Donor somatic cell cloned mammal clone cells. Medical search. Frequent questions

The resulting cells would be genetically identical to the somatic cell donor, thus avoiding any complications from immune system rejection. (wikipedia.org)
Snuppy is genetically identical to the donor Afghan hound. (nature.com)
We tested whether the cloned dogs were genetically identical by microsatellite analysis of genomic DNA from the donor Afghan, the cloned dogs and the surrogates (see supplementary information ). (nature.com)
Analysis of eight canine-specific microsatellite loci confirmed that the cloned dogs were genetically identical to their donor dog. (nature.com)
Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)
In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
The word "cloning" refers to a variety of procedures that may be used to create biological copies that are genetically identical to the original. (geminigenetics.com)
Asexual reproduction is a natural method used by certain plants, bacteria, and single-celled creatures to create genetically identical offspring, i.e. clones. (geminigenetics.com)
This is the most known form of cloning and involves creating a genetically identical replica of a whole organism. (geminigenetics.com)
The resulting embryo is then implanted into a surrogate mother, resulting in the birth of an animal genetically identical to the body cell donor. (geminigenetics.com)
Pet cloning is the process where a genetically identical twin is created of your original animal companion. (geminigenetics.com)
As the fertilized egg divides from one cell into two, physicians can separate these two cells and implant each one of them into a woman's uterus to generate two genetically identical children. (jcpa.org)
Any offspring of that cell will be genetically identical to the parent cell. (scienews.com)

The technique consists of taking an denucleated oocyte (egg cell) and implanting a donor nucleus from a somatic (body) cell. (wikipedia.org)
Somatic cell nuclear transfer is a technique for cloning in which the nucleus of a somatic cell is transferred to the cytoplasm of an enucleated egg. (wikipedia.org)
After the somatic cell transfers, the cytoplasmic factors affect the nucleus to become a zygote. (wikipedia.org)
After being inserted into the egg, the somatic cell nucleus is reprogrammed by its host egg cell. (wikipedia.org)
The ovum, now containing the somatic cell's nucleus, is stimulated with a shock and will begin to divide. (wikipedia.org)
Typically, a detergent is used to break down the cell membranes and release the DNA from the nucleus of the cell. (scinotions.com)
Dolly was created by removing the nucleus of an egg cell and replacing it with the nucleus from a somatic cell of a donor sheep. (scinotions.com)
The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
The process of reproductive cloning involves the nucleus of a somatic (body) cell from a donor organism to be cloned being transferred into an egg cell whose nucleus (genetic material) has been removed. (geminigenetics.com)
The DNA within the skin sample is cultured and inserted into a donor egg cell whose nucleus (genetic material) has been removed. (geminigenetics.com)
The surrogate mum carries the cloned pet for the gestation period and once ready, gives birth to the clone who will be an identical genetic twin to the original pet whose skin sample was used to make the nucleus of the donor egg cell. (geminigenetics.com)
It was clear that a definitive experiment required the replacement of a zygote nucleus by a somatic cell nucleus, asking whether the somatic nucleus could functionally replace the zygote nucleus by eliciting normal development of the enucleated recipient egg ( Fig. 1 )? (biologists.com)
Briggs and King ( Briggs and King, 1952 ) had already succeeded in transplanting a blastula cell nucleus into an enucleated egg and obtaining normal tadpoles in the frog Rana pipiens . (biologists.com)
However, Briggs and King ( Briggs and King, 1957 ) had also found that the nucleus of an endoderm cell from a neurula embryo could no longer support normal development ( Fig. 2 ). (biologists.com)
They pioneered a new technique of starving embryo cells before transferring their nucleus to fertilized egg cells. (shawprize.org)
One of the live-born lambs, Dolly, was derived from the transplantation of the nucleus of an adult mammary cell. (shawprize.org)

The blastocyst stage is developed by the egg to help create embryonic stem cells from the inner cell mass of the blastocyst. (wikipedia.org)
Development will ensue normally and after many mitotic divisions, the single cell forms a blastocyst (an early stage embryo with about 100 cells) with an identical genome to the original organism (i.e. a clone). (wikipedia.org)
A blastocyst (cloned or not), because it lacks any trace of a nervous system, has no capacity for suffering or conscious experience in any form - the special properties that, in our view, spell the difference between biological tissue and a human life worthy of respect and rights. (wikiquote.org)
In SCNT they take the nucleolus out of an egg cell, replace it with the nucleolus of a somatic cell (body cell with two complete sets of chromosomes), and make the egg cell divide into a blastocyst ("What Is Cloning? (bartleby.com)
Therapeutic cloning involves the creation of an early-stage embryo (blastocyst) and the removal of stem cells from the developing embryo. (geminigenetics.com)
Most researchers obtain embryonic stem cells from the inner mass of a blastocyst, an embryonic stage when a fertilized egg has divided into 128 cells. (jcpa.org)
The stem cells derived from the inner mass of a blastocyst lack the ability to form a fetus when implanted into a woman, but are self-renewing and can be maintained for long periods of time in the laboratory as undifferentiated stem cells. (jcpa.org)

In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. (wikipedia.org)
In human SCNT experiments, these eggs are obtained through consenting donors, utilizing ovarian stimulation. (wikipedia.org)
Controversy surrounds human ESC work due to the destruction of viable human embryos, leading scientists to seek alternative methods of obtaining pluripotent stem cells, SCNT is one such method. (wikipedia.org)
For example, if a person with Parkinson's disease donated their somatic cells, the stem cells resulting from SCNT would have genes that contribute to Parkinson's disease. (wikipedia.org)
Another application of SCNT stem cell research is using the patient specific stem cell lines to generate tissues or even organs for transplant into the specific patient. (wikipedia.org)
Only a handful of the labs in the world are currently using SCNT techniques in human stem cell research. (wikipedia.org)
Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)
For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)
Dolly was the first mammal to be cloned from an adult somatic cell using the technique called somatic cell nuclear transfer (SCNT). (scinotions.com)
Indeed, if passed, Hatch/Feinstein/Kerry would explicitly legalize doing in humans the very cloning procedure -- somatic cell nuclear transfer (SCNT) -- that was used to make Dolly the sheep . (lifeissues.net)
Comment: Indeed, if passed, "total cloning bans" H.R. 534, H.R. 234, H.R. 916, and S. 245 would not ban anything either - not even the SCNT cloning technique that was used to make Dolly the sheep. (lifeissues.net)
Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
Somatic cell nuclear transfer (SCNT) is a type of cloning that has to be done in a lab. (bartleby.com)

In 1996, Dolly the sheep became famous for being the first successful case of the reproductive cloning of a mammal. (wikipedia.org)
One of the most famous cloning experiments was the cloning of Dolly the sheep in 1996. (scinotions.com)
Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
The cloning of 'Dolly The Sheep' in 1996 by the Rosalind Institute in Scotland, UK, is the most recognised example of reproductive cloning. (geminigenetics.com)
Although Dolly the sheep is the most famous animal ever cloned with the help of science, it is obviously not the only one in its kind: scientists have cloned mice, cats and several types of livestock in addition to sheep. (scienews.com)
In 2014, scientists created human stem cells by the same technique of cloning, which created Dolly the sheep. (scienews.com)
Thus, Dolly was the first example of the reprogramming of the adult cell back to totipotency in a mammal. (shawprize.org)
is a British developmental biologist who was the first to use nuclear transfer of differentiated adult cells to generate a mammalian clone, a Finn Dorset sheep named Dolly, born in 1996. (mathisfunforum.com)

It is used in both therapeutic and reproductive cloning. (wikipedia.org)
Stem cells can then be obtained by the destruction of this clone embryo for use in therapeutic cloning or in the case of reproductive cloning the clone embryo is implanted into a host mother for further development and brought to term. (wikipedia.org)
Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
Therapeutic cloning refers to the production of embryonic stem cells for medicinal reasons, for example regenerative medicine and tissue replacement. (geminigenetics.com)
Scientists call this process "therapeutic" cloning, that is cloning for medical and therapeutic purposes, and distinguish it from traditional cloning, which has reproductive implications. (scienews.com)
Since then, the work of Wilmut and Campbell has been duplicated in many other animal species and has provided approaches to produce useful therapeutic products with cloned animals and to improve agricultural practices. (shawprize.org)

These cells genetically matched the donor organism from which they came. (wikipedia.org)
These cells are deemed to have a pluripotent potential because they have the ability to give rise to all of the tissues found in an adult organism. (wikipedia.org)
On the other hand, a chimera is defined as an organism in which cells from two or more different organisms have contributed. (frontiersin.org)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
A new organism is created by asexual reproduction using a duplicate of a single cell from the parent organism. (geminigenetics.com)
Stem cell research is, in part, a quest to understand cellular differentiation, the process by which a human being develops from one fertilized cell into a multicellular organism composed of over 200 different cell types - for example muscle, nerve, blood cell, or kidney. (jcpa.org)
The fertilized egg is considered totipotent, as it can develop into a whole organism, while the cells in the embryo are pluripotent because they are capable of differentiating into somatic cells that make up all the organs. (shawprize.org)

Somatic cell nuclear transplantation has become a focus of study in stem cell research. (wikipedia.org)
As a brand new graduate student starting in October 1956, my supervisor Michail Fischberg, a lecturer in the department of Zoology at Oxford, suggested that I should try to make somatic cell nuclear transplantation work in the South African frog Xenopus laevis . (biologists.com)

Numerous biological components, including genes, cells, tissues, and even complete creatures like sheep, have been cloned by researchers, and now cat, dog and equine cloning is widely and reliably available via international companies such as our partner, ViaGen Pets & Equine. (geminigenetics.com)
They performed nuclear transfer experiments in which nuclei from embryonic, foetal and adult cells of the sheep were transplanted into fertilized eggs derived from ewes. (shawprize.org)
They further created a sheep called Polly in which they showed that it was possible to incorporate a human gene into the donor's DNA before cloning, thus indicating that it may be possible to use animals to produce human proteins for the benefit of mankind. (shawprize.org)

To take human organ generation via BC and transplantation to the next step, we reviewed current emerging organ generation technologies and the associated efficiency of chimera formation in human cells from the standpoint of developmental biology. (frontiersin.org)

Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
Contrary to popular belief, stem cells are present in the human body throughout life and are found in many adult organs. (jcpa.org)
The scientists honoured by the 2008 Shaw Prize in Life Science and Medicine used different approaches to reprogramme an adult cell into the totipotent or pluripotent state, and in doing so made important contributions to potential new approaches to improve agriculture practices and to treat human diseases. (shawprize.org)

this approach has been championed as an answer to the many issues concerning embryonic stem cells (ESCs) and the destruction of viable embryos for medical use, though questions remain on how homologous the two cell types truly are. (wikipedia.org)
Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)

Elaboration of an international convention against reproductive cloning of human beings has been under consideration in the United Nations since December 2001 when the subject was included in the agenda of the fifty- sixth session as a supplementary agenda item at the request of France and Germany. (who.int)
Since the term "born" has been used as an essential part of the definition of " reproductive cloning " used by Weissman, the National Academy of Sciences, etc., then it is critical to use the accurate term with the proper meaning. (lifeissues.net)
Reproductive cloning is expensive and highly inefficient. (wikiquote.org)

Embryonic stem cells are undifferentiated cells of an embryo. (wikipedia.org)
In the United States, scientists at the Harvard Stem Cell Institute, the University of California San Francisco, the Oregon Health & Science University, Stemagen (La Jolla, CA) and possibly Advanced Cell Technology are currently researching a technique to use somatic cell nuclear transfer to produce embryonic stem cells. (wikipedia.org)
Cellular differentiation begins with the fertilized egg which serves as the identifying characteristic of an embryonic stem cell. (jcpa.org)
The predominant bioethical concern arising from this technology is that the blastocyt-stage embryo must be destroyed in the process of isolating and separating the embryonic stem cells from the inner mass region of the pre-embryo. (jcpa.org)
The destruction of the pre-embryo has been the critical issue in the U.S. behind imposing limits on federal government-sponsored research in embryonic stem cells. (jcpa.org)
In 2009, in a major reversal of U.S. policy, President Obama signed an executive order pledging to "vigorously support" embryonic stem cell research. (jcpa.org)
This policy is similar to that of other countries, including Israel, where scientists are funded by Government to study embryonic stem cells despite the aforementioned bioethical issue. (jcpa.org)
In 1995, they produced a pair of lambs called Megan and Morag from embryonic cells. (shawprize.org)

The Ethical Debate Concerning Cloning In the year that has elapsed since the announcement of Dolly's birth, there has been much discussion of the ethical implications of cloning humans. (bartleby.com)
However, the idea of cloning humans is a highly charged topic. (bartleby.com)
Humans and other mammals may produce natural clones, commonly referred to as identical twins. (geminigenetics.com)
Although science has come a long way in this direction in the last century, when it came to cloning, zoo animals, humans and primates, there was always an insuperable obstacle. (scienews.com)
While in humans reproduction is the result of combining two cells (one from each parent, each with its own DNA), the method of cellular photocopies really takes place in nature. (scienews.com)
During the development of vertebrates, including humans, the fertilized egg develops into the embryo, and the cells in the embryo then proceed to differentiate to form somatic cells of different tissues and organs. (shawprize.org)

In January 2018, a team of scientists in Shanghai announced the successful cloning of two female crab-eating macaques (named Zhong Zhong and Hua Hua) from foetal nuclei. (wikipedia.org)
This question had been asked by embryologists since 1886 ( Rauber, 1886 ), and Spemann ( Spemann, 1938 ) had demonstrated by an egg ligation experiment that the nuclei of an eight-cell frog embryo are developmentally totipotent. (biologists.com)
Even advanced donor cells from the endoderm of Xenopus tadpoles have nuclei that can sometimes yield normal individuals after nuclear transfer [data taken from Briggs and King ( Briggs and King, 1957 ) for Rana and from Gurdon ( Gurdon, 1962 ) for Xenopus ]. (biologists.com)

Although the simple use of the word 'clone' may have negative connotations, many people have resigned themselves to the idea of cloning cows that produce more milk or using a cloned mouse for use in controlled experimentation. (bartleby.com)
Cloning cows in recent years has provided scientists with an understanding of why they did not get everything: starting with problems during implantation and ending with the aforementioned mutations, which lead to the death of offspring. (scienews.com)

The genetic material of the donor egg cell is removed and discarded, leaving it 'deprogrammed. (wikipedia.org)
Hair is an exceptional source of DNA since it holds nucleated cells that contain genetic material. (scinotions.com)
It is not feasible to clone a human using only hair as the source of DNA since hair cells do not contain the complete set of genetic material necessary for human cloning. (scinotions.com)
Although hair contains nucleated cells with genetic material, the DNA within them is often degraded and insufficient for cloning. (scinotions.com)
Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)

The present report gives an overview of the terms and methods used in cloning and summarizes the debates in the General Assembly. (who.int)
Über uns as of the MCS buy how to get people to do things has a important IgG risk magnitude cell( SP, recombinant) for the histidine of different methods. (kaminbau-altmann.de)

Instead, it may depend on the host and donor molecular similarities or distinctions critical for the organogenesis program. (frontiersin.org)
Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
Molecular cloning refers to the production of multiple copies of a DNA fragment or gene. (geminigenetics.com)

The aim of carrying out this procedure is to obtain pluripotent cells from a cloned embryo. (wikipedia.org)

Half a century ago, it was found by John Gurdon that this developmental clock can be reversed, and that differentiated somatic cells in a frog model could regain their pluripotency or totipotency. (shawprize.org)
Attempts were then made to show that mammalian cells - and human cells in particular - could also be reprogrammed back to a pluripotent state, because it is believed that such knowledge may advance our understanding of developmental mechanisms, and yield new approaches for disease treatment. (shawprize.org)

A type of cloning that occurs naturally is when identical twins are born ("What Is Cloning? (bartleby.com)
There are also naturally occurring clones among animal populations. (geminigenetics.com)
As well as their distinctive white markings and long curved horns, these cattle are special because they are now considered a herd of naturally occurring clones. (geminigenetics.com)

Click on any transcript to open the specific mRNA page, to see the exact cDNA clone support and eventual SNPs and to get details on tissues, sequences, mRNA and protein annotations. (nih.gov)

Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
Imagine a world in which human beings can be replicated using cloning. (visit-now.net)

However, donor organs are in absolute shortage, and sadly, most patients die while waiting for a donor organ. (frontiersin.org)
Presently, in the United States, another person is added to an organ transplant list every 10 min, 17 people die each day while waiting for donor organs, and approximately 105,800 patients are waitlisted for an organ transplant according to the health resources and services administration (HRSA). (frontiersin.org)

In sexual reproduction, clones are created when a fertilized egg splits to produce identical (monozygous) twins with identical genomes. (who.int)
Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)

a , Snuppy, the first cloned dog, at 67 days after birth (right), with the three-year-old male Afghan hound (left) whose somatic skin cells were used to clone him. (nature.com)
Other notable cloning experiments include the cloning of a cat named CC (Carbon Copy) in 2001, the cloning of a mule named Idaho Gem in 2003, and the cloning of a dog named Snuppy in 2005. (scinotions.com)

The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)

Gene cloning refers to the identification and duplication of a single gene or a DNA segment, for the intention of investigating its function or creating a particular protein. (geminigenetics.com)

Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)

This ability allows stem cells to create any cell type, which could then be transplanted to replace damaged or destroyed cells. (wikipedia.org)
A potential use of stem cells genetically matched to a patient would be to create cell lines that have genes linked to a patient's particular disease. (wikipedia.org)
The disease specific stem cell lines could then be studied in order to better understand the condition. (wikipedia.org)
It's given name is the "Human Cloning Ban and Stem Cell Research Protection Act of 2003," the stated purpose of which, supposedly, is to "prohibit human cloning and to protect important areas of medical research, including stem cell research. (lifeissues.net)
The recovered stem cells can then be used in the treatment of diseases and to aid the recovery of injuries. (geminigenetics.com)
In order to better appreciate the role of stem cell research in reproductive medicine, there is a need to understand the critical biological principles of stem cell research and its potential applications to medicine. (jcpa.org)
While there is a great deal published on the potential medical applications of stem cell research to treat or cure diseases such as diabetes, Alzheimer's disease, Parkinson's disease, cancer, and heart disease, much less has been published on the future impact of stem cell research in reproductive medicine. (jcpa.org)
In addition, specific proteins or biological substances can be added to these stem cell cultures to transform them in the laboratory into a large variety of specialized cell types, such as nerve, liver, muscle, bone, and blood cells. (jcpa.org)
As the stem cells can be made to be any cells of the body, in the treatment of diseases they will be most helpful - especially genetic diseases or when the patient requires a transplant of another organ donor which is often unavailable. (scienews.com)

However, it's important to note that cloning is still a relatively new technology and has many limitations and ethical concerns that need to be addressed before it can be used widely. (scinotions.com)
Though pet cloning may be considered a relatively new technology, the process of cloning as defined above is first documented in 1885, where Hans Adolf Eduard Driesch demonstrated artificial embryo twinning on a sea-urchin. (geminigenetics.com)

If there are intact cells in this tissue they have been 'stored' frozen. (wikiquote.org)
It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)

And while it may seem that the choice inherent to cloning can circumvent these potential genetic disadvantages, scientists have found that it is not necessary. (scienews.com)
Harris Lewin, Professor, Department of evolution and ecology, University of California at Davis, and its scientists published work on the implications of cloning for gene expression in the journal proceedings of the National Academy of Sciences in 2016. (scienews.com)

We have developed a powerful pipeline to systematically discover drug resistance in mammalian cells in vitro . (biomedcentral.com)

I think no one understood how difficult it would be to clone some species and easy - to others. (scienews.com)

The process of somatic cell nuclear transfer involves two different cells. (wikipedia.org)

Are there any successful experiments in cloning so far? (scinotions.com)
There have been no successful human cloning experiments, and human cloning is currently illegal in most countries. (scinotions.com)
In his experiments, Bridges studied Drosophila, the common fruit fly, and by doing so showed that a process called nondisjunction caused chromosomes, under some circumstances, to fail to separate when forming sperm and egg cells. (asu.edu)

The first obstacle to cloning your dog is that $100,000 cost. (wikiquote.org)

Nondisjunction, as described by Bridges, caused sperm or egg cells to contain abnormal amounts of chromosomes. (asu.edu)

The technique synchronized the cell cycles of both cells and the results led Wilmut and Campbell to believe that any type of cell could be used to produce a clone. (shawprize.org)

The second being a somatic cell, referring to the cells of the human body. (wikipedia.org)
However, if we think back to what actually happened to the animal - it died, even if from the cold, the cells in the body would have taken some time to freeze. (wikiquote.org)
You can clone a dog that has been dead for fewer than five days, too, as long as you wrap its body in wet towels and place it in a refrigerator, which keeps it from drying out before getting to the vet. (wikiquote.org)
The very important question to be addressed at that time was whether all cell types in the body have the same set of genes. (biologists.com)

This process allows people to clone living things of any sort. (bartleby.com)

This approach uses a modified piggyBac transposon to generate libraries of mutagenized cells, each containing transposon insertions that randomly activate nearby gene expression. (biomedcentral.com)

Unlike other mammals, dogs ovulate at first meiotic prophase, and their oocytes mature for 2 to 3 days in the oviduct's distal regions. (nature.com)
Unlike some movies, cloning in real life doesn't produce a full grown exact replica of someone. (bartleby.com)

However, since clones are the exact replicas of someone already alive, their genetic dispositions will have already surfaced. (bartleby.com)

More than 90% of cloning attempts fail to produce viable offspring. (wikiquote.org)
More than 100 nuclear transfer procedures could be required to produce one viable clone. (wikiquote.org)
Analysis of co-occurring transposons integration sites in single cell clone allows for the identification of genes that might act cooperatively to produce drug resistance a level of information not accessible using RNAi or ORF expression screening approaches. (biomedcentral.com)

However, though BC is emerging as a potential organ transplant option, challenges regarding organ size scalability, immune system incompatibilities, long-term maintenance, potential evolutionary distance, or unveiled mechanisms between donor and host cells remain. (frontiersin.org)
The term "clone", from the Greek word for twig, denotes a group of identical entities. (who.int)
a) It would seem that Saunders uses the "potential" argument here quite appropriately, but it is critical that the term be understood properly in order to deflect any misunderstandings or misinterpretations - especially if the term were to be used in any U. N. treaty on human cloning. (lifeissues.net)
If the term "potential" were to be incorporated into a U. N. treaty on human cloning, it would be necessary to clarify its use as referring to an already existing human being/person. (lifeissues.net)

But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)

A clone is a copy of a substance that shares the same genetic make-up as the original. (geminigenetics.com)

Anatomy2

Organisms1

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes3

Information Science3

Named Groups3

Genetically identical14

Nucleus18

Blastocyst7

SCNT13

Dolly9

Therapeutic6

Organism7

Nuclear transplantation2

Sheep3

Transplantation1

Adult5

Embryos2

Reproductive Cloning3

Embryonic8

Humans6

Nuclei3

Cows2

Genetic material5

Methods2

Molecular3

Procedure1

Developmental2

Naturally3

Tissues1

Human beings2

Organs2

Genomes2

Snuppy2

Organisms1

Refers1

Livestock1

Stem9

Relatively new technology2

Tissue2

Scientists2

Mammalian cells1

Species1

Involves1

Experiments3

Obstacle1

Chromosomes1

Technique1

Body4

Process1

Gene expression1

Unlike2

Replicas1

Produce3

Term4

Frog1

Make1