DNA DamageDNA Breaks, Single-StrandedComet AssayDNA, Single-StrandedDNA Repairtert-ButylhydroperoxideDeoxycytosine NucleotidesDNAUltraviolet RaysPoly(ADP-ribose) PolymerasesDeoxyguanosineMutagensCell SurvivalCell Cycle ProteinsGamma RaysDNA ReplicationCell CycleDNA-Binding ProteinsAtaxia Telangiectasia Mutated ProteinsApoptosisMutationBase SequenceCheckpoint Kinase 2Tumor Suppressor Protein p53DNA Breaks, Double-StrandedProtein-Serine-Threonine KinasesEscherichia coliOxidative StressTumor Suppressor ProteinsMethyl MethanesulfonateHistonesNuclear ProteinsGenomic InstabilityG2 PhasePhosphorylationCell Line, TumorDNA Repair EnzymesDose-Response Relationship, RadiationDNA AdductsReactive Oxygen SpeciesCell LineHydrogen PeroxideDNA BreaksRadiation ToleranceProtein KinasesGenes, cdcCell Cycle CheckpointsSignal TransductionRad51 RecombinaseDNA GlycosylasesHeLa CellsS PhaseSaccharomyces cerevisiae ProteinsBRCA1 ProteinCells, CulturedFibroblastsMitosisCell AgingMicronucleus TestsSaccharomyces cerevisiaeCell NucleusHydroxyureaAntioxidantsDNA-Activated Protein KinaseG2 Phase Cell Cycle CheckpointsIntracellular Signaling Peptides and ProteinsChromatinAlkylating AgentsX-RaysTime FactorsReplication Protein ARecombinational DNA RepairModels, BiologicalProtein BindingDNA HelicasesOxidation-ReductionPoly Adenosine Diphosphate RiboseCell DeathRNA, Small InterferingMolecular Sequence DataSOS Response (Genetics)Proto-Oncogene Proteins c-mdm2Recombination, GeneticPyrimidine DimersDNA-Formamidopyrimidine GlycosylaseMitomycinHCT116 CellsMicronuclei, Chromosome-DefectiveUbiquitinationCyclin-Dependent Kinase Inhibitor p21TelomereNucleic Acid Synthesis InhibitorsDNA End-Joining RepairBlotting, WesternMutagenicity TestsGuanineDose-Response Relationship, DrugXeroderma Pigmentosum Group A ProteinLymphocytesDNA, Fungal