• This is attained by spinally administering the overall transcription inhibitor actinomycin D and the overall translation inhibitor anisomycin spinally, to formalin shot in to the hind paw prior. (researchensemble.com)
  • 22Rv1 cells were pre-treated with the pan-caspase inhibitor z-VAD(OMe)-fmk or vehicle (DMSO) for 1 h prior to treatment with the investigated drugs ( C , D ). PC-3, LNCaP, and MRC-9 cells were treated with the investigated drugs without pre-treatment with z-VAD(OMe)-fmk ( E ). Cells that appeared in the lower right and upper right quadrants were assumed to be apoptotic. (bioz.com)
  • A, Biomarker response data are graphed for anisomycin-exposed TK6 cells versus concentration. (nih.gov)