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  • transplant
  • In corneal transplant, also known as keratoplasty, a patient's damaged cornea is replaced by the cornea from the eye of a human cadaver. (encyclopedia.com)
  • Corneal transplant is used when vision is lost because the cornea has been damaged by disease or traumatic injury, and there are no other viable options. (encyclopedia.com)
  • Other conditions that might make a corneal transplant necessary are tissue growth on the cornea (pterygium) and Stevens-Johnson syndrome, a skin disorder that can affect the eyes. (encyclopedia.com)
  • The herpes virus produces one of the more common infections leading to corneal transplant. (encyclopedia.com)
  • Occasionally, corneal transplant is combined with other eye surgery such as cataract surgery to solve multiple eye problems with one procedure. (encyclopedia.com)
  • The Eye Bank Association of America reported that corneal transplant recipients range in age from nine days to 103 years. (encyclopedia.com)
  • In a corneal transplant, a disc of tissue is removed from the center of the eye and replaced by a corresponding disc from a donor eye. (encyclopedia.com)
  • No special preparation for corneal transplant is needed. (encyclopedia.com)
  • Corneal transplant is often performed on an outpatient basis, although some patients need brief hospitalization after surgery. (encyclopedia.com)
  • precut
  • The rapid success and utilization of this procedure can be attributed to availability of eye-bank prepared precut tissue. (jove.com)
  • collagen
  • Retention of corneal architecture, collagen and glycosaminoglycans was assessed via histological, immunofluorescence and quantitative analysis. (lboro.ac.uk)
  • A bi-functional epoxy-based cross-linker, 1,4-Butanediol diglycidyl ether (BDDGE), was investigated in the fabrication of collagen based corneal substitutes. (mdpi.com)
  • infection
  • Characteristics of Pseudomonas corneal infection related to orthokeratology. (medscape.com)
  • These findings enhance our understanding of the pathophysiology of corneal inflammation during infection. (jove.com)
  • Characteristics
  • Thus, the sequential dynamic culture process that was designed according to corneal physiological characteristics could successfully reconstruct an auto-lamellar cornea with favorable morphological characteristics and satisfactory physiological function. (jove.com)
  • To assess characteristics of donor corneal tissues with positive scleral rim cultures and postkeratoplasty infections. (arvojournals.org)
  • Data collected included: donor cornea characteristics from the eye-bank database, surgery performed, microbiology laboratory reports, and post-operative course. (arvojournals.org)
  • There were no statistically significant differences in donor characteristics of the tissues with positive scleral rim cultures or postkeratoplasty infections, including age, sex, race, death to procurement time, or death to surgery time. (arvojournals.org)
  • peripheral
  • Compared with the peripheral corneal limbus, the human central cornea lacks blood vessels, which is responsible for its immunologically privileged status and high transparency. (jove.com)
  • shortage
  • Reprocessing the tissue has the potential to have a considerable impact on addressing the problems associated with cadaveric donor shortage. (lboro.ac.uk)
  • synthetic
  • Decellularized tissues are advantageous compared to synthetic or semi-synthetic engineered tissues in that the native matrix ultrastructure and intrinsic biological cues including growth factors, cytokines and glycosaminoglycans may be retained. (lboro.ac.uk)
  • years
  • A long-term study of 33 families over a period of 18 years reveals that most morbidity derives from progressive corneal clouding, leading to glare and decreased vision in daylight. (medscape.com)
  • vision
  • Nevertheless, while scotopic vision remained relatively good, increasing corneal opacification with age resulted in decreased scotopic vision. (medscape.com)