive incidental spleen radiation each year. (kevinmd.com)
According to the latest update of a key cancer textbook, all patients receiving spleen radiation should receive pneumococcal vaccination. (kevinmd.com)
And the textbook broadly applies the recommendation to all cancer patients, many of whom may qualify based on age or receiving chemotherapy . (kevinmd.com)
A total of 22 patients received SBRT with a median prescribed dose of 40 Gy (range of 30-50 Gy)/4 to 7 fractions. (frontiersin.org)
SBRT combined with chemotherapy for the treatment of locally advanced pancreatic cancer can effectively control local tumors and alleviate local symptoms, prolong the overall survival of patients, and has tolerable toxicity ( 16 - 19 ). (frontiersin.org)
Kidney1
which may render the genetic mate doses of NDMA is the kidney, but a Transplacental carcinogenesis rial of fetal cells highly accessible to much lower incidence of tumours is stu dies with ENU in nonhuman pri carcinogens. (who.int)
Recurrence1
a) Malignancy treated with curative intent with no known active disease =2 years before the first dose of study intervention and of low potential risk for recurrence. (who.int)
Frozen1
For autologous transplantation, the patient receives his or her own bone marrow or stem cells that were collected and frozen before admission for high-dose chemotherapy or radiation. (ucsfhealth.org)
High5
It may also be used to help people who have been exposed to high doses of radiation. (chemocare.com)
Ears and hearing can be damaged by chemotherapy, high-dose radiation, and some antibiotics. (alexslemonade.org)
Outer ear infections, which are common after high-dose radiation, can impair hearing by drying out and thickening the external ear canal and eardrum. (alexslemonade.org)
With Hodgkin's lymphoma, high doses to the spleen can cause atrophy . (kevinmd.com)
Effective dose1
Most experimental studies of the predominant results of earlylife do not develop in rats exposed to the carcinogenesis during prenatal life exposure are what would be expect same carcinogen during adult life and infancy have been conducted ed from a higher effective dose to the (Diwan and Rice, 1995 ). (who.int)
Recurrent1
and first-, second-, and third-line chemotherapy for metastatic or recurrent disease. (medscape.com)
Pregnancy1
It's been used safely during pregnancy in doses of up to 600 mg daily for up to 4 weeks. (medlineplus.gov)
Treatment6
A less intense treatment for human papillomavirus positive (HPV+) throat cancer-using robotic surgery followed by low-dose radiation-could provide as much benefit as standard higher-dose radiation and chemotherapy while preserving a patient's throat function, and with potentially less toxicities, according to researchers at UPMC Hillman Cancer Center and Yale Cancer Center. (nursingcenter.com)
Having chemotherapy can cause your periods to become irregular or even stop for a while, but they often return to normal within a year of finishing treatment. (cancervic.org.au)
If your ovaries don't need treatment, one or both may be surgically moved higher in the abdomen and out of the field of radiation. (cancervic.org.au)
They are removed from circulating blood before chemotherapy or radiation treatment. (epnet.com)
Radiation oncologists offer curative cancer treatment to many. (kevinmd.com)
According to treatment guidelines in the regional care pro- recur in spite of chemotherapy. (lu.se)
Stem1
Children treated with less than 2400 cGy of cranial radiation (e.g., for leukemia or prior to stem cell transplantation) rarely develop any late effects in the ears. (alexslemonade.org)
24001
Seizures, vomiting, and unconsciousness have been reported for children aged 14 months to 16 years who took up to 2400 mg of alpha-lipoic acid as a single dose. (medlineplus.gov)
Marrow2
When these higher doses are used to kill the cancer cells, the normal bone marrow cells will also be destroyed. (ucsfhealth.org)
Therefore, the types of ious forms of radiation, carcinogen ifested as a higher incidence of the tumours that occur during childhood ic infectious agents, and chemicals same kinds of tumours that occur in in humans, including various embry and chemical mixtures. (who.int)
Lower1
Lower doses of alpha-lipoic acid don't seem to work. (medlineplus.gov)
Occur1
These mutations can occur as a result of exposure to radiation or cancer-causing chemicals. (epnet.com)
Risk3
PEGFILGRASTIM (PEG fil gra stim) lowers the risk of infection in people who are receiving chemotherapy. (chemocare.com)
The risk of infertility will vary depending on the area treated, the dose of radiation and the number of treatments. (cancervic.org.au)
Children most at risk for chemotherapy-caused hearing loss are those treated for brain tumors, germ cell tumors, osteosarcoma, and neuroblastoma. (alexslemonade.org)
Drugs3
Chemotherapy uses drugs to kill or slow the growth of cancer cells. (cancervic.org.au)
Some chemotherapy drugs can affect your heart and lungs. (cancervic.org.au)
Chemotherapy involves the use of drugs to kill cancer cells. (epnet.com)
Exposure1
Studies in experimental incidence and multiplicity of tumours to Wilms tumour in humans - in the animals increase and the latency period de adult rat after perinatal exposure to a creases with increasing dose. (who.int)
Damage2
The doctors think that some of the chemotherapy side effects-including the hearing loss-were a result of the chemotherapy compounding damage already done by the radiation. (alexslemonade.org)
Chronic middle ear infections (otitis media) can also be caused by radiation due to damage to the eustachian tube, which is responsible for drainage of the middle ear. (alexslemonade.org)
Daily1
Alpha-lipoic acid is possibly safe in children aged 10-17 years when taken by mouth in doses up to 600 mg daily for 3 months. (medlineplus.gov)
Body2
Tell your care team immediately if you suspect that the On-body Injector may not have performed as intended or if you suspect the use of the On-body Injector resulted in a missed or partial dose. (chemocare.com)
If you miss a dose due to an On-body Injector failure or leakage, a new dose should be administered as soon as possible using a single prefilled syringe for manual use. (chemocare.com)
Total1
i A total dose of 45 Gy for EBRT to the pelvis ii If brachytherapy is used, normal tissues should be limited with 2 cc rectal dose 75 Gy, sigmoid 2 cc dose 75 Gy, and 2 cc bladder dose 90 Gy. (who.int)