• Centrin can be found in the transitional region of the axoneme, the bridge between the nucleus and the basal body, and both the proximal and distal fibres connecting the two basal bodies. (prospecbio.com)
  • Here we show the differentiation of patient specific iPSCs derived from a patient with SFTPB deficiency into lung organoids with mesenchymal and epithelial cell populations from both the proximal and distal portions of the human lung. (nature.com)
  • Although many differentiation protocols in the literature have been successful in mimicking lung development from stem cells, there has not been an examination of how a specific mutation impacts the differentiation process including its effects on the early endoderm, as well as the proximal and distal lung epithelial cell populations in the lung organoids. (nature.com)
  • Basal striations develop in proximal and distal tubules as an alignment of mitochondria, the result of what appears to be progressive interlocking of adjacent fluted cells. (rupress.org)
  • Cilia, essential motile and sensory organelles, have several compartments: the basal body, transition zone, and the middle and distal axoneme segments. (pasteur.fr)
  • We show that defects in the distal segment dimensions are associated with motile and sensory deficiencies of cilia. (pasteur.fr)
  • Centrioles can be transformed into basal bodies which give raise to cilia and flagella. (lifeeasy.org)
  • The basal bodies give rise to flagella and cilia. (byjus.com)
  • OCRL1 has been localized to the trans -Golgi network and various compartments of the endocytic pathway (traffic), where it is found in the clathrin-coated pits, clathrin-coated vesicles, variable functioning endosomes (early, signaling, recycling), and the basal body of primary cilia. (medscape.com)
  • In premitotic cells p210 was located in a fibrous layer at the distal end of nascent basal bodies, which was perforated by the outgrowing axoneme. (lookformedical.com)
  • Primary cilium consists of the basal body (mother centriole anchored to the plasma membrane via set of appendages at its distal end), the transition zone (a specialized compartment implicated in targeting and sorting proteins in/out of cilium), and the axoneme ( a membrane enclosed, microtubule-based structure protruding from the cell out). (cajaneklab.com)
  • We have previously shown that primary ciliogenesis in cultured human astrocytes and synoviocytes proceeds through stages beginning with the formation of a membrane bound vesicle at the distal end of the basal body (here referred to as stage 1) followed by the establishment and growth of a 9+0 ciliary axoneme [ 2 , 3 ]. (biomedcentral.com)
  • A monoclonal antibody raised against purified flagellar basal apparatuses from the green flagellate Spermatozopsis similis reacted with a protein of 210 kDa (p210) in western blots. (lookformedical.com)
  • flagellar basal-body rod protein FlgF [Ensembl]. (ntu.edu.sg)
  • Flagella basal body rod protein, Flagellar basal body rod FlgEFG protein C-terminal [Interproscan]. (ntu.edu.sg)
  • Flagellar basal body. (ntu.edu.sg)
  • In addition, the centriole component of the centrosome can function as a basal body that organizes the formation of a cilium while in many cases the associated PCM continues to operate as a cytoplasmic MTOC. (biomedcentral.com)
  • Most vertebrate cells contain a single non-motile primary cilium that is assembled in a step-wise manner from the distal end of a mature centriole within the centrosome. (biomedcentral.com)
  • The basal granule of father was colubrine and there were less starch grains. (eudic.net)
  • and ( c ) basal granule. (pharmacy180.com)
  • In the hippocampus, the CA1 neurons contain two distinctive regions that receive excitatory synaptic inputs: the perforant path (PP) through the apical dendritic tuft (500-750 μm from soma) and the Schaffer-collateral (SC) through the basal and apical dendrites (250-500 μm from soma). (stackexchange.com)
  • Stratum Oriens represents basal dendrites that are close to the cell body, stratum Radiatum apical trunks, and stratum Lacunosum-Moleculare the apical tufts. (stackexchange.com)
  • The apical cell and basal cell act as the ancestor cells of frond and rhizoid. (eudic.net)
  • metapleuron with confused fine rugulose sculpturing over anterior 1/5 plus distal 2/5, dorsal and distal edge with few small short transverse ridges, no medial pit present, remainder nitid. (plazi.org)
  • The right middle lobe bronchus divides into lateral and medial segmental bronchi, and the right lower lobe bronchus divides into the superior, medial basal, anterior basal, lateral basal, and posterior basal segmental bronchi. (medscape.com)
  • two small spineless dorsal fins, close together, towards posterior part of body and originating behind pelvic fin origin. (mnhn.fr)
  • a basal body situated just posterior to the nucleus. (eudic.net)
  • However, bands might be present in a more or less faint condition on the anterior portion of the body in some adults of typically striped species, and stripes tend to fade or disappear in the posterior part of the body of some adult striped forms. (dadospdf.com)
  • The lower lobe bronchus branches into superior, anteromedial basal, lateral basal, and posterior basal segmental bronchi. (medscape.com)
  • begingroup$ If we assign the cell body, or more precisely the stratum pyramidale, at $0$, then stratum oriens is to its dorsal side and stratum radiatum on its ventral side. (stackexchange.com)
  • The bifossatus group has a banded pattern in the adult, eight supralabials, a shorter snout, and 15 dorsal scale rows in the middle of the body, whereas the other three groups have a striped or unicolor pattern in adults, nine supralabials, a longer snout, and 17 dorsal scale rows. (dadospdf.com)
  • The dorsal skin of the body has flattened tubercles and dispersed white spicules that are uniformly distributed and not very prominent in females while they are more elevated in males. (amphibiaweb.org)
  • In this study we show in mice that Ftm (Rpgrip1l) is located at the ciliary basal body. (silverchair.com)
  • Ultrasonic coagulation of the ciliary body with pinpoint precision using high intensity focused ultrasound (HIFU) enables significant reduction of aqueous inflow and intraocular pressure (IOP). (touchophthalmology.com)
  • Results from animal studies and from a clinical pilot study of patients with refractory glaucoma indicate that ultrasonic coagulation of the ciliary body using HIFU delivered by a circular miniaturised transducer is an effective and well-tolerated method of reducing IOP. (touchophthalmology.com)
  • Apart from eye drops and surgery, another therapy used to treat refractory glaucoma is ciliary body destruction. (touchophthalmology.com)
  • Several energy sources and different techniques for destroying ciliary body processes have been studied by researchers. (touchophthalmology.com)
  • How to Assess the Motor System Motor weakness can be due to dysfunction in the corticospinal tract, basal ganglia, spine, peripheral nerves, or muscle. (msdmanuals.com)
  • Two GW/P bodies as marked by GW182 and hAgo2 colocalized to the basal body of primary human astrocytes as well as human synoviocytes during interphase and specifically with the distal end of the basal body in the pericentriolar region. (biomedcentral.com)
  • b Possible evolutionary transition from bilateral symmetry to pentameral symmetric body plan suggested by paleontological studies61. (echinobase.org)
  • mesopterygium The median, elongated basal cartilage of the pectoral fins in Elasmobranchii, Holocephali and primitive Teleostomi. (eudic.net)
  • Flagella basal body. (ntu.edu.sg)
  • It has been amply demonstrated and established that the meticulous growth of the flagella invariably takes place by the careful addition of the flagellin subunits at the distal end after being drifted through from the cytoplasm, obviously via the hollow core of the very flagellum. (pharmacy180.com)
  • In each of the six heavy chains (dynein a, b, c, d, e, and g), the N-terminal tail extends from the distal side of the ring. (rupress.org)
  • For resectable pancreatic body or tail tumors, EUS-FNA should be carefully performed to prevent needle tract seeding and intraoperative as well as postoperative assessment for gastric wall metastasis is mandatory. (biomedcentral.com)
  • Interestingly, both the basal granules and the hook essentially contain certain specific proteins that are antigenically distinct from the flagellin ( i.e., the protein of the filament). (pharmacy180.com)
  • At birth there are dense irregular cytoplasmic inclusions presumed to be lipide in renal cells, the cytoplasmic granules of Palade are abundant, and there are large round bodies in the cells of the proximal tubules. (rupress.org)
  • We suppose that p210 is involved in linking basal bodies to the plasma membrane, which is an important step during ciliogenesis. (lookformedical.com)
  • Since it is technically challenging to examine the two centrosomal GW/P bodies in isolation, we investigated the potential relationship between the global population of GW/P bodies and primary ciliogenesis. (biomedcentral.com)
  • While the middle segment contains doublet microtubules (incomplete B-tubules fused to complete A-tubules), the distal segment contains only A-tubule extensions, and its existence requires coordination of microtubule length at the nanometer scale. (pasteur.fr)
  • A postciliary ribbon and other microtubules fan out from it's basal bodies. (ucsd.edu)
  • Mathematical modeling of the primary cilium as a fluid-structure interaction problem highlights the importance of basal anchorage and the anisotropic moduli of the microtubules. (aimspress.com)
  • A 210 kDa protein is located in a membrane-microtubule linker at the distal end of mature and nascent basal bodies. (lookformedical.com)
  • Using a polyclonal antibody (anti-p210) raised against the C-terminal part of p210, it was shown that the protein was highly enriched in the basal apparatuses. (lookformedical.com)
  • During deflagellation the protein remained at the basal body but we observed changes in its distribution, indicating that p210 partially moved to the tip of the basal body. (lookformedical.com)
  • Flagellar hook protein FlgE (Distal rod protein). (ntu.edu.sg)
  • Flagellar hook-basal body complex protein FlgG1. (ntu.edu.sg)
  • Distal rod protein [Ensembl]. (ntu.edu.sg)
  • The distal segment accommodates key functions, including cilium assembly and sensory activities. (pasteur.fr)
  • In most cells, the centriolar component of the centrosome can function as a basal body supporting the formation of a primary cilium, a non-motile sensory organelle that monitors information from the extracellular matrix and relays stimuli into the cell via associated signaling pathways. (biomedcentral.com)
  • Cross sections of overlapping microtubular ribbons arising from the dikinetids are seen in the ridges next to the basal body. (ucsd.edu)
  • The fingers are long, do not have dermal ridges, and are round at the distal end. (amphibiaweb.org)
  • Computed tomography (CT) scan revealed inflammatory changes in the left lung field, and incidentally, a 15-mm hypovascular mass was detected in the pancreatic body. (biomedcentral.com)
  • The area of the lung that is distal to a terminal bronchiole is termed the acinus. (medscape.com)
  • 89. The prickly shark Echinorhinus cookei has thorn-like denticles on body which are moderately large (single denticles up to about 4mm in basal diameter in adults), numerous, regularly distributed, with scalloped basal margins, and never fused into compound plates. (mnhn.fr)
  • The fundamental structure of a coral polyp is a cylindrical sac composed of two layers of epithelia: the surface body wall , which forms the outermost barrier between the organism and its surroundings, and the basal body wall , which anchors the polyp to its skeleton. (noaa.gov)
  • y un patrón de rayas en la sección ventral de la aleta caudal con una línea marginal negra muy estrecha, intermitente o incluso ausente. (scielo.br)
  • GW/P bodies are found throughout the cytoplasm and previously published live cell imaging data suggested that in a malignant cell type (U2OS), two GW/P bodies reside at the centrosome during interphase. (biomedcentral.com)
  • This study confirms and extends a previously published report that GW/P bodies reside at the centrosome in U2OS cells and documents that GW/P bodies are resident at the centrosome in diverse non-malignant cells. (biomedcentral.com)
  • When the legs are adpressed along the body, the external metatarsal tubercle reaches the median level of the orbit or further. (amphibiaweb.org)
  • He forwarded the germ layer theory which states that "various structures of the body arise from the same germ layers in different species of animals" . (biologydiscussion.com)
  • We show that three conserved proteins, two of which are mutated in the ciliopathy Joubert syndrome, determine the geometry of the distal segment, by controlling the positions of specific microtubule ends. (pasteur.fr)
  • Our observations suggest that abnormalities in distal segment organization cause a subset of Joubert syndrome cases. (pasteur.fr)
  • body green with thin pale band across each abdominal segment. (bugguide.net)
  • In the ascidian Ciona intestinalis , basal body parts regenerate distal structures but distal body parts do not replace basal structures. (biologists.com)
  • The large round bodies in the proximal tubules consist of an amorphous material and contain concentrically lamellar structures and mitochondria. (rupress.org)
  • The large round bodies disappear from the proximal tubules of infant mice during the first week after birth, but the concentric lamellar structures may be found in adult mice. (rupress.org)
  • flagellar component of cell-distal portion of basal-body. (ntu.edu.sg)
  • We also show the presence of normal lamellar bodies and the secretion of surfactant into the cell culture medium in the organoids of lentiviral infected cells. (nature.com)
  • Background: To distinguish a basal cell carcinoma (BCC) from a trichoepithelioma (TE) can be difficult even for an experienced dermatopathologist. (eudic.net)
  • Objective To study the observation in electronic dermatoscope to the papule or nodular pigmented basal cell carcinoma(pBCC) and the significance of its clinical diagnosis. (eudic.net)
  • Case 2: A 70-year-old man was incidentally detected with a pancreatic body mass on a CT scan as part of his follow-up for recurrence of basal cell carcinoma. (biomedcentral.com)
  • The collecting ducts develop tight pleating of the basal cell membranes, and dark cells containing numerous small cytoplasmic vesicles and microvilli appear. (rupress.org)
  • Retractor muscles on mesenteries near the body wall allow the polyp to contract and extend. (noaa.gov)
  • Also, it supports the weight of the body from the vertebral column. (msudenver.edu)
  • In addition, the inflow from the renal veins can be seen at the level of the L1 vertebral body. (medscape.com)
  • After metamorphosis, however, ascidian juveniles and adults show impressive capacities for regeneration of injured body parts. (biologists.com)
  • During the first half of the cycle, estrogen dominates and causes the body to produce more cervical mucus , which creates a lower, more stable BBT. (premom.com)
  • In fact, the particular structure of the basal body comprises of a small central rod inserted strate-gically into a system of rings as illustrated in Fig. 2.10 below. (pharmacy180.com)
  • After bisection across the mid-body, apoptosis occurred only in the regenerating basal fragments, although both fragments contained a part of the branchial sac, suggesting that apoptosis is unilateral at the wound site and the presence of branchial sac stem cells is insufficient for regeneration. (biologists.com)
  • The bronchial mucosa is made of pseudostratified ciliated columnar epithelium with goblet cells and basal cells. (medscape.com)
  • During embryonic development, the skeleton remains primarily cartilaginous to form the basic structural components and framework of the body. (msudenver.edu)
  • The pair of basal bodies have a proximal cartwheel and a dense septum (not found in most bbs) just distal to the cartw. (ucsd.edu)
  • The pair of basal bodies have a proximal cartwheel and a dense septum (not found in most bbs) just d. (ucsd.edu)
  • There are also some chemoreceptive hairs among them, however, which are mostly found on the distal sections of walking legs and pedipalps and recognized by the steeper angle to the cuticular surface and often a slightly S-shaped hair shaft. (scholarpedia.org)
  • Evolutionarily conserved echinoderm stages and potential involvement of pitx signal in pentameral body plan development.a Mid-embryonic conservation found in echinoderm species. (echinobase.org)
  • consisting of one unpaired ambulacrum (1) and two ambulacra with a distal bifurcation (2&3, 4&5) and a single unpaired ambulacrum (1). (echinobase.org)
  • Bayesian length-weight: a=0.00363 (0.00139 - 0.00949), b=3.13 (2.90 - 3.36), in cm total length, based on LWR estimates for this (Sub)family-body shape (Ref. 93245 ). (mnhn.fr)
  • The body length is measured from the apex of the head to the end of the forewings and is given in millimeters (mm). (pensoft.net)
  • Body length = 2.1 mm. (plazi.org)
  • The body of Atelopus mittermeieri is robust and the snout-vent length is 32.99 - 33.36 mm for males and 41.33 - 44.95 mm for females. (amphibiaweb.org)
  • The strength of specific muscle groups is tested against resistance, and one side of the body is compared with the other. (msdmanuals.com)
  • In each species, the developmental phase in which pentameral body plan establishment begins is colored in gray. (echinobase.org)
  • The human physiologic response to cold exposure is to retard heat loss and preserve core body temperature, but this response may not be sufficient to prevent hypothermia if heat loss is prolonged. (health.mil)
  • The strontium content of the human body is approximately 4.6 ppm by weight, 99% of which is localized in bones and teeth. (cdc.gov)
  • Located at the distal end of this region is the polyp's mouth, oral disk, and ring of tentacles. (noaa.gov)
  • This BBT drop is due to the decrease in progesterone levels in your body, which occurs when you do not conceive during that menstrual cycle. (premom.com)
  • 50% of mRNA that occurs within GW/P bodies. (biomedcentral.com)
  • Volunteers will be randomized for LPS injections proximal or distal on the lower forearms. (who.int)
  • Further, unlike in other animal groups, the most conserved developmental stages were not at the body plan establishing phase, and genes normally involved in bilaterality appear to function in pentameric axis development. (echinobase.org)
  • p210 can be used as a marker to determine basal body position, orientation (parallel or antiparallel) and number in S. similis by indirect immunofluorescence. (lookformedical.com)