• It is a phthalate ester of containing benzyl alcohol, and n-butanol tail groups. (wikipedia.org)
  • Four compounds with varying physicochemical properties were studied under different conditions-benzyl alcohol (BA), diethyl-m-toluamide (DEET), tecnazene and malathion. (cdc.gov)
  • Vitamin E (as d-alpha-tocopherol, a natural source of vitamin E) 300 I.U. Compounded with 2% benzyl alcohol (preservative) in a water emulsifiable base. (vedco.com)
  • Each mL contains: 300 IU of vitamin E (as d-alpha-tocopherol, a natural source of vitamin E) compounded with 2% benzyl alcohol (preservative) in a water emulsifiable base. (premier1supplies.com)
  • Benzyl alcohol was not mutagenic in several Ames tests with Salmonella typhimurium TA92, TA94, TA98, TA100, TA1535, TA1537, and TA1538 with and without metabolic activation (e.g. (europa.eu)
  • Benzyl alcohol induced significant increase in chromosomal aberrations in CHO cells in the presence, but not in the absence of S9 (NTP TR343, 1989/Anderson et al. (europa.eu)
  • A Replicative DNA Synthesis assay using male Fischer 344 rats given a single dose of 0, 300 or 600 mg/kg bw benzyl alcohol by gavage was negative at all doses tested (Uno et al. (europa.eu)
  • 1994). A Replicative DNA Synthesis assay using male B6C3F1 male mice given a single dose of 0, 400 or 800 mg/kg bw benzyl alcohol by gavage was negative at all doses tested (Miyagawa et al. (europa.eu)
  • Active ingredient: Contains 200 mg phenylbutazone, 1.5% benzyl alcohol and purified water per ml. (powerhorsevet.com)
  • Benzyl Alcohol has a hydroxyl group (-OH), while the related compound, Benzoic Acid has a carboxyl group (-COOH). (cosmeticsinfo.org)
  • of Benzyl Alcohol and Benzoic Acid. (cosmeticsinfo.org)
  • Benzyl Alcohol is approved as an anesthetic ingredient in Over-the-Counter (OTC) anorectal, oral healthcare and topical analgesic drug products. (cosmeticsinfo.org)
  • The safety of Benzyl Alcohol and Benzyl Benzoate has been evaluated by the Research Institute for Fragrance Materials Expert Panel (REXPAN). (cosmeticsinfo.org)
  • The IFRA standards restrict the use of Benzyl Alcohol and Benzyl Benzoate in fragrances because of potential sensitization. (cosmeticsinfo.org)
  • The CIR Expert Panel reviewed data that indicated that inhalation exposure to Benzyl Alcohol and Benzoic Acid did not result in adverse effects. (cosmeticsinfo.org)
  • In one study, 5% Benzyl Alcohol elicited a reaction, and in another study, 2% Benzoic Acid did likewise. (cosmeticsinfo.org)
  • Additionally, Benzyl Alcohol was considered safe at up to 10% for use in hair dyes. (cosmeticsinfo.org)
  • Benzyl Alcohol and Benzyl Benzoate are also listed in in Annex III of the European Union Cosmetics Directive. (cosmeticsinfo.org)
  • also contains dextrose and benzyl alcohol (9 mg/mL). (medscape.com)
  • Also the other related benzyl derivatives (benzaldehyde, benzoic acid and the benzoate salts) were negative when tested in in vitro Ames tests with or without metabolic activation. (europa.eu)
  • 20% benzyl benzoate for low pip and 5 year. (24kkitchen.com)
  • and Benzyl Benzoate are also approved as a synthetic flavoring agents for direct addition to food. (cosmeticsinfo.org)
  • Benzyl butyl phthalate (BBP) is an organic compound historically used a plasticizer, but which has now been largely phased out due to health concerns. (wikipedia.org)
  • Those are mainly monobutyl and mono-benzyl phthalate (MBzP) plus small amounts of mono-n-butyl phthalate. (wikipedia.org)
  • While a major part of the BBP is excreted as a mono-benzyl phthalate metabolite, a minor fragment of the BBP is excreted in the form of mono-butyl phthalate. (wikipedia.org)
  • No repeated dose inhalation toxicity data are available on S278, but some insights can be gained from reliable studies on the structurally related compound, butyl benzyl phthalate (BBP). (europa.eu)
  • SCIENTIFIC OPINIONFlavouring Group Evaluation 54, Revision 1 (FGE.54Rev1) (2009):Consideration of benzyl derivatives evaluated by JECFA (57th meeting)structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoicacids and related esters evaluated by EFSA in FGE.20Rev1 (2009) 1Scientific Opinion of the Panel on Food Contact Materials, Enzymes,Flavourings and Processing Aids (CEF). (europa.eu)
  • Multi-Dose Vials: Each mL contains 100 mg trimethobenzamide hydrochloride compounded with 0.45% phenol as preservative, 0.5 mg sodium citrate and 0.2 mg citric acid as buffers and pH adjusted to approximately 5.0 with sodium hydroxide. (linkedlifedata.com)
  • Treatment-related toxicity is frequently a dose-limiting factor and represents a major challenge in clinical management of cancer. (aspetjournals.org)
  • One of the most frequently found compounds in the waters of the lagoon was benzyl salicylate - a chemical compound used in cosmetics as a fragrance additive or UV light absorbed and also known to cause dermal irritation. (siasat.com)
  • Papaya seeds contain benzyl isothiocyanate, a compound also found in many types of cruciferous vegetables ( 19 ). (healthline.com)
  • The compounds were 2-phenethyl isothiocyanate (PEITC), 3-phenylpropyl isothiocyanate (PPITC), N-acetyl-S-(N-benzyl-thiocarbamoyl)-L-cysteine (BITC-NAC), N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine (PEITC-NAC), and N-acetyl-S-(N-3-phenylpropylthiocarbamoyl)-L-cysteine (PPITC-NAC). (csbsju.edu)
  • The lowest lethal doses of diethyl phthalate in rabbits and guinea pigs administered the compound by gavage were determined to be 4,000 and 5,000 mg/kg, respectively (Smyth and Smyth 1931). (cdc.gov)
  • Depo-testosterone, en injection intramusculaire, fournit de la testostérone sous forme de cypionate et produit des taux de testostérone circulante qui. (jsantiagojr.com)
  • A single testosterone cypionate solution for injection (new formulation) 200 mg dose administered im deep in the gluteal muscle (test formulation). (jsantiagojr.com)
  • According to the latest science, volatile organic compounds (VOCs) coming from inside your home are worse for the environment than car fumes. (mamavation.com)
  • The volatile organic compounds (VOCs) emitting from common cleaning products in your home evaporate into the air. (mamavation.com)
  • Nevertheless, essential oils catch fire due to their high concentration of volatile organic compounds (VOCs), which are the main components in most essential oils. (fireinhibitor.com)
  • High Performance Liquid Chromatographic - Ultra Violet profiling and Liquid Chromatography - Mass Spectral analysis of crude Terminalia coriacea leaves methanolic extract were carried out as a part of chemical characterization to identify bioactive compounds. (afpm.org.my)
  • was cultured using One Strain Many Compounds (OSMAC) conditions as a model system to demonstrate how this strategy can help in understanding metabolic profiles and determining bioactive metabolites with the application of metabolomics and statistical analyses, as well as molecular networking. (bvsalud.org)
  • Though all the doses of TDFME exhibited gastroprotective function, higher doses were found to be more effective. (afpm.org.my)
  • RESULTS: All the test doses exhibited significant gastroprotective function, particularly the higher doses demonstrated improved action. (afpm.org.my)
  • Monobutyl phthalate is isolated and then added to a mixture of benzyl bromide in acetone in the presence of potassium carbonate (to keep the pH high to facilitate the substitution reaction required to form the second ester linkage), from which BBP can then be isolated. (wikipedia.org)
  • Essential oils are made from plants and often contain high concentrations of volatile compounds. (fireinhibitor.com)
  • These volatile compounds may be released as vapor or when the essential oil comes into contact with heat or flames. (fireinhibitor.com)
  • 1991. Recent methods for the determination of volatile and nonvolatile organic compounds in natural and purified drinking water. (cdc.gov)
  • Pharmacokinetic data collected at time intervals following a 60 mg/kg oral dose of acridine 1 and 2 showed both compounds penetrate the blood-brain barrier yielding peak concentrations of 0.25 μM and 0.6 μM, respectively. (umn.edu)
  • We used a tumor model in which A/J mice are treated with 8 weekly doses of benzo[a]pyrene (B[a]P) plus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and killed 19 weeks after the final treatment. (csbsju.edu)
  • No deaths were observed when diethyl phthalate was incorporated into the diet of mice for 2 weeks at doses of up to 6,500 mg/kg/day. (cdc.gov)
  • Compounded testosterone options include injectable testosterone in lower strengths (50mg/ml) for use in women who need replacement therapy. (jsantiagojr.com)
  • Papaya seeds are edible and contain fiber, healthy fatty acids, and other beneficial compounds, including polyphenols and flavonoids. (healthline.com)
  • What you have to remember here is that trenbolone is a VERY strong compound (5x as strong as testosterone), it is the strongest conventional anabolic steroid out there. (steroid.com)
  • Almost identical to the testosterone enanthate compound. (24kkitchen.com)
  • Administration of testosterone enanthate at doses of 300 mg im every 3. (24kkitchen.com)
  • Estimation of penetration rates of compounds through skin is an important for assessment of either the efficacy of a topical formulation, its irritation potential, or its potential systemic exposure. (cdc.gov)
  • But, we do not know the consequences of prolonged exposure to low doses of these substances," Vecchiato said. (siasat.com)
  • The points in the figure showing no-observed-adverse-effect levels (NOAELs) or lowest observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)
  • Comfrey tea contains the rodent carcinogen symphytine, and jasmine tea offers a hint of benzyl acetate. (acsh.org)
  • Conclusion: Taken overall, the results suggest compounds in this series may offer new strategies for the design of chemotherapeutics for treating brain cancers with high oral bioavailability and improved efficacy. (umn.edu)
  • total cell growth 20 %, lethal dose 5000 µg/mL). (europa.eu)
  • Single-Dose Vials: Each 2-mL single-dose vial contains 200 mg trimethobenzamide hydrochloride compounded with 1 mg sodium citrate and 0.4 mg citric acid as buffers and pH adjusted to approximately 5.0 with sodium hydroxide. (linkedlifedata.com)
  • N-Benzyl-N′N′-dimethyl-N-(2-pyridyl)ethylenediamine dihydrogen citrate is Tripelennamine Hydrochloride in Chemical name. (e-lactancia.org)
  • Organic solvents are a chemical class of compounds that are used routinely in commercial industries. (medscape.com)
  • Finally, it is concluded: "This evidence of safety is supported by the fact that the intake of benzyl derivatives as natural components of traditional foods is greater than their intake as intentionally added flavouring substances" (FEMA 2005). (europa.eu)
  • Conclusion on genotoxicity A total of 12 benzyl derivatives in the group have been tested for genotoxicity. (europa.eu)
  • In view of the mainly negative results in the assays in vitro and the uniformly negative results in well-recognised assays in vivo, the Committee concluded that the group of benzyl derivatives is not genotoxic in vivo. (europa.eu)
  • These new derivatives, along with previously synthesized 2-(p-substituted-benzyl)-5-substituted-benzoxazoles, were evaluated for their antibacterial and antifungal activities against standard strains and drugresistant isolates in comparison with ampicillin, gentamicin sulfate, ofloxacin, vancomycin, fluconazole, and amphotericin B trihydrate. (degruyter.com)
  • Absorption seems to be limited at high doses, meaning that small amounts are taken up more easily than great amounts. (wikipedia.org)
  • Absorption of 14C - BA, a perfume ingredient, was studied at different doses (0.9 µg/cm2 - 10.6 mg/cm2) through human cadaver skin and silicone membrane. (cdc.gov)
  • The small dose and poor plasma absorption of most topical dermatological preparations make it unlikely that a significant amount will pass into breast milk. (e-lactancia.org)
  • Research conducted on these species using modern analytical methods has led to advances in knowledge of the potential therapeutic use of compounds isolated not only from basidiocarps but also from biomass obtained by in vitro methods. (researchgate.net)
  • Antiallergic activity has been demonstrated by G. lucidum extracts, as well as some compounds isolated from this species, such as ganoderic acids, oleic acid, and cyclooctasulfur acid belonging to triterpenes [80]. (researchgate.net)
  • You can use a pill cutter to split the dose, or you can opt for smaller dosed tablets (5mg) when buying Methandrostenolone. (jsantiagojr.com)
  • 1977. Distribution of some organic compounds in the receiving waters of a kraft pulp and paper mill. (cdc.gov)
  • T. divaricata flower methanolic extract (TDFME) was screened for antiulcer activity versus aspirin and ethanol induced gastric ulcers at three doses--125, 250, and 500 mg/kg--orally using misoprostol as a standard. (afpm.org.my)
  • This is a multicenter, open-label, Phase 1/2a dose escalation and expansion study of orally administered emavusertib (CA-4948) monotherapy in adult patients with Acute Myelogenous Leukemia (AML) or high risk Myelodysplastic Syndrome (MDS). (rochester.edu)
  • We previously described the synthesis of 1-O-octadecyl-2-O-benzyl-glycero-3-phospho-RVn (V2043), an orally bioavailable lipid prodrug of remdesivir nucleoside (RVn, GS-441524) with broad spectrum antiviral activity against viruses with pandemic potential. (cdc.gov)
  • No other drugs or treatments are acceptable substitutes for prompt vitamin K dosing. (medscape.com)
  • Gibbons RJ, Engle LP. Vitamin K compounds in bacteria that are obligate anaerobes. (medscape.com)
  • For example, if you want to take a dose of 25mg per day and you only have 10mg pills, you could cut each pill in half (giving you 5mg), and take 5 doses throughout the day. (jsantiagojr.com)
  • Trenbolone is extremely versatile compound that can be used for both cutting AND bulking. (steroid.com)
  • So, with that being said, I think that there is no need to be running tren at very high doses (especially if it is your first time running trenbolone), and the reason why a lot of people say 'be careful, a lot of people can't take the sides' is because these people are running tren at unnecessarily high dosages. (steroid.com)
  • Capsules, 300 mg trimethobenzamide hydrochloride each, bottles of 100 NDC 61570-079-01 300 mg 100's Single-Dose Vials, 2 mL, trays of 25 NDC 61570-543-25 100 mg/mL in 2 mL Single-Dose Vials Multi-Dose Vials, 20 mL NDC 61570-541-20 100 mg/mL in 20 mL Multi-Dose Vials Prescribing Information as of November 2005. (linkedlifedata.com)
  • For example, one study found that administering large doses of papaya seed extract to monkeys caused a condition called azoospermia, which is characterized by a lack of sperm in the semen ( 17 ). (healthline.com)
  • An attempt was made to introduce a methyl group into 2-position of methyl 1-phenyl-5-oxo-3-pyrazolin-3-yl acetate (IVa) but it was found that a pyrazole-type compound (XI) was also produced besides the pyrazolone type (VIIIa) through this process. (go.jp)
  • Compound 35 was found to be promising, with an IC50 value of 2.8 μM. (atpasesignal.com)
  • At doses used in cosmetics and personal care products, the CIR Expert Panel was not concerned about potential reproductive and developmental effects. (cosmeticsinfo.org)
  • Molecular docking and molecular dy- namics (MD) simulation confirmed that compound 35 can bind tightly to NTCP. (atpasesignal.com)
  • It is recommended that one third of the daily dose be administered at 8 hour intervals. (powerhorsevet.com)
  • A silicone membrane study was performed with all three doses of 14C - malathion. (cdc.gov)
  • In this study, we discovered a novel NTCP inhibitor (compound 35) that inhibits the expression of NTCP. (atpasesignal.com)
  • Our study shows that compound 35, as an NTCP inhibitor, could be used as a candidate drug for future treatment of HCC. (atpasesignal.com)
  • As a proof-of-concept study, we used both minigenomes and recombinant viruses to test the inhibitory effects of previously reported antiviral compounds. (cdc.gov)
  • However, this study is limited in that only two to six animals were tested at each dose level and no control data were presented. (cdc.gov)
  • Future work entails conducting partitioning studies of lipophilic compounds to get better understanding of disposition of such compounds in the lower skin layers. (cdc.gov)
  • In test-tube studies, this compound has been associated with a number of health benefits, especially when it comes to cancer prevention ( 20 , 21 , 22 ). (healthline.com)
  • Previous studies by our laboratory have identified a series of 9-amino acridine compounds that block the catalytic cycle of topoisomerase II resulting in apoptosis and cell death in a variety of cancer cell lines. (umn.edu)
  • However, with an adeq battery of necf expsre blmarkers, prospective studies of en- vironmental effects on pregnancy outcomes might be possible. (cdc.gov)
  • Additional therapy if they are used in greater glasgow 1992/952078/89, doses of drugs repeatedly proven as significant determinants of whether desire is present. (themauimiracle.org)
  • Todays combination drugs mean lower doses of levodopa can be taken while still getting the same effect in the brain, which means fewer side effects and better symptom control. (parkinsonsdaily.com)
  • They should also help to determine whether or not the effects vary with dose and/or duration, and place into perspective the possible significance of these effects to human health. (cdc.gov)
  • METHODS: The test extract was screened for anti-ulcer activity by Aspirin induced ulcerogenesis in pyloric ligation and ethanol induced gastric ulcers at three doses - 125, 250, and 500 mg/kg, p.o. using Ranitidine 50 mg/kg and Misoprostol 100 μg/kg as standard drug in respective models. (afpm.org.my)
  • All other compounds aside from test (primo, anavar , deca , EQ, turinabol , and ESPECIALLY winny and pretty much every single other AAS out there) goes into the 'useless pile of shit bin' for me. (steroid.com)
  • They're treating it like test, or any other much weaker compound. (steroid.com)
  • A 'profile' is merely an article that provides the raw data and statistics on a compound as opposed to actual into on real world practicality. (steroid.com)
  • The results were further compared with data collected using a 15 mg/kg intravenous dose of 2 which yielded a peak concentration in the brain of 1.7 μM at 2.0 h relative to a 2.04 μM peak plasma concentration. (umn.edu)
  • Maintain lowest dose capable of producing desired clinical response. (powerhorsevet.com)
  • Altogether, these results indicate that compound 35 acts as a novel NTCP inhibitor to induce apoptosis in HepG2 cells. (atpasesignal.com)
  • If, hoping to avoid such compounds, you decide to skip the coffee and opt instead for a more "natural" herbal tea , think again. (acsh.org)
  • Coagulation factors should increase in 6-12 h after PO dosing and in 1-2 h after parenteral administration. (medscape.com)