DNA DamageCheckpoint Kinase 2Cell Cycle ProteinsGenes, cdcG2 PhaseDNA RepairAtaxia Telangiectasia Mutated ProteinsProtein-Serine-Threonine KinasesCell CycleProtein KinasesMitosisMethyl MethanesulfonateS PhaseSaccharomyces cerevisiae ProteinsDNA ReplicationCell Cycle CheckpointsUltraviolet RaysDNA-Binding ProteinsDNA Breaks, Double-StrandedNuclear ProteinsSchizosaccharomycesSaccharomyces cerevisiaeSchizosaccharomyces pombe ProteinsHydroxyureaPhosphorylationTumor Suppressor ProteinsComet AssayGenomic InstabilityMutationGamma RaysTumor Suppressor Protein p53Intracellular Signaling Peptides and Proteinscdc25 PhosphatasesG2 Phase Cell Cycle CheckpointsDNA, FungalM Phase Cell Cycle CheckpointsHistonesMutagensCDC2 Protein KinaseS Phase Cell Cycle CheckpointsSignal TransductionRadiation, IonizingRecombinational DNA RepairFungal ProteinsReplication Protein CExodeoxyribonucleasesDNACyclin BDose-Response Relationship, RadiationReplication Protein AHeLa CellsG1 PhaseSpindle ApparatusApoptosisDNA Repair EnzymesNocodazoleCell Line, TumorRad51 RecombinaseRecombination, GeneticModels, BiologicalTelomereNucleic Acid Synthesis InhibitorsBRCA1 ProteinGene Expression Regulation, FungalChromatinEndodeoxyribonucleasesSecurinras-GRF1Chromosomal Proteins, Non-HistoneCell LineCell NucleusRNA, Small InterferingRadiation ToleranceDNA HelicasesDeoxyguanosineChromosomes, FungalProtein BindingAnaphaseCell SurvivalMolecular Sequence DataCyclin-Dependent Kinase Inhibitor p21Genes, FungalHomologous RecombinationChromosome SegregationRad52 DNA Repair and Recombination ProteinOxidative StressExonucleasesEndonucleasesMeiosisSaccharomycetalesTelomere-Binding ProteinsChromosomal InstabilityKinetochoresFibroblastsX-RaysHCT116 CellsAmino Acid SequenceCaffeineGene DeletionEpistasis, Genetic