• These techniques, including magnetic resonance imaging (MRI), positron emission tomography (PET), electroencephalogram (EEG), and magnetoencephalography (MEG), have been used to study abnormal brain functions and structures in patients with different types of headaches. (biomedcentral.com)
  • The primary methods used by investigators in this Branch are PET (positron emission tomography) and NMR (nuclear magnetic resonance). (nih.gov)
  • During his PhD, he used neuroimaging modalities - including structural magnetic resonance imaging (MRI), functional MRI, diffusion tensor imaging, and positron emission tomography - to study the possible risk of Alzheimer's disease following trauma in the form of traumatic brain injury and post traumatic stress disorder (PTSD). (edu.au)
  • We use imaging techniques including functional and structural magnetic resonance imaging (MRI), electroencephalogram (EEG), and positron emission tomography (PET) to inspect brain changes in blood-oxygen level dependent function, white matter microstructure, electrical conductivity, glucose metabolism and receptor availability. (mssm.edu)
  • Funding from the HBHL Core Facilities Grant is essential, as it allows partial coverage of the cost of several service contracts that maintain the BIC's technological and methodological platforms, including the Magnetic Resonance Imaging (MRI) Unit, Preclinical MRI Unit, the Positron Emission Tomography Unit and the Radiochemistry Unit. (mcgill.ca)
  • A variety of imaging modalities, including structural and functional magnetic resonance imaging (MRI) and positron emission tomography (PET) studies of cerebral metabolism, have shown characteristic changes in the brain of patients with Alzheimer disease in prodromal and even presymptomatic states. (medscape.com)
  • Second-tier imaging with molecular methods, preferably with fluorodeoxyglucose positron emission tomography (FDG-PET) (or single-photon emission CT [SPECT] if PET is unavailable), can provide greater diagnostic specificity. (medscape.com)
  • Brain 2023;146:50-64. (reliasmedia.com)
  • Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRß, a marker of blood brain barrier breakdown, in older adults Res Sq. 2023 Mar 07. (usc.edu)
  • She completed a postdoctoral fellowship at the Neuro and Douglas Research Centre between 2018 and 2023, where she studied multimodal brain-cognition associations in psychosis and digital cognitive health. (mcgill.ca)
  • This meta-analysis aims to comprehensively reassess brain activation and connectivity in BD in order to identify replicable differences that converge across and within resting-state, cognitive, and emotional neuroimaging experiments. (nature.com)
  • In our projects, we investigate how different regions of the brain interact with one another, both in healthy people and those suffering from neurological diseases, particularly focusing on connectivity and reorganization. (unimedizin-mainz.de)
  • The goal is to improve the clinical effect and reduce the possible side effects after an optimized implantation of the stimulation electrodes on the basis of the connectivity determined using magnetic resonance imaging. (unimedizin-mainz.de)
  • Structural magnetic resonance tomography data are evaluated using diffusion-weighted imaging techniques, probabilistic tractography (FSL, SPM, VBM) as well as T1 images (Freesurfer, SPM) to perform network characterizations (BCT, NBS) and connectivity analyses. (unimedizin-mainz.de)
  • and voxel-based, whole-brain functional magnetic resonance imaging (fMRI) analysis and brain connectivity-to the understanding of the underlying causes contributing to the susceptibility for addiction and wide heterogeneity in addiction treatment outcomes. (ispa.pt)
  • Cortical thickness, mean diffusivity, and fractional anisotropy were estimated at each of 308 cortical regions, as well as functional and structural connectivity between each pair of regions. (maastrichtuniversity.nl)
  • RESULTS: In both principal studies, the most informative metric was functional MRI connectivity: The areas under the receiver operating characteristic curve were 88% and 76%, respectively. (maastrichtuniversity.nl)
  • CONCLUSIONS: ML most accurately distinguished cases from controls by a replicable pattern of functional MRI connectivity features, highlighting abnormal hubness of cortical nodes in an anatomical pattern consistent with the concept of psychosis as a disorder of network development. (maastrichtuniversity.nl)
  • The authors used region of interest (ROI)-to-ROI analysis to investigate functional connectivity patterns in patients with post-traumatic stress disorder (PTSD) and its dissociative subtype compared with healthy controls. (nature.com)
  • Aberrant functional connectivity between reward and inhibitory control networks in pre-adolescent binge eating disorder Psychol Med. (usc.edu)
  • Functions including memory, perception, learning, spatial cognition, attention, emotion processing and motor skills show degree of hemispheric specialization, and disrupted brain anatomy and more recently connectivity asymmetry has been associated with neuropsychiatric disorders such as schizophrenia. (cas.cz)
  • The outstanding challenges include relating structural and functional symmetries, bridging the gap between global symmetries (such as bilateral symmetry) and local symmetries, providing normative description of brain symmetries, and relation of inter-individual differences in brain connectivity (a)symmetry to cognitive and clinical characteristics such as in aberrant lateralization in schizophrenia. (cas.cz)
  • Frustrated with the limits of inference based on behavioral and mainstream neural measures, he worked to create an alternative approach to discovering the functional architecture of cognitive processes by developing a functional neuroanatomical model of lexical representation (link to dual lexicon paper section), and a high spatiotemporal resolution processing stream for the data-driven recovery of directed connectivity in (link to GPS section) rapidly evolving, large distributed processing networks. (harvard.edu)
  • Their new study, published in Nature Mental Health , represents the first large-scale analysis of its kind in which researchers analyzed functional network connectivity (FNC) across scans and identified associations with a diverse range of health measures in children. (futurity.org)
  • Researchers say that brain functional connectivity derived from functional magnetic resonance imaging (fMRI) is commonly used as a potential blueprint for adults. (futurity.org)
  • Principal investigator Zening Fu says the study demonstrates that functional connectivity variability can predict a wide range of children's behavior, including cognition, mental health, and sleep conditions. (futurity.org)
  • Most previous fMRI studies believe that resting-state functional connectivity can provide a fingerprint of an individual, and that variability in connectivity is due to noise or other confounding effects," says Fu. (futurity.org)
  • FNC stability in our present work is defined as the variability or changes in the resting-state functional connectivity across scans (measurements)," Fu says. (futurity.org)
  • That is, if a subject has been collected using resting-state fMRI scans multiple times, the functional connectivity estimated using each fMRI scan should be different, even if they are from the same subject. (futurity.org)
  • In a second study, published in Biological Psychiatry , research conducted at the TReNDS Center and led by Weizheng Yan finds that functional network connectivity, which steadily reconfigures over time, potentially contains abundant information to assess psychiatric risks. (futurity.org)
  • Much of the work in cognitive neuroscience is shifting from a focus on single brain regions to a focus on the connectivity between multiple brain regions. (researchgate.net)
  • These inter-regional connectivity patterns contribute to a wide range of behaviors and are studied with models of functional integration. (researchgate.net)
  • Yet, considerable variability exists in the connectivity patterns between different brain areas, potentially producing reliable group differences. (researchgate.net)
  • Functional connectivity (FC) analysis is an approach that measures functional integration in brains. (unm.edu)
  • Secondly, we applied graph analysis on functional network connectivity (FNC) to differentiate BD and MDD during resting-state. (unm.edu)
  • Although the rising evidences about its possible role in the treatment of many neurological and psychiatric conditions exist, no evidences exist about brain functional connectivity substrates underlying tDCS response. (frontiersin.org)
  • Brain connectivity can be divided into functional connectivity, where spontaneous temporal synchronisations between brain regions are measured using fMRI with subjects scanned at rest, and structural connectivity, measured using diffusion MRI (dMRI), which images the physical connections between brain regions based on how water molecules diffuse within white matter tracts. (biorxiv.org)
  • The primary objectives of the project are to 1) Map the development of self-regulation functions and associated brain activity across adolescence, 2) Probe how this development is related to changes in brain structure and structural connectivity, 3) Test how early life influences and traits are associated with individual differences in adolescents' self-regulation functions, and 4) Examine the relevance of these functions for mental health and school performance. (fluxsociety.org)
  • Functional Connectivity Disruption in Subjective Cognitive Decline and Mild Cognitive Impairment: A Common Pattern of Alterations. (humanconnectome.org)
  • Functional connectivity (FC) alterations represent a key feature in Alzheimer's Disease (AD) and provide a useful tool to characterize and predict the course of the disease. (humanconnectome.org)
  • Age-related differences in function and structure of rSMG and reduced functional connectivity with DLPFC explains heightened emotional egocentricity bias in childhood. (mpg.de)
  • We computed the activity maps unique to switch vs. stay trials and all switch dimensions, then evaluated functional connectivity under these switch conditions by computing the pairwise mutual information functional connectivity (miFC) between regional timeseries. (imperial.ac.uk)
  • Muthuraman M*, Bange M*, Koirala N, Ciolac D, Pintea B, Glaser M, Tinkhauser G, Brown P, Deuschl G, Groppa S (2020) Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in cortico-subcortical networks in Parkinson's disease patients. (unimedizin-mainz.de)
  • 2020 ) Image acquisition and quality assurance in the Boston Adolescent Neuroimaging of Depression and Anxiety study. (neurotree.org)
  • Traumatic brain injury and post-traumatic stress disorder are associated with persistent white matter disruption in Vietnam War veterans , Biological Psychiatry Australia, 19-20 October 2020, Sydney/Virtual. (edu.au)
  • Fritze S, Topor CW, Kubera KM, Northoff G, Schmitgen MM, Wolf RC*, Hirjak D* (2020) Midbrain alterations contribute to motor catatonic symptoms in schizophrenia spectrum disorders. (uni-heidelberg.de)
  • Fritze S, Sambataro F, Kubera KM, Bertolino AL, Topor CE, Wolf RC*, Hirjak D* (2020) Neurological Soft Signs in schizophrenia spectrum disorders are not confounded by current antipsychotic dosage. (uni-heidelberg.de)
  • Hirjak D, Rashidi M, Kubera KM, Northoff G, Fritze S, Schmitgen MM, Sambataro F, Calhoun VD, Wolf RC (2020) Multimodal MRI data fusion reveals distinct patterns of abnormal brain structure and function in catatonia. (uni-heidelberg.de)
  • A brain and body imaging extension will scan 100,000 participants by 2020, with brain imaging including three structural modalities, resting and task fMRI, and diffusion MRI 4 ( Supplementary Table 1 ). (biorxiv.org)
  • Recent brain imaging studies have adopted the cognitive neuroscience approach for studying the neural mechanisms of social influence. (hse.ru)
  • For her research, Camille Piguet Nemitz is particularly interested in using functional neuroimaging and cognitive neuroscience approaches to study cerebral networks of stress response as a marker of vulnerability to emotional regulation disorders. (unige.ch)
  • There, Goldstein will be a professor in the psychiatry department with a secondary appointment in the Friedman Brain Institute in the department of neuroscience. (bnl.gov)
  • She received a PhD in Neuroscience in 2018 from the University of British Columbia for her research on functional brain networks underlying cognitive biases and delusions in schizophrenia. (mcgill.ca)
  • A central challenge for neuroscience lies in relating inter-individual variability to the functional properties of specific brain regions. (researchgate.net)
  • Hirjak D, Meyer-Lindenberg A, Sambataro F, Fritze S, Kukovic J, Kubera KM, Wolf RC (2021) Progress in sensorimotor neuroscience of schizophrenia spectrum disorders: lessons learned and future directions. (uni-heidelberg.de)
  • Hirjak D, Meyer-Lindenberg A, Sambataro F, Wolf RC (2021) Sensorimotor neuroscience in mental disorders: Progress, perspectives and challenges. (uni-heidelberg.de)
  • His research involves development of techniques for the analysis of multimodal biomedical imaging data, in particular, for the use of fMRI data to inform the source estimation (inverse problem) of MEG and EEG. (harvard.edu)
  • Affiliated with the Montreal Neurological Institute (The Neuro) at McGill University, the McConnell Brain Imaging Centre (BIC) is a one-of-a-kind, multidisciplinary neuroimaging centre recognized internationally for its advances in the acquisition and analysis of multimodal imaging data, as well as for its groundbreaking discoveries related to structural, functional and molecular mechanisms of the healthy and diseased brain. (mcgill.ca)
  • Herein we report on a pilot study involving twelve participants with ALS and nine age-matched healthy controls who underwent high-resolution resting state functional magnetic resonance imaging at an ultra-high field of 7 Tesla. (biorxiv.org)
  • METHODS: One hundred and fourteen MDD patients and 74 healthy controls (HCs) underwent resting-state functional and perfusion magnetic resonance imaging (MRI) scans as well as overnight polysomnography examination to assess brain function and REM%, with 48 patients completing follow-up visits. (bvsalud.org)
  • Signs of brain disruption, potentiation and rewiring will be explored with resting-state functional MRI, magnetic resonance spectroscopy and multishell diffusion weighted imaging (DWI). (biomedcentral.com)
  • We retrospectively evaluated resting state functional Magnetic Resonance Imaging (fMRI) of 16 sub-acute and chronic MCS patients (6 tDCS responders) who successively received a single left dorsolateral prefrontal cortex (DLPFC) tDCS in a double-blind randomized cross-over trial. (frontiersin.org)
  • Careful evaluation and measurement of the phenotype and nature of sleep disturbance will continue to advance understanding of the biological bases of psychiatric disorders and the connections with sleep. (bvsalud.org)
  • Emotional dysregulation (ED) is a common symptom in several psychiatric disorders, including bipolar disorder, ADHD and borderline personality disorder. (unige.ch)
  • Researchers report new ways to accurately identify possible biomarkers in adolescent brains that can reliably predict cognitive developments and psychiatric issues. (futurity.org)
  • This study is quite exciting as it shows the promise of using advanced machine learning to identify brain patterns which might help us intervene early in children who are most at risk for cognitive or psychiatric problems ," says Calhoun, senior author of the study. (futurity.org)
  • As part of the study, researchers developed a brain-wide risk score (BRS), a novel FNC-based metric that contrasts the relative distances of an individual's FNC to that of psychiatric disorders versus healthy control references. (futurity.org)
  • The research team discovered that the BRS revealed a distinct, repeatable gradient of FNC patterns for each psychiatric disorder in over 8,000 unaffected teenagers, ranging from low to high risk. (futurity.org)
  • The Douglas-Bell Canada Brain Bank (DBCBB) currently houses over 3,500 brains from people with diverse psychiatric and neurological disorders (including schizophrenia, major depression, bipolar disorder, Alzheimer's disease and substance disorders) through special partnerships with research consortia. (mcgill.ca)
  • As the DBCBB contains tissue from psychiatrically healthy individuals and from those affected with psychiatric and neurological disorders, it allows for unique discoveries on the human brain and human illnesses, but also for research conducted in animals to be translated to humans. (mcgill.ca)
  • According to the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), postconcussion syndrome is given a diagnosis of either major or mild neurocognitive disorder (NCD) due to TBI. (medscape.com)
  • Ultimately, her research is concerned with understanding the cognitive underpinnings of multiscale neuropsychosocial markers in psychiatric disorders. (mcgill.ca)
  • Cognitive dysfunction is a key characteristic of psychiatric disorders, contributes to symptoms and poor outcomes, and is driven by brain dysconnectivity. (mcgill.ca)
  • Cognitive dysfunction can thus be considered a bridge between brain and behaviour in psychiatric disorders. (mcgill.ca)
  • Our results provide new insight into the genetic architecture of the brain with relevance to complex neurological and psychiatric disorders, as well as brain development and aging. (biorxiv.org)
  • Disease effects seen in MRI data have been identified in many neurological and psychiatric disorders such as Alzheimer's disease, Parkinson's disease, schizophrenia, bipolar disorder and autism 1 . (biorxiv.org)
  • Life After Mild Traumatic Brain Injury: Widespread Structural Brain Changes Associated With Psychological Distress Revealed With Multimodal Magnetic Resonance Imaging Biol Psychiatry Glob Open Sci. (usc.edu)
  • He is also Jim Turner Professor of Cognitive Disorders at Vanderbilt University School of Medicine and Professor of Psychiatry, Pharmacology, and Medicine. (vumc.org)
  • The time has come to ask if we have invented a science (psychiatry) that has little to do with reality, and to answer that, the creation of multicentric data bases is proposed, in which biological (not just brain based), social, personal, clinical, etc. variables are integrated, to finally obtain correlations that allow us a reclassification of brain pathology that would be useful to offer integral and personalized treatments. (bvsalud.org)
  • The simultaneous and synchronized video recording identifies clinical seizure activity along with electrophysiological activity on EEG, which helps to investigate, correlated haemodynamic changes in brain during seizures. (wikipedia.org)
  • In addition to our clinical work , scientific research plays an important role in the Section for Movement Disorders and Neurostimulation of the University Medical Center Mainz. (unimedizin-mainz.de)
  • Self-supervised learning is crucial for clinical imaging applications, g. (deepai.org)
  • Outcomes are compared before and after mindfulness practice using clinical assessments, biological markers and brain imaging. (unige.ch)
  • In conjunction with serial clinical examinations, electroencephalogram and functional magnetic resonance imaging may be helpful in predicting who will recover consciousness after an acute brain injury. (reliasmedia.com)
  • Prior studies have suggested that advanced imaging/EEG may reveal a cognitive-motor dissociation in which the physical examination may not show any clinical indication of consciousness, but advanced imaging/electrophysiological modalities suggest that consciousness may be present. (reliasmedia.com)
  • Most MRI/fMRI studies are carried out on the 3 and 7 Tesla magnets at the Functional Magnetic Resonance Imaging Core Facility or Clinical Center Radiology Department. (nih.gov)
  • All participants will undergo multimodal magnetic resonance imaging (MRI) as well as neuropsychological and clinical assessments at multiple time points before, during and after treatment. (biomedcentral.com)
  • Goldstein's research has focused on the brain-behavior relationships in human addiction and translating advances gained through this research to clinical treatment. (bnl.gov)
  • Transcranial magnetic stimulation (TMS) is a tool that is used regularly in experimental and clinical research, as well as for therapeutic and diagnostic purposes. (cas.cz)
  • I am applying the source estimation methods to experimental data in collaboration with several researches how are using MEG/EEG/fMRI to study cognitive functions in normal and clinical populations, including dyslexia and obsessive-compulsive disorder. (harvard.edu)
  • One should indirectly detect it by locating other relevant zones, which are involved in generating the epileptic disorder or relevant electrographical and clinical symptoms, such as the irritative zone (IZ). (veterinaryevidence.org)
  • My research aims to establish reliable biomarkers for clinical services to predict individual disease stages of brain disorders, monitor treatment responses and develop novel interventions. (researchgate.net)
  • Background: Early psychosis in first-episode psychosis (FEP) and clinical high-risk (CHR) individuals has been associated with alterations in mean regional measures of brain morphology. (researchgate.net)
  • Examination of variability in brain morphology could assist in quantifying the degree of brain structural heterogeneity in clinical relative to healthy control (HC. (researchgate.net)
  • We investigated evidence for advanced brain ageing in adult SZ patients, and whether this was associated with clinical characteristics in a prospective meta-analytic study conducted by the ENIGMA Schizoph. (researchgate.net)
  • Clinical characteristics with brain magnetic resonance imaging were evaluated in forty patients with NMOSD. (phoenixrising.me)
  • Stroke, or cerebrovascular accident (CVA), is a clinical term that describes a sudden loss of neurologic function persisting for more than 24 hours that is caused by an interruption of the blood supply to the brain (see the images below). (medscape.com)
  • Generally, the complexity and severity of a patient's clinical condition should dictate the selection of appropriate imaging procedures or treatments. (bvsalud.org)
  • Mental disorders such as schizophrenia (SZ), bipolar (BD), and major depression disorders (MDD) can cause severe symptoms and life disruption. (unm.edu)
  • The overall goal of the Branch is to further elucidate pathophysiological mechanisms associated with neuropsychiatric disorders, with the expectation that such knowledge will ultimately decrease the burden of these illnesses by helping guide the development and evaluation of improved therapeutics for these disorders. (nih.gov)
  • The Neuroimaging Section applies both PET and NMR imaging technologies to investigate the neurobiological bases of neuropsychiatric disorders. (nih.gov)
  • Other interests include treatment of depression and behavioral disturbances in the elderly, and development of effective novel agents for the treatment of neuropsychiatric disorders of the elderly. (vumc.org)
  • He obtained his PhD from the Queensland Brain Institute, the University of Queensland in 2021. (edu.au)
  • Exerceix, a més, com a director científic del Centre de Recerca Biomèdica en Xarxa de Salut Mental (CIBERSAM). (clinicbarcelona.org)
  • The position will be part of the Norwegian Centre for Mental Disorders Research (NORMENT), in collaboration with the PROMENTA Research Center. (fluxsociety.org)
  • Jag är även docent vid Karolinska Institutet (KI), anknuten till Aging Research Center vid KI, affilierad till Stockholm University Brain Imaging Centre (SUBIC), samt har en fakultetsposition vid Digital Futures som är ett tvärvetenskapligt forskningscentrum lokaliserat till Kungliga Tekniska Högskolan. (su.se)
  • Neuroimaging has revealed that migraine is linked to alterations in both the structure and function of the brain. (biomedcentral.com)
  • Thirdly, two functional measures, FNC and fractional amplitude of low frequency fluctuations (fALFF), were spatially overlaid to compare the FC and spatial alterations in SZ. (unm.edu)
  • Besides the morphological alterations, some authors suggested that the microstructural changes of the thalamus assessed by diffusion tensor imaging (DTI) could also be related to fatigue in the early stages of MS 23 . (phoenixrising.me)
  • Functional network alterations and their structural substrate in drug-resistant epilepsy. (mpg.de)
  • Comparison of group-level, source localized activity for simultaneous functional near-infrared spectroscopy-magnetoencephalography and simultaneous fNIRS-fMRI during parametric median nerve stimulation. (humanconnectome.org)
  • Functional near-infrared spectroscopy (fNIRS) is a noninvasive neuroimaging technique, which uses light to measure changes in cerebral blood oxygenation through sensors placed on the surface of the scalp. (humanconnectome.org)
  • I min forskning använder jag framför allt funktionell-magnetresonans-tomografi (fMRI), positron-emissions-tomografi (PET) och functional near-infrared spectroscopy (fNIRS) för att studera hjärnans funktion. (su.se)
  • use the functional near-infrared spectroscopy based cerebral blood flow imaging method to estimate the hemodynamic response function of each ROI, in order to study the brain networks that are activated during the processing of self-esteem related information [9]. (researchsquare.com)
  • Several NMR methods are also studied to measure molecular targets (magnetic resonance spectroscopy (MRS)), local neuronal activity (functional MRI (fMRI)), and brain structure (structural MRI). (nih.gov)
  • The Section on Magnetic Resonance Spectroscopy (MRS) develops and applies both high-resolution and in vivo MRS and imaging techniques. (nih.gov)
  • Numerous studies are under way to identify specific imaging markers for different types of dementia, including cerebral volumetric measurements, diffusion imaging, spectroscopy, very-high-field MRI scans of senile plaques, and PET scan markers of senile plaques. (medscape.com)
  • Assessment of brain metabolite correlates of adeno-associated virus-mediated over-expression of human alpha-synuclein in cortical neurons by in vivo (1) H-MR spectroscopy at 9.4 T. (lu.se)
  • Over the past few decades, neuroimaging research in Bipolar Disorder (BD) has identified neural differences underlying cognitive and emotional processing. (nature.com)
  • La seva unitat és una referència mundial en l'atenció, la investigació i la docència clínica sobre el trastorn bipolar i la depressió. (clinicbarcelona.org)
  • Major unipolar depressive disorder (MDD) and bipolar depressive disorder (BDD) are common and serious medical conditions that may lead to profound suffering, reduced quality of life, inability to work and increased risk of mortality ( https://www.who.int/news-room/fact-sheets/detail/depression ). (biomedcentral.com)
  • Neuroimaging experiments (using fMRI, PET, or arterial spin labeling) reporting whole-brain results in adults with BD and controls published from December 1999-June 18, 2019 were identified via PubMed search. (nature.com)
  • Then, I will present neuroimaging data from treatment-seeking adults with current DSM-5 Alcohol Use Disorder, providing new insights into why it is so difficult to stop and recover from addiction. (ispa.pt)
  • Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a limited view of the highly complex brain. (deepai.org)
  • This work presents a novel multi-scale coordinated framework for learning multiple representations from multimodal neuroimaging data. (deepai.org)
  • find that neuroimaging neuroimaging abnormalities across substance use disorders map to a common brain network that is similar across imaging modalities and substance use categories. (nature.com)
  • Investigating the neurocognitive mechanisms of emotion regulation: a multimodal approach combining invasive and noninvasive methods of neuroimaging and brain stimulation. (hse.ru)
  • This thematic series aims to provide a collection of papers addressing the novel pathophysiology and developing neuroimaging-guided treatments for headache disorders. (biomedcentral.com)
  • The neuroimaging methods have provided means for exploring the functional anatomy of the headache related nuclei. (biomedcentral.com)
  • Moreover, studies that aimed to develop new intervention approaches also applied neuroimaging techniques to associate the changes of brain responses with the changes of headache symptoms, exploring a deeper understanding of the treatment mechanism thus facilitating treatment protocols. (biomedcentral.com)
  • Advanced neuroimaging techniques have extensively contributed to elucidate the complex mechanisms underpinning the pathophysiology of migraine, a neurovascular disorder characterized by episodes of headache as. (biomedcentral.com)
  • Established by the NIMH in 2000, the Molecular Imaging Branch (MIB) uses a variety of neuroimaging techniques to explore molecular and chemical mechanisms associated with neural function in health and disease. (nih.gov)
  • Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability medRxiv. (usc.edu)
  • He started working in the field of neuroimaging in 2013 with experience in brain imaging and analysis. (edu.au)
  • His research is focused on the integrative translational neuroimaging, including generating and testing hypotheses and identifying brain changes underlying neurological and mental disorders. (edu.au)
  • She will also serve as chief of the Neuropsychoimaging of Addiction and Related Conditions (NARC) research program, directing her lab in its continued use of multimodal functional neuroimaging to explore the neurobiological basis of impaired cognitive and emotional functioning in human drug addiction and other disorders of self-regulation. (bnl.gov)
  • David's research interests include auditory processing and advanced multimodal neuroimaging approaches to better understand brain activity. (harvard.edu)
  • Over the last decades, non-invasive in-vivo neuroimaging techniques such as magnetic resonance imaging (MRI) have been increasingly applied to measure structure and function in human brains. (unm.edu)
  • This work has elucidated structural and functional neuroimaging findings are related to depression and treatment outcomes. (vumc.org)
  • Multimodal neuroimaging using PET and fMRI to investigate effects of 5-HT2AR modulation using the classic psychedelic psilocybin and the antogonist ketanserin. (regionh.dk)
  • MRI can be considered the preferred neuroimaging examination for Alzheimer disease because it allows accurate measurement of the 3-dimensional (3D) volume of brain structures, especially the size of the hippocampus and related regions. (medscape.com)
  • Neuroimaging is widely believed to be generally useful for excluding reversible causes of dementia syndrome such as normal-pressure hydrocephalus, brain tumor, and subdural hematoma, and for excluding other likely causes of dementia such as cerebrovascular disease. (medscape.com)
  • Arterial spin labeling MRI at baseline will be used to test whether brain perfusion can predict outcomes. (biomedcentral.com)
  • För att studera hjärnans struktur använder jag mig av T1, diffusion tensor imaging (DTI) och perfusion imaging. (su.se)
  • Visual assessment of brain perfusion MRI scans in dementia: a pilot study. (lu.se)
  • EEG analyses (event-related potential, slow brain potential, as well as lateralization, time and frequency spectral analyses, including EEG-EEG and EEG-EMG coherence and power measurements) are employed for the imaging of cortical correlates. (unimedizin-mainz.de)
  • In this study, we aim to assess the cortical functional network topological characteristics of NDPH using n. (biomedcentral.com)
  • In another series of studies in her lab, Goldstein has shown that oral methylphenidate-a mild stimulant used to treat attention deficit hyperactivity disorder (ADHD)-can reduce impulsivity and normalize prefrontal cortical function in cocaine-addicted individuals. (bnl.gov)
  • The thalamus is involved in regulating several brain functions, including motor, sensory, and higher cortical functions, and acts as a gateway between cortical and subcortical areas 13 , 14 . (phoenixrising.me)
  • Shaping brain structure: Genetic and phylogenetic axes of macroscale organization of cortical thickness. (mpg.de)
  • In summary, via the two frameworks, our work has made several contributions to advance FC analysis, which improves our understanding of underlying brain function and structure, and our findings may be ultimately useful for the development of biomarkers of mental disease. (unm.edu)
  • Multimodal MRI studies of fatigue in NMOSD are needed to find more precise imaging biomarkers for fatigue. (phoenixrising.me)
  • Structural imaging, preferably with MRI when possible and with computed tomography (CT) when not, should be performed as a first-tier approach. (medscape.com)
  • In this retrospective study, Wen and colleagues used data from the Adolescent Brain and Cognitive Development cohort study to investigate the neurobiological, psychological and social characteristics that are associated with self-injurious thoughts and behaviours transitions in children. (nature.com)
  • In this project, we investigate the neurobiological mechanisms of the multimodal processing of Fake News and the neural mechanisms underling various persuasive manipulations of the processing of Real News. (hse.ru)
  • Correlation and mediation analyses were conducted to investigate the associations among baseline REM%, multimodal brain imaging measures, and the improvement of depressive symptoms at follow-up in MDD. (bvsalud.org)
  • We recorded concurrent fNIRS with magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) in order to investigate the group-level correspondence of these measures with source-localized fNIRS estimates. (humanconnectome.org)
  • Transcranial magnetic stimulation (TMS) represents a methodology in which nerve and muscle cells can be contactlessly and painlessly stimulated via the induction principle. (unimedizin-mainz.de)
  • The authors conducted a systematic review and meta-analysis to identify predictors of placebo response in repetitive transcranial magnetic stimulation treatment for depression. (nature.com)
  • While electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are both effective in treating depressive episodes, their mechanisms of action are, however, not completely understood. (biomedcentral.com)
  • Transcranial direct current stimulation (tDCS) is a non-invasive technique recently employed in disorders of consciousness, and determining a transitory recovery of signs of consciousness in almost half of minimally conscious state (MCS) patients. (frontiersin.org)
  • We conduct a comprehensive evaluation of the taxonomy using functional and structural magnetic resonance imaging (MRI) data across a spectrum of Alzheimer's disease phenotypes and show that self-supervised models reveal disorder-relevant brain regions and multimodal links without access to the labels during pre-training. (deepai.org)
  • Brain structure and allelic associations in Alzheimer's disease CNS Neurosci Ther. (usc.edu)
  • Overall, we plan to test the hypothesis that modern multimodal methods that allow quantification of patterns of interaction between brain regions will be able to uncover key mechanisms of self-control of social cognition. (hse.ru)
  • Working with high-field magnetic resonance spectrometers, this Section develops novel NMR methods and applies them to the study of neurotransmission and neurometabolism, with significant opportunities available for multi-modal collaborative imaging using MRS, MRI, and PET. (nih.gov)
  • With the advent of high-throughput image processing and quantification methods, new radiographic attributes of AVM-related epilepsy have been identified. (medscape.com)
  • Existing methods based on brain morphometry and single-layer brain network cannot characterize the subtle structural differences related to self-esteem. (researchsquare.com)
  • Most existing methods use ROI-based brain network analysis methods to study brain structure and functional connections related to self-esteem. (researchsquare.com)
  • In addition to this new data-collection, we are working with several large-scale open developmental datasets that include EEG, functional and structural MRI, and diffusion MRI. (fluxsociety.org)
  • The axial diffusion-weighted image (middle) demonstrates high signal in the same area with corresponding low signal on the apparent diffusion coefficient (ADC) maps, consistent with true restricted diffusion and an acute infarction. (medscape.com)
  • Outside the field of epilepsy, EEG-fMRI has been used to study event-related (triggered by external stimuli) brain responses and provided important new insights into baseline brain activity during resting wakefulness and sleep. (wikipedia.org)
  • David is excited to learn how the Gow lab approaches advanced and complex analyses of brain data to contribute to the understanding of how the brain responds to complex auditory stimuli. (harvard.edu)
  • This article suggests that DIED consists in the disruption of subpersonal processes underlying the "minimal" or "embodied" self, i.e., the basic experience of being a self rooted in multimodal integration of self-related stimuli. (frontiersin.org)
  • Brain function is typically measured using task-based functional MRI (tfMRI) in which subjects perform tasks or experience sensory stimuli, and uses imaging sensitive to local changes in blood oxygenation and flow caused by brain activity in grey matter. (biorxiv.org)
  • We aim to systematically summarise the findings from fMRI studies which examined brain function in cannabis users while exposed to cannabis vs neutral stimuli during a cue-reactivity fMRI task. (edu.au)
  • The literature consistently reported greater brain activity in cannabis users while exposed to cannabis vs neutral stimuli in three key brain areas: the striatum, the prefrontal (anterior cingulate, middle frontal) and the parietal cortex (posterior cingulate/precuneus) and additional brain regions (hippocampus, amygdala, thalamus, occipital cortex). (edu.au)
  • Studies of the systemic mechanisms of deep brain stimulation treatment in patients with movement disorders (incl. (unimedizin-mainz.de)
  • They conducted multiple analyses and estimated underlying mechanisms related to brain structure, immunometabolism and genetics. (nature.com)
  • A number of studies have shown that social influence is associated with neural activity in the medial prefrontal cortex and ventral striatum, which are two brain areas involved in the fundamental and not exclusively social mechanisms of performance monitoring. (hse.ru)
  • By examining these variables in patients, at-risk offspring and healthy subjects, her research group intends to uncover common and specific mechanisms of these disorders, as well as multimodal and cross-diagnostic markers of vulnerability to ED in at-risk offspring. (unige.ch)
  • Evidence of traumatic brain injury: impact to the head or other mechanisms of rapid movement or displacement of the brain within the skull with any of the following: loss of consciousness, posttraumatic amnesia, disorientation and confusion, neurologic signs such as new onset of seizures, anosmia, or hemiparesis. (medscape.com)
  • Dr. Newhouse's research has focused on central nicotinic mechanisms in degenerative brain disorders and the role of nicotinic receptor systems in normal and disordered cognitive functioning in humans. (vumc.org)
  • The objectives of the Montreal Neurological Institute's Early Drug Discovery Unit (EDDU) are to train the next generation of researchers on stem cells, translate fundamental research and technology into industry-standard assays and to work towards identifying new treatments for neurological disorders. (mcgill.ca)
  • Embodied neurology: an integrative framework for neurological disorders. (lu.se)
  • We carried out genome-wide association studies of 3,144 distinct functional and structural brain imaging derived phenotypes in UK Biobank (discovery dataset 8,428 subjects). (biorxiv.org)
  • Selective disruption of sociocognitive structural brain networks in autism and alexithymia. (mpg.de)
  • Practice parameters for diagnosis and evaluation of dementia, as published by the American Academy of Neurology (AAN), consider structural brain imaging to be optimal. (medscape.com)
  • Here, we present a Heterogeneous Graph neural network for Multimodal neu. (deepai.org)
  • He says the research demonstrates that, independent of brain growth and development, a child's FNC is robust and stable with high similarity across scans and can serve as a fingerprint to identify an individual child from a large group. (futurity.org)
  • Moreover, the baseline REM% was correlated with the improvement of depressive symptoms from acute to remitted status in patients through regulating brain activity in the left inferior temporal gyrus and cerebral blood flow in the bilateral paracentral lobule. (bvsalud.org)
  • By assessing the temporal coherence of the hemodynamic activity among brain regions, FC is considered capable of characterizing the large-scale integrity of neural activity. (unm.edu)
  • Magnetic resonance imaging pattern learning in temporal lobe epilepsy: Classification and prognostics. (mpg.de)
  • Brain iron redistribution in mesial temporal lobe epilepsy: A susceptibility-weighted magnetic resonance imaging study. (mpg.de)
  • Axial, T2-weighted magnetic resonance imaging (MRI) scan reveals atrophic changes within bilateral temporal lobes with prominence of the sylvian fissures. (medscape.com)
  • Research in machine learning for autism spectrum disorder (ASD) classifi. (deepai.org)
  • Multidimensional neuroanatomical subtyping of autism spectrum disorder. (mpg.de)
  • RESULTS: We found voxel-wise correlations between baseline REM% and multimodal brain imaging metrics in many brain regions involved in sensorimotor, visual processing, emotion, and cognition in patients with MDD. (bvsalud.org)
  • Additionally, they were able to identify brain-behavior correlations with parent psychopathology and prenatal exposure to marijuana and other drugs. (futurity.org)
  • Wondering about the use for this purpose of a multimodality imaging approach, encompassing MRI, PET, EEG/ERPs and neuropsychological measures? (mssm.edu)
  • The Genetic Architecture of Multimodal Human Brain Age bioRxiv. (usc.edu)
  • MRI can provide intermediate or endo-phenotypes that can be used to assess the genetic architecture of such disorders. (biorxiv.org)
  • Graph analysis reveals the interaction among brain regions based on graph theory, while the multimodal fusion framework enables us to utilize the strength of different imaging modalities through joint analysis. (unm.edu)
  • Brain image reveals hippocampal atrophy, especially on the right side. (medscape.com)
  • The concomitant rich and flexible unsupervised deep learning framework captures complex multimodal relationships and provides predictive performance that meets or exceeds that of a more narrow supervised classification analysis. (deepai.org)
  • We present elaborate quantitative evidence of how this framework can significantly advance our search for missing links in complex brain disorders. (deepai.org)
  • And finally, we utilized a multimodal fusion analysis framework, multi-set canonical correlation analysis + joint independent component analysis (mCCA+jICA) to link functional and structural abnormalities in BD and MDD. (unm.edu)
  • The simultaneous acquisition of EEG and fMRI data of sufficient quality requires solutions to problems linked to potential health risks (due to currents induced by the MR image forming process in the circuits created by the subject and EEG recording system) and EEG and fMRI data quality. (wikipedia.org)
  • BACKGROUND: Machine learning (ML) can distinguish cases with psychotic disorder from healthy controls based on magnetic resonance imaging (MRI) data, but it is not yet clear which MRI metrics are the most informative for case control ML, or how ML algorithms relate to the underlying biology. (maastrichtuniversity.nl)
  • used real-world data from the UK healthcare system to perform an economic evaluation comparing the cost-effectiveness of in-person and internet-delivered cognitive behavioral therapy for mood and anxiety disorders. (nature.com)
  • In this work, we present two data analysis frameworks for biomarker detection on brain imaging with FC, 1) graph analysis of FC and 2) multimodal fusion analysis, to better understand the human brain. (unm.edu)
  • Individuals with BD showed functional differences in the right posterior cingulate cortex during resting-state experiments, the left amygdala during emotional experiments, including those using a mixed (positive/negative) valence manipulation, and the left superior and right inferior parietal lobules during cognitive experiments, while hyperactivating the left medial orbitofrontal cortex during cognitive experiments. (nature.com)
  • Currently we are working on several studies of patients with movement disorders (incl. (unimedizin-mainz.de)
  • We study human perception of the urban environment, the effects of the environment on the human brain (neuro-urban studies) and the influence of different elements of the environment on cognitive processes. (hse.ru)
  • After achieving medical studies, Camille Piguet-Nemitz completed a PhD in neurosciences on mood disorders. (unige.ch)
  • Because different imaging technologies have distinct capabilities, strengths, and limitations, studies are designed so that the same subjects are iteratively studied using multiple techniques to provide complementary information about pathophysiology. (nih.gov)
  • The NIMH PET radiochemistry facility is directed by Victor Pike, PhD. This laboratory is fully equipped for radiochemistry research and development as well as production of PET radiopharmaceuticals for imaging studies. (nih.gov)
  • With functional MRI (fMRI) or structural MRI (sMRI), studies have identified neurophysiological deficits in patients' brain from different perspective. (unm.edu)
  • These results provide an important validation of source-localized fNIRS in the context of concurrent multimodal imaging for future studies of the relationship between physiological effects in the human brain. (humanconnectome.org)
  • Brain imaging studies suggest that self-esteem involves multiple psychological processes, including self in perception, memory, and introspection. (researchsquare.com)
  • Limitations of the study include the fact that a large proportion of patients underwent withdrawal of life-sustaining therapy and, thus, the performance of the multimodal approach of EEG and fMRI may be subject to bias. (reliasmedia.com)
  • Neurovascular dysfunction, including blood-brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, is increasingly recognized as contributing to Alzheimer disease. (medscape.com)
  • Camille Piguet-Nemitz's lab seeks to help young people better manage their stress, which can lead to anxiety disorders and depression. (unige.ch)
  • Depression is a debilitating disorder, and at least one third of patients do not respond to therapy. (researchgate.net)
  • This basic research is highly significant because it has powerful translational implications for treating addictive disorders and allowing doctors to individually tailor intervention approaches to minimize relapse. (bnl.gov)
  • The neurocognitive disorder presents immediately after the occurrence of the TBI or immediately after recovery of consciousness and persists past the acute post-injury period. (medscape.com)
  • Impaired brain metabolism and neurocognitive function in childhood leukemia survivors despite complete hormone supplementation in adulthood. (lu.se)
  • See Pediatric Concussion and Other Traumatic Brain Injuries , a Critical Images slideshow, to help identify the signs and symptoms of TBI, determine the type and severity of injury, and initiate appropriate treatment. (medscape.com)
  • More broadly, his research attempts to leverage knowledge from multiple disciplines and lines of work to generate findings that can inform better evidence-based interventions for promoting the prevention and treatment of substance use disorders. (ispa.pt)
  • UPTON, NY - Brookhaven Lab's Rita Z. Goldstein has won the Joel Elkes Research Award for her work on how drugs affect the brain and behavior. (bnl.gov)
  • Goldstein expressed her gratitude to members of the current Brookhaven Neuropyschoimaging group, which she co-directs with Nelly Alia-Klein - including post-docs Scott Moeller and Muhammad Parvaz, graduate student Anna Konova, senior staff members Thomas Maloney and Patricia Woicik, and numerous undergraduate and high school students, as well as research volunteers and support staff - and Brookhaven's entire medical imaging group, including Joanna Fowler, David Schlyer, and Gene-Jack Wang. (bnl.gov)
  • Recently, the use of large datasets and graph theory has been identified among key future directions in brain symmetry research. (cas.cz)
  • David Gow is a researcher in the Department of Neurology at the Massachusetts General Hospital with research and teaching appointments at the Harvard Medical School (Instructor), Salem State University (Professor of Psychology), the Athinoula A. Martinos Center for Biomedical Imaging, and the Harvard University Speech and Hearing Bioscience and Technology Program. (harvard.edu)
  • Dr. Ahlfors' research concerns spatiotemporal imaging of human brain function. (harvard.edu)
  • At the Neuropsychoimaging of Addiction and Related Conditions (NARC) Research Program, we study the neurobiology of substance use disorders and common comorbid problem behaviors and psychopathologies such as aggression and intermittent explosive disorder. (mssm.edu)
  • In this talk, I will discuss research showing how cognition can be leveraged in various contexts - from functional magnetic resonance imaging (fMRI) to ecological momentary assessment (EMA) - to better understand brain-behaviour associations in severe mental illness. (mcgill.ca)
  • 2010). Total resection or functional disconnection of the epileptogenic zone (EZ) which is area of cortex responsible for the generation of epileptic seizures, for achieving seizure-freedom while preserving vital cortex areas responsible for sensory processing and avoiding post-operative neurological deficits is the ideal outcome of surgery (Rosenow and Luders, 2001, Tellez-Zenteno, 2005). (veterinaryevidence.org)
  • Up to now, EEG-fMRI has been mainly seen as an fMRI technique in which the synchronously acquired EEG is used to characterise brain activity ('brain state') across time allowing to map (through statistical parametric mapping, for example) the associated haemodynamic changes. (wikipedia.org)
  • Human Brain Mapping. (kcl.ac.uk)
  • Structural MRI measures of brain anatomy include tissue and structure volumes, such as total grey matter volume and hippocampal volume, while other MRI modalities allow the mapping of different biological markers such as venous vasculature, microbleeds and aspects of white matter (WM) micro-structure. (biorxiv.org)
  • An axial T2 FLAIR image (left) demonstrates high signal in the lentiform nucleus with mass effect. (medscape.com)
  • The proposed method provides a new perspective for the analysis of brain structure differences of self-esteem, which also has potential guiding significance in other researches involved brain cognitive activity and brain disease diagnosis. (researchsquare.com)
  • Disclaimer: The ACR Committee on Appropriateness Criteria and its expert panels have developed criteria for determining appropriate imaging examinations for diagnosis and treatment of specified medical condition(s). (bvsalud.org)
  • Parkinson's), as well as being involved in projects concerning the optimization of the efficacy of deep brain stimulation. (unimedizin-mainz.de)
  • With TMS, brain stimulation is achieved through rapidly changing magnetic fields that induce electric currents underneath a ferromagnetic coil. (biomedcentral.com)
  • however, the effects of brain stimulation, particularly those of non-invasive stimulation, are variable. (imperial.ac.uk)
  • Computational models constitute a useful tool to explore the vast sea of stimulation parameters and characterise their effects on brain activity. (imperial.ac.uk)
  • This piece is centred on the application of phenomenological and biophysical models in non-invasive brain stimulation. (imperial.ac.uk)
  • We first introduce common forms of brain stimulation and computational models, and provide typical construction choices made when building phenomenological and biophysical models. (imperial.ac.uk)
  • We conclude by proposing future directions to fully realise the potential of computational models of brain stimulation for the design of personalized, efficient, and effective stimulation strategies. (imperial.ac.uk)
  • Susceptibility-based imaging aids accurate distinction of pediatric-onset MS from myelin oligodendrocyte glycoprotein antibody-associated disease. (ucsf.edu)
  • Alzheimer disease is a progressive neurodegenerative disorder characterized by gradual onset of dementia . (medscape.com)
  • and the Molecular Imaging and Optogenetics group (Institute for microscopic Anatomy und Neurobiology, Prof A. Stroh) . (unimedizin-mainz.de)
  • But they believe that intra-subject variation of FNC can carry biologically meaningful information, especially during adolescence, which is a time of significant change in the brain. (futurity.org)