2023CentersWorld Health OrganInflammatory Bowel DParkinson's2019Genetic diseasesAlzheimer's DiseaseDiagnosisSymptomsNeurodegenerativeInfectious diseaseEmerging InfectioGeneticsAffectsControl of neglected tropicalDisordersSevereSickle Cell DiNoncommunicable2017Mitochondrial diseasesTherapiesWorld'sChronic diseasesAutoimmune diseasesPatientsGenesOutbreaksZoonoticCarried Chagas diseaseIllnessesProgressesCeliac diseaseParasiticInfectionsHumansRenalSexually TransmitInterstitial lung diEpidemicsTropical diseasesContentComplicationsDengueKidneyNCDsAddison's DiseaseTreatments for rare diseasesPathogens7,000InflammationLymeCommonCoronary heart dHUNTINGTON DISEASEFellowship ProgramInfectionPeople
20232
- Fast Five Quiz: Alzheimer's Disease Comorbidities - Medscape - Mar 30, 2023. (medscape.com)
- Fast Five Quiz: Inherited Retinal Diseases - Medscape - Mar 31, 2023. (medscape.com)
Centers8
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- The use or display of syndicated content from the Centers for Disease Control and Prevention (CDC) does not does not imply endorsement or government sanction of any third party causes, ideas, web sites, products or services by the CDC. (cdc.gov)
- Syndication of content provided by the Centers for Disease Control and Prevention (CDC) does not imply endorsement or government sanction of any company or its products by the CDC. (cdc.gov)
- courtesy of the US Centers for Disease Control and Prevention). (medscape.com)
- Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
- The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. (cdc.gov)
- The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
- The Centers for Disease Control and Prevention estimates that in 2013, antibiotic resistance threats caused more that 2 million illnesses and 23,000 deaths in the United States and that in 2011, those threats were responsible for an estimated $20 million in excess health care costs, 8 million additional hospital days, and $35 million in societal costs. (cdc.gov)
World Health Organ3
- Disease data source: World Health Organization. (cdc.gov)
- The World Health Organization (WHO) and Sanofi - one of the world's leading pharmaceutical companies - have signed a new agreement for donations of medicines to sustain specific efforts to eliminate neglected tropical diseases (NTDs). (news-medical.net)
- The World Health Organization (WHO) recently released the latest draft of its International Compendium of Diseases. (thenextweb.com)
Inflammatory Bowel D3
- Inflammatory bowel disease (IBD) describes conditions that cause inflammation in the lining of the intestinal wall. (healthline.com)
- In addition HUB generated models for other diseases such as Inflammatory Bowel Disease (IBD), Chronic Obstructive Pulmonary Disease (COPD) and genetic diseases such as cystic fibrosis (CF). The company has also introduced adult stem cell-derived kidney organoids, and continues to investigate the molecular mechanisms of tissue development and cancer using organoids generated from adult Lgr5 stem cells. (corning.com)
- Most of the comorbidities associated with AD, including diabetes, cardiovascular disease, depression, and inflammatory bowel disease (IBD), are closely related to inflammation. (medscape.com)
Parkinson's27
- Parkinson's disease is a progressive disorder that affects the nervous system and the parts of the body controlled by the nerves. (mayoclinic.org)
- In the early stages of Parkinson's disease, your face may show little or no expression. (mayoclinic.org)
- Parkinson's disease symptoms worsen as your condition progresses over time. (mayoclinic.org)
- Although Parkinson's disease can't be cured, medications might significantly improve your symptoms. (mayoclinic.org)
- Parkinson's disease signs and symptoms can be different for everyone. (mayoclinic.org)
- Over time, Parkinson's disease may slow your movement, making simple tasks difficult and time-consuming. (mayoclinic.org)
- Or you may fall or have balance problems as a result of Parkinson's disease. (mayoclinic.org)
- See your health care provider if you have any of the symptoms associated with Parkinson's disease - not only to diagnose your condition but also to rule out other causes for your symptoms. (mayoclinic.org)
- In Parkinson's disease, certain nerve cells (neurons) in the brain gradually break down or die. (mayoclinic.org)
- When dopamine levels decrease, it causes atypical brain activity, leading to impaired movement and other symptoms of Parkinson's disease. (mayoclinic.org)
- Researchers have identified specific genetic changes that can cause Parkinson's disease. (mayoclinic.org)
- But these are uncommon except in rare cases with many family members affected by Parkinson's disease. (mayoclinic.org)
- However, certain gene variations appear to increase the risk of Parkinson's disease but with a relatively small risk of Parkinson's disease for each of these genetic markers. (mayoclinic.org)
- Her research focuses on medical genetics and stem cell modeling to unlock disease mechanisms and pathways leading to neurodegeneration in Parkinson's disease and related disorders, and to develop new therapeutic strategies to advance precision medicine. (stanford.edu)
- During her neurology internship from 2001 to 2002 at Medical University of Lübeck with Prof. Christine Klein, Dr. Schüle studied genes for inherited forms of Parkinson's disease and dystonia. (stanford.edu)
- He is a senior anatomic neuropathologist with considerable experience in the evaluation and assessment of Alzheimer's disease, Parkinson's disease and other neurodegenerative disorders. (stanford.edu)
- Types include Alzheimer's disease and Parkinson's disease . (medlineplus.gov)
- Resources on the diagnosis, management, and treatment of Parkinson's disease. (medicalnewstoday.com)
- Parkinson's disease is a neurological condition that affects movement and thinking. (medicalnewstoday.com)
- What is early onset Parkinson's disease? (medicalnewstoday.com)
- Early onset Parkinson's disease develops before the age of 50 years. (medicalnewstoday.com)
- What are the risk factors for Parkinson's disease? (medicalnewstoday.com)
- Is Parkinson's disease passed on through genetics? (medicalnewstoday.com)
- Parkinson's disease is a neurological condition. (medicalnewstoday.com)
- Ongentys (opicapone) is a prescription drug that's used to treat Parkinson's disease. (medicalnewstoday.com)
- Colorado will spend more than $8 million researching marijuana's medical potential, awarding grants for studies on treating epilepsy, brain tumors, Parkinson's disease and post-traumatic stress disorder. (journalrecord.com)
- Neurodegenerative diseases (NDs) are chronic conditions that result in progressive damage to the nervous system , including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and Amyotrophic lateral sclerosis (ALS). (bvsalud.org)
20194
- In July 2019, the US Food & Drug Administration (FDA) approved the use of concurrent or sequential EIA testing for diagnosis of Lyme disease. (medscape.com)
- In July 2019, in pursuit of that future, Junior enrolled in a clinical trial for an experimental stem cell gene therapy for sickle cell disease. (ucla.edu)
- It is estimated that 6.5 million people, mostly in Mexico , Central America and South America , have Chagas disease as of 2019, [1] [3] resulting in approximately 9,490 annual deaths. (wikipedia.org)
- The coronavirus disease 2019 (COVID-19) is a communicable respiratory disease caused by a new strain of coronavirus that causes illness in humans. (africacdc.org)
Genetic diseases2
- Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-function, and how natural ligands can restore protein function and homeostasis in genetic diseases. (elsevier.com)
- The mitochondrial myopathies are a group of genetic diseases that affect the mitochondria in the cells. (bellaonline.com)
Alzheimer's Disease21
- What is Alzheimer's Disease? (alz.org)
- Alzheimer's disease accounts for 60-80% of dementia cases. (alz.org)
- Alzheimer's disease is considered to be younger-onset Alzheimer's if it affects a person under 65. (alz.org)
- Alzheimer's disease progresses in stages, with the severity of symptoms increasing over time. (alz.org)
- If those changes are present, the person may progress into dementia due to Alzheimer's disease, which can be divided into three stages - mild, moderate and severe - representing a progressive loss of independence. (alz.org)
- A person living with mild dementia due to Alzheimer's disease will typically start to experience symptoms that interfere with some daily activities. (alz.org)
- Symptoms are more pronounced for someone living with moderate dementia due to Alzheimer's disease and will interfere with many of their daily activities. (alz.org)
- An individual living with severe dementia due to Alzheimer's disease will experience symptoms that interfere with most everyday activities. (alz.org)
- Alzheimer's has no cure , but one treatment - aducanumab (Aduhelm ™) - is the first therapy to demonstrate that removing amyloid, one of the hallmarks of Alzheimer's disease, from the brain is reasonably likely to reduce cognitive and functional decline in people living with early Alzheimer's. (alz.org)
- In support of research on Alzheimer disease and related disorders, the Neuropathology Core analyzes tissues and other biological samples from volunteers in the Stanford Alzheimer's Disease Research Center (ADRC). (stanford.edu)
- Her research program combines her background in diagnostic neuropathology, knowledge of developmental neuroscience, and state-of-the-art cellular and molecular technologies to advance the understanding of Alzheimer's disease and related dementias. (stanford.edu)
- She is currently applying single-cell methods to human brain to dissect the contributions of distinct cell types to Alzheimer's disease pathogenesis and investigate the mechanisms of tau-mediated neurodegeneration in human brain. (stanford.edu)
- Jacquelyn Revere, 35, moved back home at 29 to care for her mother, who had developed Alzheimer's disease. (npr.org)
- ntly, findings were published in the Journal of Alzheimer's Disease that may help explain why people who are susceptible to stress are at more risk of developing Alzheimer's and why - increasingly - we are finding evidence that physical activity, which reduces stress levels, may reduce the chances of developing Alzheimer's . (alz.org)
- Interestingly, previous studies have shown that people with Alzheimer's disease have a reduced level of CRF. (alz.org)
- However, in mice with Alzheimer's disease, moderate exercise restored the normal function of the CRF system allowing its memory enhancing effects. (alz.org)
- This study of biological stress and its effects is a science that continues to make advances today by connecting stress to illness, including Alzheimer's disease . (alz.org)
- Corticotropin-Releasing Factor Receptor 1 Activation During Exposure to Novelty Stress Protects Against Alzheimer's Disease-Like Cognitive Decline in AßPP/PS1 Mice , Journal of Alzheimer's Disease. (alz.org)
- Learn how Alzheimer's disease affects the brain. (alz.org)
- Alzheimer's disease (AD) is often seen with a wide range of comorbid diseases that are also more common in older individuals. (medscape.com)
- Are you familiar with the comorbidities seen with Alzheimer's disease? (medscape.com)
Diagnosis5
- Even if all signs point toward liver disease, your veterinarian can't provide a definitive diagnosis without a blood test. (petfinder.com)
- [1] Diagnosis of early disease is by finding the parasite in the blood using a microscope or detecting its DNA by polymerase chain reaction . (wikipedia.org)
- Diagnosis of these disease will likely include a physical exam, detailed history, neurological exam, and specialized testing. (bellaonline.com)
- Cutaneous implantation and systemic mycoses are neglected diseases that affect millions of individuals worldwide, especially in low-income countries where their management is suboptimum because challenges in diagnosis and therapeutic options are substantial issues. (thelancet.com)
- Rupal J. Shah, MD, addresses the impact that health disparities have on the lives of patients both awaiting a diagnosis of or being treated for interstitial lung disease. (medscape.com)
Symptoms18
- 2 years, meningococcal disease can have nonspecific symptoms. (cdc.gov)
- Alzheimer's is a progressive disease, where dementia symptoms gradually worsen over a number of years. (alz.org)
- The center's multidisciplinary team is committed to providing patients across their lifespan with highly personalized care to manage their symptoms associated with the disease so they can live as normal a life as possible. (bmc.org)
- Signs and symptoms of Lyme disease vary by disease stage. (medscape.com)
- The symptoms of brain diseases vary widely, depending on the specific problem. (medlineplus.gov)
- Individuals with the adult-onset form of Huntington disease usually live about 15 to 20 years after signs and symptoms begin. (medlineplus.gov)
- People with 36 to 39 CAG repeats may or may not develop the signs and symptoms of Huntington disease, while people with 40 or more repeats almost always develop the disorder. (medlineplus.gov)
- The dysfunction and eventual death of neurons in certain areas of the brain underlie the signs and symptoms of Huntington disease. (medlineplus.gov)
- The indicators of liver disease in cats can be a bit ambiguous because they are similar to symptoms of many other diseases and illnesses. (petfinder.com)
- More symptoms of more severe disease might include seizures, high fever, dark urine and a distended abdomen. (petfinder.com)
- What Are the Signs & Symptoms of Sickle Cell Disease? (kidshealth.org)
- [1] After four to eight weeks, untreated individuals enter the chronic phase of disease, which in most cases does not result in further symptoms. (wikipedia.org)
- When used in chronic disease, medication may delay or prevent the development of end-stage symptoms. (wikipedia.org)
- [2] When present, the symptoms are typically minor and not specific to any particular disease. (wikipedia.org)
- These diseases can lead to a variety of symptoms like excessive thirst, changes in hair coat, behavior, increased blood pressure etc. (purdue.edu)
- Onset of the symptoms of this disease varies, as does progression, and prognosis. (bellaonline.com)
- Many of the complications of mitochondrial myopathy overlap with other diseases, and effective treatments for managing these symptoms exist. (bellaonline.com)
- Pain and tightness in the chest are common symptoms of coronary artery disease, but many prescription medications can offer relief. (sharecare.com)
Neurodegenerative2
- Consequently, cancer, neurodegenerative diseases or developmental disorders may arise. (mpg.de)
- Telomerase reverse transcriptase and neurodegenerative diseases. (bvsalud.org)
Infectious disease6
- Mathematical models of human mobility have demonstrated a great potential for infectious disease epidemiology in contexts of data scarcity. (biomedcentral.com)
- The usefulness of these models appears in data-scarce contexts, such as during infectious disease epidemics in low-income countries, when forecasting the best possible allocation of resources becomes necessary. (biomedcentral.com)
- Suffers of the infectious disease that typically attacks the lungs had an average of three years to live. (yahoo.com)
- Thanks, your message has been sent to Bureau of Infectious Disease and Laboratory Sciences! (mass.gov)
- The Massachusetts General and Brigham and Women's Hospitals have integrated their Infectious Disease Fellowship Training Programs to offer unparalleled opportunities for clinical and research training in Infectious Diseases at Harvard Medical School. (massgeneral.org)
- The Adult Infectious Disease and Basic Microbiological Mechanisms Training Program is a Harvard-wide training program dedicated to the education of those infectious disease fellows and PhD postdoctoral fellows interested in pursuing careers as physician-scientists or scientists with a focus on investigation into important questions in non-HIV microbiology and infectious diseases. (massgeneral.org)
Emerging Infectio4
- Emerging Infectious Diseases , 29 (3), 477-483. (cdc.gov)
- Emerging Infectious Diseases , 29 (3), 484-492. (cdc.gov)
- Its experts monitor emerging infectious diseases and risk factors in the general population. (rki.de)
- What we are seeing now looks more and more like a dramatic resurgence of the threat from emerging and re-emerging infectious diseases. (cubasi.cu)
Genetics1
- History of genetic disease: the molecular genetics of Huntington disease - a history. (medlineplus.gov)
Affects8
- Although doctors in the 1800s first described lupus as a skin disease because of the rash it commonly produces, the systemic form, which is most common, actually affects many organs, including the joints, kidneys, brain, and heart. (healthline.com)
- Huntington disease affects an estimated 3 to 7 per 100,000 people of European ancestry. (medlineplus.gov)
- The disease affects 100,000 people in the United States and millions around the world, the majority of whom are of African or Hispanic descent. (ucla.edu)
- Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects some 8 million people worldwide. (news-medical.net)
- [1] The disease affects more than 150 types of animals. (wikipedia.org)
- A disease is defined as a rare or orphan disease when it affects fewer than 200,000 people in the United States. (phrma.org)
- These diseases are considered to be a neuromusclar disease, although this disease affects all the cells of the body. (bellaonline.com)
- Thus, this disease affects multiple organs of the body. (bellaonline.com)
Control of neglected tropical1
- It is widely advocated that integrated strategies for the control of neglected tropical diseases (NTDs) are cost-effective in comparison to vertical disease-specific programmes. (biomedcentral.com)
Disorders5
- Patients with blood disorders receive consultation and treatment for a broad range of benign conditions, such as hemoglobinopathies (sickle cell anemia and thalassemia), hemochromatosis, bleeding and thrombotic disorders (von Willebrand's disease and hemophilia), hypercoagulable states, myeloproliferative disorders, myelodysplasia and anemia, and malignancies such as leukemia, lymphoma and myeloma. (bmc.org)
- Genetic abnormalities of the blood, such as sickle cell disease, are a main focus of the program, but it also provides evaluation and ongoing care for children and adolescents with a variety of blood disorders and "orphan" illnesses. (bmc.org)
- Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. (elsevier.com)
- The new list includes a range of internationally recognized occupational diseases, from illnesses caused by chemical, physical and biological agents to respiratory and skin diseases, musculoskeletal disorders and occupational cancer. (ilo.org)
- The open items allow the recognition of the occupational origin of diseases not specified in the list if a link is established between exposure to risk factors arising from work activities and the disorders contracted by the worker. (ilo.org)
Severe7
- Kohn has already applied the same concept to successfully treat several immune system deficiencies, including a cure for a form of severe combined immune deficiency , also known as bubble baby disease. (ucla.edu)
- Breaks and rearrangements in the genome can lead to severe diseases, even if all genes remain intact. (mpg.de)
- [4] [16] In rare cases (less than 1-5%), infected individuals develop severe acute disease, which can involve inflammation of the heart muscle , fluid accumulation around the heart , and inflammation of the brain and surrounding tissues , and may be life-threatening. (wikipedia.org)
- A related study presented at the Digestive Disease Week conference (DDW 2010) last week in New Orleans found that more than half of people with compensated cirrhosis (mostly due to hepatitis C) showed signs of neurocognitive impairment, indicating that mild hepatic encephalopathy is common even among individuals without severe liver disease. (hivandhepatitis.com)
- Low levels of ceruloplasmin can also be found in cases of Menkes disease, hereditary aceruloplasminemia, protein-losing enteropathy including celiac disease and severe hepatic insufficiency, and in heterozygous carriers of WD. (medscape.com)
- This disease is characterized by severe signs like vomiting, diarrhea, poor appetite, and electrolyte abnormalities. (purdue.edu)
- Heart diseases are pretty severe with some big complications later in life, so they need to be treated as soon as they can before some other problem arises. (drchetan.com)
Sickle Cell Di17
- BMC's Center of Excellence in Sickle Cell Disease is the largest center of its kind in New England, serving more than 450 patients annually, from newborns to adults. (bmc.org)
- For Evie Junior, living with sickle cell disease has been like running a marathon. (ucla.edu)
- In sickle cell disease, a genetic mutation causes the blood-forming stem cells - which give rise to all blood and immune cells - to produce hard, sickle-shaped red blood cells. (ucla.edu)
- The big worry with sickle cell disease is that you're going to die young from some type of complications or damage to your organs," he said. (ucla.edu)
- But sickle cell disease has proven more difficult to treat with gene therapy than those other conditions. (ucla.edu)
- Sickle cell disease is a group of conditions in which red blood cells are not shaped as they should be. (kidshealth.org)
- Kids who have sickle cell disease may feel pain in different parts of the body when blood vessels get clogged with sickle cells. (kidshealth.org)
- Because kids with sickle cell disease don't have enough normal red blood cells, they may get tired a lot. (kidshealth.org)
- Sickle cell disease is an inherited (say: in-HAIR-uh-ted) disease. (kidshealth.org)
- How Is Sickle Cell Disease Treated? (kidshealth.org)
- Kids with sickle cell disease should get all recommended vaccinations . (kidshealth.org)
- Taking medicine does not cure sickle cell disease, but it can help keep kids who have it from getting sick. (kidshealth.org)
- Kids with sickle cell disease may need to go to the hospital if they have a lot of pain or a serious infection. (kidshealth.org)
- Sometimes kids with sickle cell disease need blood transfusions (say: trans-FEW-zyuns). (kidshealth.org)
- In some cases, a bone marrow transplant can cure sickle cell disease. (kidshealth.org)
- They are risky and not right for everyone, so scientists are working on finding other ways to cure sickle cell disease. (kidshealth.org)
- Having sickle cell disease can be frustrating and sometimes painful. (kidshealth.org)
Noncommunicable2
- The repository of legislation on risk factors offers Member States organized, systematized, and updated legal information on the main risk factors for noncommunicable diseases (NCDs). (bvsalud.org)
- The system is jointly managed by PAHO's Noncommunicable Diseases and Health Mental Department, and by the Organization's Office of Legal Counsel. (bvsalud.org)
20171
- http://www.who.int/neglected_diseases/9789241564540/en/ (accessed May 15, 2017). (thelancet.com)
Mitochondrial diseases3
- His research interests include mitochondrial diseases, nerve and muscle pathology, pediatric neuro-oncology, and transgenic mouse pathology. (stanford.edu)
- For example, Edison Pharmaceitical is currently testing a drug specifically for mitochondrial diseases in human clinical trials. (bellaonline.com)
- Edison drugs target FA, mitochondrial diseases. (bellaonline.com)
Therapies2
- These pages contain background information on some of the most common medications and therapies used to treat rheumatic disease, such as how they work, common dosages, safety tips, possible side effects, risks and things you should discuss with your health care providers if you are taking or considering these treatments. (rheumatology.org)
- America's biopharmaceutical researchers are leveraging new technologies and the growing understanding of the genetic basis for many rare diseases to develop groundbreaking therapies to meet this unmet need. (phrma.org)
World's3
- Earlier this year, President Bush said the United States would spend $350 million over five years to fight seven of the world's most common parasitic and bacterial diseases affecting hundreds of millions of people in tropical regions of the world. (voanews.com)
- But many other diseases are equally widespread and cause massive suffering in scores of countries, yet rarely seem to capture the world's attention. (voanews.com)
- Produced by the National Library of Medicine, the world's largest medical library, it brings you information about diseases, conditions, and wellness issues in language you can understand. (medlineplus.gov)
Chronic diseases3
- The present study aims to address aspects of children with chronic diseases hospitalization and the contributions of Lacanian psychoanalysis. (bvsalud.org)
- Anchored in such points, the possibilities and limits of the analyst's performance in the work with children with chronic diseases in the hospital are presented. (bvsalud.org)
- Key Laboratory of Major Chronic Diseases of Nervous System of Liaoning Province, Health Sciences Institute of China Medical University, Shenyang, China. (bvsalud.org)
Autoimmune diseases8
- Some autoimmune diseases target only one organ. (healthline.com)
- Below we provide an overview of some of the most common autoimmune diseases. (healthline.com)
- According to a 2014 study , women get autoimmune diseases at a rate of about 2 to 1 compared to men - 6.4% of women versus 2.7% of men. (healthline.com)
- Some autoimmune diseases are more common in certain ethnic groups. (healthline.com)
- Certain autoimmune diseases, such as multiple sclerosis and lupus, run in families . (healthline.com)
- Because the incidence of autoimmune diseases is rising, researchers suspect environmental factors like infections and exposure to chemicals or solvents might also be involved. (healthline.com)
- Researchers don't know exactly what causes autoimmune diseases. (healthline.com)
- There are more than 80 autoimmune diseases . (healthline.com)
Patients18
- Visit our new platform where rare disease patients can fundraise, communicate and advocate. (rarediseases.org)
- In patients with late disease, the typical physical finding is arthritis. (medscape.com)
- With appropriate antibiotic treatment, most patients with early-stage Lyme disease recover rapidly and completely. (medscape.com)
- HIVAN was always considered synonymous with HIV renal involvement but now accounts for less than 40% of the cases of renal disease found in HIV infected patients. (medscape.com)
- In a head-to-head comparison, entecavir (Baraclude) demonstrated superior virological efficacy compared to adefovir (Hepsera) in hepatitis B patients with decompensated liver disease. (hivandhepatitis.com)
- Clinically, his main interests are the care of patients with pulmonary hypertension and autoimmune-related lung disease. (ohsu.edu)
- She cares for patients in both the outpatient and inpatient setting, and provides compassionate, thoughtful, communicative and individualized care to patients and their families as they navigate through the disease course. (ohsu.edu)
- We've seen incredible advances in the development of medicines to treat patients with rare diseases as researchers uncover the molecular and genomic drivers of many conditions. (phrma.org)
- Additionally, due to the inherently small population of patients with a rare disease, recruiting for and conducting clinical trials can be difficult. (phrma.org)
- Rare Diseases Day 2013 raises awareness of rare diseases and their impact on the daily lives of patients and their families all over the world. (biomedcentral.com)
- The cost-effectiveness of enzyme replacement therapy (ERT) compared to standard medical care was evaluated in the Dutch cohort of patients with Fabry disease. (biomedcentral.com)
- Patients with liver disease have been steadily increasing as a result of alcohol abuse, inhaling harmful gases, eating contaminated food, heavy drinking of local beverage and drugs. (easychair.org)
- Tumor necrosis factor-alpha (TNF-alpha) is considered to be 1 of the factors that induce vasculitis, including coronary artery aneurysm (CA), in Kawasaki disease (KD), because the blood concentration of TNF-alpha is higher in patients with CA compared with those without. (nih.gov)
- As such, the value of these tests in following patients with advanced disease is uncertain . (medscape.com)
- However, the AAO states that it is not currently recommended for monitoring disease progression in patients with IRDs. (medscape.com)
- Murugeswari P, Shukla D, Kim R, Namperumalsamy P, Stitt AW, Muthukkaruppan V. Angiogenic potential of vitreous from Proliferative Diabetic Retinopathy and Eales' Disease patients. (medscape.com)
- Kharel Sitaula R, Iyer V, Noronha V, Dutta Majumder P, Biswas J. Role of high-resolution computerized tomography chest in identifying tubercular etiology in patients diagnosed as Eales' disease. (medscape.com)
- The main objective of Rare Disease Day is to raise awareness amongst the general public and decision-makers about rare diseases and their impact on patients' lives. (bvs.br)
Genes1
- This disease is caused by a problem in your genes and gets worse over time. (webmd.com)
Outbreaks6
- Although meningococcal disease outbreaks can occur anywhere in the world, they are most common in the African meningitis belt, where large-scale epidemics occur every 5-12 years. (cdc.gov)
- The Hajj pilgrimage to Saudi Arabia also has been associated with outbreaks of meningococcal disease among returning pilgrims and their contacts, including 4 cases in travelers from the United States during a large Hajj-associated outbreak in 2000. (cdc.gov)
- Travel Health Notices inform travelers and clinicians about current health issues that impact travelers' health, like disease outbreaks, special events or gatherings, and natural disasters, in destinations around the world. (cdc.gov)
- The country is experiencing outbreaks of infectious diseases, and adequate health care is currently not available in most of the country. (cdc.gov)
- The Robert Koch Institute analyses pathogens and disease outbreaks, suggests measures for prevention and intervention, fills knowledge gaps and ensures the quality of health screening and care. (rki.de)
- Africa CDC strengthens the capacity and capability of Africa's public health institutions as well as partnerships to detect and respond quickly and effectively to disease threats and outbreaks, based on data-driven interventions and programmes. (africacdc.org)
Zoonotic3
- National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) are at the forefront of many of these efforts. (cdc.gov)
- A recent article published in the journal Frontiers in Tropical Diseases assessed the threat of emerging zoonotic and vector-borne tropical diseases. (news-medical.net)
- HEARTGARD ® Plus (ivermectin/pyrantel), the #1 veterinarian-recommended heartworm preventive, prevents heartworm disease and treats and controls roundworms and hookworms that can cause zoonotic disease in people, including children. (petfinder.com)
Carried Chagas disease1
- [12] Large-scale population migrations have carried Chagas disease to new regions, which include the United States and many European countries. (wikipedia.org)
Illnesses4
- See Lyme Disease and 4 Emerging Tick-Borne Illnesses , a Critical Images slideshow, to help identify and treat several tick-borne conditions. (medscape.com)
- In 2012, a mild winter, early spring, and hot summer set the stage for an outbreak of West Nile virus disease in the United States, resulting in more than 5,600 illnesses and 286 deaths. (cdc.gov)
- On the basis of a recent case report, [ 25 ] it is recommended that all subjects presenting with symptomatic or asymptomatic liver disease with no apparent cause, or with extrapyramidal features along with a past or family history of similar hepatic or neurological illnesses in other siblings, should be screened for WD. (medscape.com)
- Mosquito-borne illnesses represent an enormous burden of disease on a global level and have been a menacing threat to mankind since early civilization. (ebmedicine.net)
Progresses2
- Meningococcal disease progresses rapidly and has a case-fatality rate of 10%-15%, even with antimicrobial drug treatment. (cdc.gov)
- As the disease progresses, these movements become more pronounced. (medlineplus.gov)
Celiac disease4
- The CDF Turkey Trot is our signature event for you to raise funds to support celiac disease research. (celiac.org)
- While the format may be new, the Celiac Disease Foundation's commitment to raising funds and awareness for celiac disease is unwavering, and we hope we can continue to count on your steadfast support. (celiac.org)
- Mark your calendar for November 14 & 15, and look for our August 15 registration announcement in your email, as together we go the distance for a cure for celiac disease! (celiac.org)
- Medical information provided on this site has been prepared by medical professionals and reviewed by the Celiac Disease Foundation's Medical Advisory Board for accuracy. (celiac.org)
Parasitic2
- Chagas disease , also known as American trypanosomiasis , is a tropical parasitic disease caused by Trypanosoma cruzi . (wikipedia.org)
- Nobel Prizes Three scientists from Japan, China and Ireland whose discoveries led to the development of potent new drugs against parasitic diseases such as malaria and elephantiasis have won the Nobel Prize in Physiology or Medicine. (abc.net.au)
Infections3
- [2] [4] Up to 45% of people with chronic infections develop heart disease 10-30 years after the initial illness, which can lead to heart failure . (wikipedia.org)
- Early infections are treatable with the medications benznidazole or nifurtimox , which usually cure the disease if given shortly after the person is infected, but become less effective the longer a person has had Chagas disease. (wikipedia.org)
- Most chronic infections are asymptomatic, which is referred to as indeterminate chronic Chagas disease. (wikipedia.org)
Humans5
- [ 1 ] The disease is transmitted to humans via tick bites, from infected ticks of the genus Ixodes . (medscape.com)
- Warming temperatures in Alaska have led to increases in vole populations, which can spread diseases like Alaskapox to humans. (cdc.gov)
- As the difference between environmental temperatures and human body temperatures narrows, new fungal diseases may emerge as fungi become more adapted to surviving in humans. (cdc.gov)
- This series highlights the research published in Orphanet Journal of Rare Diseases and Parasites & Vectors on some of the genetic and infectious rare diseases that affect humans. (biomedcentral.com)
- Our often-used metaphor of humans waging "war" on infectious diseases and on the microbes that cause them invites comparison with the Battle of the Alamo. (cdc.gov)
Renal4
- However, with 35% of the world HIV population still untreated by HAART, both of these HIV-induced renal diseases still occasionally try to recapture their glory days of relentless glomerular injury and progressive fibrosis. (medscape.com)
- Moreover, HAART -related renal disease has also been dominating the discussions recently as it has significantly eliminated both HIVAN and HIVICK through sustained viral control and has even caused regression of these lesions after they have developed. (medscape.com)
- You have to give credit to HIVAN for such a consistent career and no matter what happens in this tournament, HIVAN is likely a certainty to be voted into the viral-mediated renal disease Hall of Fame. (medscape.com)
- Fabry disease is an X-linked lysosomal storage disorder caused by α-galactosidase A deficiency leading to renal, cardiac, cerebrovascular disease and premature death. (biomedcentral.com)
Sexually Transmit2
- An interactive internet-based continuing education course on sexually transmitted diseases for physicians and midwives in Peru. (bvsalud.org)
- The objective of this study was to evaluate an interactive Internet -based CE course on Sexually Transmitted Diseases ( STDs ) management for clinicians in Peru . (bvsalud.org)
Interstitial lung di1
- Her academic and clinical interests include medical education, interstitial lung disease, and sarcoidosis. (ohsu.edu)
Epidemics2
- Meningococcal disease is hyperendemic in this region, and periodic epidemics during the dry season (December-June) reach an incidence of up to 1,000 cases per 100,000 population. (cdc.gov)
- Diseases and epidemics of the 19th century included long-standing epidemic threats such as smallpox, typhus, yellow fever, and scarlet fever. (yahoo.com)
Tropical diseases7
- The Global Network for Neglected Tropical Diseases has a new high-profile advocate: former Health and Human Services Secretary Tommy Thompson, who will be serving as the organization's global ambassador. (voanews.com)
- Neglected tropical diseases -- they are really from biblical times,' he said. (voanews.com)
- The Global Network for Neglected Tropical Diseases is targeting 14 NTPs worldwide, all of which are readily treatable at a minimal cost. (voanews.com)
- Fifty cents [half a US dollar] per person per year is all we need in order to defeat these neglected tropical diseases. (voanews.com)
- Despite growing awareness of the importance of controlling neglected tropical diseases as a contribution to poverty alleviation and achieving the Millennium Development Goals, there is a need to up-scale progr. (biomedcentral.com)
- Sustaining the drive to overcome the global impact of neglected tropical diseases: second WHO report on neglected tropical diseases. (thelancet.com)
- Report of the tenth meeting of the WHO strategic and technical advisory group for neglected tropical diseases. (thelancet.com)
Content1
- This Collection highlights the newest top-viewed content from Prostate Cancer and Prostatic Diseases. (nature.com)
Complications1
- As a child growing up in the Bronx, New York, Junior had to have his gall bladder and spleen removed due to complications from the disease, but he refused to let his condition limit him. (ucla.edu)
Dengue2
- Will warmer temperatures worsen the burden of insect-borne diseases such as malaria and dengue fever? (sej.org)
- You have heard that there is a current outbreak of dengue on the island, but you have never seen the disease before, so you need to quickly assess whether your patient has dengue and how to manage her disease. (ebmedicine.net)
Kidney2
- HIVAN (HIV-associated nephropathy) and HIVICK (HIV immune complex disease of the kidney) used to be perennial powerhouses garnering worldwide attention. (medscape.com)
- Organoids generated from dozens of tissues and organs available commercially, or accessible through published protocols include patient-derived models of liver , heart, pancreas, brain, GI tract, kidney, and recently, of human airways suitable for drug and vaccine development and for studying infectious human respiratory diseases. (corning.com)
NCDs1
- National trends in age-standardised death rates (ASDRs) for non-communicable diseases (NCDs) in South Africa (SA) were identified between 1997 and 2010. (bvsalud.org)
Addison's Disease1
- In addition, there are diseases characterized by a lack of these hormones, including hypoadrenocorticism (also called Addison's Disease). (purdue.edu)
Treatments for rare diseases2
- The ODA provides incentives for rare disease R&D, as it can be especially challenging to develop new treatments for rare diseases. (phrma.org)
- Researching and developing new treatments for rare diseases is time consuming, complex, and often expensive. (medlineplus.gov)
Pathogens4
- Infectious Diseases Now (formerly Médecine et Maladies Infectieuses) publishes in English the highest quality original material, both scientific and clinical, on the various infectious pathologies and their pathogens. (em-consulte.com)
- Official journal of the SPILF , French Infectious Diseases Society ( Société de Pathologie Infectieuse de Langue Française ), it publishes scientific articles in English , which address the various infectious pathologies and their pathogens. (em-consulte.com)
- After proofs of concept through successes of the above mentioned two vaccines, our long-term goals are to apply these principles and technologies to other viral and/or non-viral pathogens to develop more vaccines to fight many more infectious diseases to meet the wide and urgent needs of global public health. (cincinnatichildrens.org)
- Since the 1980s, nearly 40 new pathogens have been identified as human disease threats, and 12% of known human pathogens have been classified as either emerging or remerging. (cdc.gov)
7,0001
- According to the National Institutes of Health (NIH), 30 million Americans, or 10 percent of the population, have one of the approximately 7,000 known rare diseases. (phrma.org)
Inflammation2
- Oxidative stress and inflammation are involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). (clinicaltrials.gov)
- Bhooma V, Sulochana KN, Biswas J, Ramakrishnan S. Eales' disease: accumulation of reactive oxygen intermediates and lipid peroxides and decrease of antioxidants causing inflammation, neovascularization and retinal damage. (medscape.com)
Lyme5
- Lyme disease, the most common vector-borne illness in the United States, is a multisystem illness usually caused by infection with the spirochete Borrelia burgdorferi (see the image below) and the body's immune response to the infection. (medscape.com)
- Antibiotic selection, route of administration, and duration of therapy for Lyme disease are guided by the patient's clinical manifestations and stage of disease, as well as the presence of any concomitant medical conditions or allergies. (medscape.com)
- Lyme disease, West Nile virus disease, and Valley fever. (cdc.gov)
- The geographic ranges where ticks spread Lyme disease, anaplasmosis, ehrlichiosis, and spotted fever rickettsiosis have expanded, and experts predict that tickborne diseases will continue to increase and perhaps worsen. (cdc.gov)
- The most common tick-borne diseases in Massachusetts are Lyme Disease, Babesiosis, and Anaplasmosis. (mass.gov)
Common9
- Adult-onset Huntington disease, the most common form of this disorder, usually appears in a person's thirties or forties. (medlineplus.gov)
- A less common form of Huntington disease known as the juvenile form begins in childhood or adolescence. (medlineplus.gov)
- To understand climate change's impact, it's important to look at some of the common ways these diseases spread-through mosquito and tick bites, contact with animals, fungi, and water. (cdc.gov)
- What diseases were common in the 19th century? (yahoo.com)
- The Purdue Small Animal Internal Medicine service specializes in identifying diseases characterized by either lack of production of thyroid hormone (hypothyroidism, more common in dogs) or overproduction of thyroid hormone (hyperthyroidism, more common in cats). (purdue.edu)
- Hyperthyroidism is a common disease in older cats and is most commonly caused by a benign tumor of the thyroid gland (though occasionally these tumors are more aggressive). (purdue.edu)
- Coronary artery disease (otherwise known as CAD) is the most common type of heart disease in the United States and the leading cause of death among American men and women. (sharecare.com)
- A relatively common but under-diagnosed childhood disease is getting special attention at a unique clinic in Kansas City. (publicnewsservice.org)
- This pathological process is referred to as autoimmune vesiculobullous disease and the most common diseases are pemphigus, erythema multiforme, lichen planus and pemphigoid. (bvsalud.org)
Coronary heart d1
- This lack of blood-flow can leave your heart without enough oxygen, causing coronary heart disease. (diabetes.org)
HUNTINGTON DISEASE7
- Many people with Huntington disease develop involuntary jerking or twitching movements known as chorea. (medlineplus.gov)
- Mutations in the HTT gene cause Huntington disease. (medlineplus.gov)
- In people with Huntington disease, the CAG segment is repeated 36 to more than 120 times. (medlineplus.gov)
- In rare cases, an individual with Huntington disease does not have a parent with the disorder. (medlineplus.gov)
- People with the adult-onset form of Huntington disease typically have 40 to 50 CAG repeats in the HTT gene, while people with the juvenile form of the disorder tend to have more than 60 CAG repeats. (medlineplus.gov)
- Individuals who have 27 to 35 CAG repeats in the HTT gene do not develop Huntington disease, but they are at risk of having children who will develop the disorder. (medlineplus.gov)
- As the gene is passed from parent to child, the size of the CAG trinucleotide repeat may lengthen into the range associated with Huntington disease (36 repeats or more). (medlineplus.gov)
Fellowship Program2
- For more information, visit the Infectious Diseases Fellowship Program website . (massgeneral.org)
- Current Fellows of the Cardiovascular Disease Fellowship Program at UPMC in Central Pa. (upmc.com)
Infection3
- Both asymptomatic carriers and people with overt meningococcal disease can be sources of infection. (cdc.gov)
- Chagas disease ( T. cruzi infection) is also referred to as American trypanosomiasis. (news-medical.net)
- Fifth disease is a viral infection that most often happens in children. (epnet.com)
People15
- Approximately 30% of people with meningococcal disease present with meningococcal sepsis, known as meningococcemia. (cdc.gov)
- People with younger-onset Alzheimer's can be in the early, middle or late stage of the disease. (alz.org)
- Yet some people are more likely to get an autoimmune disease than others. (healthline.com)
- According to a 2012 study , about 50% of people with MS need help walking within 15 years after the disease starts. (healthline.com)
- Milder winters, warmer summers, and fewer days of frost make it easier for these and other infectious diseases to expand into new geographic areas and infect more people. (cdc.gov)
- More than 200 people for every 100,000 in the United States died of the disease. (yahoo.com)
- People who haven't been vaccinated for tetanus can get the disease by stepping on a dirty nail or getting cut by a dirty tool. (infoplease.com)
- [3] Most people with the disease are poor , [11] and most do not realize they are infected. (wikipedia.org)
- Advanced liver disease caused by hepatitis B virus (HBV) -- including hepatocellular carcinoma (HCC) and decompensated cirrhosis -- accounted for more than 40% of deaths of people with chronic hepatitis B in a large health maintenance organization, researchers reported in the December 12, 2012, advance online edition of Hepatology . (hivandhepatitis.com)
- The diseases can also make people more susceptible to other, more deadly afflictions, such as HIV. (voanews.com)
- These diseases can affect people differently and with differing degrees of severity. (bellaonline.com)
- People with diabetes are twice as likely to have heart disease or a stroke than people without diabetes. (diabetes.org)
- Cardiovascular disease (CVD), where the heart and blood vessels are negatively impacted, is the number one cause of death in people living with diabetes, resulting in 2/3 of deaths in people with type 2 diabetes. (diabetes.org)
- Annually, nearly 700 million people are afflicted with diseases transmitted by mosquitoes. (ebmedicine.net)
- In the United States, diseases that each affect less than 200,000 people are called "rare diseases. (medlineplus.gov)