• The core RNA polymerase complex forms a "crab claw"-like structure with an internal channel running along the full length [ PMID: 10499798 ]. (ebi.ac.uk)
  • Consistent with RdDM at the GFP locus in GxA plants, GFP DNA methylation is lost in flowers of rdr6 and sgs3 mutants along with GFP siRNAs ( 1 ) ( Fig. 1C ). (sciencemag.org)
  • In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. (uniprot.org)
  • Viruses may initially have adopted DNA as a way to resist RNA-degrading enzymes in the host cells. (wikipedia.org)
  • In archaebacteria, there is generally a single form of RNA polymerase which also consists of an oligomeric assemblage of 10 to 13 polypeptides. (ebi.ac.uk)
  • The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity). (nih.gov)
  • The existence of this distinct silencing polymerase may explain the paradoxical involvement of an RNA silencing pathway in maintenance of transcriptional silencing. (sciencemag.org)
  • We previously identified an Arabidopsis sde4 mutant that exhibited partial loss of a transgene-silencing pathway that is otherwise dependent on RNA-dependent RNA polymerase 6 (RDR6) ( 1 ). (sciencemag.org)
  • The sde4 mutant plants were also defective for small interfering RNA (siRNA) production and methylation of the SINE retroelement AtSN1 ( 2 ) in a pathway that was subsequently associated with RDR2, Dicer-like 3 (DCL3), and other endogenous siRNAs ( 3 ). (sciencemag.org)
  • It is likely that this silencing pathway is related to the RNA interference (RNAi)-mediated heterochromatinization in Schizosaccharomyces pombe that is also dependent on siRNA, Dicer, and an RDR ( 4 ). (sciencemag.org)
  • Binds RNA. (uniprot.org)
  • An area with three bases on a tRNA molecule which binds to the corresponding three bases on the messenger RNA attached to a ribosome. (abpischools.org.uk)
  • A DNA-based virus may have provided storage for an ancient host that had previously used RNA to store its genetic information (such host is called ribocell or ribocyte). (wikipedia.org)
  • In 2006, researchers suggested that the transition from RNA to DNA genomes first occurred in the viral world. (wikipedia.org)
  • A short piece of DNA which is responsible for the inheritance of a particular characteristic. (abpischools.org.uk)
  • p>Used to indicate a direct assay for the function, process or component indicated by the GO term. (uniprot.org)
  • Over 150 unique RNA modifications are now known including several nonstandard nucleotides present in the body of messenger RNAs. (usda.gov)