Dna lesions response to dna damage. Medical search. Frequent questions

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Anatomy18

Cell Line Cell Line, Tumor HeLa Cells Fibroblasts Cells, Cultured Chromatin Cell Nucleus Lymphocytes Skin Tumor Cells, Cultured Telomere Brain Liver Micronuclei, Chromosome-Defective HCT116 Cells Chromosomes, Fungal Mitochondria HEK293 Cells

Organisms8

Saccharomyces cerevisiae Escherichia coli Mice, Knockout Mice, Inbred C57BL Cricetinae Schizosaccharomyces Cricetulus Rats, Sprague-Dawley

Diseases14

Genomic Instability Xeroderma Pigmentosum DNA Repair-Deficiency Disorders Cockayne Syndrome Ataxia Telangiectasia Disease Models, Animal Neoplasms Chromosome Aberrations Precancerous Conditions Brain Damage, Chronic Skin Neoplasms Micronuclei, Chromosome-Defective Fanconi Anemia Cell Transformation, Neoplastic

Chemicals and Drugs125

Deoxyguanosine Ataxia Telangiectasia Mutated Proteins DNA DNA Adducts Cell Cycle Proteins DNA-Binding Proteins Pyrimidine Dimers Guanine Methyl Methanesulfonate Checkpoint Kinase 2 DNA Glycosylases DNA Repair Enzymes Tumor Suppressor Protein p53 Mutagens Protein-Serine-Threonine Kinases DNA-Directed DNA Polymerase DNA-Formamidopyrimidine Glycosylase Tumor Suppressor Proteins Histones Nuclear Proteins Alkylating Agents Xeroderma Pigmentosum Group A Protein Saccharomyces cerevisiae Proteins Poly(ADP-ribose) Polymerases Hydrogen Peroxide Proliferating Cell Nuclear Antigen DNA Polymerase beta Rad51 Recombinase Reactive Oxygen Species DNA Helicases DNA-(Apurinic or Apyrimidinic Site) Lyase Endodeoxyribonucleases N-Glycosyl Hydrolases DNA, Fungal Replication Protein A Apurinic Acid Chromatin Protein Kinases Endonucleases Deoxyadenosines Deoxyribodipyrimidine Photo-Lyase Carcinogens DNA, Single-Stranded Guanosine BRCA1 Protein Mitomycin Poly Adenosine Diphosphate Ribose Hydroxyurea Methylnitronitrosoguanidine Exodeoxyribonucleases Escherichia coli Proteins Thymine Intracellular Signaling Peptides and Proteins DNA-Activated Protein Kinase Acetoxyacetylaminofluorene Deoxyribonuclease (Pyrimidine Dimer)4-Nitroquinoline-1-oxide Antioxidants 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Chromates Nucleic Acid Synthesis Inhibitors Antigens, Nuclear RNA, Small Interfering Cisplatin Antineoplastic Agents Oligonucleotides 2-Acetylaminofluorene Rad52 DNA Repair and Recombination Protein Zinostatin Oxidants Rec A Recombinases Ubiquitin-Protein Ligases Ubiquitin-Conjugating Enzymes Cross-Linking Reagents Fanconi Anemia Complementation Group D2 Protein Schizosaccharomyces pombe Proteins Ubiquitin Deoxycytosine Nucleotides RecQ Helicases Adenosine Triphosphatases Transcription Factors Nucleotidyltransferases DNA, Neoplasm Benzo(a)pyrene DNA Topoisomerases, Type I Deoxyribonuclease IV (Phage T4-Induced)Chromosomal Proteins, Non-Histone Cell Extracts Carcinogens, Environmental MutS DNA Mismatch-Binding Protein DNA Ligases DNA Primers Proto-Oncogene Proteins c-mdm2 Free Radicals Fungal Proteins O(6)-Methylguanine-DNA Methyltransferase RNA, Messenger Cyclin-Dependent Kinase Inhibitor p21 Deoxyribonucleosides Topoisomerase I Inhibitors Chromium Cytosine Nucleotides Camptothecin cdc25 Phosphatases Acrolein Bleomycin DNA Topoisomerases, Type II Doxorubicin Enzyme Inhibitors Bacterial Proteins Exonucleases Aldehydes DNA, Bacterial RNA Polymerase II Hydroxyl Radical Hydantoins Topoisomerase II Inhibitors DNA, Mitochondrial DNA Polymerase III Aphidicolin Uracil-DNA Glycosidase Carbon-Oxygen Lyases Etoposide Xeroderma Pigmentosum Group D Protein

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Comet Assay Dose-Response Relationship, Radiation Mutagenicity Tests Models, Biological Micronucleus Tests Blotting, Western Disease Models, Animal Immunohistochemistry Magnetic Resonance Imaging Flow Cytometry Microscopy, Fluorescence Transfection Models, Genetic Immunoblotting Models, Molecular Gene Knockdown Techniques Reverse Transcriptase Polymerase Chain Reaction In Situ Nick-End Labeling Polymerase Chain Reaction Chromatography, High Pressure Liquid

Phenomena and Processes78

DNA Damage DNA Repair Ultraviolet Rays DNA Adducts DNA Breaks, Double-Stranded DNA Replication Oxidative Stress DNA Breaks, Single-Stranded Mutation Cell Cycle Gamma Rays Genomic Instability Apoptosis DNA Breaks Dose-Response Relationship, Radiation SOS Response (Genetics)Cell Survival Mutagenesis G2 Phase Phosphorylation Time Factors Radiation Tolerance S Phase Base Sequence Recombination, Genetic Signal Transduction Chromatin Cell Cycle Checkpoints Oxidation-Reduction Genes, cdc Linear Energy Transfer Protein Binding X-Rays DNA, Single-Stranded Homologous Recombination Base Pair Mismatch Mitosis Ubiquitination Cell Aging Transcription, Genetic Dose-Response Relationship, Drug Sister Chromatid Exchange Cell Death Alkylation Kinetics Radiation, Ionizing Protein Structure, Tertiary RNA Interference Amino Acid Sequence G2 Phase Cell Cycle Checkpoints Gene Deletion Telomere Base Pairing Chromosome Aberrations Recombinational DNA Repair Plasmids Cell Proliferation Genes, p53 Lipid Peroxidation Chromatin Assembly and Disassembly Gene Expression Regulation DNA Fragmentation Cell Division Micronuclei, Chromosome-Defective DNA Mismatch Repair Nucleic Acid Conformation Phenotype DNA End-Joining Repair Transfection Substrate Specificity Sumoylation G1 Phase Enzyme Activation Binding Sites Chromosomes, Fungal Aging Epistasis, Genetic Gene Expression

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care2

Ultraviolet Rays Dose-Response Relationship, Radiation

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

DNA Damage DNA Repair Comet Assay Ultraviolet Rays Deoxyguanosine Ataxia Telangiectasia Mutated Proteins DNA DNA Adducts Cell Cycle Proteins DNA Breaks, Double-Stranded DNA-Binding Proteins Pyrimidine Dimers Guanine DNA Replication Methyl Methanesulfonate Checkpoint Kinase 2 DNA Glycosylases Oxidative Stress DNA Repair Enzymes Tumor Suppressor Protein p53 Mutagens DNA Breaks, Single-Stranded Protein-Serine-Threonine Kinases DNA-Directed DNA Polymerase Mutation Cell Cycle Gamma Rays DNA-Formamidopyrimidine Glycosylase Tumor Suppressor Proteins Histones Genomic Instability Nuclear Proteins Apoptosis DNA Breaks Alkylating Agents Dose-Response Relationship, Radiation Xeroderma Pigmentosum Group A Protein SOS Response (Genetics)Saccharomyces cerevisiae Proteins Cell Line Cell Survival Saccharomyces cerevisiae Mutagenesis G2 Phase Poly(ADP-ribose) Polymerases Hydrogen Peroxide Proliferating Cell Nuclear Antigen Cell Line, Tumor Xeroderma Pigmentosum DNA Polymerase beta Rad51 Recombinase Phosphorylation Reactive Oxygen Species HeLa Cells DNA Helicases DNA-(Apurinic or Apyrimidinic Site) Lyase Endodeoxyribonucleases Time Factors N-Glycosyl Hydrolases Radiation Tolerance S Phase Molecular Sequence Data Base Sequence Fibroblasts DNA, Fungal Cells, Cultured Replication Protein A Recombination, Genetic Signal Transduction Apurinic Acid Chromatin Cell Cycle Checkpoints Oxidation-Reduction Genes, cdc Cell Nucleus Protein Kinases Endonucleases Mutagenicity Tests Linear Energy Transfer Protein Binding Deoxyadenosines Deoxyribodipyrimidine Photo-Lyase Carcinogens X-Rays DNA, Single-Stranded Guanosine Models, Biological BRCA1 Protein Mitomycin Homologous Recombination Base Pair Mismatch Poly Adenosine Diphosphate Ribose Hydroxyurea Methylnitronitrosoguanidine Exodeoxyribonucleases Escherichia coli Proteins Mitosis Ubiquitination Thymine Cell Aging

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