• Do not change the settings on the infusion pump since you might get the wrong dose. (webmd.com)
  • National Institutes of Health researchers found that a single, low-dose ketamine infusion was relatively free of side effects for patients with treatment-resistant depression. (nih.gov)
  • Studies have shown that a single, subanesthetic-dose (a lower dose than would cause anesthesia) ketamine infusion can often rapidly relieve depressive symptoms within hours in people who have not responded to conventional antidepressants, which typically take weeks or months to work. (nih.gov)
  • The patients continued to receive prednisone (mean daily dose, 25 mg) and were randomly assigned to receive one infusion of immune globulin (2 g per kilogram of body weight) or placebo per month for three months, with the option of crossing over to the alternative therapy for three more months. (nih.gov)
  • IV injections are given either as a 1-to-2-min-bolus or an infusion with a longer duration to facilitate administering precise doses in a controlled manner or in providing a rapid response. (pharmtech.com)
  • A high-dose continuous infusion of IV dexmedetomidine was administered, and his violent behavior and delirium significantly improved. (hindawi.com)
  • To obtain vitamin C at pro-oxidant levels, at which it destroys cancer cells, is only achievable by intravenous infusion. (canceractive.com)
  • PROTOPAM Chloride for intravenous injection or infusion is prepared by cryo-desiccation. (nih.gov)
  • Some evidence suggests that a loading dose followed by continuous intravenous infusion of pralidoxime chloride may maintain therapeutic levels longer than short intermittent infusion therapy. (nih.gov)
  • In a cross-over study of seven healthy adults (18 - 50 years) a short intravenous infusion dose of 16 mg/kg over 30 minutes was compared to an intravenous loading dose of 4 mg/kg over 15 minutes, followed by 3.2 mg/kg/hr for 3.75 hours (for a total dose of 16 mg/kg). (nih.gov)
  • Results showed that the mean time over which plasma levels were maintained above 4 µg/mL was prolonged in the volunteers who received a loading dose followed by continuous infusion as compared to those who received short infusion therapy (257.5 ± 50.5 min vs. 118.0 ± 52.1 min). (nih.gov)
  • Use of continuous intravenous infusion in adult patients with organophosphate poisoning has been described in several case reports, with and without loading doses. (nih.gov)
  • Serious neurological toxicity (including irreversible paraparesis and quadraparesis) has been reported in patients who received LEUSTATIN Injection by continuous infusion at high doses (4 to 9 times the recommended dose for Hairy Cell Leukemia). (nih.gov)
  • LEUSTATIN (cladribine) Injection (also commonly known as 2-chloro-2΄-deoxy- β -D-adenosine) is a synthetic antineoplastic agent for continuous intravenous infusion. (nih.gov)
  • In a clinical investigation, 17 patients with Hairy Cell Leukemia and normal renal function were treated for 7 days with the recommended treatment regimen of LEUSTATIN Injection (0.09 mg/kg/day) by continuous intravenous infusion. (nih.gov)
  • These differences in dose-response relationships may reflect the involvement of multiple systems in controlling neuroendocrine, biochemical, and subjective responses to APZ infusion. (uaeu.ac.ae)
  • Nearly five months ago, a 30 year old woman named Jade Erick suffered a cardiac arrest , most likely due to anaphylactic shock, during the infusion of intravenous curcumin ordered by a California naturopath named Kim Kelly, ND (for Not-a-Doctor). (scienceblogs.com)
  • Our Octaplas, Pooled Plasma (human), Solvent/Detergent Treated Solution for Intravenous Infusion Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • This requires intravenous infusions of 75 grams of vitamin C, (in some cases less, depending on the size of the patient and the tumour cell mass), infused intravenously on a daily basis for three weeks in order to be able to attain these plasma levels. (canceractive.com)
  • The infusions are given over a period of an hour and a half to 3 and a half hours depending on the dose. (lotusrainclinic.com)
  • Three doses of APZ (0.003, 0.007, and 0.02 mg/kg) were administered to each subject in a random order with at least 4 days between infusions. (uaeu.ac.ae)
  • Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. (ox.ac.uk)
  • Patients receiving placebo infusions plus suboptimal low-dose MTX continued to have active disease, with a Paulus response lasting a median of 0 weeks. (ox.ac.uk)
  • CONCLUSION: Multiple infusions of cA2 were effective and well tolerated, with the best results occurring at 3 and 10 mg/kg either alone or in combination with MTX in approximately 60% of patients with active RA despite therapy with low-dose MTX. (ox.ac.uk)
  • Pharmacokinetics of cefepime was determined following single dose intravenous (IV) and intramuscular (IM) administration at the rate of 10 mg/kg body weight in a crossover design with an interval of 21 days between IV and IM injections. (tubitak.gov.tr)
  • Intramuscular or subcutaneous injection may be used when intravenous injection is not feasible. (nih.gov)
  • Dexamethasone phosphate/DEMO is recommended for systemic administration by intravenous or intramuscular injection when oral therapy is not feasible or desirable in the following conditions. (who.int)
  • CECT of the Head: 30 to 60 gI by intravenous injection. (drugs.com)
  • AIM: To compare the pharmacodynamic effect of an oral loading dose of 'noncoated' ASA 300 mg vs. an intravenous bolus injection of lysine acetylsalicylate 150 mg in patients with STEMI undergoing pPCI. (unipv.it)
  • CONCLUSION: In patients with STEMI undergoing pPCI the rate of nonresponsiveness to ASA was not different comparing an oral 'noncoated' loading dose of ASA with an intravenous bolus injection of lysine acetylsalicylate. (unipv.it)
  • An increase in heart rate of about 35 beats/minute (which is usually not noticed by the recipient) within 3-5 minutes of an I.V. dose, and a maximal increase in heart rate of about 35-45 beats/minute with I.M. or autoinjector administration, respectively, within about 35-45 minutes (the longer being with I.M. injection). (cdc.gov)
  • It is advisable to use an adequate test dose, possibly in combination with adrenaline, in order to promptly avoid accidental intravenous or intrathecal injection. (janusinfo.se)
  • Using a recombinant DNA-derived hyaluronidase enzyme is an approach for possibly changing dosing regimens and bioavailability of several types of agents, including biologics. (pharmtech.com)
  • To perform a cost-identification and cost-effectiveness analysis comparing oral corticosteroids (OCS) with high-dose intermittent intravenous corticosteroid (IVCS) regimens in the treatment of juvenile dermatomyositis (JDM). (northwestern.edu)
  • however, severe neurological toxicity has been reported rarely following treatment with standard cladribine dosing regimens. (nih.gov)
  • Acute nephrotoxicity has been observed with high doses of LEUSTATIN (4 to 9 times the recommended dose for Hairy Cell Leukemia), especially when given concomitantly with other nephrotoxic agents/therapies. (nih.gov)
  • Low- versus Standard-Dose Intravenous Alteplase in the Context of Bridging Therapy for Acute Ischemic Stroke: A Korean ENCHANTED Study. (le.ac.uk)
  • BACKGROUND AND PURPOSE: Following the positive results from recent trials on endovascular therapy (EVT), bridging therapy (intravenous alteplase plus EVT) is increasingly being used for the treatment of acute ischemic stroke. (le.ac.uk)
  • Higher doses of anti-D were clearly associated with a greater therapeutic response in the platelet count, with no increase in hemolysis for both acute and chronic ITP. (psu.edu)
  • Furthermore, for both acute and chronic ITP there was no relationship between the decrease in hemoglobin and the dose given (P = .22), nor between the increase in platelet count and fall in hemoglobin (P = .27). (psu.edu)
  • Studies on humans indicate that intravenous Vitamin C can be administered safely with relatively few adverse effects and with improved patient well-being an quality of life, and decrease in markers of inflammation and tumor growth. (lotusrainclinic.com)
  • While it is acknowledged that intravenous Vitamin C is not 'Standard Medicine' nor is it considered a form of 'evidenced based medicine', i t is widely used as an adjunctive therapy in the treatment of many of t he chronic degenerative diseases including c ancer. (drstewartsclinic.com)
  • However, the optimal dose of intravenous alteplase remains unknown in centers where bridging therapy is actively performed. (le.ac.uk)
  • The optimal dose for eventual recanalization and positive clinical outcomes in patients receiving bridging therapy also remains unknown. (le.ac.uk)
  • CONCLUSIONS: There was no difference in functional outcome between the patients receiving different doses of alteplase in centers actively performing bridging therapy. (le.ac.uk)
  • Samples for blood and synovial fluid cultures were obtained and anti-microbial therapy with intravenous cefuroxime was started. (cdc.gov)
  • Prolonged antalgic therapy usually uses doses that vary from 0.25 to 1 mg/kg of body weight. (janusinfo.se)
  • Background and objectives: Treatment of severe dermatological autoimmune diseases and toxic epidermal necrolysis (TEN) with high‐dose intravenous immunoglobulin (IVIg) is a well‐established procedure in dermatology. (cardiff.ac.uk)
  • We nistration of intravenous immunoglobulin undertook a retrospective review of the (IVIG) within the first 10 days of illness medical records of all cases with Kawasaki decreases the prevalence of coronary ar- disease referred, treated or discharged tery abnormalities (CAA) to 2%-5% [ 5-7 ]. (who.int)
  • Comprehensive assessment of side effects associated with a single dose of ketamine in treatment-resistant depression. (nih.gov)
  • Single Dose Pharmacokinetics of Cefepime after Intravenous and Intramu" by KALPESH PATANI, URVESH PATEL et al. (tubitak.gov.tr)
  • To reduce the risk of psychomimetic reactions, S-ketamine administration was limited to an ultra-low single dose in the present study. (researchsquare.com)
  • Single-dose intravenous tramadol for acu. (kocaeli.edu.tr)
  • Therapeutic agents can be introduced into the body by several routes of administration with each having specific advantages and disadvantages (see Table I). For many drugs, including biologics and anticancer agents, the traditional route of administration is intravenous (IV). (pharmtech.com)
  • Klein-Gitelman, MS , Waters, T & Pachman, LM 2000, ' The economic impact of intermittent high-dose intravenous versus oral corticosteroid treatment of juvenile dermatomyositis ', Arthritis Care and Research , vol. 13, no. 6, pp. 360-368. (northwestern.edu)
  • High dose vitamin C involves intravenous injections of vitamin C of up to 85 gm (depending upon body weight), every 5 days, for 8 rounds to increase 'Hydrogen Peroxide' levels in cells. (canceractive.com)
  • Intravenous vitamin C (IVC), vitamin C megadoses and cancer - a practical guide by Dr. Julian Kenyon of the Dove Clinic UK. (canceractive.com)
  • More correctly, High Dose vitamin C uses injections of ascorbate, and this acts as a pro-drug to increase H 2 O 2 in cancer cells and kill them. (canceractive.com)
  • They have conducted clinical research showing High dose vitamin C, delivered by the use of Intravenous vitamin C injections, significantly slows the rate of growth of cancer - either on its own, or in conjunction with chemotherapy and radiotherapy. (canceractive.com)
  • CW: So is intravenous vitamin C really an 'alternative' to conventional chemotherapy? (canceractive.com)
  • High dose intravenous vitamin C is one of these treatments, and we use it extensively in our clinic. (canceractive.com)
  • Consist of varying high doses of vitamin C , depending on the objective of the treatment. (lotusrainclinic.com)
  • Growing evidence is showing the benefit of High Dose Vitamin C in cancer patients - in enhancing quality of life, slowing tumor growth and synergistically enhancing the pro-oxidative properties of some conventional treatments, such as chemotherapy and radiation. (lotusrainclinic.com)
  • This pro-oxidant effect is via the action of hydrogen peroxide (H2O2) which is produced when pharmacological (very high) doses of vitamin C are given and vitamin C in the extracellular space reaches a specific concentration. (lotusrainclinic.com)
  • In addition large oral doses of vitamin C can lead to cramps, flatulence and diarrhea, However IV administration of vitamin C can bypass this tight control resulting in significantly higher plasma levels than are obtained through oral intake. (lotusrainclinic.com)
  • At these doses, peak plasma vitamin C concentrations can exceed 20 milliMoles or reach the plasma concentration of 400 mg/dL. (lotusrainclinic.com)
  • High doses of vitamin C have also been found to reduce biomarkers of inflammation, such as C-reactive protein (CRP), tumor necrosis factor (TNF-α), interferon-γ (IFN-γ), and the interleukins IL-1, IL2, IL-6, IL-8, in cancer patients. (lotusrainclinic.com)
  • The benefits of High Dose Intravenous Vitamin C are widely known in a variety of conditions. (drstewartsclinic.com)
  • Patients with the rare inherited disorder G6PD Deficiency cannot be treated with High Dose IV Vitamin C above 25 grams(25,000 mgs). (drstewartsclinic.com)
  • All patients who require High Dose Vitamin C above this level are tested beforehand for this rare condition at Dr Stewarts Clinic. (drstewartsclinic.com)
  • A typical intravenous Vitamin C treatment can go from 25 grams to 125 grams. (drstewartsclinic.com)
  • High-dose vitamin C may suppress these immune system effectors. (souforum.com)
  • As intravenous high-dose vitamin C treatment is known to be safe, this suggests that intravenous high-dose vitamin C may be the treatment of choice in the early stages of COVID-19. (souforum.com)
  • Cheng, Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)? (c19early.org)
  • It's also been found that intravenous curcumin in combination with vitamin C and glutathione (I call it the "Mother of All Antioxidants") has a potentiating effecting in helping people with chronic health conditions e.g. hepatitis C, liver fibrosis. (scienceblogs.com)
  • The purpose of the study was to determine the optimal dose of spinal ropivacaine for cesarean section with or without intravenous single bolus of S-ketamine and to observe the incidences of hypotension of both methods. (researchsquare.com)
  • If the patient had VAS scores above 2 or needed an extra epidural rescue bolus before delivery, a higher dose was used for the next patient. (researchsquare.com)
  • A spinal dose of ropivacaine 12 mg with single intravenous 0.15 mg/kg bolus dose of S-ketamine may significantly reduce the risk of hypotension and provide sedative status before delivery, thus the method could be cautiously used in parturients with high risks of hypotension or extreme nervousness. (researchsquare.com)
  • High-dose intravenous immune globulin is a safe and effective treatment for refractory dermatomyositis. (nih.gov)
  • vaccinia immune globulin intravenous, axicabtagene ciloleucel. (medscape.com)
  • vaccinia immune globulin intravenous, brexucabtagene autoleucel. (medscape.com)
  • vaccinia immune globulin intravenous, idecabtagene vicleucel. (medscape.com)
  • vaccinia immune globulin intravenous, lisocabtagene maraleucel. (medscape.com)
  • A search of the current literature found no studies examining the efficacy of intravenous tramadol on migraine pain. (kocaeli.edu.tr)
  • Intravenous administration. (pharmtech.com)
  • and a single gavage administration (nominal dose of 200 mg/kg in corn oil) to pregnant and lactating rats. (rti.org)
  • Scanning may be performed immediately after completion of the intravenous administration. (drugs.com)
  • The US Food and Drug Administration (FDA) has approved an intravenous (IV) formulation of secukinumab (Cosentyx) for the treatment of adults with psoriatic arthritis (PsA), ankylosing spondylitis (AS), and nonradiographic axial spondyloarthritis (nr-axSpA). (medscape.com)
  • Cladribine plasma concentration after intravenous administration declines multi-exponentially with an average half-life of 6.7 +/- 2.5 hours. (nih.gov)
  • Neuroendocrine, biochemical, cardiovascular, and behavioral parameters were assessed in seven normal volunteers for 2 h after intravenous administration of alprazolam (APZ). (uaeu.ac.ae)
  • A significant correlation was found between dose and peak increase in platelet count measured in the 14 days following administration. (psu.edu)
  • Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration. (cdc.gov)
  • in a broad sense, the safe dose that should not be exceeded both for adults and for children is 2 mg/kg for each administration. (janusinfo.se)
  • Description: This is a dose level table that contains all vaccinia vaccine doses (including monkeypox) reported to the California Immunization Registry (CAIR2) and the Healthy Futures Registry (the San Diego Immunization Registry was integrated into CAIR2 in April 2022). (ca.gov)
  • drugs containing calcium injected in the same intravenous line. (rxlist.com)
  • This report summarizes the clinical course of 17 patients with non-Hodgkin's lymphomas who were treated with high dose intermittent intravenous cyclophosphamide between 1966 and 1968. (karger.com)
  • High dose cyclophosphamide alone may provide long term control of some patients with nodular lymphomas. (karger.com)
  • Type of cholinesterase inhibitor toxicity that may require extremely high doses of atropine. (cdc.gov)
  • The safety, tolerability, and nontoxicity of curcumin at high doses have been well established by human clinical trials. (scienceblogs.com)
  • Adjunctive treatment where high pharmacological doses are needed. (who.int)
  • Intravenous high dose penicillin treatment, for five weeks, was started in combination with gentamicin, for the first 10 days. (cdc.gov)
  • IV dosing requires the skilled insertion of a needle or catheter directly into a vein, a process that can be challenging, especially in certain patient types such as obese, palliative-care, and neonate patients. (pharmtech.com)
  • The dose of this medicine will be different for different patients. (mayoclinic.org)
  • The primary end point was the different rate of patients with ARU more than 550 at 2 h after the loading dose of oral vs. intravenous ASA. (unipv.it)
  • RESULTS: The study was planned with a sample size of 68 patients, but it was prematurely stopped due to slow enrollment after the inclusion of 23 patients, 12 randomized to oral ASA and 11 to intravenous lysine acetylsalicylate. (unipv.it)
  • 2002) Thus, even when given sufficient doses of atropine, patients may need artificial ventilation, sometimes for weeks. (cdc.gov)
  • Remicade, Centocor, Malvern, PA) given alone or in combination with low-dose methotrexate (MTX) in rheumatoid arthritis (RA) patients. (ox.ac.uk)
  • METHODS: In a 26-week, double-blind, placebo-controlled, multicenter trial, 101 patients with active RA exhibiting an incomplete response or flare of disease activity while receiving low-dose MTX were randomized to 1 of 7 groups of 14-15 patients each. (ox.ac.uk)
  • The patients received either intravenous cA2 at 1, 3, or 10 mg/kg, with or without MTX 7.5 mg/week, or intravenous placebo plus MTX 7.5 mg/week at weeks 0, 2, 6, 10, and 14 and were followed up through week 26. (ox.ac.uk)
  • For patients who are unable to take the oral formulations, the recommended intravenous dose is 1 mg per kg infused over 1 hour every 4 hours. (drugs.com)
  • Pediatric patients (aged 4 weeks to less than 18 years): Dosage should be calculated based on body weight not to exceed adult dose. (drugs.com)
  • Patients requiring intravenous antibiotics during the first 6 months had lower IgG levels at 6 months (p= 0.004). (lu.se)
  • The risk of hypogammaglobulinemia in these patients increases with age and higher glucocorticoid doses. (lu.se)
  • 2 patients needed a second dose of IVIG, and 1 patient required a third. (who.int)
  • 2 patients ont eu besoin d'une seconde dose d'immunoglobuline intraveineuse et un patient a eu besoin d'une troisième dose. (who.int)
  • In pregnant rats, the concentrations of both radioactivity and SAN Trimer 2 h after dosing were highest in the blood, followed by the placenta, with the lowest levels in the fetus. (rti.org)
  • It is, however, necessary, to use the lowest doses and concentrations that can allow to obtain the sought for effect. (janusinfo.se)
  • However, widespread off-label use of intravenous subanesthetic-dose ketamine for treatment-resistant depression has raised concerns about side effects, especially given its history as a drug of abuse. (nih.gov)
  • For whatever reason, however she found him, she sought out treatment from a naturopath named Kim Kelly, who, as it turns out, has been a vocal advocate of intravenous curcumin to treat…just about everything. (scienceblogs.com)
  • METHODS: In this prospective Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED) sub-study, we explored the outcomes following treatment with two different doses (low- [0.6 mg/kg] or standard-dose [0.9 mg/kg]) of intravenous alteplase across 12 Korean centers where EVT is actively performed. (le.ac.uk)
  • Children exposed to the same levels of malathion as adults may receive a larger dose because they have greater lung surface area:body weight ratios and higher minute volume:weight ratios. (cdc.gov)
  • Methods such as intrathecal adjuvant opioid use to reduce the total dose of anaesthetics delivered, 8 prophylactic use of vasopressors, 4,9 and the use of intravenous (IV) pre-load colloid liquid 10 have been proposed to reduce the incidence or extent of maternal hypotension after spinal anesthesia during cesarean delivery. (researchsquare.com)
  • The twice-weekly dose of RFB (300mg) remains unchanged if the patient is also taking these protease inhibitors. (cdc.gov)
  • or or A 20%-25% increase in the dose of protease inhibitors or NNRTIs might be necessary. (cdc.gov)
  • INH Daily for 2 weeks and INH 2 times/week for The patient should be monitored If the patient also is taking RFB then 2 times/week for RFB 4 months (18 weeks) carefully for RFB drug toxicity efavirenz, the daily or twice (arthalgia, uveitis,leukopenia) weekly dose of RFB is increased if RFB is used concurrently from 300mg to 450 mg. with protease inhibitors or NNRTIs. (cdc.gov)
  • Depending on how severe your hand-foot syndrome is, your doctor may give you something to reduce the symptoms, or decrease or delay your next dose of liposomal doxorubicin . (webmd.com)
  • Mild cases may be treated with oral doxycycline, while severe cases are usually treated with intravenous oxytetracycline. (wikipedia.org)
  • Severe adverse events (SAEs) were defined as episodes requiring hospitalization or intravenous antibiotics, malignancies, or death. (lu.se)
  • It has been suggested that when these physiological changes do not occur with this dose (sometimes referred to as an atropine challenge ), this is indicative of cholinesterase inhibitor toxicity. (cdc.gov)
  • One author suggest avoiding large doses of pre-mixed atropine containing alcohol preservatives in children out of concern that alcohol toxicity could complicate the situation. (cdc.gov)
  • Cite this: FDA Approves Intravenous Formulation of Secukinumab - Medscape - Oct 09, 2023. (medscape.com)
  • If the upper sensory level of the patient reached T6 and the visual analogue scale (VAS) scores continuously below 3 before delivery, the next patient had a 1/9th chance of receiving a lower dose or an 8/9th chance of receiving the same of previous dose. (researchsquare.com)
  • The optimal dose of APZ needed to produce a neuroendocrine or behavioral change appears to differ depending on the parameter of interest. (uaeu.ac.ae)
  • From 1980 to 1986 Dr. Sprague studied and practiced all aspects of environmental medicine at a prominent clinic in Dallas, Texas, including alternative Low Dose Allergy treatments, which he continues to offer today. (aaemonline.org)
  • SAN Trimer was rapidly eliminated from blood (T1/2 1 h) following a single intravenous dose and following single oral doses (T1/2 3-4 h). (rti.org)
  • SAN Trimer was also rapidly excreted in the urine and feces following single oral doses, while total radioactivity was cleared more slowly. (rti.org)
  • List Ceftazidime Solution, Intravenous Piggyback side effects by likelihood and severity. (webmd.com)
  • Derived from value recorded for second dose, unless null, then first dose value is used. (ca.gov)
  • To overcome the limitations associated with side effects and intravenous delivery, ongoing research efforts seek to develop a more practical rapid-acting antidepressant that works in the brain similarly to ketamine. (nih.gov)
  • The 90% effective dose (ED90) and 95% confidence interval (95% CI) were estimated by isotonic regression. (researchsquare.com)