Dna damage signaling pathways. Medical search. Frequent questions

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Anatomy17

Cell Line, Tumor Cell Line HeLa Cells Cells, Cultured Fibroblasts Cell Nucleus Chromatin HCT116 Cells Micronuclei, Chromosome-Defective Telomere Lymphocytes Tumor Cells, Cultured Spermatozoa Mitochondria HEK293 Cells Liver Skin

Organisms7

Saccharomyces cerevisiae Mice, Knockout Schizosaccharomyces Mice, Inbred C57BL Rats, Sprague-Dawley Cricetinae Escherichia coli

Diseases12

Genomic Instability Micronuclei, Chromosome-Defective Ataxia Telangiectasia Brain Damage, Chronic Xeroderma Pigmentosum Chromosome Aberrations Disease Models, Animal Neoplasms Chromosomal Instability Aging, Premature Fanconi Anemia Cell Transformation, Neoplastic

Chemicals and Drugs104

Ataxia Telangiectasia Mutated Proteins Cell Cycle Proteins Deoxyguanosine Checkpoint Kinase 2 Tumor Suppressor Protein p53 DNA-Binding Proteins Protein-Serine-Threonine Kinases Tumor Suppressor Proteins DNA Methyl Methanesulfonate Histones Mutagens Nuclear Proteins DNA Repair Enzymes DNA Adducts Reactive Oxygen Species Hydrogen Peroxide Protein Kinases Poly(ADP-ribose) Polymerases Rad51 Recombinase DNA Glycosylases Saccharomyces cerevisiae Proteins BRCA1 Protein Hydroxyurea Antioxidants DNA-Activated Protein Kinase Intracellular Signaling Peptides and Proteins Chromatin Alkylating Agents Replication Protein A DNA Helicases Poly Adenosine Diphosphate Ribose RNA, Small Interfering Proto-Oncogene Proteins c-mdm2 Pyrimidine Dimers DNA-Formamidopyrimidine Glycosylase Mitomycin Cyclin-Dependent Kinase Inhibitor p21 Nucleic Acid Synthesis Inhibitors Guanine Xeroderma Pigmentosum Group A Protein DNA, Fungal Oxidants Endodeoxyribonucleases cdc25 Phosphatases Proliferating Cell Nuclear Antigen Antigens, Nuclear Endonucleases Carcinogens Schizosaccharomyces pombe Proteins Antineoplastic Agents 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Etoposide Exodeoxyribonucleases Ubiquitin Ubiquitin-Protein Ligases Chromosomal Proteins, Non-Histone 4-Nitroquinoline-1-oxide Zinostatin DNA, Single-Stranded Transcription Factors RecQ Helicases N-Glycosyl Hydrolases Telomeric Repeat Binding Protein 2 DNA, Neoplasm DNA-(Apurinic or Apyrimidinic Site) Lyase Antimutagenic Agents Cisplatin Free Radicals Superoxide Dismutase DNA-Directed DNA Polymerase Doxorubicin Camptothecin Free Radical Scavengers Antibiotics, Antineoplastic Radiation-Protective Agents Glutathione Fanconi Anemia Complementation Group D2 Protein Catalase Enzyme Inhibitors Topoisomerase I Inhibitors DNA, Mitochondrial CDC2 Protein Kinase RNA, Messenger Methylnitronitrosoguanidine DNA Topoisomerases, Type I Fungal Proteins Serine Rad52 DNA Repair and Recombination Protein Carrier Proteins Topoisomerase Inhibitors Radiation-Sensitizing Agents Biological Markers Rec A Recombinases E2F1 Transcription Factor Multiprotein Complexes Ubiquitin-Conjugating Enzymes Caspase 3 Malondialdehyde Benzo(a)pyrene Ascorbic Acid Proto-Oncogene Proteins Escherichia coli Proteins DNA Primers

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Comet Assay Dose-Response Relationship, Radiation Micronucleus Tests Models, Biological Blotting, Western Mutagenicity Tests Flow Cytometry In Situ Nick-End Labeling Microscopy, Fluorescence Disease Models, Animal Transfection Gene Knockdown Techniques Immunoblotting Immunohistochemistry Reverse Transcriptase Polymerase Chain Reaction Immunoprecipitation

Phenomena and Processes77

DNA Damage DNA Repair Ultraviolet Rays DNA Breaks, Double-Stranded Oxidative Stress Cell Cycle Gamma Rays Apoptosis Genomic Instability G2 Phase DNA Replication Mutation Phosphorylation Dose-Response Relationship, Radiation DNA Adducts Cell Survival DNA Breaks Radiation Tolerance Genes, cdc Cell Cycle Checkpoints DNA Breaks, Single-Stranded Signal Transduction S Phase Mitosis Cell Aging G2 Phase Cell Cycle Checkpoints Chromatin X-Rays Time Factors Recombinational DNA Repair Protein Binding Oxidation-Reduction Cell Death SOS Response (Genetics)Recombination, Genetic Micronuclei, Chromosome-Defective Ubiquitination Telomere DNA End-Joining Repair Dose-Response Relationship, Drug RNA Interference Homologous Recombination Genes, p53 DNA Fragmentation Lipid Peroxidation Base Sequence Cell Proliferation Transcription, Genetic Gene Expression Regulation Linear Energy Transfer Sister Chromatid Exchange Gene Deletion DNA, Single-Stranded Amino Acid Sequence Mutagenesis Protein Structure, Tertiary Chromatin Assembly and Disassembly S Phase Cell Cycle Checkpoints G1 Phase Chromosome Aberrations Enzyme Activation Transfection Cell Division Chromosomal Instability Acetylation Down-Regulation Protein Processing, Post-Translational Plasmids Aging Alkylation Phenotype Stress, Physiological Up-Regulation Infrared Rays Gene Expression Regulation, Fungal Gene Expression Regulation, Neoplastic Kinetics

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care3

Ultraviolet Rays Dose-Response Relationship, Radiation Infrared Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

DNA Damage DNA Repair Comet Assay Ataxia Telangiectasia Mutated Proteins Cell Cycle Proteins Ultraviolet Rays Deoxyguanosine Checkpoint Kinase 2 Tumor Suppressor Protein p53 DNA-Binding Proteins DNA Breaks, Double-Stranded Protein-Serine-Threonine Kinases Oxidative Stress Cell Cycle Tumor Suppressor Proteins Gamma Rays Apoptosis DNA Methyl Methanesulfonate Histones Mutagens Nuclear Proteins Genomic Instability G2 Phase DNA Replication Mutation Phosphorylation Cell Line, Tumor DNA Repair Enzymes Dose-Response Relationship, Radiation DNA Adducts Reactive Oxygen Species Cell Survival Cell Line Hydrogen Peroxide DNA Breaks Radiation Tolerance Protein Kinases Poly(ADP-ribose) Polymerases Genes, cdc Cell Cycle Checkpoints DNA Breaks, Single-Stranded Signal Transduction Rad51 Recombinase DNA Glycosylases HeLa Cells S Phase Saccharomyces cerevisiae Proteins BRCA1 Protein Cells, Cultured Fibroblasts Mitosis Cell Aging Micronucleus Tests Saccharomyces cerevisiae Cell Nucleus Hydroxyurea Antioxidants DNA-Activated Protein Kinase G2 Phase Cell Cycle Checkpoints Intracellular Signaling Peptides and Proteins Chromatin Alkylating Agents X-Rays Time Factors Replication Protein A Recombinational DNA Repair Models, Biological Protein Binding DNA Helicases Oxidation-Reduction Poly Adenosine Diphosphate Ribose Cell Death RNA, Small Interfering Molecular Sequence Data SOS Response (Genetics)Proto-Oncogene Proteins c-mdm2 Recombination, Genetic Pyrimidine Dimers DNA-Formamidopyrimidine Glycosylase Mitomycin HCT116 Cells Micronuclei, Chromosome-Defective Ubiquitination Cyclin-Dependent Kinase Inhibitor p21 Telomere Nucleic Acid Synthesis Inhibitors DNA End-Joining Repair Blotting, Western Mutagenicity Tests Guanine Dose-Response Relationship, Drug Xeroderma Pigmentosum Group A Protein Lymphocytes DNA, Fungal Ataxia Telangiectasia Oxidants Endodeoxyribonucleases cdc25 Phosphatases Proliferating Cell Nuclear Antigen

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