Dna damage repair mechanisms response to dna damage. Medical search. Frequent questions

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Anatomy19

Cell Line, Tumor Cell Line HeLa Cells Fibroblasts Chromatin Cells, Cultured Cell Nucleus Telomere HEK293 Cells HCT116 Cells Lymphocytes Tumor Cells, Cultured Micronuclei, Chromosome-Defective Mitochondria Stem Cells Spermatozoa Brain Neurons Skin

Organisms7

Saccharomyces cerevisiae Mice, Knockout Schizosaccharomyces Escherichia coli Mice, Inbred C57BL Cricetinae Rats, Sprague-Dawley

Diseases15

Genomic Instability Aging, Premature Neoplasms Xeroderma Pigmentosum Chromosome Breakage Breast Neoplasms Disease Models, Animal Chromosome Aberrations Micronuclei, Chromosome-Defective Ataxia Telangiectasia Brain Damage, Chronic Aortic Aneurysm, Abdominal Fanconi Anemia Chromosomal Instability DNA Repair-Deficiency Disorders

Chemicals and Drugs113

Ataxia Telangiectasia Mutated Proteins DNA-Binding Proteins DNA Repair Enzymes Cell Cycle Proteins Lead Radioisotopes Rad51 Recombinase DNA Glycosylases Nuclear Proteins BRCA1 Protein Checkpoint Kinase 2 Protein-Serine-Threonine Kinases DNA Histones Tumor Suppressor Protein p53 Tumor Suppressor Proteins DNA-Activated Protein Kinase Poly(ADP-ribose) Polymerases DNA Helicases Saccharomyces cerevisiae Proteins Deoxyguanosine Mutagens Antigens, Nuclear Chromatin Pyrimidine Dimers Methyl Methanesulfonate Proliferating Cell Nuclear Antigen BRCA2 Protein Fanconi Anemia Complementation Group A Protein DNA Adducts Radiation-Sensitizing Agents Endodeoxyribonucleases Deoxyribodipyrimidine Photo-Lyase Mitomycin Hydrogen Peroxide RNA, Small Interfering Protein Kinases Fanconi Anemia Complementation Group D2 Protein Alkylating Agents Exodeoxyribonucleases Intracellular Signaling Peptides and Proteins Antineoplastic Agents Chromosomal Proteins, Non-Histone Endonucleases Guanine DNA-(Apurinic or Apyrimidinic Site) Lyase Schizosaccharomyces pombe Proteins N-Glycosyl Hydrolases Rad52 DNA Repair and Recombination Protein DNA-Formamidopyrimidine Glycosylase DNA Ligases Ubiquitin Reactive Oxygen Species Multiprotein Complexes DNA, Fungal Apurinic Acid RNA, Messenger Ubiquitin-Protein Ligases Transcription Factors DNA-Directed DNA Polymerase DNA, Neoplasm Thymine Carcinogens Replication Protein A Xeroderma Pigmentosum Group A Protein Hydroxyurea RecQ Helicases Carbon-Oxygen Lyases Carrier Proteins Lysine Antioxidants DNA, Mitochondrial Escherichia coli Proteins Poly Adenosine Diphosphate Ribose Cisplatin Deoxyribonuclease (Pyrimidine Dimer)DNA Primers Cross-Linking Reagents Proto-Oncogene Proteins c-mdm2 Cyclin-Dependent Kinase Inhibitor p21 Nucleic Acid Synthesis Inhibitors DNA, Single-Stranded Oxidants 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Oligonucleotides DNA, Bacterial cdc25 Phosphatases 4-Nitroquinoline-1-oxide Bacterial Proteins Histone Acetyltransferases Etoposide Methylnitronitrosoguanidine Uracil Zinostatin DNA Polymerase beta Fungal Proteins Telomeric Repeat Binding Protein 2 Repressor Proteins Antimutagenic Agents Adenosine Triphosphatases Neoplasm Proteins Rec A Recombinases Camptothecin Enzyme Inhibitors Free Radicals Superoxide Dismutase Antibiotics, Antineoplastic Topoisomerase I Inhibitors Doxorubicin Radiation-Protective Agents Glutathione DNA Topoisomerases, Type I Free Radical Scavengers Catalase

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Comet Assay Dose-Response Relationship, Radiation Models, Biological Blotting, Western Gene Expression Profiling Gene Knockdown Techniques Reverse Transcriptase Polymerase Chain Reaction Micronucleus Tests Immunohistochemistry Models, Genetic Disease Models, Animal Oligonucleotide Array Sequence Analysis Flow Cytometry Mutagenicity Tests Xenograft Model Antitumor Assays In Situ Nick-End Labeling Transfection Microscopy, Fluorescence Chromatin Immunoprecipitation Polymerase Chain Reaction

Phenomena and Processes89

DNA Damage DNA Repair Ultraviolet Rays DNA Breaks, Double-Stranded Radiation Tolerance DNA End-Joining Repair Genomic Instability Gamma Rays Cell Cycle Mutation Oxidative Stress Dose-Response Relationship, Radiation Apoptosis Recombinational DNA Repair DNA Replication Recombination, Genetic Radiation, Ionizing Cell Survival Linear Energy Transfer G2 Phase Homologous Recombination Signal Transduction Phosphorylation X-Rays Chromatin Base Sequence Protein Binding DNA Adducts S Phase Cell Proliferation Mitosis Ubiquitination Time Factors Chromatin Assembly and Disassembly Cell Cycle Checkpoints RNA Interference Transcription, Genetic Amino Acid Sequence Acetylation Telomere DNA Breaks, Single-Stranded DNA Breaks Gene Expression Regulation Oxidation-Reduction Wound Healing Cell Aging Protein Structure, Tertiary Gene Expression Regulation, Neoplastic Sister Chromatid Exchange Genes, cdc DNA Mismatch Repair Base Pair Mismatch Mutagenesis Protein Processing, Post-Translational Genes, BRCA1 Drug Resistance, Neoplasm Down-Regulation Chromosome Breakage Radiation Effects G2 Phase Cell Cycle Checkpoints Regeneration Dose-Response Relationship, Drug SOS Response (Genetics)Plasmids Cell Death Chromosome Aberrations Kinetics Aging Micronuclei, Chromosome-Defective Cell Division DNA, Single-Stranded Genes, p53 Phenotype Gene Deletion DNA Fragmentation Lipid Peroxidation Up-Regulation Protein Transport Gene Silencing Genotype Sequence Homology, Amino Acid Gene Expression Transfection G1 Phase Alkylation S Phase Cell Cycle Checkpoints Chromosomal Instability Enzyme Activation Promoter Regions, Genetic

Disciplines and Occupations2

Radiation Genetics Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care4

Ultraviolet Rays Dose-Response Relationship, Radiation Radiation Genetics Radiation Effects

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

DNA Damage DNA Repair Ultraviolet Rays DNA Breaks, Double-Stranded Comet Assay Ataxia Telangiectasia Mutated Proteins DNA-Binding Proteins DNA Repair Enzymes Cell Cycle Proteins Radiation Tolerance Lead Radioisotopes Rad51 Recombinase DNA End-Joining Repair Genomic Instability Gamma Rays Cell Cycle DNA Glycosylases Nuclear Proteins BRCA1 Protein Checkpoint Kinase 2 Protein-Serine-Threonine Kinases DNA Histones Tumor Suppressor Protein p53 Mutation Oxidative Stress Dose-Response Relationship, Radiation Tumor Suppressor Proteins Apoptosis Recombinational DNA Repair Cell Line, Tumor DNA-Activated Protein Kinase DNA Replication Recombination, Genetic Radiation, Ionizing Cell Survival Poly(ADP-ribose) Polymerases Linear Energy Transfer DNA Helicases G2 Phase Saccharomyces cerevisiae Proteins Cell Line Deoxyguanosine Mutagens HeLa Cells Saccharomyces cerevisiae Aging, Premature Antigens, Nuclear Homologous Recombination Signal Transduction Phosphorylation X-Rays Molecular Sequence Data Fibroblasts Models, Biological Chromatin Cells, Cultured Pyrimidine Dimers Methyl Methanesulfonate Base Sequence Proliferating Cell Nuclear Antigen Protein Binding BRCA2 Protein Fanconi Anemia Complementation Group A Protein DNA Adducts Radiation-Sensitizing Agents Neoplasms Endodeoxyribonucleases Deoxyribodipyrimidine Photo-Lyase Mitomycin Cell Nucleus Hydrogen Peroxide S Phase Cell Proliferation RNA, Small Interfering Mitosis Protein Kinases Ubiquitination Time Factors Fanconi Anemia Complementation Group D2 Protein Alkylating Agents Exodeoxyribonucleases Blotting, Western Chromatin Assembly and Disassembly Intracellular Signaling Peptides and Proteins Antineoplastic Agents Cell Cycle Checkpoints RNA Interference Chromosomal Proteins, Non-Histone Endonucleases Mice, Knockout Guanine DNA-(Apurinic or Apyrimidinic Site) Lyase Schizosaccharomyces pombe Proteins Transcription, Genetic Amino Acid Sequence N-Glycosyl Hydrolases Rad52 DNA Repair and Recombination Protein Schizosaccharomyces DNA-Formamidopyrimidine Glycosylase

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