BenzamidesPiperazinesPyrimidinesLeukemia, Myelogenous, Chronic, BCR-ABL PositiveGastrointestinal Stromal TumorsFusion Proteins, bcr-ablAntineoplastic AgentsProto-Oncogene Proteins c-kitProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor alphaLeukemia, Myeloid, Chronic-PhaseReceptor, Platelet-Derived Growth Factor betaBlast CrisisDrug Resistance, NeoplasmGenes, ablHypereosinophilic SyndromeCytogenetic AnalysisProto-Oncogene Proteins c-ablProtein-Tyrosine KinasesHypopigmentationK562 CellsGastrointestinal NeoplasmsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativePhiladelphia ChromosomeTreatment OutcomeRemission InductionReceptors, Platelet-Derived Growth FactorDermatofibrosarcomaMastocytosis, SystemicDrug ApprovalEnzyme InhibitorsPregnatrienesCell Line, TumorThiazolesFibromatosis, AggressiveDose-Response Relationship, DrugProto-Oncogene Proteins c-sisDisease-Free SurvivalHarringtoninesLeukemia, Myeloid, Accelerated PhaseAdministration, OralApoptosisCell ProliferationInterferon-alphaLichenoid EruptionsTime FactorsDrug Administration SchedulemRNA Cleavage and Polyadenylation FactorsDrug SynergismPhosphorylationNeoplasm, ResidualMutationAntineoplastic Combined Chemotherapy ProtocolsKetonesSurvival AnalysisPyrrolesFuransGene Expression Regulation, LeukemicCytogeneticsPrognosisTreatment FailureUnited States Food and Drug AdministrationRifabutinSalvage TherapyDisease ProgressionPrimary MyelofibrosisChromosomes, Human, Pair 9Survival RateReverse Transcriptase Polymerase Chain ReactionHydroxyureaIn Situ Hybridization, FluorescenceNeoplastic Stem CellsSTAT5 Transcription FactorPlatelet-Derived Growth FactorRecurrenceScleroderma, SystemicPrecursor Cell Lymphoblastic Leukemia-LymphomaStem Cell FactorHistiocytoma, Malignant FibrousInhibitory Concentration 50Follow-Up StudiesSignal TransductionRNA, MessengerMyeloid Progenitor CellsIndolesCell SurvivalFibrosisCombined Modality TherapyBlood Cell CountNeoadjuvant TherapyImmunohistochemistryGraves OphthalmopathyOncogene Proteins, FusionCells, CulturedAntigens, CD34Bone MarrowTransplantation, HomologousMilk ProteinsBlotting, WesternOrbit