• Twice daily doses of 200mg of cimetidine will suffice to provide steady IC50 levels (concentration producing 50% inhibition) for HIV replication. (i-sis.org.uk)
  • Viagra, the 100mg and 200mg doses can. (njacs.org)
  • 6-8 Although patients taking approved doses of loperamide for a short episode of diarrhea are unlikely to suffer adverse reactions from these interactions, patients taking excess doses are at much greater risk for adverse events. (pharmacytimes.com)
  • Fluvoxamine , ketoconazole , and cimetidine may increase the levels of Remeron in the blood which may lead to increased side effects from Remeron. (medicinenet.com)
  • The way propranolol works may be affected by cimetidine (for indigestion, stomach ulcers), fluvoxamine (for depression), and hydralazine (for high blood pressure). (theonlineclinic.co.uk)
  • Chloroquine and atovaquone-proguanil at doses used for malaria chemoprophylaxis can be given concurrently with oral typhoid vaccine. (cdc.gov)
  • Use of any therapeutic agents known to alter any major organ function (e.g., barbiturates, opiates, phenothiazines, cimetidine) within 30 days prior to dosing. (who.int)
  • In these cases, your doctor may want to change the dose, or other precautions may be necessary. (mayoclinic.org)
  • See the "Cimetidine Precautions" section. (rxwiki.com)
  • The recommended starting dose for ZOMIG nasal spray in adult and pediatric patients 12 years of age and older is 2.5 mg. (nih.gov)
  • Although there may be an increased potential for undesirable effects at higher doses, if after some weeks on the recommended dose insufficient response is seen, some patients may benefit from having their dose increased up to a maximum of 32 mg (16 drops) a day (see section 5.1). (medicines.org.uk)
  • Patients should be started on 8 mg (4 drops)/day and the dose gradually increased in 8 mg (4 drops) steps according to the patient's response up to the recommended dose. (medicines.org.uk)
  • For elderly patients the dose should be decreased to half of the recommended dose, e.g. 8mg (4 drops) to 16mg (8 drops) daily. (medicines.org.uk)
  • An initial dose of 8mg (4 drops) daily for the first two weeks of treatment is recommended in patients with mild or moderate hepatic impairment. (medicines.org.uk)
  • Caution and extra careful dose titration is advised in patients with severely reduced hepatic function (see section 5.2). (medicines.org.uk)
  • No dose adjustment is required for patients with creatinine clearance 20 ml/minute (see section 5.2). (who.int)
  • For patients on renal dialysis, an additional dose of [HA570 trade name] is recommended after each dialysis. (who.int)
  • No dose adjustment is necessary in patients with mild to moderate hepatic impairment (see sections 4.4 and 5.2). (who.int)
  • Table 4 enumerates adverse events that occurred at an incidence of 1% or more, and were more frequent than in the placebo group, among Remeron (mirtazapine) Tablets-treated patients who participated in short-term US placebo-controlled trials in which patients were dosed in a range of 5 to 60 mg/day. (medicinenet.com)
  • Lower initial doses of adenosine should be used in patients who are taking carbamazepine. (medscape.com)
  • Note: patients in the dose-finding portion of the study may have received other anti-neoplastic therapy after progression on alectinib. (dana-farber.org)
  • Since labetalol hydrochloride injection at the usual IV therapeutic doses has not been studied in patients with nonallergic bronchospastic disease, it should not be used in such patients. (druglib.com)
  • There is some anecdotal evidence suggesting that a small daily dose of 2mg of warfarin do not affect the "prothrombin-time", a lab test to monitor blood coagulation in HIV patients, but does significantly lower viral loads. (i-sis.org.uk)
  • A daily dose of warfarin appears to improve the fluency of speech and mental aptitude of patients suffering from progressive dementia associated with the full-blown AIDS disease. (i-sis.org.uk)
  • If there is insufficient relief of symptoms in such patients, the dose may be cautiously increased to 1200 mg, but only with close monitoring [see CLINICAL PHARMACOLOGY ]. (globalrph.com)
  • In some patients low doses of TCAs (75 - 100 mg daily) may be effective with less adverse effects than higher doses (bpac nz , 2004). (bpac.org.nz)
  • Patients on warfarin might need to reduce their anticoagulant dose or monitor their prothrombin time more closely while taking atovaquone-proguanil, although coadministration of these drugs is not contraindicated. (cdc.gov)
  • A. Sexual dysfunction has been reported in a small number of patients receiving therapeutic doses of venlafaxine. (antidepressantsfacts.com)
  • Single oral doses of labetalol HCl administered to patients with coronary artery disease had no significant effect on sinus rate, intraventricular conduction, or QRS duration. (guidelinecentral.com)
  • Doses of labetalol HCl that controlled hypertension did not affect renal function in mildly to severely hypertensive patients with normal renal function. (guidelinecentral.com)
  • Note: may need higher dose in patients with central nervous system disease. (cdc.gov)
  • Patients self-treating diarrhea and loperamide abusers report taking daily doses of 25 to more than 200 mg. (pharmacytimes.com)
  • Patients taking loperamide should be counseled to avoid taking more than the labeled dose. (pharmacytimes.com)
  • If usual doses of loperamide are not effective in relieving diarrhea, patients should be advised to see their health care provider. (pharmacytimes.com)
  • Patients should be screened prior to receipt of each vaccine dose, and those with a contraindication should not be vaccinated. (cdc.gov)
  • After 1 year of therapy, 2 of 3 patients showed considerable improvement when combined with low-dose corticosteroids. (medscape.com)
  • Cimetidine comes as a tablet and a liquid to take by mouth. (medlineplus.gov)
  • The tablet can be divided into equal doses. (who.int)
  • The recommended dose of [HA570 trade name] is one 200-mg tablet daily for the first 14 days (this lead-in period can lessen the frequency of rash), followed by one 200-mg tablet twice daily, in combination with at least two other antiretroviral medicines. (who.int)
  • When administering chewable tablets, at least two tablets should be administered to ensure adequate buffering capacity (e.g., if the child's dose is 50 mg, administer two 25-mg tablets and not one 50-mg tablet). (cdc.gov)
  • The GEMINI 1 & 2 phase III studies compared a 2DR of dolutegravir plus lamivudine to a 3-drug regimen of dolutegravir plus the fixed-dose tablet tenofovir/emtricitabine (TDF/FTC). (gsk.com)
  • The recommended dose of cimetidine to treat ulcers caused by anti-inflammatory medications is 800 mg daily, either as 400 mg taken twice a day or 800 mg taken at bedtime. (medbroadcast.com)
  • Inhibitors of hepatic microsomal enzymes, such as erythromycin, clarithromycin, and cimetidine, increase carbamazepine levels and may cause toxicity. (medscape.com)
  • Need for treatment during the first 7 days of the study with NSAIDs, Cyclooxygenase-2 (COX-2) inhibitors, acetyl salicylic acid (ASA) (including low dose) or clopidogrel. (astrazenecaclinicaltrials.com)
  • Live attenuated vaccines generally should be avoided in immunocompromised travelers, including those taking antimetabolites, calcineurin inhibitors, cytotoxic agents, immunomodulators, and high-dose steroids (see Table 3-04 ). (cdc.gov)
  • The combination of warfarin and cimeditine was previously thought to be incompatible, but there have been no reports of adverse reactions at low doses of cimetidine and 2mg of warfarin in more than a hundred available references in the TOXLINE database. (i-sis.org.uk)
  • Cimetidine is an over the counter ant-acid or anti-ulcer drug otherwise known as Tagamet, and as such inhibits gastric acid secretion via histamine type (H2) receptors on parietal cells (in the stomach. (i-sis.org.uk)
  • SSRIs, amiodarone, cimetidine, methadone) will increase plasma concentrations of TCAs and dose related adverse effects. (bpac.org.nz)
  • Cimetidine belongs to a group of drugs called Histamine H2 Receptor Antagonists. (rxwiki.com)
  • Travelers taking atovaquone-proguanil for malaria prophylaxis should avoid using cimetidine (an H2 receptor antagonist) because this medication interferes with proguanil metabolism. (cdc.gov)
  • The maximum recommended single dose of ZOMIG is 5 mg. (nih.gov)
  • A single dose of albendazole is sufficient to treat intestinal infestations by A. duodenale or Necator americanus . (wikipedia.org)
  • Peak plasma concentrations occur within 1-2 hours of oral administration of a single dose. (genelabs.com)
  • On the basis of mass balance studies, at least 92% of a single dose of venlafaxine is absorbed. (drugs.com)
  • No consensus on the treatment of eosinophilic fasciitis exists, but most studies indicate that the best response is with moderate-to-high doses of corticosteroids, especially if started early in the disease course. (medscape.com)
  • 60-69% of a single orally administered dose of amoxapine is excreted in urine, principally as conjugated metabolites. (genelabs.com)
  • A 1 mL/kg (20 mg/kg caffeine citrate providing 10 mg/kg as caffeine base) loading dose of caffeine citrate was administered intravenously, followed by a 0.25 mL/kg (5 mg/kg caffeine citrate providing 2.5 mg/kg of caffeine base) daily maintenance dose administered either intravenously or orally (generally through a feeding tube). (drugs.com)
  • Cimetidine is in a class of medications called H 2 blockers. (medlineplus.gov)
  • tell your doctor and pharmacist if you are allergic to cimetidine or any other medications. (medlineplus.gov)
  • Your doctor may need to change the doses of your medications or monitor you carefully for side effects. (medlineplus.gov)
  • Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. (medbroadcast.com)
  • Carbamazepine can interfere with the action of low-dose oral contraceptives and may lead to breakthrough vaginal bleeding, ovulation, and even pregnancy in women who are taking both medications. (medscape.com)
  • The half-life of routinely used medications and adjustment of the dose according to the perioperative schedule must be considered. (medscape.com)
  • Many medications must be continued through the perioperative period, with the last dose taken with a sip of clear liquid up to 2 hours prior to the procedure, and resumed during recovery. (medscape.com)
  • Because of the newer, easier to dose medications available such as cimetidine, aluminum magnesium hydroxide is not used as frequently for stomach ulcers and esophageal reflux. (dogfoodadvisor.com)
  • To treat gastroesophageal reflux disease (GERD), the recommended dose is 1,200 mg daily in divided doses. (medbroadcast.com)
  • Steady-state concentrations of both venlafaxine and ODV in plasma were attained within 3 days of multiple-dose therapy. (drugs.com)
  • Serum concentrations of caffeine should be monitored and dose administration of caffeine citrate should be adjusted to avoid toxicity in this population. (drugs.com)
  • The reported plasma concentrations following usual doses of loperamide range from 0.2 to 1.2 ng/mL. (pharmacytimes.com)
  • Loperamide has proved to be remarkably safe when used at recommended doses. (pharmacytimes.com)
  • Therefore, when a patient takes a 2-mg dose, only 0.006 mg of loperamide reaches systemic circulation. (pharmacytimes.com)
  • At these doses, the plasma loperamide concentration can exceed 100 ng/mL. 2 In addition to decreasing gut motility, these large doses can cause sedation, urinary retention, respiratory depression, cardiac arrhythmias, and death. (pharmacytimes.com)
  • The maximum daily dose should not exceed 10 mg in any 24‑hour period. (nih.gov)
  • Citalopram should be administered as a single oral dose of 16mg (8 drops) daily. (medicines.org.uk)
  • Dependent on individual patient response, the dose may be increased to a maximum of 32mg (16 drops) daily. (medicines.org.uk)
  • A single oral dose of 8mg (4 drops) is recommended for the first week before increasing the dose to 16mg (8 drops) daily. (medicines.org.uk)
  • The recommended maximum dose for the elderly is 16mg (8 drops) daily. (medicines.org.uk)
  • Dosage of Metaglip is individualized on the basis of both effectiveness and tolerance while not exceeding the maximum recommended daily dose of 20 mg glipizide/2000 mg metformin. (rxlist.com)
  • If a rash develops during the 14-day lead-in period with once-daily dosing then the dose of nevirapine should not be increased until the rash has resolved. (who.int)
  • If nevirapine is interrupted for longer than 7 days, it should be restarted with once-daily dosing and the dose increased after 14 days to the full, twice-daily regimen. (who.int)
  • When treating duodenal or gastric ulcers, the dose ranges from 800 mg to 1,200 mg daily, in divided doses. (medbroadcast.com)
  • To reduce the amount of stomach acid produced in conditions that cause over secretion, the dose should be started at 300 mg taken 4 times a day, but may be increased to control symptoms to a maximum of 2,400 mg daily. (medbroadcast.com)
  • An average PI (protease inhibitor) used in triple-drug treatments of HIV cost between $10-$20 per day, in contrast to a daily dose of 2 mg warfarin which costs as little as 10 cents. (i-sis.org.uk)
  • The maximum recommended total daily dose of DAYPRO in adults is 1800 mg (26 mg/kg, whichever is lower) in divided doses. (globalrph.com)
  • The daily dose can be increased by 10 - 25 mg every week. (bpac.org.nz)
  • The usual effective dose is 50 - 150 mg daily (median 50 - 75 mg daily) (Gilron, 2006). (bpac.org.nz)
  • Doses containing more than 400 mg of caffeine daily have been linked to side effects. (medlineplus.gov)
  • Pediatric dose: 4 mg per kg of body weight twice daily. (cdc.gov)
  • Range, aug 25, is considerably less expensive, another study at a 400 mg and 800 mg daily dose of fluconazole demonstrated that diflucan taken in doses of 400 mgday or greater significantly increases plasma levels of terfenadine when taken concomitantly. (ultimateunderground.com)
  • Propranolol should be stopped only when your doctor tells you and/or after talking to your doctor because you may need to stop it gradually by lowering the daily dose. (theonlineclinic.co.uk)
  • Plasma clearance, elimination half-life and steady-state volume of distribution were unaltered for both venlafaxine and ODV after multiple-dosing. (drugs.com)
  • Monitor for changes in the therapeutic and adverse effects of amoxapine if atazanavir if initiated, discontinued or dose changed. (genelabs.com)
  • In osteoarthritis and rheumatoid arthritis and juvenile rheumatoid arthritis, the dosage should be individualized to the lowest effective dose of DAYPRO to minimize adverse effects. (globalrph.com)
  • Cimetidine is also used to prevent ulcers in certain circumstances and to treat certain conditions that are associated with over secretion of acid by the stomach (i.e. (medbroadcast.com)
  • Cimetidine first came to the attention of Bourinbaiar and Jirathitikal when they observed the inhibition of human T cells leukaemia virus (HTLV-1) secretion from chronically infected cells. (i-sis.org.uk)
  • This led them to the idea that viral release is regulated in the same way as gastric acid secretion, and to discover that cimetidine has broad anti-retroviral activity. (i-sis.org.uk)
  • Pediatric usual dose: In combination with other antiretrovirals: 90 mg per m2 of body surface area every 12 hours. (cdc.gov)
  • Neonatal dose: Under evaluation in Pediatric AIDS Clinical Trial Group protocol 332. (cdc.gov)
  • Pediatric dose: 1 mg per kg of body weight every 12 hours (up to weight of 30 kg). (cdc.gov)
  • Labetalol HCl consistently, in dose-related fashion, blunted increases in exercise-induced blood pressure and heart rate, and in their double product. (guidelinecentral.com)
  • The pulmonary circulation during exercise was not affected by labetalol HCl dosing. (guidelinecentral.com)
  • Labetalol HCl produces dose-related falls in blood pressure without reflex tachycardia and without significant reduction in heart rate, presumably through a mixture of its alpha- and beta-blocking effects. (guidelinecentral.com)
  • Less than 5% of the dose is excreted as unchanged drug in urine. (genelabs.com)
  • Cimetidine was developed as part of a research effort led by Nobel laureate Sir James Black, and was the first H2-antagonist to receive approval from the FDA (Food and Drug Administration) in 1977. (i-sis.org.uk)
  • Switching to an alternative formulation of the same drug may involve a change in dose due to differing bioavailability of the active drug. (medscape.com)
  • A. A drug interaction may occur between cimetidine and venlafaxine resulting in a reduction of venlafaxine clearance and an increase in the peak serum concentration of venlafaxine. (antidepressantsfacts.com)
  • The long-acting, once-monthly, injectable regimen of cabotegravir and rilpivirine has the potential to give people living with HIV one month between doses with similar safety and efficacy as today's standard of care - an oral three-drug regimen that has to be taken every day. (viivhealthcare.com)
  • Cimetidine treats acid reflux, stomach ulcers, heartburn, and other digestion problems caused by too much stomach acid. (rxwiki.com)
  • Unusual (more severe): Peripheral neuropathy (dose related), electrolyte abnormalities, and hyperuricemia. (cdc.gov)
  • Non-severe, immediate (onset within 4 hours) allergic reaction after a previous dose of COVID-19 vaccine. (cdc.gov)
  • Bourinbair and Jirathitikal found that a combination of warfarin with anti-HIV compounds discovered by them, such as cimetidine and lavamisole seem to enhance the beneficial immune effect. (i-sis.org.uk)
  • A dose adjustment may be required when coadministering these compounds. (medscape.com)
  • Over-the-counter cimetidine is used to prevent and treat symptoms of heartburn associated with acid indigestion and sour stomach. (medlineplus.gov)
  • If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks, stop taking cimetidine and call your doctor. (medlineplus.gov)
  • A low initial starting dose is recommended to minimise the potential worsening of panic symptoms, which is generally recognised to occur early in the treatment of this disorder. (medicines.org.uk)
  • However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. (medlineplus.gov)
  • If a dose is missed and it is more than 8 hours of when it was due, the patient should only take the next dose at the usual time. (who.int)
  • If it is almost time for the next dose, do not take the missed dose. (cigna.com)
  • If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. (medbroadcast.com)
  • If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. (blueorangepharma.cc)
  • take the next dose at the usual dose and at the usual time. (theonlineclinic.co.uk)
  • If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. (somalinet.com)
  • If the migraine has not resolved by 2 hours after taking ZOMIG, or returns after a transient improvement, another dose may be administered at least 2 hours after the previous dose. (nih.gov)
  • Dosage adjustments should be made carefully on an individual patient basis, to maintain the patient at the lowest effective dose. (medicines.org.uk)
  • higher than usual doses may be required. (druglib.com)
  • Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. (antidepressantsfacts.com)
  • The dosing schedule described above is suitable for children and adolescents who weigh more than 25 kg. (who.int)
  • If you miss a dose, take it as soon as possible and continue with your regular schedule. (medbroadcast.com)
  • Venlafaxine and ODV exhibited linear kinetics over the dose range of 75 to 450 mg total dose per day (administered on a q8h schedule). (drugs.com)
  • If your physician has instructed or directed you to apply Pimecrolimus medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. (internationaldrugmart.com)
  • No set dosing schedule is available, but most studies advocate doses of 0.5-1 mg/kg/d until response, with rapid tapering to alternate day therapy. (medscape.com)
  • Uncommon: Pancreatitis (dose related, less common in children than adults), increased liver enzymes, and retinal depigmentation. (cdc.gov)
  • For participants in the dose-finding phase, a minimum washout period of at least 5 half-lives between the last dose of tyrosine kinase inhibitor (TKI) therapy and the first dose of study treatment is required. (dana-farber.org)
  • unless no other antiemetics are available, this antiemetic should not be used to treat vomiting associated with the use of atovaquone at treatment doses. (cdc.gov)
  • See main treatment section for doses. (antidepressantsfacts.com)