Dolichol monophosphate mannose is a chemical compound involved in glycosylation. (wikipedia.org)
Product1
Glucose transfer from doliochol monophosphate glucose: the product formed with endogenous microsomal acceptor. (neglectedscience.com)
Mannosyltransferase2
We have studied the effectiveness of polyprenyl-P-mannose and polyprenol-P-glucose as donor substrates for the dolichyl-P-mannose:Man5(GlcNAc)2-PP-dolichol mannosyltransferase and the dolichyl-P-glucose:Man9(GlcNAc)2-PP-dolichol glucosyltransferase, respectively. (nih.gov)
Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. (nih.gov)
Synthase1
catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex. (nih.gov)
Phosphate2
The mutant cell line was partially defective in MPDU1, which encodes a protein required for the utilization of dolichol-phosphate mannose. (nih.gov)
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). (nih.gov)
Biosynthesis1
A lipophilic glycosyl carrier of the monosaccharide mannose in the biosynthesis of oligosaccharide phospholipids and glycoproteins. (nih.gov)
Glycosyl1
Mammalian glycosyltransferases prefer glycosyl phosphoryl dolichols rather than glycosyl phosphoryl polyprenols as substrates for oligosaccharyl synthesis. (nih.gov)
Terms1
These findings are significant in terms of understanding the glycosylation phenotypes of Chinese hamster ovary cell mutants of the Lec9 complementation group, which lack the ability to convert polyprenol into dolichol. (nih.gov)