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  • lung transplant
  • That same evening, John was transported to UPMC Montefiore, where he had received his lung transplant years before. (upmc.com)
  • For months, 71-year-old Irma Myers-Santana and her younger sister, Anna Williamson, 69, had been debating who more urgently needed a lung transplant, each wanting the other to go first. (seacoastonline.com)
  • dialysis
  • A chain can start when an altruistic donor generously donates a kidney to a stranger on dialysis. (healthcanal.com)
  • The longer people are on dialysis before they have a transplant, the worse their survival,' he said. (scientificamerican.com)
  • But compared to $100,000 a year for dialysis,' he said, a transplant quickly becomes cost effective over time. (scientificamerican.com)
  • The authors show that patients who had preemptive transplants or less than 1 year of dialysis have better 5-year graft survival and more frequently return to full-time employment. (ovid.com)
  • The number of dialysis sessions through Day 30 for subjects who started dialysis beginning in the first 7 days post-transplant. (clinicaltrials.gov)
  • The proportion of subjects requiring dialysis for any reason in the first 7 days post-transplant. (clinicaltrials.gov)
  • It could slash the wait times for thousands of people and for some, like Clint Smith, a 56-year-old lawyer in New Orleans, mean the difference between receiving a transplant and spending the rest of their lives on dialysis . (nytimes.com)
  • Lancet
  • SAO PAULO) - In what could prove to be a major advancement for couples facing infertility, the first baby born from a deceased donor uterus transplant was successfully completed at the University Of Sao Paulo School of Medicine in Brazil, according to a report in the scientific journal Lancet . (kneb.com)
  • The case study - published in The Lancet - in Brazil demonstrates that uterus donations from deceased donors are a potential avenue of treatment for women with uterine infertility. (sky.com)
  • Uterine
  • The use of deceased donors could greatly broaden access to this treatment, and our results provide proof-of-concept for a new option for women with uterine infertility," Ejzenberg said in a journal news release. (healthday.com)
  • Uterine transplants from living donors have occurred before. (sky.com)
  • researchers
  • The Brazilian researchers are planning two more uterus transplants as part of the study. (thenorthwestern.com)
  • Researchers estimate about half of the 100,000 people in the United States on waiting lists for a kidney transplant have antibodies that will attack a transplanted organ, and about 20 percent are so sensitive that finding a compatible organ is all but impossible. (nytimes.com)
  • KYOTO, Japan, April 18-Researchers have successfully reversed a patient's diabetes by transplanting insulin-producing islet cells from the pancreas of a living donor. (medpagetoday.com)
  • In an editorial accompanying the report, British physicians commended the researchers on their achievement but noted that the donor in this case had undergone "a significant operation and exposed herself to increased risk of diabetes as a result of the loss of part of her own pancreas. (medpagetoday.com)
  • The Kyoto researchers, they said, are in a position to "ethically explore whether such donors can safely provide more robust successes, and the diabetes world should watch their progress with great interest. (medpagetoday.com)
  • Some researchers are experimenting in animals with living-donor transplants of pieces of lungs and small bowels. (nytimes.com)
  • rejection
  • So if you have a living donor, instead of waiting five years for a compatible donor, if you can get a transplant from an incompatible donor in a couple of months, this paper suggests that that is beneficial, despite the fact that they have a higher rate of rejection,' he told Reuters Health. (scientificamerican.com)
  • For living donor transplants, rejection and graft survival rates are related to donor source. (ovid.com)
  • The major risks associated with this process are organ rejection through blood type mismatch, inadequate immune system suppression or severe infection of the transplanted organ. (kneb.com)
  • MDR-103 is intended to induce mixed lymphohematopoietic chimerism and donor specific immune tolerance in order to preserve transplant kidney function, avert transplant kidney rejection, and eliminate the cumulative and serious side effects associated with immunosuppressive drugs. (clinicaltrials.gov)
  • Hospital
  • She said she wanted to be my donor that first night in the hospital while I was waiting to come to Pittsburgh," says John. (upmc.com)
  • While babies born from live donor uterus transplants have been done nearly a dozen times before, including once in 2017 at Baylor Scott & White Hospital in Dallas, this birth marks the first time doctors have been able to remove the uterus from a recently deceased donor and have it result in a live birth. (kneb.com)
  • Medical team hold the first baby born via uterus transplant from a deceased donor at the hospital in Sao Paulo, Brazil December 15, 2017 in this picture handout obtained on December 4, 2018. (reuters.com)
  • This Dec. 15, 2017 photo provided by transplant surgeon Dr. Wellington Andraus shows the baby girl born to a woman with a uterus transplanted from a deceased donor at the Hospital das Clinicas of the University of Sao Paulo School of Medicine, Sao Paulo, Brazil, on the day of her birth. (thenorthwestern.com)
  • To minimize the risk of impaired glucose tolerance in the donor, doctors at Kyoto University Hospital made sure that she was not obese, that she had a healthy glucose pattern and insulinogenic index during an oral glucose tolerance test, and that antibody concentrations of glutamic acid decarboxylase and insulin were normal. (medpagetoday.com)
  • Earlier this month, though, the sisters ended up in the same operating room, each getting one lung from the same donor in what doctors at Houston Methodist Hospital say is a first for their facility. (seacoastonline.com)
  • They live in California, but Houston Memorial is the only hospital in the country that does such transplants. (seacoastonline.com)
  • If we hadn't had the transplant when we did, she would be dead right now, dead," Williamson said adamantly, her sister sitting beside her in the hospital room. (seacoastonline.com)
  • womb
  • LONDON, Dec 4 (Reuters) - A woman in Brazil who received a womb transplanted from a deceased donor has given birth to a baby girl in the first successful case of its kind, doctors reported. (reuters.com)
  • She added, however, that the outcomes and effects of womb donations from live and deceased donors have yet to be compared, and said the technique could still be refined and optimized. (reuters.com)
  • The first baby born after a live donor womb transplant was in Sweden in 2013. (reuters.com)
  • Eleven previous births have used a transplanted womb but from a living donor, usually a relative or friend. (koreaherald.com)
  • A mother has given birth to a healthy baby girl after surgeons implanted a womb in her body from a deceased donor. (sky.com)
  • immune
  • The company plans to launch additional Phase 2 studies to evaluate the potential of FCR001 to treat certain severe auto-immune or immune-mediated disorders, as well as to induce durable immune tolerance in other organ transplant settings. (businesswire.com)
  • The purpose of the current Phase 2 study is to demonstrate the efficacy and safety of MDR-103 for the induction of transplant immune tolerance in a prospective, multicenter clinical trial. (clinicaltrials.gov)
  • The trial of nivolumab - which blocks a protein called PD-1 that can blunt the immune system's attack on cancer - was spurred by retrospective studies that showed that the drug could be effective but often produced harsh side effects, including graft-versus-host disease, a disorder in which immune system cells in transplanted tissue attack a patient's healthy cells. (eurekalert.org)