• tubules traveling from the cortex to the medulla with a similar appearance as proximal convoluted tubules. (histologyguide.com)
  • Mainly the proximal convoluted tubules are affected. (greek.doctor)
  • The nephron is made of 2 main parts: the renal corpuscle and the renal tubule. (innerbody.com)
  • The nephron consists of a glomerulus and a series of tubules ( Figure 1.2 ). (abdominalkey.com)
  • Tubules are lined by a continuous layer of epithelial cells, each of which possesses characteristic morphology and function depending on its location in the nephron. (abdominalkey.com)
  • The S3 segment of the proximal tubule, which maintains the delicate balance between high O 2 demand and low basal O 2 tension in the corticomedullary region, is the portion of the nephron most vulnerable to ischemia (Parker et al. (cellphysiolbiochem.com)
  • The proximal convoluted tubule is the portion of the nephron that attaches to the collecting duct. (studyhubpro.com)
  • The ascending limb drains urine into the distal convoluted tubule. (wikipedia.org)
  • During the maintenance phase, renal tubule injury is established, the GFR stabilizes at the level well below normal, and the urine output is low or absent. (medscape.com)
  • A series of tubes called the renal tubule concentrate urine and recover non-waste solutes from the urine. (innerbody.com)
  • The renal tubule carries urine from the glomerular capsule to the renal pelvis. (innerbody.com)
  • The tubule cells that line the proximal convoluted tubule reabsorb much of the water and nutrients initially filtered into the urine. (innerbody.com)
  • Urine next passes through the loop of Henle, a long straight tubule that carries urine into the renal medulla before making a hairpin turn and returning to the renal cortex. (innerbody.com)
  • Urine is formed by glomerular filtration and modified by the tubules, leaves the collecting ducts and drains sequentially into the calyces, renal pelvis, ureter, and finally into the bladder. (abdominalkey.com)
  • Although urine is finally modified in subsequent tubules, the proximal tubule is the main site for both NaCl and NaHCO 3 reabsorption. (cellphysiolbiochem.com)
  • This causes the proximal tubules to be unable to reabsorb sodium, meaning that more sodium reaches the distal tubules. (greek.doctor)
  • The intercalated cells of the distal tubule secrete hydrogen ions to reabsorb bicarbonate from the tubular fluid. (neetprep.com)
  • It indicates the tubules in the kidney nephrons to reabsorb salt while secreting or removing potassium. (ewaterpurifier.com)
  • Angiotensin I is converted to Angiotensin II with the substance called renin in the distal renal tubules of the kidneys. (triadofhealth.net)
  • Lasix is not an ideal drug because kidneys adapt to it by increasing proximal and distal tubule sodium retention, so when stopped rebound salt and water retention can continue for weeks, and swelling exceed what was there before the drug was ever taken. (uchicago.edu)
  • Aldosterone, the significant mineralcorticoid, stimulates the cells of the distal convoluted tubules of the kidneys to lower re-absorption of potassium as well as rise re-absorption of salt. (ewaterpurifier.com)
  • From the distal end of each ovary arises a thicker, wider and twisted oviduct, with a similar wall as that of the former and a lumen instead of solid cytoplasmic rachis. (wandofknowledge.com)
  • About 85% of the filterate formed is reabsorbed in a constant, unregulated fashion by the proximal convoluted tubule and descending limb of Henle's loop, called mandatory reabsorption. (apboardsolutions.guru)
  • As I shall show later on, lasix and lisinopril could have raised her risk for kidney damage from crystals, the former because of increased proximal tubule reabsorption , the latter because of reduced glomerular filtration rate . (uchicago.edu)
  • By depleting the body of sodium and water, these drugs would also raise proximal tubule reabsorption and lower glomerular filtration. (uchicago.edu)
  • There appears to be no direct or indirect coupling between sodium and chloride or bicarbonate reabsorption in the distal colon. (veteriankey.com)
  • Active chloride reabsorption and bicarbonate secretion occur in the distal colon. (veteriankey.com)
  • At the far end of the glomerular capsule, opposite the glomerulus, is the mouth of the renal tubule. (innerbody.com)
  • Salt moves out of the tubule and into the interstitium due to osmotic pressure created by the countercurrent system. (wikipedia.org)
  • Intrinsic ARF (40% of ARF cases) is the result of structural damage to the renal tubules, glomeruli, interstitium, or renal vasculature. (medscape.com)
  • Many diseases don't primarily affect the glomeruli but rather the tubules and interstitium. (greek.doctor)
  • This increases the backward pressure in the tubules, which forces filtrate to leak through the damaged tubules and back into the interstitium, a process called backleak . (greek.doctor)
  • At the junction of the thick ascending limb and the distal convoluted tubule are a subset of 15-25 cells known as the macula densa that are part of renal autoregulation through the mechanism of tubuloglomerular feedback. (wikipedia.org)
  • Especially the straight segment of the proximal tubule and the straight segment of the distal tubule (the thick ascending limb) are vulnerable to ischaemic damage. (greek.doctor)
  • A small difference is that it is the convoluted segment of the proximal tubule which is most susceptible to toxic damage. (greek.doctor)
  • have suggested that the pronephric duct as described traditionally may consist of subregions which are analogous to portions of the tubule segment of mammalian and other fish nephrons. (zfin.org)
  • 2015). Based on this theory, the reversed mode of NCX in proximal tubules, particularly the S3 segment, is required. (cellphysiolbiochem.com)
  • the thick portion is also known as the distal straight tubule, in contrast with the distal convoluted tubule downstream. (wikipedia.org)
  • Ischaemic ATN is characterised histologically by lesions in the straight portions of the proximal tubule and ascending thick limbs. (greek.doctor)
  • Distal part of testis continues into a short and thick twisted tube, the vas deferens. (wandofknowledge.com)
  • cross-sections with simple cuboidal to columnar epithelium similar to the respective convoluted tubule. (histologyguide.com)
  • Which of the following three parts of the renal tubule is formed by cuboidal epithelial cells bordered by dense microvilli? (studyhubpro.com)
  • When the body becomes hypovolemic, aldosterone goes to the distal convoluted tubule in order to activate the receptor to draw in sodium. (bassamzahid.com)
  • The functional significance of the Na + /Ca 2+ exchanger (NCX) in basolateral membranes in the proximal tubule remains controversial. (cellphysiolbiochem.com)
  • 1989), however, suggested that there is no NCX in basolateral membranes in proximal tubules but that instead, intracellular calcium pools within the mitochondria and elsewhere contribute to Na + /Ca 2+ exchange. (cellphysiolbiochem.com)
  • The localization of NCX in basolateral membranes of proximal tubules is also controversial. (cellphysiolbiochem.com)
  • 3. All of the filtered bicarbonate is normally reabsorbed in the first half of the distal tubule. (neetprep.com)
  • The seminiferous tubules are lined with germ cells that produce sperm and nutrient fluid. (medscape.com)
  • Despite the nomenclature, frank necrosis of tubule cells is relatively inconspicuous in ischemic ATN, whereas it can be more extensive in heavy metal-induced nephrotoxic ATN. (medscape.com)
  • Through this strip run the terminal portions of the proximal tubules, where water extraction and oxalate secretion create highest supersaturations. (uchicago.edu)
  • The cells of the distal convoluted tubule are crowded in the region where distal convoluted tubule makes contact with afferent arteriole. (apboardsolutions.guru)
  • Black circles highlight proximal tubules filled with crystals, clear, sharp edged, and obviously different from cells. (uchicago.edu)
  • It is usually simple, both on the outer edge and at its distal extremity. (ordovicianatlas.org)
  • 7) What are the smallest (and most distal) structures that remain a component of the conducting zone in the respiratory tract? (subjecto.com)
  • In these spaces, the numerous lobules of glandular structures (the minute but long and highly coiled seminiferous tubules) are housed. (medscape.com)
  • The epididymal head overhangs the upper pole of the testis, receives the seminal fluid from the ducts of the testis (which pierce the upper portion of the mediastinum), then allows the passage of the sperm into the distal portion of the epididymis. (medscape.com)
  • The force of the heart filters water and salts out of the capillaries into the tubule of the nephrons. (uchicago.edu)
  • lower scores corresponded to fewer debris and higher number of open tubules. (researchgate.net)
  • Each ovary of Ascaris is a long, thread-like, much twisted and blind tubule. (wandofknowledge.com)
  • Pathologically, ATN is characterized by varying degrees of tubule cell damage (see Pathophysiology) and by cell death that usually results from prolonged renal ischemia, nephrotoxins, or sepsis. (medscape.com)
  • Renal tubule cell damage begins to evolve (but is not yet established) during this phase. (medscape.com)
  • Accordingly, to employ this adhesive system, it is necessary the previous treatment of the surface to be restored through phosphoric acid 10 , to open the dentinal tubules and to increase the contact surface, therefore enabling a better retention of the restorative material 19 . (bvsalud.org)
  • The rectangular to subcircular outline is truncated by a straight hinge line. (ordovicianatlas.org)
  • An angle bisector of a triangle is a straight line through a vertex which cuts the corresponding angle in half. (co.ke)
  • It is the distal most zone, where gametocytes separate from rachis and undergo maturation to form gametes. (wandofknowledge.com)
  • A highly educated woman, presently early middle age, had a form of Roux en Y as noted on the figure. (uchicago.edu)
  • The tubules perform a lot of ATP-dependant transport and therefore have a large requirement for perfusion. (greek.doctor)
  • Specimens of Orthis calligramma from Gotland, show openings of oblique tubules on the external surface, always situated upon the keels of the costae. (ordovicianatlas.org)
  • The efferent arterioles separate into the peritubular capillaries that surround the renal tubules. (innerbody.com)