Dose of sufentanil. Medical search. Frequent questions

Epidural analgesia combined with inhalatory anesthesia may provide advantages over the conventional routes of analgesic administration (intravenous or intramuscular), including reduction of the doses of the inhalant agents required to produce anaesthesia and thus the side effects derived from higher doses 1 1. (scielo.br)
Epidural methadone in dogs undergoing pelvic limb surgical procedures resulted in greater decreases in the EtISO required to maintain anesthesia compared with the same doses administered intravenously 2 2. (scielo.br)
Epidural anesthesia with bupivacaine, bupivacaine and fentanyl, or bupivacaine and sufentanil during intravenous administration of propofol for ovariohysterectomy in dogs. (scielo.br)
The intended anesthesia included 5 micrograms of intrathecal sufentanil and an epidural test dose of 4 ml 1.5% lidocaine with 1:200,000 epinephrine. (ahrq.gov)
About one hour later, the anesthesia care provider's audit of the controlled substance box found that this patient had been given intrathecal morphine 1 mg instead of 5 micrograms sufentanil. (ahrq.gov)
The conventional dose of remifentanil combined with dexmedetomidine anesthesia has a good anesthetic effect in clinical applications, but at the same time, drug-related side effects are strong, and even excessive sedation of patients occurs, which is not conducive to patient safety [ 4 ]. (hindawi.com)
Methods such as intrathecal adjuvant opioid use to reduce the total dose of anaesthetics delivered, 8 prophylactic use of vasopressors, 4,9 and the use of intravenous (IV) pre-load colloid liquid 10 have been proposed to reduce the incidence or extent of maternal hypotension after spinal anesthesia during cesarean delivery. (researchsquare.com)
There is evidence that acupuncture anesthesia can decrease mortality after OP-CABG, while reducing the dose of anesthesia required, minimizing surgical complications, and decreasing medical costs. (clinicaltdd.com)
The primary outcome is the dose of sufentanil used for anesthesia. (clinicaltdd.com)
Secondary outcomes are cardiac troponin I content, inotropic score, dose of propofol used for anesthesia, duration of mechanical ventilation, duration of stay in the intensive care unit, length of postoperative hospital stay, incidence of overall complications within 30 days of surgery, and incidence of overall mortality within 30 days of surgery. (clinicaltdd.com)
I find that the patients tend to have a smooth emergence with TIVA, similar to emergence under volatile anesthesia with a heavy dose of opioids (or alternatively if I've bolused precedex during the case for opioid sparing). (studentdoctor.net)

Determination of the analgesic dose-response relationship for epidural fentanyl and sufentanil with bupivacaine 0.125% in laboring patients. (scielo.br)
10. Abelson AL, Armitage-Chan E, Lindsey JC, Wetmore LA. A comparison of epidural morphine with low dose bupivacaine versus epidural morphine alone on motor and respiratory function in dogs following splenectomy. (scielo.br)
He was placed on a solution of 0.25% bupivacaine with 3 m fentanyl/cc at a bolus dose of 3.5 cc with a 180 minute lockout time. (ispub.com)
This study assesses the effect of intrathecal adjuvant bupivacaine plus sufentanil on intraoperative hemodynamic changes in elective coronary artery bypass surgery. (longdom.org)
One group received intrathecal sufentanil (S) and the other group received the same dose of sufentanil plus supplemental bupivacaine (SB). (longdom.org)
The administration of intrathecal sufentanil plus bupivacaine seems to keep the hemodynamic status of the patients more stable than intrathecal sufentanil alone. (longdom.org)
This study evaluated the influence of bupivacaine bolus concentration and a 3-ml 1.5% lidocaine-epinephrine test dose, on analgesic effectiveness and the ability to walk after block placement. (silverchair.com)
and group B.125 received 15 ml bupivacaine, 0.125% (no test dose). (silverchair.com)
Bupivacaine, 0.0625%, with 0.33 microg/ml sufentanil was infused throughout labor at 13.5-15 ml/h. (silverchair.com)
A bolus of 0.125% bupivacaine containing sufentanil, without a previous test dose, proved to be optimal with respect to analgesia and early ambulation. (silverchair.com)
When a test dose was given before bupivacaine, 0.125%, fewer women walked within 1 h of block placement. (silverchair.com)
Omitting a lidocaine-epinephrine test dose and using 0.125% bupivacaine for the initial bolus should permit ambulation in the early postblock period for most parturients who elect this option. (silverchair.com)
This study was designed to evaluate analgesic effectiveness and the ability to walk after a bolus of either bupivacaine, 0.0625%, or bupivacaine, 0.125% (with sufentanil), with or without previous administration of the traditional lidocaine-epinephrine test dose. (silverchair.com)
Background:The aim of this prospective, double blind, randomised trial was to compare the analgesic and adverse effectsof three concentrations of the thoracic epidural sufentanil with bupivacaine in patients undergoing thoracotomy.Methods:We studied 60 (randomised) patients who were to receive a 10 ml bolus dose of sufentanil, 1µg/ml, 2 µg/ml and3 µg/ml, in bupivacaine 0.125%, via thoracic epidural. (bvsalud.org)

It contains 30 micrograms of a synthetic opioid painkiller known as sufentanil, which is 5 to 10 times more potent than fentanyl, and 1,000 times more potent than morphine. (healthline.com)
This study was designed to investigate the effects of dezocine, morphine and sufentanil on both intestinal smooth muscle contraction and propulsion in rats. (medsci.org)
Contractile tension and frequency of isolated rat small intestine smooth muscle were measured using tension transducer after incubation with different concentrations of dezocine, morphine and sufentanil. (medsci.org)
The propulsive rate of methylene blue in rat intestinal tract was measured 30 minutes after intraperitoneal injection of morphine, sufentanil and dezocine. (medsci.org)
Morphine and sufentanil significantly increased the contractile tension of isolated small intestine smooth muscle at high doses. (medsci.org)
The propulsive rate of methylene blue in intestinal tract was significantly decreased after the treatment with morphine, sufentanil and dezocine (45.6%, 43.7%, and 42.1% respectively) compared to control group(57.1%), while the difference among the 3 drug groups were not significant. (medsci.org)
Morphine and sufentanil may dose dependently increase the contractile tension and contraction ability of isolated rat small intestine smooth muscle, while dezocine has no significant effect on intestine smooth muscle contraction. (medsci.org)
Patients who have undergone a replacement of the same knee or hip, or "who have taken an opioid for more than 30 consecutive days, at a daily dose of 15 mg or more of morphine (or equivalent), within the past 3 months prior to surgery," are ineligible. (hcplive.com)
An increase in illicit fentanyl production and distribution - it is often mixed into heroin or cocaine - has led to a spike in opioid overdose deaths around the United States because fentanyl and its analogs, like sufentanil, are much more potent than morphine and heroin. (serenityatsummit.com)
Dextromethorphan produced lower ED(50) values for morphine, fentanyl and sufentanil but exerted no effect on the potency of SNC80 or U50,488H. (erowid.org)
Similarly, ketamine potentiated the antinociceptive potency of morphine, fentanyl and sufentanil but not SNC80 or U50,488H. (erowid.org)

It has a faster recovery time compared to midazolam and has a reduced incidence of post-operative excitement and results in a reduction in dose required of propofol and thiopental. (wikipedia.org)
We examined whether IV lidocaine reduces the dose of propofol and the occurrence of adverse events during gastroscopy in elderly patients. (dovepress.com)
IV lidocaine reduced the total and maintenance propofol dose in Group L ( p (dovepress.com)
There were no significant dose-dependent changes in blood pressure in either the ciprofol or propofol groups. (theanesthesiaconsultant.com)
Secondary end point(s): - Difficulty of orotracheal intubation o Intubation Difficulty Scale (IDS) score (Appendix 2) for complexity of endotracheal intubation28 o Percentage of patients who required re-ventilation after a failed first attempt at intubation o Percentage of patients who received an additional dose of propofol at induction o Percentage using the emergency protocol established by the study. (who.int)

Sufentanil analgesia following cesarean section: epidural versus intravenous administration. (scielo.br)
If the patient had VAS scores above 2 or needed an extra epidural rescue bolus before delivery, a higher dose was used for the next patient. (researchsquare.com)

In the postoperative period, VAS and Colorado analgesic scores were lower for the dogs that received the higher nalbuphine dose, which only required supplemental analgesia 10 h following its administration, compared with dogs that received the lower dose. (scielo.br)
Palmer CM, Cork RC, Hays R, Van Maren G, Alves D. The dose-response relation of intrathecal fentanyl for labor analgesia. (scielo.br)
The company submitted a supplemental new drug application (sNDA) for the proposed indication - "single-dose infiltration to produce local analgesia and as a nerve block to produce regional analgesia" - on May 5, 2014. (medscape.com)

If a strong association exists between TBW or BMI and pain response, it will lend support for the importance of taking body size or composition into account when making decisions about hydromorphone dosing in the ED. It will lay the groundwork for future studies of analgesic dosing. (hcplive.com)
Dsuvia is a new brand name for a prescription opioid painkiller , sufentanil, which is a very potent narcotic analgesic. (serenityatsummit.com)

A spinal dose of ropivacaine 12 mg with single intravenous 0.15 mg/kg bolus dose of S-ketamine may significantly reduce the risk of hypotension and provide sedative status before delivery, thus the method could be cautiously used in parturients with high risks of hypotension or extreme nervousness. (researchsquare.com)

Secondary outcome measures included a reduction of intraoperative mean arterial pressure (MAP) >20% from baseline, intraoperative and postoperative sufentanil consumption, length of stay in the ICU, incidence of postoperative nausea and vomiting (PONV), time to first faeces, postoperative pain at 24 h after surgery, time to extubation and the length of hospital stay. (bvsalud.org)
Perioperative sufentanil consumption, the incidence of PONV and intraoperative MAP reduction >20% from baseline, length of stay in the ICU, postoperative pain at 24 h after surgery, time to extubation and the length of hospital stay were significantly decreased in the TTM group. (bvsalud.org)

Alvimopan is contraindicated in opioid tolerant patients (ie, those who have taken therapeutic doses of opioids for >7 consecutive days immediately prior to taking alvimopan). (medscape.com)
Although Dsuvia's primary ingredient, sufentanil, is a Schedule II medication, opioid drugs related to it (like fentanyl) have been diverted, produced illicitly, and widely abused. (serenityatsummit.com)
The body quickly becomes tolerant to opioid drugs, so people with chronic pain who need consistent relief must work with their doctor over time to raise the dose of their opioid medication or switch to something more potent. (serenityatsummit.com)

Investigators will evaluate the efficacy and safety of the Sufentanil NanoTab PCA System/15 mcg for the management of acute postoperative pain after total unilateral knee or total unilateral hip replacement surgery. (hcplive.com)
This trial protocol will determine whether acupuncture at distal-proximal or regional acupoints can reduce anesthetic dose and postoperative complications in OP-CABG surgery, with the purpose of ensuring patient safety in the perioperative phase. (clinicaltdd.com)

DSUVIA® (Sublingual Sufenanil): an enteral form of sufentanil FDA approved for management of moderate to severe pain. (asda.org)
Dsuvia, in particular, and sufentanil in general, is designed to treat acute, severe pain when other pain medications are ineffective. (serenityatsummit.com)

Doses of 50 MME or more increases the risk of overdose, depending on whether a person has taken other opioids before. (serenityatsummit.com)
Using a mouse hot-plate test, dose-response relationships were first determined for all compounds individually and then for opioids co-administered with fixed doses of ketamine or dextromethorphan. (erowid.org)

The risks of physiological dependence and withdrawal increase with longer treatment duration and higher daily dose. (pdr.net)
Reduce the dose to 300 mg once daily if the daily dose is already 600 mg. (emedz.net)
In post-marketing experience, heart failure was more frequently reported in patients receiving a total daily dose of 400 mg although there were also cases reported among those receiving lower total daily doses. (druginteractionchecker.com)

The purpose of the study was to determine the optimal dose of spinal ropivacaine for cesarean section with or without intravenous single bolus of S-ketamine and to observe the incidences of hypotension of both methods. (researchsquare.com)

In normal volunteers, single intravenous doses of 0.15 mg/kg of ondansetron had no effect on esophageal motility, gastric motility, lower esophageal sphincter pressure, or small intestinal transit time. (nih.gov)

But at the same time, the head of FDA's own advisory committee warned the administration that approval of the new version of sufentanil will only make overdoses that much more likely. (healthline.com)
CDC's OD2A program collects data on unintentional and undetermined intent drug overdoses: 1) nonfatal overdoses treated in EDs from the Drug Overdose Surveillance and Epidemiology (DOSE) system, and 2) overdose deaths from the State Unintentional Drug Overdose Reporting System (SUDORS). (cdc.gov)

Sufentanil is given as a mild course with minimal toxicity peripheral neuropathy, encephalitis, and especially during periods of time, permitting stabilization with adequate energy intake. (elastizell.com)

Palmer says this new version would help with dosing problems, as well as patients who might not be fit for an IV. (healthline.com)
Coadministration with venetoclax is contraindicated in patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) during the dose initiation and ramp-up phase of venetoclax. (guidelinecentral.com)
Patients' characteristics included catecholamine and sedative doses, the original angle of head of bed elevation (HBE), the level of positive end expiratory pressure (PEEP), duration and mode of mechanical ventilation. (biomedcentral.com)
This scale helps doctors prescribe safe doses of specific drugs to their patients that won't trigger an overdose. (serenityatsummit.com)

If ejection has not yet taken place but the pregnancy is not progressing, another dose of mifepristone together with misoprostol 800 mcg buccal might be administered. (emedz.net)

The contraction frequency did not change significantly among the 3 tested doses. (medsci.org)
The estimated ED90 of ropivacaine was 11.8 mg (95% CI 11.7-12.7) with and 14.7 mg (95% CI 14.6-16.0) without intravenous S-ketamine using biased coin up-down sequential dose-finding method, and the incidences of hypotension and its related symptoms were significantly lower in S-ketamine group. (researchsquare.com)

When itraconazole was administered intravenously to anesthetized dogs, a dose-related negative inotropic effect was documented. (druginteractionchecker.com)

sufentanil, calcium/magnesium/potassium/sodium oxybates. (medscape.com)
CLEVIPREX® (Clevidipine): A fast-acting, ultra-short half-life dihydropyridine calcium channel blocker used to rapidly reduce systolic blood pressure within two minutes of initial dosing. (asda.org)

apalutamide will decrease the level or effect of sufentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)

The patient was closely monitored to assure no blood pressure change with each dose since hypotension would cause devastating changes in the coronary perfusion pressures. (ispub.com)

this dose may be increased to whatever level is clinically necessary (900 mg is the daily maximum). (emedz.net)
However, the dose can be increased to a maximum of 600 mg once daily if clinically necessary. (emedz.net)
Table 3 includes clinically significant drug interactions with Sufentanil Citrate Injection. (pfizermedicalinformation.com)

Multivariable modeling revealed that mode and duration of mechanical ventilation, the norepinephrine dose, and HBE had statistically significant influences. (biomedcentral.com)

The Baxter InfusOR Features Drug specific SMART LABELS that help minimize the potential for medication errors in dose programming. (gtsmedical.com)
This is because drug exposure is greater with the Oral Solution than with the Capsules when the same dose of drug is given. (druginteractionchecker.com)

Participants will receive placebo or 40-160 mg total of oxycodone DETERx per day, divided into two doses. (hcplive.com)

Ananth J. Abstinence Syndrome from Therapeutic Doses of Oxazepam. (benzo.org.uk)
High sensitivity is required to detect these compounds following exposure because of the low dose required for therapeutic effect and the rapid clearance from the body for these compounds. (cdc.gov)

In these cases, your doctor may want to change the dose, or other precautions may be necessary. (mayoclinic.org)

I do TIVA for neuromonitoring combined with bolus fentanyl or sufentanil or a continuous sufentanil drip. (studentdoctor.net)

Participants will "start at 600mg and titrate up by 600mg a week for two weeks (to 1800mg), then remain on 1800mg steady state dose of medication (or placebo pills) for 2 weeks. (hcplive.com)

bremelanotide will decrease the level or effect of sufentanil by Other (see comment). (medscape.com)

Decrease eluxadoline dose to 75 mg PO BID if coadministered with OATP1B1 inhibitors. (medscape.com)

To reduce the risk of psychomimetic reactions, S-ketamine administration was limited to an ultra-low single dose in the present study. (researchsquare.com)
Explore An ADHD TreatmentDiscover an ADHD Treatment For Adults And Find Dosing &Administration Options Here. (collectingbanter.com)

If the upper sensory level of the patient reached T6 and the visual analogue scale (VAS) scores continuously below 3 before delivery, the next patient had a 1/9th chance of receiving a lower dose or an 8/9th chance of receiving the same of previous dose. (researchsquare.com)

Reduce the dose to 900 mg once daily if it is now 1,200 mg/day. (emedz.net)

Anatomy1

Diseases2

Chemicals and Drugs13

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Phenomena and Processes2

Health Care2

Anesthesia11

Bupivacaine14

Morphine11

Propofol5

Epidural2

Analgesia3

Analgesic2

Bolus dose1

Intraoperative2

Opioid3

Postoperative2

DSUVIA2

Opioids2

Daily dose3

Cesarean1

Single intravenous1

Overdoses2

Toxicity1

Patients4

Mifepristone1

Significantly2

Intravenously1

Calcium2

Intestinal1

Coronary1

Clinically3

Duration of mechanical ventilation1

Drug2

Oxycodone1

Therapeutic2

PRECAUTIONS1

Continuous1

Medication1

Effect1

Decrease1

Administration2

Lower dose1

Reduce1