Dose escalation study of melphalan hydrochloride. Medical search. Frequent questions

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Anatomy6

Organs at Risk Bone Marrow Urogenital System Extremities Rectum Liver

Organisms2

Rats, Nude Rats, Sprague-Dawley

Diseases47

Neoplasms Lung Neoplasms Multiple Myeloma Neutropenia Stomatitis Thrombocytopenia Hematologic Diseases Nausea Radiation Injuries Leukopenia Neoplasm Recurrence, Local Recurrence Amyloidosis Vomiting Brain Neoplasms Melanoma Neoplasm Metastasis Prostatic Neoplasms Sarcoma Carcinoma, Non-Small-Cell Lung Radiation Pneumonitis Disease Progression Asthenia Neuroleptic Malignant Syndrome Fatigue Lymphoma, Non-Hodgkin Breast Neoplasms Acneiform Eruptions Ovarian Neoplasms Supratentorial Neoplasms Exanthema Adenocarcinoma Neuroblastoma Hematologic Neoplasms Diarrhea Hodgkin Disease Liver Neoplasms Head and Neck Neoplasms Gastrointestinal Stromal Tumors Carcinoma Bone Neoplasms Esophagitis Headache Neoplasms, Experimental Glioma Leukemia, Myeloid, Acute Sarcoma, Experimental

Chemicals and Drugs98

Melphalan Antineoplastic Agents Carboplatin Rhenium Antibodies, Monoclonal Antineoplastic Agents, Alkylating Cyclophosphamide Carmustine Guanidine Pyrazolones Doxorubicin Etoposide Paclitaxel Thalidomide Myeloablative Agonists Trimethylsilyl Compounds Boronic Acids Pyrazines Prednisone Granulocyte Colony-Stimulating Factor Cisplatin Antineoplastic Agents, Phytogenic Nitrogen Mustard Compounds Camptothecin Vincristine Topotecan Deoxycytidine Benzamides Fluorouracil Piperazines Pyrimidines Guanidines Antimetabolites, Antineoplastic Thiotepa Misonidazole Recombinant Proteins Cytarabine Vinblastine Taxoids Buthionine Sulfoximine Ifosfamide Methionine Sulfoximine Antibodies, Monoclonal, Humanized Thiosemicarbazones Tablets Alkylating Agents Organoplatinum Compounds Busulfan Quinazolines Pyrazoles Iodine Radioisotopes Anthraquinones Chlorambucil Protein Kinase Inhibitors Mitoxantrone Dacarbazine Methotrexate Immunotoxins Radioisotopes Pyridines Epirubicin Prodrugs Tumor Necrosis Factor-alpha Angiogenesis Inhibitors Indoles Radiation-Sensitizing Agents Dexamethasone Phenylurea Compounds Paroxetine Antirheumatic Agents Antidepressive Agents, Second-Generation Semustine Nitroimidazoles Niacinamide Lomustine Radiopharmaceuticals Anticonvulsants Antibiotics, Antineoplastic Immunosuppressive Agents Leucovorin Cocaine Drug Combinations Heroin Vidarabine Delayed-Action Preparations Sulfonamides Alfaxalone Alfadolone Mixture Enzyme Inhibitors Dosage Forms Flunarizine Tilorone Glutathione Granulocyte-Macrophage Colony-Stimulating Factor Quinolines Food Additives Piperidines Phenethylamines Histamine Agents

Analytical, Diagnostic and Therapeutic Techniques and Equipment76

Maximum Tolerated Dose Area Under Curve Drug Administration Schedule Treatment Outcome Antineoplastic Combined Chemotherapy Protocols Radiotherapy Dosage Infusions, Intravenous Dose-Response Relationship, Radiation Administration, Oral Combined Modality Therapy Double-Blind Method Cohort Studies Chemotherapy, Cancer, Regional Perfusion Feasibility Studies Drug Evaluation Radiotherapy, Conformal Dose Fractionation Radiotherapy, Intensity-Modulated Clinical Trials, Phase I as Topic Radiotherapy Planning, Computer-Assisted Transplantation, Autologous Metabolic Clearance Rate Hematopoietic Stem Cell Transplantation Radiation Dosage Radiometry Disease-Free Survival Remission Induction Survival Analysis Drug Therapy, Combination Injections, Intravenous Salvage Therapy Transplantation Conditioning Follow-Up Studies Survival Rate Radiotherapy, Image-Guided Drug Dosage Calculations Self Administration Bone Marrow Transplantation Neoplasm Staging Clinical Trials as Topic Lymphatic Irradiation Radioimmunotherapy Radiotherapy, Computer-Assisted Prospective Studies Radiotherapy Retrospective Studies Chromatography, High Pressure Liquid Radiotherapy, High-Energy Proton Therapy Tumor Burden Prognosis Brachytherapy Protein Denaturation Chemoradiotherapy Leukocyte Count Four-Dimensional Computed Tomography Injections, Subcutaneous Pilot Projects Drug Screening Assays, Antitumor Injections, Intramuscular Stem Cell Transplantation Kaplan-Meier Estimate Whole-Body Irradiation Peripheral Blood Stem Cell Transplantation Lethal Dose 50 Infusions, Parenteral Hyperthermia, Induced Delayed-Action Preparations Positron-Emission Tomography Drug Stability Dosage Forms Radiosurgery Analysis of Variance Neoplasms, Experimental Tomography, X-Ray Computed Sarcoma, Experimental

Phenomena and Processes20

Maximum Tolerated Dose Dose-Response Relationship, Drug Area Under Curve Dose-Response Relationship, Radiation Time Factors Metabolic Clearance Rate Radiation Dosage Half-Life Drug Resistance Drug Resistance, Neoplasm Drug Synergism Drug Interactions Biological Availability Tissue Distribution Protein Denaturation Leukocyte Count Cell Survival Lethal Dose 50 Dose-Response Relationship, Immunologic Kinetics

Disciplines and Occupations1

Chemistry, Pharmaceutical

Technology, Industry, Agriculture1

Information Science5

Radiotherapy, Conformal Radiotherapy, Intensity-Modulated Radiotherapy Planning, Computer-Assisted Survival Rate Radiotherapy, Computer-Assisted

Health Care21

Area Under Curve Treatment Outcome Dose-Response Relationship, Radiation Double-Blind Method Cohort Studies Feasibility Studies Clinical Trials, Phase I as Topic Radiation Dosage Disease-Free Survival Survival Analysis Radiation Injuries Follow-Up Studies Survival Rate Relative Biological Effectiveness Clinical Trials as Topic Prospective Studies Retrospective Studies Safety Pilot Projects Kaplan-Meier Estimate Analysis of Variance

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Melphalan Maximum Tolerated Dose Dose-Response Relationship, Drug Area Under Curve Drug Administration Schedule Treatment Outcome Antineoplastic Combined Chemotherapy Protocols Radiotherapy Dosage Neoplasms Antineoplastic Agents Infusions, Intravenous Dose-Response Relationship, Radiation Carboplatin Administration, Oral Combined Modality Therapy Rhenium Antibodies, Monoclonal Double-Blind Method Lung Neoplasms Antineoplastic Agents, Alkylating Cohort Studies Chemotherapy, Cancer, Regional Perfusion Feasibility Studies Multiple Myeloma Drug Evaluation Radiotherapy, Conformal Dose Fractionation Radiotherapy, Intensity-Modulated Clinical Trials, Phase I as Topic Radiotherapy Planning, Computer-Assisted Transplantation, Autologous Neutropenia Cyclophosphamide Time Factors Carmustine Guanidine Pyrazolones Doxorubicin Organs at Risk Etoposide Paclitaxel Metabolic Clearance Rate Hematopoietic Stem Cell Transplantation Thalidomide Stomatitis Thrombocytopenia Myeloablative Agonists Trimethylsilyl Compounds Boronic Acids Pyrazines Prednisone Radiation Dosage Radiometry Disease-Free Survival Hematologic Diseases Granulocyte Colony-Stimulating Factor Remission Induction Nausea Survival Analysis Radiation Injuries Cisplatin Antineoplastic Agents, Phytogenic Nitrogen Mustard Compounds Camptothecin Vincristine Topotecan Leukopenia Half-Life Drug Therapy, Combination Injections, Intravenous Neoplasm Recurrence, Local Deoxycytidine Benzamides Salvage Therapy Transplantation Conditioning Follow-Up Studies Survival Rate Recurrence Amyloidosis Radiotherapy, Image-Guided Fluorouracil Drug Resistance Piperazines Pyrimidines Guanidines Relative Biological Effectiveness Vomiting Brain Neoplasms Drug Resistance, Neoplasm Melanoma Antimetabolites, Antineoplastic Thiotepa Neoplasm Metastasis Prostatic Neoplasms Misonidazole Drug Dosage Calculations Self Administration Bone Marrow Transplantation Sarcoma Recombinant Proteins

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