Diseases skull neoplasms. Medical search. Frequent questions

Benign tumors of the skull base include true neoplasms, inflammatory masses, cysts, and developmental anomalies occurring at the osseous interface between the brain and the underlying structures of the head and neck. (medscape.com)
Because of the complexities of the anatomic region and the relatively low incidence, patients with skull base tumors are best managed by an experienced multidisciplinary team. (medscape.com)
The treatment of choice for the vast majority of benign skull base tumors is surgical excision. (medscape.com)
As a whole, tumors of the skull base are uncommon entities, and the majority of them are malignant. (medscape.com)
Benign skull base tumors can be classified into the pathogenetic and histologic groups listed below. (medscape.com)
While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
Skull tumors may affect the brain by local extension. (vin.com)
Pituitary gland neoplasms and tumors arising from cranial nerves are considered secondary brain tumors. (vin.com)
Because of local invasion, many tumors (especially skull-base chordomas) may not be amenable to complete surgical excision, and the local recurrence rate is high. (medscape.com)
Tumors detected and diagnosed early have a favorable prognosis if treated with a complete or en-bloc excision. (medscape.com)
Neoplasms originating from the blood or bone marrow (leukemias and myeloproliferative disorders) are not considered solid tumors. (mycancergenome.org)
Tumors of the cranial nerve sheath constitute 5% to 10% of all intracranial neoplasms, yet few articles have described their CT and MR characteristics. (ajnr.org)
We report the imaging findings in a relatively large series of schwannomas of the jugular foramen, contrasting them with other disease entities, especially vestibular schwannomas and tumors of the glomus jugulare. (ajnr.org)
Cranial nerve sheath tumors constitute 5% to 10% of all intracranial neoplasms. (ajnr.org)
A fully endoscopic approach is used for a variety of skull base lesions including pituitary tumors, encephaloceles, cerebrospinal fluid leaks, craniopharyngiomas, Chordomas and meningiomas. (endoscopicskullbasesurgery.com)
Fractures, bone tumors, neurologic disease, and abnormalities in calcium and phosphate balance can also occur. (medilib.ir)
When possible, en bloc surgical resection has been the recommended treatment for these tumors. (fortuneonline.org)
Diseases affecting or involving the PARANASAL SINUSES and generally manifesting as inflammation, abscesses, cysts, or tumors. (rush.edu)
The laboratory focuses on developing new therapies for brain and skull base tumors , and has established the first primary skull base chordoma xenograft mouse model. (hopkinsmedicine.org)

On one end, the clinical spectrum includes an acute, fulminant, disseminated disease called Letterer-Siwe disease, and, on the other end, solitary or few, indolent and chronic lesions of bone or other organs called eosinophilic granulomas . (medscape.com)
The intermediate clinical form called Hand-Schüller-Christian disease is characterized by multifocal, chronic involvement and classically presents as the triad of diabetes insipidus, proptosis, and lytic bone lesions. (medscape.com)
The lesions responsible for the disruption of ADH synthesis or secretion in hypophyseal diabetes insipidus include large pituitary neoplasms (endocrinologically active or inactive), a dorsally expanding cyst or inflammatory granuloma, and traumatic injury to the skull, with hemorrhage and glial proliferation in the neurohypophyseal system. (merckvetmanual.com)

Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
Cerebral meningioma is the most frequently reported primary brain tumor of cats and accounts for almost 10% of all nonhematopoietic neoplasms. (vin.com)
in five patients, tumor extended below the skull base. (ajnr.org)
We report a complication of single dose intent to treat SBRT for a sacral chordoma that should serve to remind oncologists that radiation therapy, like surgery, is not without serious potential complications and that surgical resection may still be the best option for patients whose tumor can be treated with en bloc resection. (fortuneonline.org)
Current literature clearly demonstrates that wide en bloc resection with negative surgical margins is the single most important predictor of tumor recurrence and long term survival [1, 2]. (fortuneonline.org)
The targets for CT-based RT planning included the gross tumor volume (GTV) (primary tumor and lymph node metastases) and the clinical target volume (CTV) (postoperative tumor bed, expansions of the GTVs and lymph node groups at risk of subclinical disease). (nih.gov)
Lymph node targets at risk of subclinical disease included the bilateral jugulodigastric and lower jugular lymph nodes, bilateral retropharyngeal lymph nodes at risk, and high jugular nodes at the base of skull in the side of the neck at highest risk (containing clinical neck metastases and/or ipsilateral to the primary tumor). (nih.gov)
The median RT doses to the gross tumor, the operative bed, and the subclinical disease PTVs were 70.4 Gy, 61.2 Gy, and 50.4 Gy respectively. (nih.gov)
Ten patients (80%) relapsed in-field (in areas of previous gross tumor in nine patients), and two patients developed marginal recurrences in the side of the neck at highest risk (one in the high retropharyngeal nodes/base of skull and one in the submandibular nodes). (nih.gov)
Chordoma research is led by a comprehensive team including Gary Gallia, M.D., director of the N ... eurosurgery Skull Base Tumor Center. (hopkinsmedicine.org)

Operative procedures of the skull base are relatively recent developments within the field of head and neck surgery. (medscape.com)
Dr. Witterick's and Dr. Vescan's practices include advanced rhinology, endoscopic and open anterior skull base surgery and head and neck oncologic surgery. (utoronto.ca)
Approximately 200-250 endoscopic sinus surgery procedures/year plus significant exposure to head and neck oncology cases including endoscopic and open skull base resections for benign and malignant disease. (utoronto.ca)
The Department of Adult and Pediatric Oral, Maxillofacial Surgery offers the full range of surgical treatment for diseases, traumatic injuries, functional disorders and deformities of the jaw, oral cavity, teeth and face. (bookinghealth.com)
The fellowship is a 1 year comprehensive experience in Rhinology, advanced Endoscopic Sinus Surgery and Endoscopic Skull Base Surgery. (endoscopicskullbasesurgery.com)
The surgical experience encompasses primary and revision endoscopic sinus surgery, surgical management of the frontal sinus, cerebrospinal fluid leak closure, endoscopic resection of sino-nasal neoplasms and endoscopic skull base surgery. (endoscopicskullbasesurgery.com)
The combined Advanced Endoscopic Skull base surgery cases will be jointly performed with Dr.Theodore Schwartz who is on the Neurological Surgery faculty. (endoscopicskullbasesurgery.com)
It can arise as a result of an infection of the external auditory canal "malignant otitis externa," the middle ear, and sinusitis and as a complication of surgery of the skull base [1-3]. (docksci.com)
In this type, the disease begins in the epithelial lining cells of the proximal tubules and if localized, can be cured in well over 50% of patients with surgery alone. (thegonzalezprotocol.com)
A comprehensive and completely up-to-date anatomical guide to sinus and skull base surgery. (ebooksmedicine.net)
Seventy videos on operations detail the potential anatomical variations seen in the frontal sinuses, ancillary procedures such as DCR, orbital decompression, tightness of cerebrospinal fluid fistula and surgical approaches to the skull base.This classic reference is an indispensable resource for otolaryngologists, head and neck surgeons, as well as residents and trainees seeking a tutorial on the latest techniques in functional endoscopic sinus surgery (FESS). (ebooksmedicine.net)
It allows understanding of the three-dimensional anatomy affected by diseases, making decisions about the associated surgical treatment, and a functional endoscopic sinus surgery (FESS). (ebooksmedicine.net)

Experience in endoscopic resection of skull base benign and malignant neoplasms is gained (e.g., esthesioneuroblastoma, meningioma, chordoma). (utoronto.ca)

Increased bone pain with an enlarging soft tissue mass and a lytic lesion is suggestive of a neoplasm (osteosarcoma), especially if a pathogenic fracture is present. (medscape.com)
Representative examples include epithelial neoplasms (e.g. lung carcinoma, prostate carcinoma, breast carcinoma, colon carcinoma), and neoplasms arising from the soft tissues and bones (e.g. leiomyosarcoma, liposarcoma, chondrosarcoma, osteosarcoma). (mycancergenome.org)

Intracranial neoplasms can arise from any of the structures or cell types present in the cranial vault, including the brain, meninges, pituitary gland, skull, and even residual embryonic tissue. (cancernetwork.com)
Neurofibromatosis 1 is an autosomally dominated inherited genetic condition that predisposes those involved to the development of intracranial neoplasms. (medlink.com)

A neoplasm that arises from the anterior or posterior lobe of pituitary gland and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. (nih.gov)

In this report we present a case of a gentleman with a sacral chordoma who was offered en bloc resection but elected to proceed with SBRT. (fortuneonline.org)
Refinement of other surgical techniques includes medial endoscopic maxillectomy and resection of nasosinusal neoplasms. (ebooksmedicine.net)

Available at https://rarediseases.org/rare-diseases/chordoma/ . (medscape.com)
Chordoma and chondroid neoplasms of the spheno-occiput. (medscape.com)

Clinical manifestations of the disease are due to the defeat of the function of the musculoskeletal system and the development of specific nephropathy. (treat-simply.com)

The foundation of the fellowship experience includes the medical and surgical management of both routine and complex sino-nasal disorders including chronic sinusitis, allergic fungal sinusitis, advanced nasal polyposis, frontal sinus disease, sphenoid sinus disease and anterior skull base neoplasms. (endoscopicskullbasesurgery.com)

Thereafter, DQ did well until November 1991, when he noticed a lump in the left parietal-occipital region of the skull that rapidly enlarged over a period of several days. (thegonzalezprotocol.com)
On exam, I immediately noticed a lemon sized mass sticking out of his skull in the left parietal area. (thegonzalezprotocol.com)

Skull deformities may lead to hydrocephalus, basilar invagination, and cerebellar or brainstem compressive syndromes. (medscape.com)

Neoplasms involving the brain stem may result in cranial nerve deficits. (vin.com)

Often, the injury is minor because your skull is hard and it protects your brain. (icdlist.com)
But other head injuries can be more severe, such as a skull fracture, concussion, or traumatic brain injury. (icdlist.com)
With an open, or penetrating, injury, an object pierces the skull and enters the brain. (icdlist.com)
Radiology of Skull and Brain. (thejcdp.com)

The two main clinical manifestations of Paget disease are pain due to the pagetic lesion in bone itself or from secondary consequences of bone overgrowth and deformities in affected areas, such as osteoarthritis or nerve impingement. (medilib.ir)
It serves to demonstrate the multifocality of the disease, especially when only a mono-ostotic lesion is clinically suspected. (tau.ac.il)
A bone biopsy from a rib lesion disclosed fibrous dysplasia, and an extensive search for malignancy ruled out metastatic disease. (tau.ac.il)

common and rare nasal and sinus diseases. (utoronto.ca)
Upon completion of the program, the fellow will be trained to develop academic, tertiary sinus and endoscopic skull base program. (endoscopicskullbasesurgery.com)
The latest advances in use of Biologics in nasal polypoid sinus disease will be available for the fellow to gain knowledge. (endoscopicskullbasesurgery.com)
Paranasal Sinus Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
This graph shows the total number of publications written about "Paranasal Sinus Diseases" by people in this website by year, and whether "Paranasal Sinus Diseases" was a major or minor topic of these publications. (rush.edu)
Below are the most recent publications written about "Paranasal Sinus Diseases" by people in Profiles. (rush.edu)
Paranasal sinus mucoceles with skull-base and/or orbital erosion: is the endoscopic approach sufficient? (rush.edu)

As malignant cells have a tendency to round up in body fluids these non-epithelial neoplasms can therefore mimic reactive mesothelial cells and metastatic adenocarcinoma. (cytojournal.com)
4 Malignant effusions caused by non-epithelial neoplasms are more frequently encountered in children than in adults. (cytojournal.com)

Diagnosis of diabetes insipidus is based on chronic polyuria that does not respond to dehydration and is not due to primary renal disease. (merckvetmanual.com)

A knowledge graph of biological entities such as genes, gene functions, diseases, phenotypes and chemicals. (edu.sa)

endocrine, salivary and mucosal neoplastic diseases of the head and neck. (utoronto.ca)
If something is "neoplastic," it has to do with the neoplasm. (msdmanuals.com)

The skull base can be divided arbitrarily into anatomic subsites corresponding to the major intracranial compartments as follows: (1) anterior skull base (anterior cranial fossa), (2) middle skull base (middle cranial fossa), (3) posterior skull base (posterior cranial fossa), and (4) central skull base (brainstem). (medscape.com)

Head and neck oncologic surgeries are performed at Sinai Health and endoscopic and open skull base resections are performed at the University Health Network (Toronto Western Site) in conjunction with Neurosurgery. (utoronto.ca)
3. To gain experience in endoscopic and open skull base resections. (utoronto.ca)
An additional 1-2 endoscopic skull base cases per week are performed in conjunction with the neurosurgical team led by Dr. Theodore Schwartz. (endoscopicskullbasesurgery.com)
The endoscopic skull base program represents a rich educational experience for the developing Rhinologist. (endoscopicskullbasesurgery.com)
Sublabial transseptal vs transnasal combined endoscopic microsurgery in patients with Cushing disease and MRI-depicted microadenomas. (scielo.br)
Clinical utility of intraoperative volume computed tomography scanner for endoscopic sinonasal and skull base procedures. (rush.edu)

The key areas of the department's clinical practice include the treatment of benign and malignant maxillofacial neoplasms, dysgnathia, diseases and injuries of the temporomandibular joint, correction of the maxillofacial malformations, as well as correction of the cleft lip and palate in children. (bookinghealth.com)

This explains why the assessment of eventual disease recurrence, persistence, or progression should not be performed shortly after the completion of chemotherapy cycles. (hindawi.com)

PharmaEssentia develops treatments for myeloproliferative neoplasms, hepatitis and other diseases. (duval-ford.com)

PDB is an ancient disease, claimed to be identified in a Neanderthal skull, with scattered reports of skeletal remains throughout history demonstrating this disorganized pattern of bone overgrowth [ 12 ]. (medilib.ir)
The extent of skeletal involvement is diminishing, and cases of symptomatic disease are less frequent [ 15,19-25 ]. (medilib.ir)
Several issues are likely to have led to an underestimation of the prevalence of Paget disease, including the facts that it is often asymptomatic, that screening abdominal radiographs are no longer routine with hospital admission, and that the diminished skeletal extent of Paget disease has made it less likely to be incidentally detected. (medilib.ir)

Various surgical approaches have evolved to access the various parts of the skull base. (medscape.com)
The therapeutic options vary from the treatment of traumatic injuries of the jaws and facial skull with the reconstruction of soft tissues to surgical interventions in diseases of the oral cavity, face and surrounding structures. (bookinghealth.com)
The range is complemented by advanced methods of dental implantation and jaw bone reconstruction in elderly patients, as well as surgical treatment of temporomandibular joint diseases. (bookinghealth.com)

Internal anatomy of the skull base, lateral view, and base of the skull. (medscape.com)
MRI has evolved into the single most useful imaging study of the skull base and provides highly accurate representation of soft tissue structures. (medscape.com)
Accordingly, no accurate data regarding the incidence of benign skull base neoplasms are available. (medscape.com)
Softened bone at the base of the skull may lead to platybasia, the descent of the cranium onto the cervical spine. (medscape.com)
A systematic review by Bin-Alamer et al assessed SRS with or without postoperative fractionated radiation therapy in adults with skull-base chordomas. (medscape.com)
1. Introduction Malignant otitis externa (MOE) is a rare and potentially fatal invasive infection of the skull base. (docksci.com)
Skull Base Surg. (scielo.br)
Four regional recurrences extended superior to the jugulodigastric node, in the high jugular and retropharyngeal nodes near the base of skull of the side of the neck at highest risk. (nih.gov)

Back and neck pain are common complaints, as Paget disease frequently affects the spine, especially the lumbar and sacral regions. (medscape.com)

As Harrison's reports bluntly, "Investigational therapy is first-line treatment for metastatic disease as no immune approach or chemotherapeutic agent has shown significant antitumor activity. (thegonzalezprotocol.com)
When metastatic to distant organs, oncologists treat the disease as they would bladder cancer though with little success. (thegonzalezprotocol.com)
Few patients with metastatic disease survive six months. (thegonzalezprotocol.com)
A bone scan revealed "a large focal area of increased radiopharmaceutical uptake with a photopenic center consistent with metastatic disease in the left occipital region of the skull. (thegonzalezprotocol.com)
A repeat bone scan in June 1993, after DQ had completed some 16 months of treatment, revealed "No evidence of bony metastatic disease. (thegonzalezprotocol.com)
The authors present the case of a patient who was suspected of suffering from metastatic bone disease after bone scintigraphy demonstrating multiple, discrete, focal increased areas of activity. (tau.ac.il)
The authors suggest that polyostotic fibrous dysplasia can imitate metastatic bone disease and that this pattern, although uncommon, should be recognized. (tau.ac.il)

They represent the majority of paranasal neoplasms. (lookformedical.com)

In this disease, abnormal plasma cells of the bone marrow proliferate, which causes destruction of bone tissue. (treat-simply.com)
Paraneoplastic Syndromes A neoplasm is an abnormal growth in your body that may be cancerous. (msdmanuals.com)

Other patients with Paget disease present with a range of manifestations related to complications. (medscape.com)

Inflammatory and other diseases of the CNS (e.g. (cdc.gov)

We have shown that each colon neoplasm arises from a clonal expansion of one transformed cell. (hopkinsmedicine.org)

In these patients, the incidental finding of an elevated serum alkaline phosphatase level or characteristic radiographic abnormality may lead to detection of the disease. (medscape.com)
The most common cranial symptom is hearing loss, occurring in 30-50% of patients with skull involvement. (medscape.com)
Vertigo or tinnitus may occur with a frequency of 25% in patients who have Paget disease with cranial involvement. (medscape.com)
The physical examination findings may be normal in patients with Paget disease. (medscape.com)
ABL1 is altered in 1.76% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
BCR is altered in 1.37% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
BRAF is altered in 6.45% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
NF1 is altered in 7.01% of solid neoplasm patients [ 2 ]. (mycancergenome.org)
In one series, only 7 of 24 patients recognized as having Paget disease had been diagnosed during their lifetimes (29 percent) [ 17 ]. (medilib.ir)
Thus, abdominal radiographs tend to capture the proximal femurs, pelvis, and lumbar spine (common sites of Paget disease) but miss patients with monostotic disease of the skull, upper spine, or distal extremity. (medilib.ir)
However, a study of a population-based cohort from the Netherlands suggested that although sAP is a marker for PDB, the sAP level is normal in the majority of patients with Paget disease, particularly those with monostotic disease [ 26 ]. (medilib.ir)
FDG-PET or PET/CT seems to be helpful in assessing the response to treatment in patients with MM and in the evaluation of possible sites of recurrent or progressive disease. (hindawi.com)
Due to the potential increased susceptibility of patients with neurofibromatosis 1 to the deleterious side effects of radiation therapy, such as mutagenesis and vasculopathy, alternative treatments are required for patients with progressive disease. (medlink.com)

Cancer isn't one disease, but many. (msdmanuals.com)

Anatomy5

Organisms1

Diseases14

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Tumors20

Lesions3

Tumor10

Surgery12

Meningioma1

Osteosarcoma2

Intracranial neoplasms2

Pituitary gland1

Resection2

Chordoma2

Musculoskeletal1

Disorders1

Parietal2

Hydrocephalus1

Cranial nerve1

Brain4

Lesion3

Sinus7

Epithelial2

Primary1

Genes1

Neoplastic2

Anterior1

Endoscopic6

Malformations1

Recurrence1

Myeloproliferative1

Skeletal3

Surgical3

Base8

Neck1

Metastatic7

Paranasal1

Abnormal2

Manifestations1

Inflammatory1

Arises1

Patients13

Cancer1