• Dopachrome tautomerase, a human gene Pawelek JM (March 1991). (wikipedia.org)
  • Dopachrome tautomerase ( DCT ) was among the most overexpressed genes in RB in published studies. (molvis.org)
  • Data indicate that the caveolin-1 (CAV1) control on dopachrome tautomerase (DCT) gene expression, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent. (cusabio.com)
  • Report dopachrome tautomerase expression in mealanocytic tumors. (cusabio.com)
  • Data suggest that macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT) act cooperatively to inhibit steady-state phosphorylation and activation of AMPK in LKB1 wild type and LKB1 mutant non-small cell lung carcinomas cells. (cusabio.com)
  • The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury. (uni-koeln.de)
  • Researchers identified a cytokine, called macrophage migration inhibitory factor (MIF), along with its related protein, D-dopachrome tautomerase (D-DT), which are associated with progressive MS. These cytokines worsen the disease by increasing inflammation within the central nervous system. (neurosciencenews.com)
  • dopachrome tautomerase [Source:HGNC Sym. (gsea-msigdb.org)
  • Type VIII has been linked to a mutation in the dopachrome tautomerase (DCT) gene on chromosome 13q32, which encodes an enzyme that plays a role in modification of skin pigment color. (msdmanuals.com)
  • Tyrosinase (TYR) activity, expression of TYR, TYR-related protein 1 (TRP1) and TRP2 (dopachrome tautomerase, DCT), eumelanin synthesis, and the number of stage IV melanosomes markedly decreased in ru2 d /ru2 d melanocytes. (elsevierpure.com)
  • 2% Tyrosinase Control Complex - kojic acid, biotechnological plankton extract, tyrosinase control peptide alanine: stabilizing dopachrome. (crystalclearskin.co.za)
  • Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). (cusabio.com)
  • Dopachrome is a cyclization product of L-DOPA and is an intermediate in the biosynthesis of melanin. (wikipedia.org)
  • The initial oxidation product is dopachrome and this and related products form polymers which become attached to protein and distributed widely. (biomedres.us)
  • Dopachrome is a cyclization product of L-DOPA and is an intermediate in the biosynthesis of melanin. (wikipedia.org)
  • The reaction end product of TrT and AbT was studied via mass spectrometry and dopachrome was found to be the only reaction end product of L-DOPA oxidation catalysed by both tyrosinases. (aalto.fi)
  • Dopachrome produced by AbT-catalysed oxidation of L-DOPA was also shown to inhibit the TrT tyrosinase by an end product inhibition mechanism. (aalto.fi)